Clinical trials: Focus of Study
Prostate Cancer
Water Vapor Ablation for Localized Intermediate Risk Prostate Cancer
The purpose of this study is to evaluate the safety and efficacy of the Vanquish Water Vapor Ablation Device ("Vanquish") in treating subjects with Gleason Grade Group 2 (GGG2) localized intermediate-risk prostate cancer.
- Trial name
- VAPOR 2 (NCT05683691)
- Testing
- Vanquish System
- Where
- 25 sites in United States
- Volunteers
- 400 people
- Sponsor
- Francis Medical Inc.
Alpha1-antitrypsin Deficiency, Healthy Volunteers
GLASSIA Infusion Rate Study
The purpose of this study was to generate sufficient safety and tolerability information in support of an increase in the infusion rate of intravenous GLASSIA in the prescribing information from 0.04 to 0.2 mL/kg/min.
- Trial name
- NCT01651351
- Testing
- Alpha1-proteinase inhibitor
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Baxalta now part of Shire
Prostate Cancer
MRI Targeted Focal Laser Thermal Therapy of Biopsy Confirmed Prostate Cancer
The objective of this study is to establish the safety of MRI targeted laser thermal treatment for men with biopsy confirmed early stage low grade single sector prostate cancer.
- Trial name
- NCT00448695
- Testing
- MRI Targeted Focal Thermal Therapy of Prostate Cancer
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University Health Network, Toronto
Uterine Fibroids
MR Guided Focused Ultrasound Surgery in the Treatment of Uterine Fibroids
This is a prospective, nonrandomized, multi-center study to evaluate the safety and effectiveness of ExAblate in the treatment of uterine fibroids.
- Trial name
- NCT00166270
- Testing
- ExAblate 2000
- Where
- 6 sites in United States
- Volunteers
- 70 people
- Sponsor
- InSightec
Breast Reconstruction, Flap Necrosis
a Prospective Study of Surgical Results, Complications and Predictive Values in Chinese Women Breast Reconstruction
This study prospectively evaluates and compares the effectiveness of ICG fluorescence imaging and LSCI in predicting the risk of necrosis following direct-to-implant breast reconstruction.
- Trial name
- BEST (NCT06779019)
- Testing
- LSCI, ICG (Indocyanine Green)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking Union Medical College Hospital
Focal Epilepsy
Anti-Epilepsy Medication Valproate Administered Via ICV Route and Catheters and Pumps for CSF Infusion
This is a non-randomized open-label extension study for subjects having completed protocol DA071976 or CLN100P.01.
- Trial name
- NCT04529954
- Testing
- Valproic Acid delivered to ICV
- Where
- 8 sites in Australia, Israel
- Volunteers
- 20 people
- Sponsor
- Cerebral Therapeutics LLC
Ganglioneuroblastoma, Localized Resectable Neuroblastoma
Induction Therapy Including 131 I-MIBG and Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma Undergoing Stem Cell Transplant, Radiation Therapy, and Maintenance Therapy With Isotretinoin
This pilot clinical trial studies induction therapy followed by iobenguane I 131 and chemotherapy in treating patients with newly diagnosed high-risk neuroblastoma undergoing stem cell transplant, radiation therapy, and…
- Conditions
- Ganglioneuroblastoma, Localized Resectable Neuroblastoma, Localized Unresectable Neuroblastoma, Regional Neuroblastoma
- Trial name
- NCT01175356
- Testing
- 3-Dimensional Conformal Radiation Therapy, Autologous Hematopoietic Stem Cell Transplantation, Busulfan
- Where
- 25 sites in United States
- Volunteers
- 99 people
- Sponsor
- Children's Oncology Group
Kidney Tumor, Renal Benign Neoplasm
Renal Mass Biopsy, PEER, and 99mTc-sestamibi SPECT/CT for Patients With Clinically Localized Renal Tumors
The goal of this clinical trial is to better tell apart whether kidney tumors are benign (not cancer) or malignant (cancer) based on a biopsy or imaging tests and ask patients how they feel about decisions they make about…
- Conditions
- Kidney Tumor, Renal Benign Neoplasm, Renal Malignant Tumor
- Trial name
- BIOPSy (NCT05728957)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Loyola University
Prostate Cancer
Radiation Therapy Followed by Surgery in High-Risk, Localized Carcinoma of the Prostate
The purpose of the study is to assess the safety of four different doses of radiation therapy followed by to surgery to remove prostate tumor.
- Trial name
- NCT00691977
- Testing
- Radiation Therapy followed by prostatectomy
- Where
- United States
- Sponsor
- Virginia Commonwealth University
The Focus of Study is Description of a Very Rare Case
Complete Penile and Testicular Self-amputation: a Very Rare Case
The study is a case report on penile and testicular self-amputation. We didn't assign a drug of intervention. We tried to describe about this rare phenomenon by observation of the presentation and outcome.
- Trial name
- NCT06448741
- Testing
- Replantation of amputated penis
- Where
- Ethiopia
- Volunteers
- 1 people
- Sponsor
- Worabe Comprehensive Specialiazed Hospital
Cancer
OX-40 Protein Expression in the Sentinel Lymph Nodes of Patients With Cancer
RATIONALE: Studying protein expression in sentinel lymph node tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer.
- Trial name
- NCT00900302
- Testing
- protein expression analysis, immunohistochemistry staining method, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- OHSU Knight Cancer Institute
Prostate Cancer
Study of POMELLA™ Extract to Treat Prostate Cancer
This is a randomized, two-arm, placebo controlled trial to evaluate benefit of treatment using POMELLA™ extract on mechanisms known to drive prostate cancer.
- Trial name
- NCT01100866
- Testing
- POMELLA™ (pomegranate extract)
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- Vancouver Coastal Health
Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
Study of Tumor Samples From Patients With Ewing Sarcoma
This laboratory study is looking at tumor samples from patients with Ewing sarcoma. Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and…
- Trial name
- NCT00898053
- Testing
- laboratory biomarker analysis
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Children's Oncology Group
Focus of Study Instead
Afatinib as Cancer Therapy for Exocrine Pancreatic Tumours
Single-agent gemcitabine is currently still regarded as one international standard of care for patients with advanced pancreatic cancer (Burris 1997 [4]).
- Trial name
- ACCEPT (NCT01728818)
- Testing
- Gemcitabine, Afatinib
- Where
- Germany
- Volunteers
- 119 people
- Sponsor
- PD Dr. med. Volker Heinemann
Gastrointestinal Microbiome (Focus), Gastrointestinal Symptoms
The Effect of a Synbiotic on Intestinal Barrier Function and Microbiota Modulation in Middle-aged to Elderly Individuals With Excessive Body Weight
The study is a single-center, randomized, double-blind, placebo-controlled study in middle-aged to elderly adults with excessive body weight. The study includes an 8-week intervention period followed by a 2-week follow-up period.
- Trial name
- myBIOM (NCT07453823)
- Testing
- Synbiotic
- Where
- Ireland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Chr Hansen - part of Novonesis
Migraine
Multimodal Physiotherapy Intervention for People With Migraine
Migraine is one of the most prevalent primary headache disorders worldwide and is associated with substantial impairments in quality of life, work productivity, and psychosocial functioning.
- Trial name
- NCT07671703
- Testing
- Multimodal Treatment Program, Usual Care
- Where
- Germany
- Volunteers
- 195 people
- Sponsor
- Hochschule Osnabruck
Adult Cancer Survivors, Adult Cancer Patients
Holistic Evaluation of Approaches to Long-term Health & Survivorship
This study aims at investigating behaviors of cancer patient regarding complementary and alternative medicine (CAM) with mixed methodology.
- Trial name
- HEALTHS (NCT07745205)
- Testing
- Interventional mixed-methods evaluation of cancer patient's behaviour regarding CAMs (focus groups), Quantitative evaluation of cancer patient's use of CAM's
- Where
- Belgium
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Jules Bordet Institute
Parkinson Disease, Gait, Shuffling
Efficacy of Proprioceptive Focal Stimulation (EQUISTASI) on Gait Parameters in Parkinson. Italian Multicentric Study
It's already known the efficacy of Gait Analysis (GA) on evaluating gait modification on Parkinson's Disease (PD) Patients (1). On the other hand Proprioceptive Focal Stimulation seems be useful in symptoms amelioration in…
- Conditions
- Parkinson Disease, Gait, Shuffling, Effects of Vibration
- Trial name
- PAGE (NCT02641405)
- Testing
- Equistasi, Inactive Equistasi
- Where
- 6 sites in Italy
- Volunteers
- 126 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Liver Cancer
Sirolimus and Bevacizumab in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery
RATIONALE: Sirolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways.
- Trial name
- NCT00467194
- Testing
- Rapamycin, Bevacizumab
- Where
- 2 sites in Singapore
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- National Cancer Centre, Singapore
Drug-Resistant Focal Epilepsy
EASEE® System Pivotal Study for the United States of America
The goal of this clinical trial is to demonstrate the safety and effectiveness of focal cortex stimulation with the EASEE(R) System in a large cohort of subjects with medically refractory focal epilepsy.
- Trial name
- EASEE4US (NCT07301346)
- Testing
- Implantable minimaly invasive brain stimulator
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Precisis US, Inc.