Clinical trials: Food Safety
Metabolic Syndrome
Non-Comparative Study to Assess the Efficacy and Safety of the New Food Supplement FaseMETS
The primary objective is to evaluate the efficacy of FaseMETS for 6 consecutive months in lowering serum lipids and glucose in subjects with Metabolic Syndrome; The secondary objectives of the trial are: to evaluate the potential…
- Trial name
- NCT02912325
- Testing
- Daily administration: 2 tablets FaseMETS a day
- Where
- 2 sites in Romania
- Volunteers
- 34 people
- Sponsor
- MDM S.p.A.
Healthy Participants
A Study to Evaluate the Safety, Tolerability, Drug Levels, Food, Formulation, and pH Effects on Relative Absorption of BMS-986465 and Its Active Derivative BMS-986464 in Healthy Participants
The purpose of this study is to evaluate safety, tolerability, drug and food effects on relative bioavailability of BMS-986465 and its active derivative BMS-986464 in healthy participants and healthy participants of Japanese…
- Trial name
- NCT06144697
- Testing
- BMS-986465, Pegasys, Famotidine
- Where
- 2 sites in United States
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Nutrition, Healthy, Type 2 Diabetes
Medically Tailored Groceries and Food Resource Coaching
Eating healthy foods can help people manage health problems, like Type 2 diabetes and heart disease. Many people want to eat healthier, but changing eating behaviors is hard.
- Conditions
- Nutrition, Healthy, Type 2 Diabetes, Hypertension, Dyslipidemias
- Trial name
- NCT06242808
- Testing
- Food resource coaching, Free community food support, Medically tailored groceries
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- University of Texas Southwestern Medical Center
GERD (Gastroesophageal Reflux Disease)
Study to Evaluate the Effect of Food on the Pharmacokinetics and Pharmacodynamics Characteristics in Healthy Adult Volunteers
A Randomized, Open-label, Oral in healthy volunteers
- Trial name
- NCT07364838
- Testing
- DW4421
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Healthy Participants
Study to Evaluate IMG-004 in Healthy Participants
A Phase 1, Randomized, Double-blind, Placebo-controlled Study of Orally Administered IMG-004 to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Dose(s) and an Open-Label Study of Single…
- Trial name
- NCT05349097
- Testing
- SAD IMG-004 30mg, SAD IMG-004 100mg, SAD IMG-004 200mg
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Inmagene LLC
Food Safety
Evaluation of Safety and Tolerability of a Rapeseed Food Ingredient
The study is designed to assess the safety and tolerability of a novel food ingredient produced from rape seeds supplied as a snack-bar in a 4-week controlled intervention.
- Trial name
- RYPSI-ING (NCT03596346)
- Testing
- Rapeseed ingredient (RI), Control product without added RI
- Where
- Finland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Avena Nordic Grain Oy
Healthy Participants
Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics of YD0293 in Healthy Subjects
This study is a single-center, single- and multiple-dose escalating study with a food-effect component, designed to evaluate the safety, tolerability, and pharmacokinetic (PK) characteristics of YD0293 tablets following a single…
- Trial name
- NCT07098091
- Testing
- YD0293
- Where
- China
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Shanghai Yidian Pharmaceutical Technology Development Co., Ltd.
Healthy Participants
A Study to Evaluate Safety, Pharmacokinetics, Pharmacodynamics, Food Effects, and Drug-drug Interactions of ACP-196 in Healthy Participants
This study is to evaluate the safety, pharmacokinetics/pharmacodynamics (PK/PD), food-effect, and drug-drug interaction study of ACP-196 in healthy participants.
- Trial name
- NCT04901923
- Testing
- ACP-196, Itraconazole
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Acerta Pharma BV
Chronic Inducible Urticaria, Chronic Spontaneous Urticaria
A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Doses of EDP-978 in Healthy Adults
This study is a randomized, double-blind, sponsor-open, placebo-controlled study. It will assess the safety, tolerability, pharmacokinetics and pharmacodynamics of orally administered single and multiple doses of EDP-978 in…
- Trial name
- NCT07540910
- Testing
- EDP-978
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Enanta Pharmaceuticals, Inc
Adult Attention-deficit Hyperactivity Disorder (ADHD)
A Phase 1 Study to Investigate the Safety, Tolerance, Food Effect, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of Extended Release Formulations of Centanafadine (CTN) in Young Healthy Subjects
The purpose of this study is to investigate the safety, tolerance, food effect, pharmacokinetics (PK) and pharmacodynamics (PD) of single and multiple doses of extended release (XR) formulations of Centanafadine (CTN) in Young…
- Trial name
- NCT02827513
- Testing
- CTN SR1, CTN XR1, CTN XR2
- Where
- Australia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Peanut Allergy
Evaluating the Safety and Efficacy of Oral Encapsulated Fecal Microbiota Transplant in Peanut Allergic Patients
This is a Phase I trial to evaluate the safety and efficacy of oral encapsulated fecal microbiota transplantation (FMT) in the treatment of peanut allergy.
- Trial name
- NCT02960074
- Testing
- Fecal Microbiota Capsule
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Rima Rachid
Educational Interventions, Virtual Reality
Comparison of Teaching Effectiveness of VR, Video, and Written Materials on Food Hygiene and Equipment Safety
This study investigates the impact of virtual reality (VR) as an educational tool in the food industry, comparing it to traditional methods like videos and written materials in teaching hygiene and safety.
- Trial name
- NCT06669988
- Testing
- VR, Video, written materials
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fu Jen Catholic University
Cancer
Effect of Food Upon Pharmacokinetics of Single Oral Dose of Cediranib (AZD2171, Recentin™)
The purpose of this study is to determine whether food has any effect on a single dose of Cediranib (AZD2171, Recentin™)followed by an assessment of the safety and tolerability of fixed daily dosing in comparison to varying dose…
- Trial name
- NCT00306891
- Testing
- Cediranib, Cediranib 30 - 90 mg
- Where
- 4 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- AstraZeneca
Healthy Volunteer
Safety, Tolerability and Pharmacokinetics of Genz-682452 in Healthy Men
The objectives of this study are to assess the tolerability, safety and pharmacokinetic parameters of Genz-682452 in healthy adult males, in two parts.
- Trial name
- NCT01674036
- Testing
- Genz-682452
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Genzyme, a Sanofi Company
Idiopathic Pulmonary Fibrosis
To Evaluate Food Effect on the PK and Safety After Oral DWN12088 Administration in Healthy Adult Volunteers
The pharmacokinetics (PK) and safety of single oral dose of DWN12088 in healthy adults will be compared and assessed on an empty stomach, after high-fat meal, or 2 hours after high-fat meal.
- Trial name
- NCT04767815
- Testing
- Diet A group, Diet B group, Diet C group
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Healthy Participants
A Study to Find a Suitable Dose of ASP8731 and Check for Medical Problems at Each Dose in Healthy Adults
ASP8731 is a potential new treatment for people with sickle cell disease. Before ASP8731 is available as a treatment, the researchers need to understand how it is processed by and acts upon the body.
- Trial name
- NCT05167526
- Testing
- ASP8731
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Global Development, Inc.
SARS CoV 2 Infection
A Study of EDP-235 in Healthy Subjects
This study is a randomized, double-blind, placebo-controlled study. It will assess the safety, tolerability, and pharmacokinetics of orally administered single and multiple doses of EDP-235 in healthy adult subjects.
- Trial name
- NCT05246878
- Testing
- EDP-235
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Enanta Pharmaceuticals, Inc
Supplemental Nutrition Assistance Program Education, Bhutanese Refugee Adults
The Impact of SNAP-Ed Among Bhutanese Adults Residing in New Hampshire
The goal of this pilot randomized controlled trial is to test the potential efficacy of Supplemental Nutrition Assistance Program Education (SNAP-Ed) among Bhutanese refugee adults residing in New Hampshire.
- Trial name
- NCT06445452
- Testing
- Direct SNAP-Ed
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of New Hampshire
Healthy
Safety, Pharmacokinetics (PK) and Relative Bioavailability of NTP42:KVA4 as a Solid Oral Dose
This Phase 1 clinical trial will assess the safety, tolerability and pharmacokinetics (PK) of a solid capsule form of NTP42:KVA4 in male and female healthy volunteers.
- Trial name
- NCT06092788
- Testing
- NTP42:KVA4 Capsule, NTP42:KVA4 Liquid
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- ATXA Therapeutics Limited
Food Allergy in Children
Sustained Unresponsiveness (SU) to Sesame Protein Following Low-dose Oral Allergen-specific Immunotherapy
This study is a long-term follow-up of participants from the randomized controlled trial (RCT) "Efficacy and Safety of Low-Dose Sesame Oral Immunotherapy in Pediatric Patients", NCT06261554.
- Trial name
- NCT07107451
- Testing
- OIT with low dose sesame protein
- Where
- Poland
- Volunteers
- 39 people
- Sponsor
- Medical University of Warsaw