Clinical trials: Follow-Up Study
Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program
CAR-T Long Term Follow Up (LTFU) Study
Per Health Authorities guidelines for gene therapy medicinal products that utilize integrating vectors (e.g. lentiviral vectors), long term safety and efficacy follow up of treated patients is required.
- Trial name
- PAVO (NCT02445222)
- Testing
- Previously treated CAR-T patients
- Where
- 120 sites in United States, Australia and 21 more
- Volunteers
- 1,105 people
- Sponsor
- Novartis Pharmaceuticals
X-Linked Retinitis Pigmentosa
Follow-up Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene
A clinical trial of AAV5-hRKp.RPGR vector for participants with X-linked retinitis pigmentosa (XLRP)
- Trial name
- NCT04794101
- Testing
- Genetic: AAV5-hRKp.RPGR Intermediate Dose, Genetic: AAV5-hRKp.RPGR Low Dose
- Where
- 28 sites in United States, Belgium and 9 more
- Volunteers
- 97 people
- Sponsor
- MeiraGTx Ocular UK Ltd
Rheumatoid Arthritis
Special Investigation in Patients With Rheumatoid Arthritis (HOPEFUL III Study), a Follow-up Survey of Study P12-069
The main objective of this study was to determine the ability to maintain response after discontinuation of adalimumab treatment and the secondary objective was to determine radiographic progression in participants participating…
- Trial name
- NCT01346501
- Volunteers
- 172 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Bronchopulmonary Dysplasia, BPD
Follow-up Study of Safety and Efficacy in Subjects Who Completed PNEUMOSTEM® Phase II (MP-CR-012) Clinical Trial
This is a follow-up study to investigate the long-term safety and efficacy of PNEUMOSTEM® versus placebo, for the treatment of BPD in premature infants.
- Trial name
- NCT04003857
- Testing
- PNEUMOSTEM®, normal saline
- Where
- 2 sites in South Korea
- Volunteers
- 60 people
- Sponsor
- Medipost Co Ltd.
Heart Failure
PRoMOTE Follow-up Observational Study
The purpose of the study is: To evaluate the Heart Failure Risk Status (HFRS) feature performance. To establish the feasibility of remote follow-up in which patient risk triaging is performed by nurse-led review of HFRS feature…
- Trial name
- PRoMOTE FU (NCT03009175)
- Testing
- Implantable Cardiac Defibrillator, Cardiac Resynchronization Therapy Defibrillator/Pacemaker
- Volunteers
- 287 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Osteoarthitis, Arthritis Knee
Post Market Clinical Follow-Up Study for EVOLUTION® NitrX™ Keeled Tibia and EVOLUTION® NitrX™ CS/CR Femur With Cruciate Sacrificing Insert
MicroPort Orthopedics Inc. (MPO) plans to market the EVOLUTION® NitrX™ Non-Porous Keeled Tibia and EVOLUTION® NitrX™ CS/CR Non-Porous Femur with the EVOLUTION® Cruciate Sacrificing (CS) Tibial Insert globally, including in the…
- Conditions
- Osteoarthitis, Arthritis Knee, Joint Diseases, Avascular Necrosis
- Trial name
- NitrX (NCT07391592)
- Testing
- EVOLUTION® NitrX™
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- MicroPort Orthopedics Inc.
Vascular Aneurysm
A Study in Patients with a Descending TAA or PAU Treated with the E-nya Thoracic Stent Graft System
The CONFORM-TAA post-market clinical follow-up study is undertaken to evaluate the prevention of death related to a descending aortic aneurysm or PAU when treated by the E-nya Thoracic Stent Graft System.
- Trial name
- CONFORM-TAA (NCT04381507)
- Testing
- endovascular repair
- Where
- Germany
- Volunteers
- 1 people
- Sponsor
- JOTEC GmbH
Herpes Zoster, Herpes Zoster Vaccine
A Long-term Follow-up Study (ZOE-LTFU) of Two Studies 110390 (ZOSTER-006) and 113077 (ZOSTER-022) to Assess the Efficacy, Safety, and Immunogenicity Persistence of GSK Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine and Assessment of 1 or 2 Additional Doses in Two Subgroups of Older Adults
The purpose of this study was a long-term follow-up of the two studies 110390 and 113077 (ZOSTER-006/022) to assess the efficacy, safety, and immunogenicity persistence of GSK Biologicals' Herpes Zoster subunit (HZ/su) vaccine…
- Trial name
- NCT02723773
- Testing
- Herpes Zoster Vaccine GSK1437173A
- Where
- 161 sites in United States, Australia and 16 more
- Volunteers
- 7,539 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Systolic Left Ventricular Dysfunction
The C-MIC-II Follow-Up Study
The C-MIC System is a medical device used to treat heart failure per the intended purpose which is to treat heart failure by applying an electrical micro-current to the heart.
- Trial name
- C-MIC-II-FU (NCT05189860)
- Testing
- C-MIC system
- Where
- 6 sites in Bosnia and Herzegovina, Croatia and 2 more
- Volunteers
- 31 people
- Sponsor
- Berlin Heals GmbH
Arthritis, Rheumatoid
Long-Term Safety Follow-Up Of Subjects Previously Enrolled In Rheumatoid Arthritis Studies Of CP-690,550
The purpose of this study is to follow the health of subjects who have previously been enrolled in studies of CP-690,550 for treatment of their rheumatoid arthritis.
- Trial name
- NCT00414661
- Testing
- CP-690,550
- Where
- 72 sites in United States, Argentina and 19 more
- Volunteers
- 162 people
- Sponsor
- Pfizer
Dacryocystorhinostomy, Ectropion
PMCF-study Using Novosyn® Quick Suture Material in Ophthalmic Surgery
The aim of this study is to show that the performance of Novosyn® Quick suture material is comparable with standard suture material used in Ophthalmic surgery.
- Conditions
- Dacryocystorhinostomy, Ectropion, Entropion, Ptosis
- Trial name
- OPHTHALNOQ (NCT02761083)
- Testing
- Novosyn® Quick, Vicryl® Rapid
- Where
- Spain
- Sponsor
- Aesculap AG
Malignant Melanoma
A Long Term Follow up Study for Patients Who Previously Took Part in the Phase I Study IMM-101-001
Patients who were previously enrolled in Study IMM-101-001 and who provided informed consent were eligible to participate in this study.
- Trial name
- NCT01559818
- Testing
- IMM-101
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Immodulon Therapeutics Ltd
Dry Eye Syndrome
A Study to Evaluate Safety and Efficacy of rhNGF Eye Solution vs Vehicle in Patients With Moderate to Severe Dry Eye
The objective of this study is to assess the efficacy and safety of rhNGF eye drops at 20 μg/ml concentration administered two or three times daily for 4 weeks in patients with moderate to severe dry eye.
- Trial name
- NCT03982368
- Testing
- rhNGF 20 μg/ml, rhNGF 20 μg/ml + vehicle, Vehicle
- Where
- 12 sites in United States
- Volunteers
- 261 people
- Sponsor
- Dompé Farmaceutici S.p.A
Cat Allergy, Rhinoconjunctivitis
An Optional Two Year Follow Up Study to Study CP005A
Cat allergy is an increasingly prevalent condition affecting 10-15% of patients with allergic rhinoconjunctivitis and/or asthma.
- Trial name
- NCT01604018
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- Circassia Limited
Krabbe Disease
Long-term Follow-up Study to Evaluate Safety and Efficacy of FBX-101 in Krabbe Patients
This is an observational study that will enroll any patients with Krabbe disease that have participated in prior interventional clinical trials involving the administration of FBX-101.
- Trial name
- NCT06308718
- Testing
- FBX-101
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Forge Biologics, Inc
Cervical Degenerative Disc Disorder
Post-Approval Study Protocol for the Simplify Cervical Artificial Disc
This study is intended to demonstrate the 5-year long-term safety and efficacy of the Simplify® Cervical Artificial Disc ("Simplify Disc") in subjects enrolled in the non-randomized Simplify Disc IDE study.
- Trial name
- NCT04630626
- Testing
- Simplify Disc, ACDF
- Where
- 15 sites in United States
- Volunteers
- 145 people
- Sponsor
- NuVasive
Osteoarthritis, Knee, Degenerative Joint Disease of Knee
Post Marketing Clinical Follow up Study to Evaluate the Performance and Safety of ORTHIX PLUS
This trial is a post marketing clinical follow up study, aiming to evaluate the performance and safety of ORTHIX PLUS for pain relief in patients suffering from osteoarthritis or degenerative joint diseases.
- Trial name
- NCT05348525
- Volunteers
- 54 people
- Sponsor
- Yooyoung Pharmaceutical Co., Ltd.
Knee Osteoarthritis
Post Marketing Clinical Follow up Study of HyaleXo
Hyaluronic acid is a polysaccharide naturally present in several human tissues such as cartilage. It is the major constituent of synovial fluid and provides its viscosity and elasticity.
- Trial name
- PMCF (NCT07096050)
- Testing
- HyaleXo
- Where
- Romania
- Volunteers
- 101 people
- Sponsor
- Yooyoung Pharmaceutical Co., Ltd.
Glaucoma, Cataract
Observational Study to Evaluate Long Term Outcomes for Ocular Hypertension and Glaucoma Patients Treated With the SpyGlass Bimatoprost Implant System / IOL Combination
The goal of this clinical trial is to further observe and learn if the SpyGlass Pharma Bimatoprost Implant System / IOL Combination works to treat cataracts and either ocular hypertension or glaucoma.
- Conditions
- Glaucoma, Cataract, Ocular Hypertension
- Trial name
- NCT07154810
- Where
- Honduras
- Volunteers
- 23 people
- Sponsor
- SpyGlass Pharma, Inc.
Osteoarthritis, Knee
A Long Term Follow-up Study of Subjects Who Received ICM-203 or Matching Placebo
This is an observational study of the long term safety and efficacy of ICM-203.
- Trial name
- NCT05752032
- Testing
- ICM-203
- Where
- 2 sites in Australia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- ICM Co. Ltd.
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