Clinical trials: Folate
Healthy Aging, Aging
An Evaluation of Folic Acid to Improve Endothelial Sensitivity to Shear Stress in Seniors
The purpose of this study is to evaluate if folic acid improves endothelial sensitivity to shear stress in post-menopausal women.
- Conditions
- Healthy Aging, Aging, Menopause
- Trial name
- NCT04016090
- Testing
- Folic Acid
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Montreal Heart Institute
Pregnancy Related
Assesment of Knowledge,Attitude and Practice of Pregnant Women Regarding Iron,Folic Acid and Multivitamins at AlMonshah District.
Anaemia is defined as the lack of functioning red blood cells (RBCs) that leads to a decrease in the ability to carry oxygen causing a lot of complications during life time.
- Trial name
- NCT05477914
- Testing
- questionnaire
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Sohag University
Acute Myocardial Infarction
The Norwegian Vitamin Trial (NORVIT)
The purpose of this study is to examine whether the lowering of blood homocysteine levels by treatment with B vitamins can prevent cardiovascular disease
- Trial name
- NCT00266487
- Testing
- Folic acid, Vitamin B12, Vitamin B6
- Where
- Norway
- Volunteers
- 3,750 people
- Sponsor
- University of Tromso
Atherosclerosis, Vascular Disease
The Effect of Folic Acid on Atherosclerosis, Cognitive Performance and Hearing
The purpose of this study is to determine if folic acid supplementation can slow down atherosclerotic progression, age-related cognitive decline and age-related hearing loss.
- Conditions
- Atherosclerosis, Vascular Disease, Cognitive Decline, Hearing Loss
- Trial name
- NCT00110604
- Testing
- folic acid (0.8 mg)
- Where
- Netherlands
- Volunteers
- 835 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Cervical Cancer
Folate and Protection Against Cervical Cancer
This is a randomised double-blind placebo-controlled trial to see whether giving a low dose of the vitamins folic acid and riboflavin is beneficial to women who have very low grade abnormalities of the cervical cells.
- Trial name
- NCT00220532
- Testing
- Folic acid with riboflavin
- Where
- United Kingdom
- Volunteers
- 180 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Vitamin B-12 Deficiency
THE B-BABIES STUDY: An Observational Study of Group B Vitamins in Preterm Infants
Infancy may be associated with a risk of micronutrient depletion due to the high demands of rapid growth. This is particularly true when preterm birth occurs, as the period before term exhibits the highest rate of bodily growth…
- Trial name
- B-BABIES (NCT07163962)
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Folate Deficiency, Iodine Deficiency
Acceptability and Nutritional Impact of Double-fortified Salt Containing Iodine and Folic Acid - Phase 1
The overarching objective of this two-phase project is to assess the effects of fortifying iodized salt with folic acid on improving women's folate status and thereby reduce the risk of neural tube defects (NTDs), which are…
- Conditions
- Folate Deficiency, Iodine Deficiency, Anemia, Macrocytic, Anemia Deficiency
- Trial name
- DFS-IoFA-1 (NCT05792241)
- Where
- Ethiopia
- Volunteers
- 100 people
- Sponsor
- University of California, Davis
Neoplasm Metastasis, Colorectal Cancer
5-FU, Folinic Acid and Irinotecan (FOLFIRI) Plus Cetuximab Versus FOLFIRI Plus Bevacizumab in First Line Treatment Colorectal Cancer (CRC)
The FIRE-3 trial is a multicenter randomized phase III trial investigating 5-FU, folinic acid and irinotecan (FOLFIRI) plus cetuximab versus FOLFIRI plus bevacizumab in first line treatment of metastatic colorectal cancer.
- Trial name
- NCT00433927
- Testing
- 5-FU, folinic acid, irinotecan
- Where
- Germany
- Volunteers
- 568 people
- Sponsor
- PD Dr. med. Volker Heinemann
Gastric Cancer
A Study of Onartuzumab in Combination With mFOLFOX6 in Participants With Metastatic HER2-Negative and MET-Positive Gastroesophageal Cancer
This randomized, multicenter, double-blind, placebo-controlled study will evaluate the efficacy and safety of onartuzumab (MetMAb) in combination with 5-fluorouracil, folinic Acid, and oxaliplatin (mFOLFOX6) in participants with…
- Trial name
- NCT01662869
- Testing
- 5-Fluoruracil, Folinic acid, Onartuzumab
- Where
- 125 sites in United States, Australia and 22 more
- Volunteers
- 564 people
- Sponsor
- Hoffmann-La Roche
Ovarian Cancer
FR in Stored Plasma
The folate receptor (FR) is a cell over expressed on the surface of certain cancers, this occurs most frequently in ovarian cancers.
- Trial name
- NCT00787514
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Healthy
Bacterially-synthesized Folate Absorption Across the Large Intestine
The purpose of this study is to determine whether folate produced by bacteria that live in our colon can be absorbed in human colon using a stable isotope method.
- Trial name
- NCT02299778
- Testing
- 13C6-p-aminobenzoic acid
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Cervical Cancer, Precancerous Condition
Folic Acid Clinical Trial for the Prevention of Cervical Cancer
RATIONALE: Supplements, such as folic acid, may stop or delay the development of cervical cancer in women infected with human papillomavirus.
- Trial name
- NCT00703196
- Testing
- folic acid
- Where
- United States
- Volunteers
- 368 people
- Sponsor
- University of Alabama at Birmingham
Metastatic Colorectal Cancer
FLOX + Cetuximab (Erbitux®) for Patients With Metastatic Colorectal Cancer and Wild Type K-RAS Tumor
The Nordic FLOX-regime consists of a combination of bolus 5-FU, leukovorin and oxaliplatin (Eloxatin®). Cetuximab (Erbitux®) is an antibody against the epidermal growth factor receptor (EGFR).
- Trial name
- NCT00660582
- Testing
- Cetuximab (Erbitux), Oxaliplatin (Eloxatin) + Fluorouracil + folinic acid
- Where
- 6 sites in Denmark, Norway and 1 more
- Volunteers
- 152 people
- Sponsor
- Per Pfeiffer
Spina Bifida or Spinal Dysraphism
Vitamin B9 Supplementation Recommendations in Rennes CHU
The study objective is to assess the knowledge and the follow-up of vitamin B9 supplementation recommendations for women in the periconceptional period to prevent neural tube closure defects.
- Trial name
- QUALI B9 (NCT04195542)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 1,284 people
- Sponsor
- Rennes University Hospital
Iron Deficiency Anemia, Coronary Artery Disease
Non-Interventional Study of Ferretab® Comp. (Ferrous Fumarate + Folic Acid Prolonged-Release Capsules) Effects in Adult Patients With Iron Deficiency Anemia and Cardiovascular Disease
The goal of this observational study is to learn how well Ferretab® comp. works and how safe it is for adults with iron deficiency anemia and cardiovascular disease who are receiving treatment as part of their usual medical care.
- Conditions
- Iron Deficiency Anemia, Coronary Artery Disease, Heart Failure With Preserved Ejection Fraction (HFPEF)
- Trial name
- PROMETHEUS (NCT07753031)
- Where
- 5 sites in Russia
- Volunteers
- 389 people
- Sponsor
- Alcea
HPV Infection
The Effect of the Association EGCG, Folic Acid and Vitamin B12 in Preventing the Persistence of HPV Infection.
The purpose of the study is to test the effect of the administration of a dietary supplement consisting of epigallocatechin gallate (EGCG), vitamin B12 and folic acid in the treatment of infections with papilloma virus of the…
- Trial name
- NCT06285357
- Testing
- EGCG + folic acid + B12
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Lo.Li.Pharma s.r.l
Covid19
Vitamin D, Omega-3, and Combination Vitamins B, C and Zinc Supplementation for the Treatment and Prevention of COVID-19
The NUTROVID Factorial Trials The purpose of the NUTROVID-Prevent and NUTROVID-Treat Factorial Trials is to determine whether Vitamin B Complex, Vitamin C, and Zinc; Vitamin D; and Omega3, taken at dosages approximating…
- Trial name
- NUTROVID (NCT04828538)
- Testing
- Vitamin D, Omega DHA / EPA, Vitamin C, Vitamin B complex and Zinc Acetate
- Where
- Mexico
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hospital de la Soledad
Epilepsy, Psychiatric or Mood Diseases or Conditions
Does Valproate Increase Levels of Folate Receptor Autoantibodies in Women?
Women who take folate (folic acid) before getting pregnant can lower the risk of giving birth to infant with certain birth defects. However, some medications may affect the action of folate.
- Trial name
- NCT01231646
- Testing
- No intervention
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Northwell Health
Exercise Performance, Fatigue
Vitamin B Complex Improved Exercise Performance and Anti-fatigue
The aim of the present study was to evaluate potential beneficial effects of TTFD® EX PLUS (Prince Pharmaceutical Co., Ltd., Yunlin County, Taiwan) on fatigue and ergogenic functions following physiological challenge.
- Trial name
- NCT05586295
- Testing
- EX plus
- Where
- Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
Pediatric Leukemia, Other Pediatric Cancers
Follow-up Study of Late Effects of Periconceptional Folic Acid in Mothers and Offspring in the Community Intervention Program Population: The Chinese Children and Families Study
Periconceptional folic acid supplements of 400 (Micro) daily prevent neural tube defects (NTD) in offspring. Some data suggest that periconceptional folic acid supplements, folate levels during pregnancy, and/or certain variants…
- Trial name
- NCT01365975
- Where
- United States
- Volunteers
- 1,382 people
- Sponsor
- National Cancer Institute (NCI)