Clinical trials: Food IgE-mediated Allergy, open to volunteers
Cow Milk Allergy, Food Allergy
Effectiveness and Safety of Milk Ladders in Children with IgE-Mediated Cow's Milk Protein Allergy
Cow's milk protein allergy (CMPA) is one of the most common food allergies in early childhood. The first-line treatment of CMPA is the elimination of cow's milk proteins (CMPs) from the child's or maternal diet.
- Trial name
- NCT06664918
- Testing
- oral food challenge (OFC)
- Where
- 2 sites in Poland
- Volunteers
- 92 people
- Sponsor
- Medical University of Warsaw
Immunoglobulin E-Mediated Food Allergy, Immunoglobulin G4-Related Disease
Immunoglobulin G4 and Immunoglobulin E Antibodies in a Population With Adverse Reactions to Foodstuffs-related Symptoms
The aim of this study is to analyze a population with symptoms associated with adverse reactions to foodstuffs (ARFS). To determine the levels of food-specific immunoglobulin G4 (IgG4) and immunoglobulin E (IgE) antibody…
- Conditions
- Immunoglobulin E-Mediated Food Allergy, Immunoglobulin G4-Related Disease, Symptoms and Signs, Adverse Reaction to Food
- Trial name
- NCT05681975
- Testing
- Food-specific Immunoglobulin G4 and/or Immunoglobulin E antibody reactions
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universidad Politecnica de Madrid
Hypersensitivity, Food, Legumes Allergy
Observational Study of IgE-Mediated Leguminous Allergies in a Pediatric Population
Prospective, monocentric, observational study with standard care follow-up during 5 years or until the patient reaches the age of 18.
- Trial name
- FabALL (NCT07811141)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Lille
Cow Milk Allergy, Food Allergy
Clinical Versus Home Introduction of Milk in Children with Non-IgE-mediated Cow's Milk Allergy
There are a lot of parents who believe that their child may not tolerate cow's milk because they develop symptoms such as redness of the skin or they may vomit.
- Trial name
- ENIGMA (NCT05785299)
- Testing
- Cow's milk, Home introduction
- Where
- Netherlands
- Volunteers
- 120 people
- Sponsor
- Martini Hospital Groningen
Fish Allergy, Food Hypersensitivity
FASC: Fish Allergy in Spanish Children - A Study of New Cases of Fish Allergy in Children and Adolescents
Fish allergy is one of the leading causes of food-induced allergic reactions in children, but the clinical presentation and patterns of sensitization vary considerably among patients and geographical regions.
- Conditions
- Fish Allergy, Food Hypersensitivity, IgE-Mediated Food Allergy
- Trial name
- FASC (NCT07727148)
- Volunteers
- 120 people
- Sponsor
- Carmelo Escudero
IgE-Mediated Cow Milk Allergy
Evaluation of the Tolerance of a New Formula Based on Hydrolyzed Rice Proteins in Children With Cow's Milk Allergy
The goal of this clinical trial is to see if a new formula based on hydrolysed rice proteins (Rice formula) is well tolerated by infants and young children with cow's milk allergy.
- Trial name
- NCT07197814
- Testing
- Rice formula (New formula based on hydrolysed rice proteins)
- Where
- Italy
- Volunteers
- 29 people
- Sponsor
- Health and Happiness Research Limited
Food Allergy, Egg Allergy
Efficacy and Safety of Egg Ladders in Children With IgE-Mediated Hen's Egg Protein Allergy
Hen's Egg Allergy is one of the most common food allergies in early childhood. The first-line treatment is the elimination of hen's egg proteins from the child's or maternal diet.
- Conditions
- Food Allergy, Egg Allergy, Hen Egg Allergy
- Trial name
- NCT07040111
- Testing
- oral food challenge (OFC)
- Where
- 2 sites in Poland
- Volunteers
- 94 people
- Sponsor
- Medical University of Warsaw
Milk Allergy
Performance of the Basophil Activation Test in the Diagnosis of IgE-mediated Cow's Milk Allergy in Infants and Evaluation of Hydrolysate Allergenicity.
The goal of this clinical trial is to investigate if the basophil activation test (BAT) represents a safer, faster, and more cost-effective diagnostic modality than the state-of-the art diagnostic work-up (specifik IgE and oral…
- Trial name
- MilkBAT (NCT07900594)
- Testing
- Basophil activation test, quality of life questionnaire
- Volunteers
- 100 people
- Sponsor
- Odense University Hospital
Food Allergy, Cow's Milk Protein Allergy
GOAt Milk Formula-based Ladder Versus Cow's Milk Ladder
Children with immunoglobulin E (IgE)-mediated cow's milk allergy (CMA) who react to small amounts of baked cow's milk may require prolonged elimination.
- Conditions
- Food Allergy, Cow's Milk Protein Allergy, Cow's Milk Allergy
- Trial name
- GOAL (NCT07795957)
- Testing
- oral food challenge (OFC)
- Where
- 2 sites in Poland
- Volunteers
- 92 people
- Sponsor
- Medical University of Warsaw
IgE-Mediated Food Allergy, Peanut Allergy
A 52-week Study of Remibrutinib in IgE-mediated Food Allergy
The purpose of this Phase III study is to evaluate the clinical efficacy and safety of remibrutinib in participants with peanut, or cow's milk ("milk", cooked and uncooked) or hen's egg ("egg", cooked and uncooked) immunoglobulin…
- Conditions
- IgE-Mediated Food Allergy, Peanut Allergy, Cow Milk Allergy, Egg Allergy
- Trial name
- NCT07768371
- Testing
- Remibrutinib
- Where
- 18 sites in United States
- Volunteers
- 576 people
- Sponsor
- Novartis Pharmaceuticals
Food Protein Induced Enterocolitis Syndrome (FPIES)
A Multicentre French Prospective Study of Children With Food Protein Induced Enterocolitis Syndrome in Its Acute Form
Food protein induced enterocolitis syndrome (FPIES), is a non-IgE mediated food allergy (FA) which seems to expand, and occurring in infancy. This disease is usually unknown by clinicians.
- Trial name
- SEIPA-FPIES (NCT05528900)
- Testing
- allergy test
- Where
- 19 sites in France
- Volunteers
- 600 people
- Sponsor
- Fondation Lenval
Anaphylactic Reaction, Anaphylaxis
Steroid Use in Treatment of Allergic Reactions to Food
In this study, the investigators want to find out whether a specific medication commonly used for severe allergic reactions is really necessary.
- Conditions
- Anaphylactic Reaction, Anaphylaxis, Allergy in Children, IgE Mediated Food Allergy
- Trial name
- SAFARI (NCT07341776)
- Testing
- Antihistamines, Systemic corticosteroids, Adrenaline (rescue medication)
- Where
- 2 sites in Switzerland
- Volunteers
- 160 people
- Sponsor
- Johannes Trueck
Food Hypersensitivity, Shellfish Allergy
Recombinant Tropomyosin- and Hemocyanin-Specific IgE in Children With Suspected Shrimp Allergy
This study will evaluate whether blood tests that measure IgE antibodies to two shrimp proteins, tropomyosin and hemocyanin, can help diagnose shrimp allergy in children.
- Trial name
- NCT07501325
- Testing
- Oral Food Challenge (OFC), Skin Prick Test, Recombinant Tropomyosin- and Hemocyanin-Specific IgE Measurement
- Where
- Vietnam
- Volunteers
- 129 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Non IgE Mediated Food Allergy, Food Protein-Induced Enteropathy
Non-Immunoglobulin E-mediated Food Allergies in Children
Non-IgE-mediated gastrointestinal food allergies (non-IgE-GIFA) are an evolving web of clinical conditions characterized by subacute and/or chronic symptoms and include food protein-induced enterocolitis syndrome (FPIES), food…
- Conditions
- Non IgE Mediated Food Allergy, Food Protein-Induced Enteropathy, Food Protein-Induced Proctocolitis, Food Protein-Induced Enterocolitis Syndrome
- Trial name
- NIGEFA (NCT04462978)
- Testing
- Non IgE-mediated food allergy
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Federico II University