Clinical trials: Food Effect
Obesity, Poor Glycemic Control
The Consumption of Beef on Appetite and Cognitive Function
The purpose of the main study is to determine whether the daily consumption of protein-rich meals containing high quality, lean beef products improves appetite control and cognitive function during a weight maintenance diet.
- Conditions
- Obesity, Poor Glycemic Control, Dietary Interventions
- Trial name
- NCT02614729
- Testing
- Standard Protein-Plant, Even Distribution (SP-PLANT-EVEN), Standard Protein-Beef, Even Distribution (SP-BEEF-EVEN), High Protein-Beef, Even Distribution (HP-BEEF-EVEN)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Healthy Volunteers
A Study to Evaluate the Effect of Food and Proton Pump Inhibitor on the Pharmacokinetics of ZN-A-1041 in Healthy Participants
This study is a phase 1, open-label, randomized, four-period crossover study to evaluate the effect of food and rabeprazole on the ZN-A-1041 tablet formulation in healthy male and female participants.
- Trial name
- NCT07329972
- Testing
- ZN-A-1041 Formulation 1, ZN-A-1041 Formulation 2, Rabeprazole
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Genentech, Inc.
Neurogenic Detrusor Overactivity
Study To Assess The Bioequivalence Under Fed And Fasted Conditions Of The Fesoterodine Beads-In-Capsule SR4 And SR7 Formulations And To Estimate The Bioavailability of SR7 Beads Sprinkled On Apple Sauce Relative To The Beads-In-Capsule SR7 Formulation Administer
Open Label, Single-Dose, Crossover Study To Assess The Bioequivalence Under Fed And Fasted Conditions Of The Fesoterodine Beads-In-Capsule (BIC) SR4 And SR7 Formulations And To Estimate The Bioavailability of SR7 Beads Sprinkled…
- Trial name
- NCT04452838
- Testing
- Fesoterodine BIC SR4 fasted (Treatment A in Part A, Treatment G in Part B), Fesoterodine BIC SR7 fasted (Treatment B in Part A, Treatment H in Part B), Fesoterodine BIC SR7 fed (Treatment C in Part A, Treatment F in Part B)
- Where
- Belgium
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy
A Study Comparing Different Formulations of LY3410738 in Healthy Adult Participants
The main purpose of study is to compare different formulations of LY3410738 under fasting condition by looking at the amount of the study drug, LY3410738, that gets into the blood stream and how long it takes the body to get rid…
- Trial name
- NCT06181084
- Testing
- LY3410738, Esomeprazole
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Healthy
Single and Multiple Ascending Dose Study for NKTR-118 and Cross-over Study to Investigate the Effect of Food for NKTR-118 in Japanese Healthy Subjects
The purpose of this study is to evaluate the safety and tolerability of NKTR-118 with healthy subjects.
- Trial name
- Japan SMAD (NCT01318655)
- Testing
- NKTR-118
- Where
- Japan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Pediatric Obesity
Effect of Food Insulin Index on Metabolic Parameters in Obese Adolescents
The aim of this study was to determine the effect of food insulin index (FII) on metabolic parameters and appetite in obese adolescents with insulin resistance.
- Trial name
- NCT03387293
- Testing
- LGI-LII Breakfast, LGI-HII Breakfast
- Volunteers
- 22 people
- Sponsor
- TC Erciyes University
Healthy Volunteer
A Study to Find Out How Different Forms of BIIB091 is Processed in The Body With and Without Food in Healthy Participants
In this study, researchers will learn how the body processes new tablet forms of BIIB091 when taken with and without food. One new form of BIIB091 is an "extended release" tablet, also known as "ER." This form helps release…
- Trial name
- NCT06640933
- Testing
- BIIB091
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Biogen
Healthy
Phase I 2-Way Crossover Study to Assess Relative BA of Tablet Versus Liquid Suspension and Food Effect on Tablet Formulation
The purpose of this study is to compare the liquid suspension form of AZD 2624 to a tablet form of the same drug. This study will also study the effect of food on the tablet form of the drug.
- Trial name
- NCT00867685
- Testing
- AZD2624
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy Volunteer Study
AZD8566 Food Effect/Microtracer Study
A study designed to look at how the drug AZD8566 is taken up by the body when given with or without food. In some subjects a comparison will be made with a very small labelled microdose given into a vein.
- Trial name
- NCT00866385
- Testing
- AZD8566, AZD8566 IV carbon labelled
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Pharmacokinetics
Relative Bioavailability of ESK-001 Tablet Versus Liquid in Healthy Participants
This is a single-center, in-house, open-label, crossover study in 15 healthy participants.
- Trial name
- NCT05330858
- Testing
- ESK-001, Rabeprazole
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Alumis Inc
Epilepsy
The Tolerability and Effect of Food on the Pharmacokinetics of a Single 800 mg Oral Dose of BIA 2-093
The purpose of this study is to investigate the effect of food on the pharmacokinetics of a single 800 mg oral dose of BIA 2-093 in healthy volunteers.
- Trial name
- NCT02170649
- Testing
- BIA 2-093
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Bial - Portela C S.A.
Overweight
Role of Ultra-processed Foods in Modulating the Effect of Mediterranean Diet
Mediterranean diet is worldwide promoted as one of the healthiest and most sustainable dietary patterns. One of the main pillars of Mediterranean diet is the abundant consumption of plant-based ingredients typically consumed as…
- Trial name
- PROMENADE (NCT06314932)
- Testing
- MD high in UPF, MD low in UPF
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- University of Milan
Food; Allergy, Anaphylactic Shock, Asthma in Children
Omalizumab in Severe Asthmatics With Food Allergy
A prospective assessment of the impact of Omalizumab in terms of efficacy, safety, and quality of life (FA-QoL) in patients with moderate/severe asthma and history of anaphylaxis to peanut, tree nuts, fish, egg, milk, and/or…
- Trial name
- OSAFA (NCT06316414)
- Testing
- Omalizumab
- Where
- Italy
- Volunteers
- 65 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Gut Microbiome
Effects of a Novel Food Product Containing Microbiota Accessible Carbohydrates on the Human Microbiome
This is a randomized, 2-period crossover study aimed at assessing the effect of taking a food supplement containing a blend of microbial accessible carbohydrates on the diversity of the gut microbiome.
- Trial name
- NCT03058575
- Testing
- Dietary MACs, Control
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Access Business Group
Healthy Participants
A Study of the Effects of Food and Cobicistat on Plixorafenib Pharmacokinetics in Healthy Participants.
The primary goal of this phase 1 study is to evaluate the effect of food and cobicistat on the pharmacokinetics of plixorafenib in healthy participants.
- Trial name
- NCT06385119
- Testing
- Plixorafenib, Cobicistat
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Fore Biotherapeutics
Chronic Hepatitis C
First in Human Study of AL-335; Single Dose, Food Effect in Healthy Volunteers; Multiple Doses in Chronic Hepatitis C Genotype 1
This randomized, double-blind, placebo-controlled, 3-part study will assess the safety, tolerability, and pharmacokinetics of orally administered AL-335 in healthy volunteers (HV) and subjects with CHC infection.
- Trial name
- NCT02339207
- Testing
- AL-335
- Where
- 3 sites in France, Georgia and 1 more
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Alios Biopharma Inc.
Cardiovascular Diseases, Apolipoproteins
Functional Yogurt Consumption and Its Effects on the Lipid Profile of Healthy Subjects
The purpose of this study was to assess the effect of the daily intake of yogurts enhanced with Sacha Inchi oil and hybrid palm tree oil on human plasma lipids related to cardiovascular risk factors
- Conditions
- Cardiovascular Diseases, Apolipoproteins, Food Preferences, Low-density-lipoprotein-type
- Trial name
- FYOPO (NCT06574711)
- Testing
- Sacha inchi oil yogurt, Hybrid palm oil yogurt, Control yogurt
- Where
- Colombia
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Javeriana
Healthy
Study to Estimate the Relative Bioavailability Compared to Commercial Extended-release Tablet Formulation and the Effects of Food Or Sprinkling on Applesauce for Fesoterodine Sustained-release Beads-in-capsule Formulations in Healthy Adult Volunteers
The purpose of this study is to evaluate the relative bioavailability of 2 new bead-in-capsule formulations compared to the commercial extended-release formulation (both fed and fasted) and to assess the effect of sprinkling the…
- Trial name
- NCT02160158
- Testing
- Fesoterodine ER (fasted), Fesoterodine SR3 (fasted), Fesoterodine SR3 (fed)
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer
Attention Deficit Hyperactivity Disorder
Safety and Efficacy of Methylphenidate in Children With Attention-deficit Hyperactivity Disorder (ADHD)
This study evaluated the safety and clinical effect of treatment with methylphenidate under different breakfast conditions (minimal breakfast versus standard continental breakfast) in children with Attention-Deficit Hyperactivity…
- Trial name
- NCT00428792
- Testing
- Methylphenidate 20 mg long-acting capsules
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Novartis
Muscle Soreness
Effect of Pistachios on Muscle Recovery
Pistachios are an understudied and often unappreciated functional food. While nuts in general have received somewhat more attention for their nutritional properties from researchers, practitioners and the media, pistachios often…
- Trial name
- NCT03698032
- Testing
- Water, 1.5 oz Pistachios, 3.0 oz Pistachios
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- San Diego State University