Clinical trials: Food Reward
Healthy, Brain Insulin Sensitivity
Long-Term Effects of Walnut Consumption on Brain Function
Rationale: Healthy foods, including mixed nuts, may improve brain function, which is essential for cognitive and metabolic health, and may contribute to improved food intake regulation.
- Conditions
- Healthy, Brain Insulin Sensitivity, Cerebral Blood Flow, Brain Vascular Function
- Trial name
- WalBrain (NCT07422220)
- Testing
- Walnuts
- Where
- Netherlands
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Weight Loss, Appetitive Behavior
Investigating the Early Markers of Weight Loss
The study will include 30 women randomized in two distinct groups: G1: Slow weight loss and G2: Rapid weight loss . The total duration of the program will be different for each group, being over 20 and 10 weeks for G1 and G2…
- Conditions
- Weight Loss, Appetitive Behavior, Obesity
- Trial name
- NCT04866875
- Testing
- dieting
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Weight Gain, Food Habits
Relation of Consummatory and Anticipatory Food Reward to Obesity
Obesity is associated with increased risk for mortality, atherosclerotic cerebrovascular disease, coronary heart disease, colorectal cancer, hyperlipidemia, hypertension, gallbladder disease, and diabetes mellitus, resulting in…
- Trial name
- NCT01807572
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Obesity, Body Weight
The Effect of Alcohol on Food Reward
Rationale It has been shown in several studies that alcohol increases subsequent food intake. However, moderate alcohol consumption has no clear effects on hunger and satiety hormones.
- Trial name
- NCT01738906
- Testing
- Orange juice, maltodextrin, Vodka
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Henk FJ Hendriks
Appetite and General Nutritional Disorders
Protein Quality on Appetite Control, Reward-driven Eating, & Subsequent Food Intake
To determine whether the consumption of a beef-rich lunch improves appetite control, satiety, and energy intake regulation while reducing food reward and food cravings compared to the consumption of a soy-rich lunch when matched…
- Trial name
- NCT02285907
- Testing
- Macronutrient and Fiber Matched BEEF, Macronutrient and Fiber Matched SOY, Serving Size Matched BEEF
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Binge Eating
Food and the Brain
The proposed study will examine the role of reward and emotion in women with and without a history of binge eating. It is important to understand how the brain responds to reward and emotion in binge eating in order to identify…
- Trial name
- NCT02743000
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Stanford University
Metabolic Diseases
The Effect of Processing on Food Reward
The minimally processed diets of our ancestors have been rapidly replaced by UPFs driving poor diet to become the leading risk factor for preventable death globally.
- Trial name
- PFR (NCT06017986)
- Testing
- Ultra-processed food - Picture Set Meal, Minimally Processed Food - Picture Set Meal
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Children's Nutrition Intake
The Nutritional Effect of Parental Use of Food as a Reward
Control rules are common parental practices that use food as reward to encourage children to conduct parents' preferred behaviors.
- Trial name
- NCT02354157
- Testing
- no intervention
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- McGill University
Cirrhosis, Food Preferences
Feeding Behavior and Taste Sensitivity Before and After Liver or Renal Transplantation
This study evaluates the influence of the taste sensitivity, of food preferences and of the reward system on the energetic balance before and after liver transplantation in cirrhotic patients and after kidney transplantation in…
- Conditions
- Cirrhosis, Food Preferences, Taste Disorders, Protein-Energy Malnutrition
- Trial name
- GREFFE (NCT02931812)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Burgundy
Food Addiction, Obesity, fMRI, Decision-making, Motivational Interviewing
FMRI of Dietary Decision-making in Food Addicted Participants Compared to Non-food Addicted Participants
Why in some situations can words soothe our cravings? This research proposal will test the power of self-generated reasons for behavioural change in food addiction, which concerns about three out of ten persons and causes major…
- Trial name
- MOTIVFOOD (NCT05101863)
- Testing
- Motivational interviewing
- Where
- France
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Olfaction, Diet
The Effects of Acute Caloric Deprivation on Odour Identification and Food Reward
The purpose of this study is to determine how the modality of energy depletion can differently impact appetite hormones, ad libitum food intake, food hedonics, and olfaction.
- Conditions
- Olfaction, Diet, Exercise, Energy Depletion
- Trial name
- DEXDER (NCT02653378)
- Testing
- DIET, EX
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Healthy Normal Weight
Meal Texture and Satiety
The aim of the present study is to compare the nutritional compensation between iso-caloric meals of various textures (liquid vs solid) in health young adults.
- Trial name
- FEED (NCT04041752)
- Testing
- SOLID, LIQUID_P, LIQUID_L
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Circadian Rhythm, Energy Balance
Timing and Resistance Exercise: Impact on Eating and Metabolism
Exercise timing (morning or evening) for optimal weight control is a research topic urgently addressed by scholars in the relevant field.
- Conditions
- Circadian Rhythm, Energy Balance, Appetitive Behavior, Food Reward
- Trial name
- NCT06549322
- Testing
- The exercise in morning, The exercise in evening
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Healthy, Food Reward
The Role of Consumption and Anticipation in Dopamine Release to Food Reward
This study aims to disentangle the relative contribution of the anticipatory (food images) versus consummatory (food administration) component of dopamine release to food reward, by performing simultaneous Positron Emission…
- Trial name
- NCT03447561
- Testing
- Anticipatory + consummatory food reward, Consummatory food reward
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Behavior, Eating
Effect of High-fat/High-sugar Diet on Food Reward Signaling
In this randomized, single-blinded basic research study, healthy normal-weight human participants are exposed to a high-fat/high-sugar (HF/HS) snack or a low-fat/low-sugar (LF/LS) snack twice a day for eight weeks in addition to…
- Trial name
- NCT05574660
- Testing
- High-Fat/High-Sugar (HF/HS) Diet, Low-Fat/Low-Sugar (LF/LS) Diet
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Max Planck Institute for Metabolism Research
Obesity
Crave Crush Neuroimaging Study
The purpose of the research is to test whether a gymnemic acids (GA) lozenge will reduce reward region response to intake of high-sugar food and ad lib candy intake and whether the GA lozenge reduced reward region response to…
- Trial name
- NCT02949102
- Testing
- Crave Crush
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Eating Disorders, Eating Behavior
Food Reward Circuit Change by Orthodontics
It has been described in obese individuals in which decreased basal metabolism as well as dopaminergic changes in the prefrontal cortex and striatum parallels the increased activation of reward brain regions in response to…
- Conditions
- Eating Disorders, Eating Behavior, Eating Habit, Orthodontic Appliance Complication
- Trial name
- DTI (NCT05026411)
- Testing
- T 0 Diffusion Tensor MR, T 1 Diffusion Tensor MR, T 2 Diffusion Tensor MR
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Type 2 Diabetes Mellitus, Obesity
DECREASE: Dapagliflozin Plus Exenatide on Central REgulation of Appetite in diabeteS typE 2
This is a 16 week, phase 4, randomized and placebo controlled trial, investigating the separate and combined effects of Sodium Glucose coTransporter 2 (SGLT2) inhibition with dapagliflozin and Glucagon Like peptide-1 (GLP-1)…
- Trial name
- DECREASE (NCT03361098)
- Testing
- Dapagliflozin 10mg, Exenatide
- Where
- Netherlands
- Volunteers
- 65 people
- Sponsor
- Amsterdam UMC, location VUmc
Obesity
Investigation of the Effects of Bariatric Surgery on Taste Reward in Humans
The investigators hypothesize that some of these changes in the reduced appetite after surgery may be due to alterations in taste.
- Trial name
- NCT01531738
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Obesity, Appetitive Behavior
Regulation of Energy Balance and Metabolism - Mechanisms Behind and Beyond Obesity and Weight Loss
The study aims to investigate homeostatic and hedonic mechanisms regulating appetite, energy balance and metabolism in obesity and the effects of three distinct obesity treatments on these regulatory mechanisms.
- Trial name
- BALANCE (NCT03550339)
- Testing
- SURG, DIET, HAES
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland