Clinical trials: Food Allergy in Children
Allergy;Food, Wheat Allergy
Randomized Controlled Trial for Wheat Oral Immunotherapy
IgE-mediated wheat allergy is a growing allergy problem in children, and affected children can predict with immediate-type allergic reactions to the extent of anaphylactic shock.
- Conditions
- Allergy;Food, Wheat Allergy, Children
- Trial name
- WOIT-RCT (NCT06069492)
- Testing
- Wheat-containing food
- Where
- Hong Kong
- Volunteers
- 72 people
- Sponsor
- Chinese University of Hong Kong
Food Allergy in Children
Rapid Escalation Oral Immunotherapy to Achieve Remission in Children With Cashew Allergy
Children with cashew allergy have no approved treatment and must rely on lifelong avoidance, which is stressful and often fails. Less than 10% outgrow their allergy.
- Trial name
- REACH-Cashew (NCT07868731)
- Testing
- cashew oral immunotherapy
- Volunteers
- 25 people
- Sponsor
- Murdoch Childrens Research Institute
Food Allergy
Assessment of Quality of Life in Food Allergic Children
The purpose of this study is 1. To validate in french quality of life questionnaires for food allergic children 2. To evaluate if the quality of life of food allergic french speaking children aged 0-12 years is affected by their…
- Trial name
- NCT01480427
- Volunteers
- 60 people
- Sponsor
- Jacqueline Wassenberg
Milk Allergy
Swedish Study of Immunotherapy for Milk Allergy in Children
This trial is a two-armed open randomized controlled trial in children aged 5-15 years with challenge proven Immunoglobulin E (IgE)-associated milk allergy.The purpose is to determine if oral immunotherapy with milk can induce…
- Trial name
- SWITCH (NCT03819556)
- Testing
- Milk protein in fresh milk
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Umeå University
Eczema, Egg Allergy
Promoting Tolerance to Peanut in High-Risk Children
This study will evaluate whether early exposure to peanuts promotes tolerance and provides protection from developing peanut allergy in children who are allergic to eggs or who have severe eczema.
- Conditions
- Eczema, Egg Allergy, Food Allergy
- Trial name
- LEAP (NCT00329784)
- Testing
- Peanut Consumption Group
- Where
- United Kingdom
- Volunteers
- 640 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Food Allergy in Children, Food Allergy in Infants
Impact of E-learning on Parental Confidence in Managing Food Allergy
Education and dietary support are integral in managing food allergy in children. The study aim is to analyze the impact of E-learning on parental confidence in managing their child's food allergy.
- Trial name
- NCT04955132
- Testing
- E-learning
- Where
- Lithuania
- Volunteers
- 100 people
- Sponsor
- Vilnius University
IgE Mediated Peanut Allergy
Boiled Peanut Oral Immunotherapy for the Treatment of Peanut Allergy: a Pilot Study
Peanut allergy is increasingly common, especially in countries such as UK and Australia. There is currently no accepted routine clinical therapy to cure peanut allergy.
- Trial name
- BOPI-1 (NCT02149719)
- Testing
- Desensitisation using boiled peanut, Desensitisation using boiled peanut (deferred start)
- Where
- United Kingdom
- Volunteers
- 47 people
- Sponsor
- Imperial College London
Food; Allergy, Anaphylactic Shock, Asthma in Children
Omalizumab in Severe Asthmatics With Food Allergy
A prospective assessment of the impact of Omalizumab in terms of efficacy, safety, and quality of life (FA-QoL) in patients with moderate/severe asthma and history of anaphylaxis to peanut, tree nuts, fish, egg, milk, and/or…
- Trial name
- OSAFA (NCT06316414)
- Testing
- Omalizumab
- Where
- Italy
- Volunteers
- 65 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Food Allergy in Children
Efficacy and Safety of Cashew Nut Oral Immunotherapy in Children
Allergy to nuts (cashew, pistachio, walnut, exotic nuts) is a frequent allergy in children, with a prevalence of up to 4.9% of the population and a low resolution rate (9%).
- Trial name
- CAJESITO2 (NCT05821621)
- Testing
- no intervention
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Central Hospital, Nancy, France
Food Allergy in Children
The Naples Pediatric Food Allergy (NAPFA) Score
Food Allergy (FA) is one of the most expensive allergic disorders in the pediatric age, and affecting up to 10% of children worldwide, it is recognized as a global health problem.
- Trial name
- NAPFA (NCT05707858)
- Testing
- Development of the NAPFA score
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Federico II University
Peanut Allergy
Epicutaneous Immunotherapy in Peanut Allergy in Children
This study aims at showing that Epicutaneous Immunotherapy with peanut proteins is safe and efficacious for desensitizing children with peanut allergy.
- Trial name
- ARACHILD (NCT01197053)
- Testing
- Epicutaneous Immunotherapy
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Child Allergy, Food Allergy
Impact of an Educational Tool on Quality of Life and Anxiety in Parents of Children With Nut Allergy
The number of young children with food allergy, in particular with nut allergy, is increasing worldwide. A diagnosis of nut allergy can cause much anxiety in parents.
- Trial name
- NCT05458882
- Testing
- "living with food allergy" educational booklet
- Where
- Ireland
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Children's Health Ireland
Food Allergy, Oral Immunotherapy for Food Allergy
Slow Multiallergen Oral Immunotherapy in Young Children
The aim is to study whether a multiallergen oral immunotherapy (OIT) strategy with slow up-dosing and low treatment dose against food allergy in young children (0.5-3 years) is safe and effective, a method to cure food allergy…
- Trial name
- InFO (NCT06533462)
- Testing
- Multiallergen powder
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska Institutet
Food Allergy in Children
CBT Group Intervention for Children With Food Allergy and Anxiety
The research will design and evaluate a CBT based intervention to support children aged 11-17 with food allergies. The research on this population has shown that they can experience high levels of anxiety in management of their…
- Trial name
- NCT04770727
- Testing
- CBT workshop
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Cow's Milk Allergy
Free Amino Acid-based Formula to Treat Children Cow's Milk Protein Allergy
It is a study to assess the tolerance to a new commercially available infant formula in children affected by Cow's Milk Allergy.
- Trial name
- NCT02536482
- Testing
- Amix
- Volunteers
- 15 people
- Sponsor
- Edetec Indústria Alimentícia S.A.
Bronchial Asthma, Food Allergy
Effects of Montelukast in Asthmatic Children With and Without Food Allergy
To search the effects of montelukast on the airway inflammation including FEV1%, FEV1%/FVC, the provocholine® (methacoline chloride powder for inhalation) challenge tests, the leukotriene levels in the exhaled breath condensate…
- Conditions
- Bronchial Asthma, Food Allergy, Children
- Trial name
- NCT01618929
- Testing
- Montelukast
- Where
- Turkey (Türkiye)
- Volunteers
- 113 people
- Sponsor
- Hacettepe University
Peanut Allergy
Real World, Open Label, QOL Assessment of Peanut Immunotherapy AR101 in Children and Adolescents
To compare the HRQOL of AR101 characterized oral desensitization immunotherapy (CODIT™) in combination with standard of care (peanut avoidance, education) versus standard of care alone in peanut-allergic subjects aged 4 to 17…
- Trial name
- NCT03703791
- Testing
- AR101
- Where
- 11 sites in Spain
- Volunteers
- 1 people
- Sponsor
- Aimmune Therapeutics, Inc.
Cow's Milk Allergy, Functional Gastrointestinal Disorders
Cow's Milk Allergy and Functional Gastrointestinal Disorders
Cow's milk allergy (CMA) is the most common food allergy in early childhood, with an estimated incidence ranging between 2% and 3% in infants and marginally lower in older children.
- Trial name
- NCT01901380
- Testing
- Extensively hydrolyzed casein formula + LGG
- Where
- Italy
- Volunteers
- 220 people
- Sponsor
- Federico II University
Egg Hypersensitivity
Safety of Nasal Influenza Immunisation in Egg Allergic Children - The SNIFFLE 2 Study
Egg allergy is common in early childhood, affecting at least one in 50 preschool children. Influenza ("'flu") vaccines contain egg protein, as the vaccine is cultured in hen's eggs.
- Trial name
- SNIFFLE-2 (NCT02111512)
- Testing
- Administration of Live attenuated influenza vaccine (LAIV)
- Where
- 29 sites in United Kingdom
- Volunteers
- 779 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Food Allergy
Nutrition in Children With Food Allergy
The investigators aim to asses the effect of dieto-therapy and of nutritional counseling on the nutritional status, body growth and tolerance acquisition in children with cow's milk allergy.
- Trial name
- NCT01583907
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Federico II University