Clinical trials: Foot Injuries
Neuropathic Diabetic Ulcer - Foot
Open Multi-center Safety & Efficacy Study of Low Frequency Magnetic Fields to Treat Unresponsive Diabetic Foot Ulcers.
An open multicenter trial to document the efficacy and safety of two therapeutic Extremely Low Frequency Magnetic Fields stimulation devices to promote wound healing of Diabetic Foot Ulcers.
- Trial name
- NCT02145962
- Testing
- Forearm tissue exposure with ELF-MF, Thorax tissue exposure with ELF-MF
- Where
- 2 sites in Mexico
- Volunteers
- 27 people
- Sponsor
- Autonomous University of Morelos
Musculoskeletal Pain, Musculoskeletal Injury
The Diagnostic Accuracy of the Clinical Examination
This study examines the diagnostic accuracy of the clinical examination as compared to MRI findings
- Trial name
- NCT03850470
- Testing
- clinical examination, MRI
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- High Point University
Pressure Ulcers, Venous Ulcers
Use of Fish Skin Extracellular Matrix (ECM) to Facilitate Chronic Wound Healing
The clinical study is designed to assess the effectiveness, safety and non-immunogenicity of fish skin wound dressing extracellular matrix (ECM) in treating chronic wounds.
- Conditions
- Pressure Ulcers, Venous Ulcers, Diabetic Ulcers, Chronic Ulcer of Foot
- Trial name
- NCT01348581
- Testing
- Marigen Wound Dressing
- Where
- Iceland
- Volunteers
- 37 people
- Sponsor
- Kerecis Ltd.
Lower Limb; Fusion, Congenital, Lower Limb Fracture
Investigating Auto Adjusting Dynamic AFO
Offloading Ankle Foot Orthoses (AFOs) are devices designed for people following lower-limb reconstruction to restore mobility by reducing mechanical loading through the injury site and redistributing it proximally.
- Conditions
- Lower Limb; Fusion, Congenital, Lower Limb Fracture, Ankle Foot Injury
- Trial name
- NCT04623853
- Testing
- Variable Stiffness AFO
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Washington
Diabetic Ulcer
Endogenous Progenitors Cell Therapy for Diabetic Foot Ulcers
Diabetic foot ulcers, a complication of diabetes leading to 80.000 lower limb amputations annually in the US, are a significant burden to our health system, costing more than a billion dollars annually.
- Trial name
- AMD3100 (NCT01353937)
- Testing
- AMD3100 injection + rhPDGF-BB topical
- Where
- United States
- Sponsor
- NYU Langone Health
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg
Onset Time of Nerve Block: A Comparison of Two Injection Locations in Patients Having Lower Leg/ Foot Surgery
The purpose of this study is to compare injecting local anesthetic (numbing medication) in different patterns around a major nerve in the leg.
- Conditions
- Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/or Foot
- Trial name
- NCT01542840
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Stroke, Craniocerebral Trauma
Pilot Study Assessing the Feasibility of Treating Foot Drop With the Neurostep™ System.
This pilot feasibility study is assessing the safety and technical performance of the Neurostep™ System for the restoration of independent gait in subjects with gait disorder (i.e. foot drop) secondary to a CNS lesion (e.g.
- Trial name
- NCT00860210
- Testing
- Neurostep™ System
- Where
- 4 sites in Canada, India and 1 more
- Volunteers
- 14 people
- Sponsor
- Neurostream Technologies G.P.
Diabetic Wound
EUSOL vs. PDGF Dressing for Diabetic Foot Ulcers
Diabetic foot ulcers are a major cause of morbidity and amputation. This randomized controlled trial will compare the efficacy of a traditional antiseptic dressing (EUSOL) with a modern biologic dressing containing…
- Trial name
- NCT07493343
- Testing
- EUSOL Dressing, Platelet-Derived Growth Factor (PDGF) Dressing
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Services Hospital, Lahore
Diabetic Foot Ulcers
A Study of Granexin Gel in the Treatment of Diabetic Foot Ulcer
The purpose of this study is to determine whether Granexin gel is safe and effective in the treatment of diabetic foot ulcers.
- Trial name
- NCT02667327
- Testing
- Granexin gel, Vehicle gel
- Where
- 29 sites in United States, Canada and 3 more
- Volunteers
- 124 people
- Sponsor
- Xequel Bio, Inc.
Diabetic Foot Ulcer
Study of Oasis Ultra in Diabetic Foot Ulcers
Many people with diabetes will develop a non-healing diabetic foot ulcer. Many ways are available to try to get a diabetic foot ulcer to heal, including application of Oasis Ultra.
- Trial name
- NCT01835379
- Testing
- Oasis, Standard
- Where
- 16 sites in United States
- Volunteers
- 82 people
- Sponsor
- Healthpoint
Wound Heal, Ulcer
IDEAL: Efficacy of Porcine Placental Extracellular Matrix Augmented Plus Standard of Care (SOC) Versus SOC Alone for the Management of Diabetic Foot Ulcers
A multi-center, prospective, observer-blinded, randomized controlled clinical trial to evaluate the efficacy of PPECM augmented standard of care versus standard of care alone in the management of hard-to-heal diabetic foot ulcers.
- Trial name
- IDEAL (NCT06616844)
- Testing
- InnovaMatrix® AC
- Where
- 21 sites in United States
- Volunteers
- 235 people
- Sponsor
- ConvaTec Inc.
Ankle Injuries, Foot Injuries
Triage-Based Application of OFAR on the Number of Radiographs Ordered
Foot and ankle injuries account for nearly two million visits to Emergency Departments (EDs) in the United States and Canada each year. Of these injured patients, only 15% are diagnosed with actual fractures of the ankle.
- Trial name
- OFAR (NCT01779804)
- Testing
- OFAR
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lehigh Valley Hospital
Diabetic Foot Ulcers
Maggot Debridement Therapy Versus Conventional Dressing Therapy to Treat Diabetic Foot Ulcers
This is a prospective study of participants with diabetic foot ulcers who will receive either maggot debridement therapy (MDT) or conventional dressing therapy (CDT).
- Trial name
- MDTDF (NCT02816749)
- Testing
- Maggot debridement therapy, Conventional Dressing Therapy
- Where
- 2 sites in China
- Volunteers
- 138 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Diabetic Foot, Regional Anesthesia
Efficacy of Continuous Sciatic Nerve Block in Diabetic Foot Patients
Patients who underwent surgery for diabetic foot were divided into three groups: sciatic nerve block (Group B), continuous nerve catheter (Group C) .
- Conditions
- Diabetic Foot, Regional Anesthesia, Catheter Blockage, Wound Heal
- Trial name
- NCT04212325
- Testing
- Group C (Continuous sciatic nerve block), Group S (sciatic nerve block)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gulhane School of Medicine
Arthritis Foot, Trauma Injury
Artoss Foot and Ankle Surgery Registry
This prospective registry was designed as an observational study to ascertain how commercially available NanoBone products are being used by surgeons performing foot and ankle surgery which involves bone grafting, as well as…
- Conditions
- Arthritis Foot, Trauma Injury, Deformity; Bone
- Trial name
- ARK (NCT04503759)
- Testing
- NanoBone Bone Graft Substitute
- Where
- 8 sites in United States
- Volunteers
- 200 people
- Sponsor
- Artoss Inc.
Wound, Diabetic Foot
Effect of the Use of Low Intensity Therapeutic LASER
Diabetes mellitus consists of a heterogeneous group of metabolic disorders that have hyperglycemia in common, resulting from defects in insulin action, insulin secretion, or both.
- Conditions
- Wound, Diabetic Foot, LTBI
- Trial name
- NCT05530486
- Testing
- CC, LG1, LG2
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Federal University of Piaui
Diabetic Foot Ulcers
Acellular Porcine Dermal Matrix Wound Dressing in the Management of Diabetic Foot Ulcers
Have indolent diabetic ulcers completely healed by the Acellular Porcine Dermal Matrix (APM) in 12 weeks.
- Trial name
- NCT01353495
- Testing
- APM Graft (BIOTAPE XMTM), Wound Debridement
- Where
- 2 sites in United States
- Volunteers
- 39 people
- Sponsor
- Stryker Trauma and Extremities
Compresion Therapy, Post-operative Edema
Post-operative Complication, Impulsive Compression, in Situ Bypass
To investigate whether compression therapy with foot pump reduce post-operative edema, facilitate wound healing of operation wounds, promote healing of ischemic ulcers and shorten hospitalization, increase and improve the…
- Conditions
- Compresion Therapy, Post-operative Edema, Wound Complication, Ischemia Limb
- Trial name
- 50506 (NCT03192982)
- Testing
- A-V impulse 6000 Series, Standard treatment (compression)
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Kolding Sygehus
Diabetic Foot Ulcers
Effectiveness of Aurix Therapy in Diabetic Foot Ulcers
The aim of this trial is to demonstrate the effectiveness of complete wound healing in a prospective, open-label, randomized trial in which diabetic food ulcers (DFU) will be treated using Aurix plus Usual and Customary Care…
- Trial name
- NCT02352480
- Testing
- Aurix
- Where
- 20 sites in United States
- Volunteers
- 760 people
- Sponsor
- Nuo Therapeutics
Pressure Ulcer, Diabetic Foot Ulcer
Efficacy of Wound Dressings With Copper Oxide
Thirty patients of 18-85 years of age, with 2-30 cm2 pressure ulcers or post-op wounds, will be recruited and treated with either wound dressing containing silver or wound dressings containing copper oxide microparticles.
- Trial name
- NCT04634838
- Testing
- MedCu Antibacterial Wound Dressings with Copper Oxide
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- MedCu Technologies Ltd.