Clinical trials: Foot Pain
Restless Legs Syndrome
Neuroma Injections to Treat Restless Legs Syndrome - RCT
The purpose of this study is to determine whether, in a randomized, placebo-controlled trial, restless legs syndrome (RLS) can be caused by pinched and damaged foot nerves called neuromas.
- Trial name
- NCT00656110
- Testing
- equal parts of 0.5% plain Marcaine and 2% lidocaine mixed with 0.8 mg Depo-medrol/4% absolute alcohol in a total injection volume of 1 ml, Normal saline - 1ml
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Lowcountry Infectious Diseases
Carpal Tunnel Surgery, Trigger Finger Disorder
NAC-REPAIR for Post-surgical Pain
This pilot asks whether peri-operative N-acetylcysteine (NAC) improves recovery after common outpatient hand/foot-ankle surgery-specifically, does NAC reduce pain and opioid use and enhance function by modulating…
- Conditions
- Carpal Tunnel Surgery, Trigger Finger Disorder, De Quervain Syndrome, Guyon's Canal
- Trial name
- NCT07227649
- Testing
- NAC
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Arizona
Leg Length Inequality, Foot Deformities
Botox Clinical Trial
The surgery to correct leg \& foot deformities in children is a lengthy, \& sometimes, difficult procedure. Metal frames are attached to the leg and / or foot and over a period of time the frame is manipulated to obtain the…
- Trial name
- NCT00624299
- Testing
- Botox, Saline
- Where
- United Kingdom
- Sponsor
- Sheffield Children's NHS Foundation Trust
Hallux Valgus
Home Infusors for Analgesia After Foot Surgery
The purpose of this double blind, randomized study is to evaluate which rate and duration of infusion can be recommended for continuous perisciatic infusion of ropivacaine 2 mg/ml for analgesia after ambulatory foot surgery.
- Trial name
- NCT00600899
- Testing
- elastomeric pump with reservoir of 500 ml, infusion rate of 8 ml/h, elastomeric pump with reservoir of 275 ml, infusion rate of 5 ml/h
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Frederiksberg University Hospital
Sports Physical Therapy
Calcaneal Low Dye Taping Plantar Fascial Stretching and Sham Taping in Football Players
Showing the effect of calcaneal Low-dye Taping on acute planter heel pain and functional activity level in football players.
- Trial name
- NCT05736809
- Testing
- Low-dye taping, Plantar fascia stretching
- Where
- Pakistan
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Frail Elderly
Effect of Hot Water Foot Bath on Daily Living Activities, Insomnia and Fatigue Levels in Frail Geriatric Individuals
Aim: A randomized controlled experimental study was conducted to determine the effect of hot water foot bath on daily living activities, sleep and fatigue levels in frail geriatric individuals.
- Trial name
- NCT07048015
- Testing
- Hot Water Foot Bath
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Hallux Valgus, Pain
Initial Effects of Kinesiotaping in Non Surgical Treatment of Hallux Valgus
The main aim of this study was to find the initial effects of kinesiotaping on pain and joint alignment used in the conservative treatment of hallux valgus.
- Trial name
- NCT01952691
- Testing
- kinesiotaping
- Volunteers
- 22 people
- Sponsor
- Hacettepe University
Acute Pain, Bunion
Study of Wafermine™ for Post-bunionectomy or Abdominoplasty Pain
This study evaluates the safety and effectiveness of Wafermine™ for post-bunionectomy or post-abdominoplasty pain over a 24 hours period.
- Conditions
- Acute Pain, Bunion, Abdominoplasty
- Trial name
- NCT03246971
- Testing
- Wafermine™ 50 mg, Wafermine™ 75 mg, Wafermine™ 25 mg
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- iX Biopharma Ltd.
Morton Neuroma
Insole on Morton's Neuroma
Objective: The aim of the present study was to assess the effectiveness of insole with metatarsal support on pain in patients with Morton's neuroma and the impact of this insole on function, load distribution in the plantar…
- Trial name
- NCT03511677
- Testing
- Insole
- Volunteers
- 72 people
- Sponsor
- Federal University of São Paulo
Anterior Knee Pain Syndrome, Pronated Foot
Efficacy of Neuromuscular Training and Manual Therapy With Augmented Low-Dye Taping Technique for Correction of Pronated Foot in the Management of Anterior Knee Pain
The goal of this clinical trial] is to To find out the effect of Neuromuscular Training and Manual therapy with Augmented Low - Dye Taping technique for correction of Pronated foot in the management of Anterior knee pain…
- Trial name
- AKPS NPRS FPI (NCT05917080)
- Testing
- Manual Therapy
- Where
- United Arab Emirates
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mediclinic Al Noor Hospital
Plantar Fascitis
Active Release Technique Versus Strain-Counter Strain in Improving Pain and Function in Plantar Fasciitis
This randomized controlled trial compares the effectiveness of Active Release Technique (ART) and Strain-Counterstrain (SCS) in treating plantar fasciitis.
- Trial name
- NCT07078513
- Testing
- Active release Technique, Strain counter strain tecnhnique
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Neuroma
ALGRX 4975 in the Treatment of Patients With Morton's Neuroma
Subjects will have painful primary or post-operative intermetatarsal neuroma. Study drug or placebo will be injected into the space containing the neuroma.
- Trial name
- NCT00130962
- Testing
- ALGRX 4975
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- AlgoRx Pharmaceuticals
Plantar Fasciitis
A Trial of Custom Foot Orthoses for the Treatment of Plantar Heel Pain
This is a study investigating treatment of plantar fasciitis (heel pain). Physicians commonly prescribe specialized orthoses (shoe inserts) to treat heel pain.
- Trial name
- NCT00765843
- Testing
- orthoses
- Where
- 2 sites in United States
- Volunteers
- 77 people
- Sponsor
- Rosalind Franklin University of Medicine and Science
Hallux Valgus, Bunionectomy
Sciatic Nerve Block With ALX006 in Subjects Undergoing Bunionectomy
This is a Phase 2, randomized, double-blind, active-controlled, dose-escalation study evaluating the safety, pharmacokinetics, efficacy, and pharmacodynamics of ALX006, an extended-release bupivacaine formulation, administered as…
- Trial name
- NCT07574385
- Testing
- ALX006 (bupivacaine extended-release injection), Bupivacaine Hcl 0.25% Inj, Sciatic Nerve Block
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Rebel Medicine Inc
Bunion, Post-operative Pain
CPL-01 in the Management of Postoperative Pain After Bunionectomy
Subjects receive study drug during bunionectomy and are followed for pain and opioid use, with the hypothesis that those who receive CPL-01 will have less pain and less opioid use than either control arm.
- Trial name
- NCT05831449
- Testing
- Local anesthetic injection of CPL-01, Naropin, 0.5% Injectable Solution, Morphine rescue medication
- Where
- United States
- Volunteers
- 616 people
- Sponsor
- Cali Pharmaceuticals LLC
Knee Pain Treated With Knee Arthroplasty
Changes of Plantar Pressure After Knee Reconstructive Surgery
Knee reconstructive surgery (knee prosthesis, osteotomies) often results in changes of alignment of the lower limb axis. This affects also biomechanics of the hindfoot.
- Trial name
- PEDKnee (NCT02906735)
- Testing
- Surgery
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Chronic Neuropathic Pain
A Post Market Cohort to Assess the Performance of the Spinal Modulation Neurostimulator System for the Management of Chronic Neuropathic Pain of the Foot and/or Lower Leg
14-SMI-2013 is a post market, observational, questionnaire based study to assess the effectiveness of the commercially available Axium neurostimulator in the management of neuropathic pain of the foot and/or lower limb
- Trial name
- NCT02335489
- Testing
- Implantation with the commercially available Axium neurostimulator
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Abbott Medical Devices
Arthritis of Knee
Hyperpronation and Foot Pain
Effects of training and pellots
- Trial name
- NCT00736138
- Testing
- training and pellots
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Ankle Osteoarthritis, Flat Foot or Pes Planus
Orthotic Dose Response Study
This study will investigate the effect of foot orthoses on two common conditions (ankle osteoarthritis and symptomatic adult onset flat feet) by using a custom biplane X-ray system the group has developed to very accurately and…
- Trial name
- ODRS (NCT02629731)
- Testing
- custom orthoses with varying degrees of hindfoot posting
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Heel Pain Syndrome
Treating Heel Pain in Adults: A Randomized Clinical Trial of Hard Versus Soft Orthotics
Objectives: This study compared the effectiveness of soft versus hard orthotics in treating heel pain and plantar fasciitis in adults.
- Trial name
- NCT04380285
- Testing
- Custom heel pads and modified soft molded orthotics, Custom hard orthotic
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Deborah Seligman, MSc., B.Sc.O.T.