Clinical trials: Foot, open to volunteers
Diabetic Foot Ulcer
Diabetes Related Foot Ulcers With Negative Pressure Wound Therapy
The goal of this study is to learn if the clinical effects of Negative Pressure Wound Therapy (NPWT) is better, worse or the same as standard wound care for patients with diabetic foot ulcers (DFUs).
- Trial name
- DIANE (NCT06721754)
- Testing
- Negative Pressure Wound Treatment
- Where
- 2 sites in Norway
- Volunteers
- 50 people
- Sponsor
- University Hospital, Akershus
Progressive Collapsing Foot Deformity
Three Foot Orthosis Interventions for Progressive Collapsing Foot Deformity
Background Progressive collapsing foot deformity (PCFD) is a painful musculoskeletal disorder leading to a progressively developing flat foot, which affects mobility and function and negatively impairs quality of life.
- Trial name
- NCT07756372
- Testing
- Customized foot orthoses, Exercise, Podiatric Education
- Where
- 2 sites in Canada
- Volunteers
- 198 people
- Sponsor
- Université du Québec à Trois-Rivières
Plantar Plate Tear
Foot/Extremities at 7T MRI
To evaluate standard clinical sequences for 7 Tesla MRI of the foot and extremities to improve detailed depiction of the complex anatomy of this region.
- Trial name
- NCT04441983
- Testing
- 7 Tesla MRI of the foot
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Diabetes Mellitus, Type 2, Diabetic Foot
Non-invasive Imaging for In-vivo Quantification of Skin Composition and Structure
The goal of this clinical investigation is to explore a non-invasive technology for measuring the microcirculatory structure, composition and function in patients from a primary care population. The main aims are: 1.
- Conditions
- Diabetes Mellitus, Type 2, Diabetic Foot, Peripheral Arterial Disease, Skin Cancer
- Trial name
- Spectrum1 (NCT06976073)
- Where
- 3 sites in Sweden
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- HJN Sverige AB/Neko Health
Diabetic Foot Ulcer, DFU
Randomized Evaluation of Nonhealing Diabetic Foot Ulcers With Exclusive Wound Therapy
The goal of this study is to determine the between-arm difference in the proportion of subjects achieving complete closure of nonhealing diabetic foot ulcers with multiple CAMPs plus SOC versus matched controls over 12 weeks…
- Conditions
- Diabetic Foot Ulcer, DFU, Diabetic Foot Ulcer (DFU), Foot Ulcer Due to Type 1 Diabetes Mellitus
- Trial name
- RENEW (NCT07086443)
- Testing
- Activate™ Matrix, AmnioDefend™ FT Matrix, Palisade™ DM Matrix
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Sequence LifeScience, Inc.
Hepatitis B
The Effect of Hot Foot Bath on Sleep Quality and Fatigue
This study will be conducted to investigate the effects of hot foot baths on patients' sleep quality and fatigue severity levels.The study will be conducted in the Gastroenterology clinic of a university hospital in Türkiye.
- Trial name
- NCT06864923
- Testing
- Hot foot bath application group
- Volunteers
- 60 people
- Sponsor
- Uludag University
Diabetic Foot Ulcer
Placental Cells for Diabetic Foot Ulcers
The purpose of this research study is to test the safety of placental stem cells to treat non-healing diabetic foot ulcers.
- Trial name
- NCT07686094
- Testing
- Placenta Stem Cells
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Wake Forest University Health Sciences
Foot Drop, Stroke
Ankle Robotics After Stroke
The randomized study (in Phase II of the U44) compares the efficacy and durability of 9 weeks (18 sessions) of robot-assisted physical therapy (PTR) versus physical therapy (PT) alone on foot drop as assessed by gait biomechanics…
- Conditions
- Foot Drop, Stroke, Hemiparesis
- Trial name
- NCT04594837
- Testing
- PTR Physical Therapy while wearing Robot group (Phase II), Physical Therapy Only (Phase II), Cross over group for Physical Therapy n Sub-Acute group. (Phase II)
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- NextStep Robotics Inc.
Diabete Mellitus, Foot Ulcer Chronic
Efficacy of Placental Membrane Dressings in Accelerating Diabetic Foot Healing
Evaluation of Efficacy of Placental Membrane Dressings in Accelerating Diabetic Foot Healing
- Trial name
- NCT07326553
- Testing
- Placental Membrane
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- BioXTek
Arterial Insufficiency
Evaluation of a Paraclinical Test for the Diagnosis of Arterial Insufficiency in Diabetic Patients With Foot Ulcers
The number of people living with diabetes has quadrupled worldwide since 1990, and more than 4.5 million people in France have diabetes.
- Trial name
- INFLUX-D (NCT07732270)
- Testing
- Handheld Doppler
- Where
- France
- Volunteers
- 84 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
Gastrocnemius, Ankle Surgery
Efficacy of Gastrocnemius Plane Block for Foot and Ankle Surgery
The study aim is to evaluate the efficacy of the gastrocnemius plane block (GPB) in providing postoperative analgesia for patients undergoing foot and ankle surgery.
- Conditions
- Gastrocnemius, Ankle Surgery, Foot Surgery, Postoperative Analgesia
- Trial name
- NCT07877974
- Testing
- GPB Group : This group will receive ultrasound-guided Gastrocnemius plane block with 30 mL bupivacaine (0.25%), SAB
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Plantar Fasciitis of Both Feet, Plantar Fasciopathy
Effectiveness of Infiltrations in the Treatment of Plantar Fasciopathy
This clinical study aims to evaluate the effectiveness of infiltrations in the treatment of plantar fasciopathy, a painful condition that affects the sole of the foot and is common in active people.
- Trial name
- INFILTRA-PLANT (NCT06671223)
- Testing
- Infiltration, Conservative treatment
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- University of Seville
Diabetic Foot Ulcer (DFU), Pressure Ulcer (PU)
PAW-Hydrogel for Chronic Wound Healing
The goal of this randomized controlled trial is to evaluate the efficacy and safety of a novel hydrogel made of Carbopol® 940 functionalized with Plasma-Activated Water (PAW) in patients with chronic wounds (diabetic foot ulcers…
- Conditions
- Diabetic Foot Ulcer (DFU), Pressure Ulcer (PU), Wound Dehiscence, Venous Leg Ulcer
- Trial name
- NCT07541196
- Testing
- PAW-Functionalized Carbopol® 940 Hydrogel, Standard Advanced Wound Care
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- Benjamín Gonzalo Rodríguez Méndez
Fall Prevention
Evaluation of a Foot Health Program Incorporating Minimalist Footwear on Fall Risk Factors in Older People Living in Senior Nursing Homes: a Pilot Study.
Every year in France, 2 million falls by people over 65 are responsible for 10,000 deaths, the leading cause of accidental death, and more than 130,000 hospitalizations.
- Trial name
- GRAND'PAS (NCT06996444)
- Testing
- Program Including Various Workshops aiming to preserve elderly's autonomy through foot health
- Where
- 5 sites in France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Emile Roux
Type 2 Diabetes Mellitus, Diabetic Neuropathy
GlucoBites Cookies (Gynura Procumbens) for Glycemic Control and Prevention of Diabetic Foot Ulcer Risk in Type 2 Diabetes
The goal of this randomized controlled trial is to learn if GlucoBites functional cookies containing Gynura procumbens can help improve blood sugar control and lower the risk of diabetic foot ulcers in adults with type 2…
- Trial name
- GlucoBites (NCT07151833)
- Testing
- GlucoBites (with Gynura procumbens), Control Cookies (without Gynura procumbens)
- Where
- Indonesia
- Volunteers
- 126 people
- Sponsor
- Andina Setyawati
Primigravida Women, Music Therapy
Effect of Music and Warm Foot Bath Therapy on Pregnancy-Related Anxiety, Blood Pressure and Quality of Life
Study Title: The Effects of Music Therapy and Warm Foot Bath on Pregnancy-Related Stress, Blood Pressure, and Quality of Life in Low-Risk Primigravida Women Brief Summary: This randomized controlled trial investigates the impact…
- Conditions
- Primigravida Women, Music Therapy, Blood Pressure Monitoring, Quality of Life
- Trial name
- NCT07064733
- Testing
- Music Therapy, warm water foot bath therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Kırklareli University
Diabetes Mellitus, Claudication, Intermittent
Additional Hyperbaric Oxygen After Lower Extremity Amputation
This study evaluates the effect of additional hyperbaric oxygen therapy after lower extremity amputation. The patients will be randomized after amputation to either a treatment group receiving hyperbaric oxygen therapy, or…
- Conditions
- Diabetes Mellitus, Claudication, Intermittent, Critical Limb Ischemia, Osteomyelitis
- Trial name
- AHOLEA (NCT03594344)
- Testing
- Hyperbaric oxygen therapy
- Where
- 2 sites in Norway
- Volunteers
- 120 people
- Sponsor
- Oslo University Hospital
Pronated Foot
Product Information Analysis and Clinical Verification - Clinical Verification of New Smart Health Medical Shoes/Insoles
As part of foot orthotics, insoles play a crucial role in adjusting biomechanical malalignments of the foot and regulating foot pressure. They are commonly used as a clinical tool for correcting foot problems.
- Trial name
- NCT07298629
- Testing
- 3d printed insole
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Foot Ulcer Due to Type 2 Diabetes Mellitus
Effect of Semaglutide on Healing of Foot Ulcers in Type 2 Diabetes Patients
The aim of this exploratory pilot study is to investigate the effect of semaglutide compared to placebo on healing of foot ulcers in type 2 diabetes patients.
- Trial name
- SEMAFOOT2 (NCT07581145)
- Testing
- Semaglutide, 1.34 mg/mL
- Where
- Denmark
- Volunteers
- 52 people
- Sponsor
- Ole Lander Svendsen
Posterior Tibial Tendon Dysfunction
Blood Flow Restriction Training in Women With Posterior Tibial Tendon Dysfunction
Posterior tibial tendon dysfunction (PTTD) is a common musculoskeletal disorder characterized by pain, impaired foot function, and reduced dynamic stability.
- Trial name
- BFR-PTTD (NCT07750106)
- Testing
- Blood Flow Restriction Training, Conventional Physical Therapy Program
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- May University in Cairo