Clinical trials: Focus Groups, open to volunteers
Breast Cancer Invasive, Prostate Cancer
AVI Didactic Experience for Latinx Patient Treatment Adherence and Non-English Speaker Trial Enrollment Study in Rad Onc
The study aims to develop educational media interventions to prepare Latinx Spanish-speaking radiation oncology patients for a course of breast or prostate cancer radiation therapy and to foster receptivity and informed…
- Trial name
- ADELANTE (NCT05351424)
- Testing
- Audiovisual Intervention- Radiation Therapy Education, ASTRO Radiation Therapy for Breast or Prostate Cancer Brochure, Audiovisual Intervention- Cancer Clinical Trials Education
- Where
- 2 sites in United States
- Volunteers
- 194 people
- Sponsor
- Columbia University
Clinical Competence
Evaluation of a Chatbot With CALMO (Chatbot-Assisted Learning Model) to Enhance Clinical Learning in Nursing Students
The present proposed study will design and develop a chatbot to support graduating nursing students' clinical learning. The efficacy of this chatbot technology will be evaluated, using a mixed methods quasi-experimental design.
- Trial name
- CALMO (NCT06780228)
- Testing
- chatbot-assisted clinical learning
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Caritas Institute of Higher Education
Drug Resistant Epilepsy, Epilepsy
A Pilot Study to Evaluate the Efficacy and Safety of NaviFUS™ System Neuromodulating Treatment for Patients With Drug Resistant Epilepsy
This will be a prospective, pilot, open-label, two-arm, parallel-group, randomized study to evaluate the efficacy and safety of low-intensity focused ultrasound (LIFU) neuromodulation using NaviFUS System in patients with…
- Conditions
- Drug Resistant Epilepsy, Epilepsy, Epilepsy, Temporal Lobe, Seizures, Focal
- Trial name
- NCT06492720
- Testing
- Focused ultrasound (FUS) treatment
- Where
- Taiwan
- Volunteers
- 16 people
- Sponsor
- NaviFUS Corporation
Malnutrition
Epidemiology and Management of Malnutrition of Patients Hospitalized at the Pitié-Salpêtrière Hospital: a One-day Survey Combined With Focus Groups (Mixed Methods)
According to the literature, malnutrition affects between 30% and 50% of hospitalized patients. The most recent survey on the prevalence of malnutrition in hospitals in France dates back to 2003, and at the Pitié Salpêtrière…
- Trial name
- EPIDENUT_PSL (NCT06317402)
- Testing
- malnutrition questionary
- Where
- France
- Volunteers
- 385 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Depression, Anxiety, Visual Impairment
Developing Evidence-Based Cognitive Approaches to Improve Adjustment to Vision Loss
The goal of this study is to develop and pilot test a therapeutic strategy combining cognitive behavioral therapy (CBT) with mindfulness practices tailored for individuals adjusting to vision loss.
- Conditions
- Depression, Anxiety, Visual Impairment, Adjustment, Adjustment Disorder With Anxious Mood
- Trial name
- NCT07073521
- Testing
- Integrated Cognitive Behavioral Therapy (CBT) & Mindfulness Group Intervention for Adjustment to Vision Loss
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- The Chicago Lighthouse
Dry Eye, Evaporative Dry Eye Disease
Microbiome-Focused Food Supplement for Evaporative Dry Eye Due to Meibomian Gland Dysfunction
Dry eye disease (DED) is a common chronic condition characterized by ocular surface discomfort and tear film instability. Evaporative DED associated with meibomian gland dysfunction (MGD) is a frequent phenotype and is often…
- Conditions
- Dry Eye, Evaporative Dry Eye Disease, Meibomian Gland Dysfunction (Disorder)
- Trial name
- NCT07453212
- Testing
- Dietary Supplement: Microbiome-targeted oral supplement
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Varol TUNALI
Neurofibromatosis Type 1, Neurofibroma
Development of Patient-Reported Outcome Measures Assessing Tumor Visibility and Appearance Concerns in Neurofibromatosis Type 1: A Qualitative Study
Background: Neurofibromatosis 1 (NF1) is a disease that causes tumors to grow along the nerves. These include plexiform neurofibromas (pNF) and cutaneous neurofibromas (cNF). Both pNF and cNF can be visible to other people.
- Trial name
- NCT06880991
- Testing
- Arm 1
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- National Cancer Institute (NCI)
Epilepsy, Drug Resistant
Subthalamic Nucleus Electrical Stimulation for Drug-resistant Focal Motor Epilepsy
The primary objective of this research is to study the efficacy and safety of deep brain stimulation (DBS) of subthalamic nucleus (STN) as adjunctive therapy for reducing the frequency of seizures in drug-resistant focal motor…
- Trial name
- STEM (NCT06248333)
- Testing
- STN-DBS ON, STN-DBS OFF
- Where
- China
- Volunteers
- 33 people
- Sponsor
- Xuanwu Hospital, Beijing
Rotator Cuff-related Shoulder Pain, Shoulder Osteoarthritis
Could a Feedback Device Help Manage Work-related Shoulder Disorders?
Work-related shoulder pain is a common problem with significant socio-economic repercussions. The impact of these disorders on workers is considerable, particularly in terms of pain, disability and reduced quality of life.
- Conditions
- Rotator Cuff-related Shoulder Pain, Shoulder Osteoarthritis, Rheumatoid Arthritis (RA)
- Trial name
- NCT06693479
- Testing
- Shoulder watch load (SWL) feedback, Education
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- Laval University
Paediatric Asthma
Design, Development and Evaluation of a Digital Health Assistant for Paediatric Asthma
This study is to evaluate the efficacy of the digital health assistant (DHA) "Alex" in improving asthma control in asthmatic children and adolescents aged 10 to 19 compared to their baseline values.
- Trial name
- ALEX (NCT07472283)
- Testing
- Phase I (months 1-3): DHA core functionality, Phase II (months 3-6): platform augmentation, Embedded qualitative study
- Where
- 5 sites in Romania
- Volunteers
- 42 people
- Sponsor
- University Children's Hospital Basel
Drug-resistant Focal Epilepsies in Pediatric Population
Genetic and Electrophysiologic Study in Focal Drug-resistant Epilepsies
Brain somatic mutations are increasingly recognized as a major cause of focal epilepsies. These include mTOR pathway mutations underlying cortical malformations such as focal cortical dysplasia and hemimegalencephaly, and SLC35A2…
- Trial name
- GENEPHY (NCT02890641)
- Testing
- Sampling of blood, frozen resected tissues, and cerebrospinal fluid (CSF)
- Where
- France
- Volunteers
- 450 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Cancer, Therapy-Related
A Longitudinal Photo-Narrative Exploration of Hope During Phase 1/2 Clinical Trials For Pediatric Cancer
The purpose of this study is to find better ways to help support families in their hopes during cancer treatment. Primary Objective To characterize themes related to how patients and parents/caregivers narrate their experience of…
- Trial name
- NCT07444216
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- St. Jude Children's Research Hospital
Major Depressive Disorder (MDD)
Group Therapy for Major Depression: Comparing Expectation-Focused and Reward-Focused Psychotherapy Approaches
Major depressive disorder (MDD) is one of the most common psychiatric conditions and often remains difficult to treat effectively.
- Trial name
- PERSPECT (NCT07388004)
- Testing
- Expectation-Focused Psychotherapeutic Intervention, Reward Enhancement and Activation Therapy
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Philipps University Marburg
Overweight, Overweight and Obesity
Taxi ROADmAP (Realizing Optimization Around Diet And Physical Activity)
The researchers will conduct 'Taxi ROADmAP (Realizing Optimization Around Diet And Physical activity)', which also utilizes MOST, and the same 4 obesity intervention components as in SANOS, but targets the overweight/obesity…
- Conditions
- Overweight, Overweight and Obesity, Overweight or Obesity, Obesity
- Trial name
- NCT05770570
- Testing
- Counseling, Text Messages, Phone calls
- Where
- United States
- Volunteers
- 1,889 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Overweight, Obesity
Consumption of More Ideal Food Options (COMIDA: Consumo de Opciones Más Ideales De Alimentos)
The Mexican Consulate runs a Ventanilla de Salud (VDS) (Health Window) program in fifty locations nationwide. The VDS provides an opportunity to provide health services to members of the Mexican community.
- Trial name
- COMIDA (NCT03851458)
- Testing
- Initial in-person individual diet and exercise counseling (N vs. Y), Thrice weekly diet and exercise text messages (N vs. Y), Weekly telephone support (N vs. Y)
- Where
- United States
- Volunteers
- 1,785 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Self-Harm, Self-harm Behavior
Self-harm and the Prison Environment Mixed Methods Study
Self-harming behaviour is a major problem in UK prisons: the number of self-harm incidents has more than doubled over the past decade. People who self-harm in prison are at greater risk of subsequent death by suicide.
- Conditions
- Self-Harm, Self-harm Behavior, Self-Harm, Deliberate
- Trial name
- SHAPE (NCT06895668)
- Testing
- None (cohort study)
- Volunteers
- 458 people, healthy volunteers welcome
- Sponsor
- King's College London
Athlete Support
Athlete Needs Assessment & Focus Groups
The overall objective of this study is to investigate various physical and mental health needs of collegiate athletes and how they differ in and out of sport.
- Trial name
- NCT06213350
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Drug Resistant Epilepsy
Fluorescence Guided Focal Cortical Dysplasia Surgery
Epilepsy is one of the most common neurological disorders, with one of the highest morbidity rates of all diseases. Despite the development of new anticonvulsant drugs, around a third of patients suffer from drug-resistant…
- Trial name
- FLUOFOCODYS (NCT07657975)
- Testing
- 5-ALA (Gliolan)
- Where
- 2 sites in France
- Volunteers
- 5 people
- Sponsor
- Hospices Civils de Lyon
Management and Leadership in Healthcare
Management and Leadership in Healthcare: Expectations, Conditions, Skills, and Reflections in a Leadership Program
This study follows first- and second-line healthcare managers who take part in an established leadership development program in a Swedish healthcare region.
- Trial name
- NCT07678905
- Testing
- Leadership Development Program
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Kronoberg County Council
Hip Arthroplasty, Total, Knee Arthroplasty, Total
Perceptions of De-implementing Routine Follow-ups After Hip and Knee Arthroplasty
After undergoing total hip or total knee arthroplasty, current guidelines recommend routine follow-up with an X-ray within 3 months and again at 1 year.
- Trial name
- HAKA-QUALI (NCT07041528)
- Where
- Netherlands
- Volunteers
- 90 people
- Sponsor
- Tergooi Medical Center