Clinical trials: Food Hypersensitivity
Hereditary Angioedema
A Relative Bioavailability Study of Two Formulations of BCX7353
This is an open-label, randomized study to investigate the relative bioavailability of two formulations of BCX7353 and to determine if there is a food effect
- Trial name
- NCT03202784
- Testing
- BCX7353
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- BioCryst Pharmaceuticals
Eosinophilic Esophagitis (EoE)
A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis
This study is researching an experimental drug called dupilumab (called "study drug"). The study is focused on children with active eosinophilic esophagitis (EoE; an inflammatory disease of the esophagus) which impacts feeding…
- Trial name
- EoE-TOTs (NCT07112378)
- Testing
- dupilumab
- Where
- 13 sites in United States
- Volunteers
- 20 people
- Sponsor
- Regeneron Pharmaceuticals
Food Hypersensitivity
Food Allergy Challenge Diagnostic Study
The objective of this study is to correlate various diagnostic measurements taken during an escalating dose oral food challenge to the subject's response.
- Trial name
- NCT02606721
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- ORA, Inc.
Peanut Allergy
Follow-up of the EPITOPE Study to Evaluate Long-term Efficacy and Safety of DBV712 in Young Children
Open-label, follow-up study for subjects who completed the EPITOPE study.
- Trial name
- EPOPEX (NCT03859700)
- Testing
- DBV712 250 mcg
- Where
- 26 sites in United States
- Volunteers
- 304 people
- Sponsor
- DBV Technologies
Cow's Milk Allergy
Extensively Hydrolyzed Infant Formula in Infants and Children With Cow's Milk Allergy
This is a multi-center, randomized, double-blind, placebo-controlled food challenge to be conducted in infants or children with confirmed IgE-mediated cow's milk allergy (CMA), followed by a 7-day open feeding of the experimental…
- Trial name
- NCT04910373
- Testing
- Experimental Extensively Hydrolyzed Formula
- Where
- 4 sites in United States
- Volunteers
- 1 people
- Sponsor
- Abbott Nutrition
Asthma
Single and Multiple Doses of HA115 and Food Effect in Healthy Adult Volunteers
This is a randomized, double-blind, placebo-controlled Phase 1 study of HA115 capsules administered orally to healthy adult volunteers.
- Trial name
- NCT03567694
- Testing
- HA115
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Conjupro Biotherapeutics, Inc.
Allergy, Food Allergy
An Elimination Diet Using a New Amino Acid Based Formula: Immunological and Clinical Effects in Cow's Milk Allergy
The purpose of this study is to evaluate whether a new version of an amino acid based formula improves tolerance to milk in cow's milk allergic infants/young children.
- Trial name
- NCT01109966
- Testing
- Special Medical Food
- Where
- 7 sites in France, Germany and 1 more
- Volunteers
- 34 people
- Sponsor
- Nutricia Research
Cow Milk Allergy
Cow Milk Allergy: Evaluation of the Efficacy of a New Thickened Extensively Hydrolyzed Formula in Infants With Confirmed Cow Milk Allergy
The aim of the study is to assess the hypoallergenicity of a new thickened extensively hydrolyzed formula.
- Trial name
- COMETE (NCT02351531)
- Testing
- Extensively Hydrolyzed formula
- Where
- 3 sites in Belgium, France and 1 more
- Volunteers
- 32 people
- Sponsor
- United Pharmaceuticals
Healthy Volunteers, Atopic Diathesis and Atopic Dermatitis
Single Dose and Multiple Dose Study to Assess Safety and Tolerability of LOU064
This is a 6-part first-in-human study in up to approximately 184 participants. Parts 1 to 5 is in health volunteers and part 6 is in subjects with atopic dermatitis.
- Trial name
- NCT03918980
- Testing
- LOU064
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Allergy
Acceptability and Palatability Study of Paediatric Amino Acid Feed
Product acceptability and palatability data from a minimum of 15 participants are required to submit an application to the Advisory Committee on Borderline Substances (ACBS) and the Health Service Executive (HSE) for Ireland for…
- Trial name
- NCT06547346
- Testing
- Alfamino Junior
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Société des Produits Nestlé (SPN)
Allergy Testing, Peanut Allergies
BÜHLMANN BAT (Basophil Activation Test) in Allergy Diagnosis (Exploratory Pilot Study)
The goal of this exploratory pilot study is to generate early data needed for future validation studies of the automated BÜHLMANN BAT (Basophil activation test) assay.
- Conditions
- Allergy Testing, Peanut Allergies, Venom Allergy, House Dust Mite Allergy
- Trial name
- NCT07596303
- Where
- Germany
- Volunteers
- 38 people
- Sponsor
- Bühlmann Laboratories AG
Peanut Allergy
Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of IGNX001
The goal of this randomized, double-blind, placebo-controlled, single ascending dose clinical trial is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of IGNX001 in peanut-allergic adults and older…
- Trial name
- NCT06331728
- Testing
- IGNX001
- Where
- 4 sites in Australia
- Volunteers
- 32 people
- Sponsor
- IgGenix Australia Pty Ltd
Food Hypersensitivity
Elemental Formula Hypoallergenicity
The primary objective of this clinical trial is to determine whether a new amino acid-based formula is hypoallergenic as defined by the American Academy of Pediatrics (2000), demonstrating that the test formula does not provoke…
- Trial name
- NCT01569776
- Testing
- Amino Acid formula, Commercially available Amino Acid Formula
- Where
- 9 sites in United States
- Volunteers
- 37 people
- Sponsor
- Société des Produits Nestlé (SPN)
Allergy to Cats, Allergic Rhinoconjunctivitis
Effect of holoBLG on Cat Allergic Patients
The aim of the study is to investigate the antigen-unspecific effect of a 3 months supplementation with a food for special medical purposes (FSMP) in form of a lozenge containing beta-lactoglobulin (BLG), iron, retinoic acid…
- Trial name
- NCT05455749
- Testing
- holoBLG
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- Allergy Therapeutics
Hereditary Angioedema
A Study of the Relative Bioavailability of a New Formulation of BCX4161 and the Effect of Food on BCX4161
The purpose of the study is to compare how the body takes up and then eliminates the study drug BCX4161 when it is taken orally as a hard gelatin capsule and as a soft gelatin capsule.
- Trial name
- NCT02125162
- Testing
- BCX4161
- Where
- United Kingdom
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- BioCryst Pharmaceuticals
Healthy Volunteers
Assessement of the Soothing Effect of a Food Supplement on Sensitive and Reactive Skin
The study is aimed to assess the soothing effect of a food supplement composed of Coriander Seed Oil (CSO) in terms of reducing skin redness and skin discomfort (stinging feeling) on sensitive and reactive skin.
- Trial name
- NCT06037291
- Testing
- Coriander Seed Oil
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Seppic
Obesity, Rhinitis
Interventional Testing of Gene-environment Interactions Via the Verifomics Mobile Application
The purpose of this study is to study interactions between genes, lifestyle environmental factors like foods, nutritional supplements and non-invasive medical devices and health factors that can be measured without specialized…
- Conditions
- Obesity, Rhinitis, Rhinitis, Allergic, Respiratory Sounds
- Trial name
- NCT02758990
- Testing
- Vitamin A, Vitamin B6, Vitamin C
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Verifomics LLC
Peanut Allergy
HAL-MPE1 First-in-human
Currently, there is no effective causal treatment for peanut allergy. A chemically modified, aluminium hydroxide adsorbed peanut extract (HAL-MPE1) for subcutaneous administration has been developed.
- Trial name
- HAL-MPE1/0043 (NCT02163018)
- Testing
- HAL-MPE1
- Where
- Denmark
- Volunteers
- 17 people
- Sponsor
- HAL Allergy
Healthy
Drug-drug Interaction and Food-effect Study With GLPG4716 and Midazolam in Healthy Subjects
The purpose of this study is to determine the effect of the administration of multiple doses of GLPG4716 on the amount of midazolam (MDZ) that gets into the blood when the two drugs are administered together compared to when…
- Trial name
- NCT05030857
- Testing
- GLPG4716, Midazolam
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Lakefront Biotherapeutics NV
Infantile Colics, Constipation
Randomized, Blinded, Placebo-Controlled Evaluation of BioAmicus Complete
This is a randomized, single-blind, placebo-controlled study to evaluate the efficacy of the dietary supplement BioAmicus Complete (oral drops; a mixture of 10 strains of lacto- and bifidobacteria) in managing functional…
- Conditions
- Infantile Colics, Constipation, Infantile Diarrhea, Atopic Dermatitis
- Trial name
- NCT07444008
- Testing
- BioAmicus Complete
- Where
- Russia
- Volunteers
- 140 people
- Sponsor
- NovoNatum Ltd