Clinical trials: Food Labeling
Healthy
Alternative 10 mg/mL Liquid Formulation of ACY 1215 (Ricolinostat) in Healthy Subjects
This study will be an open-label, randomized, single dose, 3-period crossover PK study. This study will comprise 3 treatment periods with a 4-day washout between periods.
- Trial name
- NCT02088398
- Testing
- ACY-1215
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Acetylon Pharmaceuticals Incorporated
Healthy
A Study of Food Effect on Tersolisib (LY4064809) in Healthy Participants
The main purpose of this study is to measure how food affects the amount of tersolisib that gets into the bloodstream. Each participant will receive two single oral doses of tersolisib, one under fasted conditions and one with…
- Trial name
- NCT07662798
- Testing
- Tersolisib, High-fat Meal, Low-fat Meal
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Alcohol Use Disorder, Supplementation
Administration of Fiber as a Dietary Supplement to Improve the Management of Alcohol Withdrawal
The goal of this clinical trial is to demonstrate that a fiber-enriched diet (with a high proportion of inulin and pectin) combined with standard care can reduce intestinal permeability in patients with alcohol use disorder (AUD)…
- Conditions
- Alcohol Use Disorder, Supplementation, Intestinal Permeability
- Trial name
- FIB-ALC (NCT07371286)
- Testing
- Administration of fibers as a dietary supplement
- Volunteers
- 138 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Healthy Volunteers
Evaluation of the Relative Bioavailability and Food Effect of GDC-9545 in Healthy Females of Non-Childbearing Potential
This study will be an open-label, randomized, three-period, six-sequence crossover study of GDC-9545 administered to healthy females of non-childbearing potential to determine the relative bioavailability of the Phase 3 capsule…
- Trial name
- NCT04274075
- Testing
- GDC-9545 Tablet, Fasted: Treatment A, GDC-9545 Capsule, Fasted: Treatment B, GDC-9545 Capsule, Fed: Treatment C
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Genentech, Inc.
Muscular Atrophy, Spinal
Bioavailability and Bioequivalence of Two Risdiplam Tablets in Healthy Participants
The study is a randomized, single oral dose, crossover study in up to three parts to investigate the relative bioavailability and bioequivalence of two different formulations of risdiplam 5 mg (dispersible tablets) versus the…
- Trial name
- NCT04718181
- Testing
- risdiplam, omeprazole
- Where
- 4 sites in United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Healthy
Phase 1 Single Ascending Dose Study to Evaluate Safety, Tolerability and Pharmacokinetics of KBP-5074
This single ascending dose (SAD) study in healthy subjects will evaluate the safety, tolerability and pharmacokinetics of KBP-5074.
- Trial name
- NCT02228733
- Testing
- KBP-5074
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- KBP Biosciences
Health, Subjective, Food-drug Interaction
ABSK091 Food Effect Study in Healthy Subjects
In this study, a single oral dose of the tablet formulation administered under fed conditions will be compared to administration under fasted conditions to assess the effects of a high-fat meal on the rate and extent of…
- Trial name
- NCT05533788
- Testing
- ABSK091 tablet
- Where
- Taiwan
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Abbisko Therapeutics Co, Ltd
Depressive Disorder and Anxiety Disorders
Relative Bioavailability and Food Effect Study for GSK163090 in Healthy Male and Female Volunteers
The study will consist of a screening period, 3 treatment periods and a post-treatment follow-up. In each of the 3 treatment periods, subjects will receive a single oral dose of GSK163090 in the fed or fasted state, followed by a…
- Trial name
- NCT00536679
- Testing
- GSK163090 capsule, fasted, GSK163090 Tablet, fasted, GSK163090 Tablet, fed
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Advanced Solid Tumor
Food Effect on Pharmacokinetics and Safety of DHP107 (Liporaxel®) FEEL Study
To evaluate the food effect on pharmacokinetics of DHP107 in patients with advanced solid tumors.
- Trial name
- FEEL (NCT04675528)
- Testing
- DHP107(Oral paclitaxel)
- Where
- 5 sites in Hungary
- Volunteers
- 25 people
- Sponsor
- Daehwa Pharmaceutical Co., Ltd.
IgA Nephropathy, Paroxysmal Nocturnal Hemoglobinuria
A Clinical Study to Evaluate the Effect of Food on the Pharmacokinetic Profiles of HRS-5965 Capsules in Healthy Subjects
The study is being conducted to evaluate the effect of food on pharmacokinetics of HRS-5965 capsules after oral administration.
- Trial name
- NCT07035665
- Testing
- HRS-5965 Capsules
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Chengdu Suncadia Medicine Co., Ltd.
Healthy
Relative Bioavailability and Impact of Rabeprazole for PF-07799933, Food-Effect for PF-07799933 and PF-07799544
The purpose of this study is to evaluate the relative bioavailability (rBA) of the Form 2 film-coated tablet of PF-07799933 intended for use in future studies compared to the current Form 1 tablet of PF-07799933 used in Phase 1…
- Trial name
- NCT07563894
- Testing
- PF-07799933 tablets with PF-07799544 fasted, PF-07799933 film-coated tablets with PF-07799544 fasted, PF-07799933 film-coated tablets with PF-07799544 fed
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy Volunteer
Effect of Food, Rabeprazole, Methotrexate and Formulation on the Pharmacokinetics (PK) of GDC-0853 and the Effect of GDC-0853 on the PK of Methotrexate in Healthy Subjects
This study is a Phase I, single center, randomized (Parts 1 and 2 only), open-label, 3 part study. Parts 1 and 2 are 2-way crossover, with 1-fixed sequence, 3-period designs to investigate the effect of formulation, food and…
- Trial name
- QCL117578 (NCT02699710)
- Testing
- Folic Acid, GDC-0853, Methotrexate
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Genentech, Inc.
Hypertension
Attitudes and Understanding of Sodium Claims on Food Labels
Sodium-related claims on food labels should help people find lower sodium food choices; however consumer attitudes and understanding of such claims are unknown.
- Trial name
- NCT01764724
- Testing
- Mock package questionnaire
- Where
- Canada
- Volunteers
- 987 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy Volunteers
Investigate Bioequivalence of Alpelisib Granule and Film-coated Tablet Formulation and the Food Effect of Alpelisib Granule Formulation in Adult Healthy Volunteers
The purpose of this study is to assess bioequivalence of the granule formulation of alpelisib as compared to the film-coated tablet formulation in healthy volunteers in the fed state.
- Trial name
- NCT05195892
- Testing
- Treatment A, Treatment B, Treatment C
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Myelodysplastic Syndromes
A Study of Oral Clofarabine in Adult Patients With Myelodysplastic Syndromes (MDS)
This study will be used to determine the maximum tolerated dose of oral clofarabine when administered daily for 14 consecutive days repeated every 21 days.
- Trial name
- NCT00750334
- Testing
- clofarabine
- Where
- 3 sites in United States
- Volunteers
- 2 people
- Sponsor
- Genzyme, a Sanofi Company
Chronic Hepatitis B
A Study to Assess the Relative Bioavailability and Food Effect of ABI-H2158 in Healthy Adults
This study is designed to assess the relative bioavailability of ABI-H2158 tablets (Test Formulation) compared to ABI-H2158 tablets (Reference Formulation).
- Trial name
- NCT04083716
- Testing
- ABI-H2158 Reference Formulation, ABI-H2158 Test Formulation
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Assembly Biosciences
Healthy
Study of Evaluation of Cavir Tab. 0.5mg With Food Effect on Pharmacokinetics and Safety
In this clinical trial, the investigator will clarify the difference in pharmacokinetics between the group single dose Cavir Tab. 0.5mg and single dose Cavir Tab. 0.5mg with high fatty meal for healthy adult volunteer.
- Trial name
- NCT02586363
- Testing
- Baraclude Tab. 0.5mg, fasting, Cavir Tab. 0.5mg, fasting, Cavir Tab. 0.5mg, high fatty meal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Seoul St. Mary's Hospital
Hepatitis C
TMC435-TiDP16-C116 - Relative Bioavailability and Food Effect Study
The purpose of this study is to compare absorption of TMC435 formulated as 2 different types of capsules. After that, the absorption of one chosen TMC435 capsule will be compared when taken under fasting conditions or together…
- Trial name
- NCT01308606
- Testing
- TMC435 HPMC capsule, TMC435 HPMC or gelatin capsule, TMC435 gelatin capsule
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Tibotec Pharmaceuticals, Ireland
Healthy
A Study in Healthy Men to Test How Different Doses of BI 3000202 Are Tolerated and How Food Influences the Amount of BI 3000202 in the Blood
The single rising dose (SRD) part of the trial investigates safety, tolerability, and pharmacokinetics of BI 3000202. The food effect (FE) part is conducted to assess the effect of food on the relative bioavailability of the BI…
- Trial name
- NCT05945888
- Testing
- BI 3000202
- Where
- Germany
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Hypertension
Evaluation of an Antihypertensive Food Supplement Based on Aqueous Extract From Annona Muricata Sheets
The AM-HTN trial aim to investigate the effects of a tablet based on aqueous extracts of Annona muricata as add-on therapy in a hypertensive population.
- Trial name
- AM-HTN (NCT03909945)
- Testing
- Annona muricata
- Where
- Cameroon
- Volunteers
- 21 people
- Sponsor
- Yaounde Central Hospital