Clinical trials: Folate Deficiency
Hyperhomocysteinemia
The Effects of 8-week Choline, Betaine, and Folic Acid Supplementation on Plasma Homocysteine Concentration During Guanidinoacetic Acid Loading in Young Healthy Volunteers
A methyl-group acceptor such as guanidinoacetic acid (GAA) could induce hyperhomocysteinemia with the effects of GAA expected to be dose-dependent.
- Trial name
- NCT01371357
- Testing
- TEST 1, TEST 2, TEST 3
- Where
- Serbia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Center for Health Sciences, Serbia
Folate Deficiency, Neural Tube Defects
Folic Acid Salt Study (FISFA Zambia)
Question: How effective is fortified iodized salt with folic acid (FISFA) in increasing serum and red blood cell folate in non-lactating, non-pregnant women of reproductive age in the country of Zambia who do not have active food…
- Trial name
- NCT06734611
- Testing
- Fortified Iodized Salt with Folic Acid (FISFA)
- Where
- 2 sites in United States, Zambia
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
HIV Infections
Vitamin B Therapy for Hyperlactatemia
The purpose of this study is to see if vitamin B can treat mild hyperlactatemia (a higher than normal level of lactate in the blood) in patients who take nucleoside reverse transcriptase inhibitors (NRTIs).
- Trial name
- NCT00031057
- Testing
- Thiamine hydrochloride, Riboflavin
- Where
- 3 sites in United States
- Volunteers
- 225 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Nutritional Status, Nutrient Deficiency
Adults Nutrition as a Protective or Health-risk Factor
To obtain up-to-date data on nutrient intakes in adults, a national dietary survey - the EU Menu study will be conducted during 12 consecutive months in 2017/2018, providing data on the consumption of foods and enabling the…
- Conditions
- Nutritional Status, Nutrient Deficiency, Micronutrient Deficiency, Vitamin D Deficiency
- Trial name
- NUTRIHEALTH (NCT03284840)
- Testing
- Assessement of nutritional status, Thyroid size
- Where
- 3 sites in Slovenia
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)
Vitamin A Deficiency, Iron-deficiency
Effect of Household Use of Multiple Micronutrient-fortified Bouillon on Micronutrient Status Among Women and Children in Two Districts in the Northern Region of Ghana
Background: Micronutrient (MN) deficiencies are severe and widespread in West Africa, particularly among young children and women of reproductive age.
- Conditions
- Vitamin A Deficiency, Iron-deficiency, Folate Deficiency, Vitamin B 12 Deficiency
- Trial name
- NCT05178407
- Testing
- Multiple micronutrient-fortified bouillon cube, Control bouillon cube (iodine-only)
- Where
- Ghana
- Volunteers
- 2,372 people
- Sponsor
- University of California, Davis
Deficiency Vitamins
Micronutrient Status During Pregnancy
An adequate micronutrient status during fetal life and infancy is important for optimal development. Dietary practices during pregnancy, lactation and infancy vary among populations and there is today no clear agreement on what…
- Trial name
- NCT03272022
- Volunteers
- 272 people
- Sponsor
- Haukeland University Hospital
HIV Infection, HCV Coinfection
Folinic Acid: Supplementation and Therapy
Patients infected by HIV or HIV-HCV coinfected have higher survival due to the use of HAART, but survival is accompanied by increased morbidity and associated cardiovascular disease (CVD).
- Trial name
- FAST (NCT02810275)
- Testing
- Folinic Acid
- Volunteers
- 69 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Maternal Anemia, Micronutrient Deficiency
MMS, IFA, and MMS+IFA Supplementation in Pregnant Women
This study aims to compare the effectiveness of Multiple Micronutrient Supplementation (MMS), Iron-Folic Acid (IFA) supplementation, and combined MMS+IFA supplementation among pregnant women.
- Conditions
- Maternal Anemia, Micronutrient Deficiency, Pregnancy Outcomes, Maternal Nutrition
- Trial name
- NCT07665957
- Testing
- Multiple Micronutrient Supplementation (MMS), Iron-Folic Acid (IFA)
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Sindh Institute of Child Health and Neonatology
Folate Deficiency, Iodine Deficiency
Acceptability and Nutritional Impact of Double-fortified Salt Containing Iodine and Folic Acid
The overarching objective of this two-phase project is to assess the effects of fortifying iodized salt with folic acid on improving women's folate status.
- Conditions
- Folate Deficiency, Iodine Deficiency, Anemia Macrocytic, Anemia Deficiency
- Trial name
- DFS-IoFA-2 (NCT06223854)
- Testing
- Iodized salt, Experimental: Iodized salt with lower-dose folic acid fortification, Experimental: Iodized salt with higher-dose folic acid fortification
- Where
- Ethiopia
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Folic Acid Deficiency
Folate-Rich Foods Improve Folate Status
This study evaluates the effects of folate-rich foods regarding improvement of folate status compared with folic acid supplement.
- Trial name
- Folatefood (NCT02373033)
- Testing
- Natural food folate, Folic acid, Apple juice
- Where
- Egypt
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Pneumonia, Pneumocystis Carinii, HIV Infections
A Study of Trimetrexate in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS Not Previously Treated for PCP
To evaluate the safety and effectiveness of trimetrexate (TMTX) given at increasing doses along with the leucovorin calcium (LCV) for treating Pneumocystis carinii pneumonia (PCP) in AIDS patients TMTX is an experimental new drug…
- Trial name
- NCT00000998
- Testing
- Trimetrexate glucuronate, Leucovorin calcium
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Hypertension, Hyperhomocysteinemia
CSPPT- Chronic Kidney Diseases Study
The purpose of this trial is to confirm that enalapril maleate and folic acid tablets is more effective in preventing renal function decline among the patients with primary hypertension when compared to enalapril maleate.
- Trial name
- CSPPT-CKD (NCT01871740)
- Testing
- Enalapril maleate and folic acid tablets, Enalapril maleate
- Where
- 2 sites in China
- Sponsor
- Shenzhen Ausa Pharmed Co.,Ltd
Plexus Choroideus, Metabolic Syndrome
Choroid Plexus Dysfunction in Neurological Diseases
Cerebral folate deficiency (CFD), a partially treatable condition defined by a low folate cerebrospinal fluid (CSF) concentration, can be linked to genetic defects of folate metabolism or be secondary to various diseases without…
- Trial name
- PLEXFOLD (NCT06403189)
- Testing
- Biologic samples and MRI
- Where
- 2 sites in France
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Neurodevelopmental Disorders, Autism Spectrum Disorder
Patterns of Neurodevelopmental Disorders
The purpose of this study is to systematically evaluate the results of medical investigations to identify symptom and biological patterns and common etiologies of neurodevelopmental disorders.
- Conditions
- Neurodevelopmental Disorders, Autism Spectrum Disorder, Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infection, Pediatric Acute-Onset Neuropsychiatric Syndrome
- Trial name
- NCT06213090
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Richard Frye