Clinical trials: Food Labeling
Dietary Fats, Pharmacokinetics
The Effect of Food (High Fat and Low Fat Breakfast) on the Pharmacokinetics of Regorafenib
An open label, three way crossover study to determine the effect of a high fat breakfast or a low fat breakfast on the pharmacokinetics of a single dose of regorafenib.
- Trial name
- NCT01002378
- Testing
- Regorafenib (Stivarga, BAY73-4506)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bayer
Healthy
This Study Will Assess the Safety and Tolerability of AZD8418 After Single Increasing Oral Doses
The main purpose of this study is to assess the safety and tolerability of AZD8418 after single increasing oral doses. Another purpose of this study is to evaluate the pharmacokinetics (also called PK - how the study drug enters…
- Trial name
- NCT01027234
- Testing
- AZD8418
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Formulation Bridging, Food Effect
A Formulation Bridging and Food Effect Study of PBI-200 in Healthy Volunteers
This is a single-dose, two-part, crossover formulation bridging and food effect study to assess the effect of formulation and food on the absorption and bioavailability of PBI-200 in normal, healthy volunteers.
- Trial name
- NCT05690932
- Testing
- PBI-200 Tablet, PBI-200 Capsule, PBI-200 Suspension
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Pyramid Biosciences
Healthy Volunteer
Study to Estimate the Pharmacokinetics, Bioavailability and Effect of Food on Single Dose Modified-release Lersivirine 500 mg in Healthy Subjects
The purpose of this study is to estimate the pharmacokinetics (PK) of 3 different modified-release formulations of lersivirine and compare it to the PK of the immediate-release tablet.
- Trial name
- NCT01603485
- Testing
- Lersivirine Immediate-Release (fasted), Lersivirine Modified-Release #1 (fasted), Lersivirine Modified-Release #2 (fasted)
- Where
- Belgium
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy Participants
A Study to Evaluate Pharmacokinetics (PK) of Etrumadenant Tablet and Capsule Formulations in Healthy Adult Participants
This study will compare the pharmacokinetics (PK) effect of single-dose etrumadenant tablet and capsule formulations in fasted conditions. The effect of food on single-dose PK of tablet formulation will also be assessed.
- Trial name
- NCT05277012
- Testing
- Etrumadenant
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Arcus Biosciences, Inc.
Healthy Participants
A Study of the Effects of Food and Cobicistat on Plixorafenib Pharmacokinetics in Healthy Participants.
The primary goal of this phase 1 study is to evaluate the effect of food and cobicistat on the pharmacokinetics of plixorafenib in healthy participants.
- Trial name
- NCT06385119
- Testing
- Plixorafenib, Cobicistat
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Fore Biotherapeutics
Healthy
Bioequivalence Study of Telmisartan Between Telmisartan 80 mg/Amlodipine 5 mg/Hydrochlorothiazide 12.5 mg (T80/A5/H12.5 mg) Fixed-dose Combination (FDC) Tablet and T80/H12.5 mg Tab and A5 mg (Encap A2.5 mg Tab x2) Concomitant Use
To investigate the steady state pharmacokinetics of different formulation of Telmisartan, Amlodipine, and Hydrochlorothiazide (HCTZ).
- Trial name
- NCT02129192
- Testing
- Amlodipine 5mg capsule, T80/H12.5 mg FDC tablet, T80/A5/H12.5 mg FDC tablet
- Where
- Japan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Oral Bioavailability of GLPG0555 in Different Solid Formulations
The purpose of the study is to compare the pharmacokinetics of a solid capsule formulation of GLPG0555 with a nanosuspension, and to assess safety and tolerability of a single dose of GLPG0555.
- Trial name
- NCT01278095
- Testing
- GLPG0555 solid dispersion, GLPG0555 nanosuspension
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Lakefront Biotherapeutics NV
Healthy
A Study of Bedaquiline 100 Milligram (mg) Tablets Administered as Different Test Formulations Compared to the Commercial Tablet Formulation (F001) in Healthy Adult Participants
The purpose of this study is to assess the rate and extent of absorption of bedaquiline following administration of a single oral dose of 100 milligram (mg) equivalent (1*100 mg) given as different test tablet formulations…
- Trial name
- NCT04087759
- Testing
- Bedaquiline (Test formulation), Bedaquiline (Reference formulation)
- Where
- Belgium
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Healthy
A Study of the Effect of Food on Pirtobrutinib (LOXO-305) in Healthy Participants
The main purpose of this study is to conduct blood tests to measure how much pirtobrutinib (LOXO-305) is in the bloodstream and how the body handles and eliminates pirtobrutinib (LOXO-305) after meals and on an empty stomach.
- Trial name
- NCT06180980
- Testing
- Pirtobrutinib
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Healthy Volunteer
Study Evaluating the Effects of Food, Cytochrome P450 Inhibition and Induction on the Pharmacokinetics of CC-122
This is a phase 1 open-label 4-part study to evaluate the effect of food, cytochrome P450 inhibition and induction on the pharmacokinetics of CC 122 in healthy adult subjects. Approximately 81 subjects will be enrolled.
- Trial name
- NCT03340662
- Testing
- CC-122, Itraconazole, Fluvoxamine
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Celgene
Healthy Volunteers
To Evaluate Food Effect on the Pharmacokinetics of Rebamipide in Healthy Volunteers
This is a randomized, open label, single dose, crossover study to evaluate the food effect on the pharmacokinetics after single oral dose of "rebamipide SR 150 mg" in healthy adult volunteers.
- Trial name
- NCT04150146
- Testing
- Rebamipide SR 150mg after high-fat meal, Rebamipide SR 150mg under fasting condition
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Korea Otsuka Pharmaceutical Co., Ltd.
Healthy Subjects
Levoketoconazole Food Effect Study in Healthy Subjects
This is a phase I, randomized, open-label, single-dose, two-period, two-sequence crossover study in healthy male and female subjects to evaluate the effect of food on the PK of levoketoconazole.
- Trial name
- NCT03768388
- Testing
- levoketoconazole
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cortendo AB
Diet, Healthy
Testing Ultraprocessed Food Labels in Chile
The goal of this experiment is to examine the effects of a warning label signaling that a product is ultraprocessed among a sample of Chilean parents.
- Trial name
- NCT06842680
- Testing
- Control, Ultraprocessed warning label
- Where
- United States
- Volunteers
- 3,645 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Healthy
A Study Investigating Tablet Formulations of Lu AF11167 in Healthy Subjects
The purpose of this study is to investigate the extent to which Lu AF11167 enters the bloodstream following tablet intake and the influence of food on uptake in healthy men and women
- Trial name
- NCT04104503
- Testing
- Lu AF11167, [14C]-Lu AF11167, Lu AF11167 MR tablet prototype formulation selected from part A or 1 mg modified release tablet (reference formulation)
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Health Subjects
A Study to Evaluate the Food Effects on Pharmacokinetics of SY-5007 Tablets in Healthy Subjects
This study is a single-center, randomized, open-label, single-dose, two-period, two-treatment crossover trial aimed at evaluating the pharmacokinetic (PK) profiles and safety of SY-5007 tablets administered orally to healthy…
- Trial name
- NCT06325761
- Testing
- SY-5007
- Where
- China
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Shouyao Holdings (Beijing) Co. LTD
Obesity
Does Food Labeling Influence Long-term Food Intake and Eating-related Variables in Women?
Weight management is a critical issue in developed countries where the prevalence of obesity is always increasing. While the mismatch of energy intake and energy expenditure is recognized as a leading cause of obesity, knowledge…
- Trial name
- MENU (NCT01604954)
- Testing
- Nutrient-label, Calorie-label, No label
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Laval University
Healthy
Relative Oral Bioavailability of BI 44847 as Suspension Compared to Tablet and the Influence of Food Anf of BI 44847 as Solution Compared to Tablet in Healthy Male Volunteers
Study to investigate the relative oral bioavailability of 400 mg BI 44847 as suspension vs. 400 mg BI 44847 as tablet, to investigate a food effect on the 400 mg tablet pharmacokinetic (PK) and to investigate relative oral…
- Trial name
- NCT02211937
- Testing
- BI 44847 solution, low dose, BI 44847 suspension, high dose, BI 44847 tablet, low dose
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Interaction Drug Food
Drug Interactions Trial of Methoxyethyl Etomidate Hydrochloride
Sixty-eight healthy subjects were divided into three sequences: A, B and C. The effects of CYP2C19 inhibitor fluconazole and inducer rifampicin on ET-26-HCl injection were evaluated, and the effects of ET-26-HCl injection on…
- Trial name
- NCT06822166
- Testing
- rifampicin, Fluconazole, Omeprazole
- Where
- China
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ahon Pharmaceutical Co., Ltd.
Purpura, Thrombocytopaenic, Idiopathic
Relative Bioavailibilty for Pediatric Powder for Suspension (PfOS) Formulation and Food Effect
This is a randomized, open-label, five-period, balanced crossover study conducted in approximately 40 healthy adult subjects enrolled at one study center in the USA.
- Trial name
- NCT01072162
- Testing
- Eltrombopag
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline