Clinical trials: Foot Pathology
Peripheral Nervous System Diseases, Gait Disorders, Neurologic
Seated Ankle Robot for Foot Drop in Aging and Disabled Populations: A Demonstration Project
The purpose of this research study is to test the utility of an ankle robot in people with ankle weakness and foot drop from a peripheral nervous system injury due to neuromuscular or orthopedic injury.
- Conditions
- Peripheral Nervous System Diseases, Gait Disorders, Neurologic, Foot Drop, Mobility Limitation
- Trial name
- NCT03530592
- Testing
- Seated Ankle Robot Training
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Baltimore VA Medical Center
Clubfoot
Clubfoot Tenotomy Trial
Infants undergoing Ponseti treatment for idiopathic clubfoot often require percutaneous tendoachilles lengthening (TAL) after serial casting.
- Trial name
- ClubTT (NCT04766684)
- Testing
- Jet injection of 1% lidocaine, 4% liposomal lidocaine cream
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Vanderbilt University Medical Center
Critical Limb Ischemia, Critical Lower Limb Ischemia
PROMISE II: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia
The LimFlow System is intended for endovascular, minimally invasive procedures in patients who have a clinical diagnosis of chronic limb-threatening ischemia and who have been determined to have no surgical or endovascular…
- Conditions
- Critical Limb Ischemia, Critical Lower Limb Ischemia, Peripheral Artery Disease, Peripheral Arterial Disease
- Trial name
- PROMISE (NCT03970538)
- Testing
- LimFlow System
- Where
- 21 sites in United States, Puerto Rico
- Volunteers
- 105 people
- Sponsor
- LimFlow, Inc.
Hallux Limitus, Movement, Abnormal
Foot Posture Index, Hallux Limitus in Patients With Chronic Low Back Pain. Gait With Optogait Sensor
Foot disorders have been recognized as being linked to chronic low back pain
- Conditions
- Hallux Limitus, Movement, Abnormal, Back Pain Lower Back Chronic
- Trial name
- NCT04607863
- Testing
- Case control
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Seville
Postoperative Pain, Gastrointestinal Motility Disorder
The Effect of Foot Reflexology After Cesarean Section
Standardized, quality and evidence-based nursing care after cesarean section is important to prevent or minimize complications that may occur after cesarean section.
- Trial name
- NCT05268328
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Nülüfer Erbil
Postoperative Pain
Bunionectomy Study for Postoperative Analgesia (EPOCH 1)
This is a Phase 3, randomized, double-blind, saline placebo- and active-controlled, multicenter study to evaluate the analgesic efficacy and safety of HTX 011 administered via local administration into the surgical site in…
- Trial name
- NCT03295721
- Testing
- HTX-011, Bupivacaine HCl, Luer-lock applicator
- Where
- 15 sites in United States
- Volunteers
- 412 people
- Sponsor
- Heron Therapeutics
Diabetic Foot Ulcers, Diabetic Foot Wounds
Wound Edge Changes Following Treatment With Santyl
The goal of this study is to evaluate changes in the healing tissue of diabetic foot wounds following 14 days of treatment with Santyl or its vehicle base.
- Trial name
- NCT01197898
- Testing
- Collagenase Santyl Ointment
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Healthpoint
Lower Back Pain
Osteopathic Treatment in Patients With Low Back Pain: Stabilometry
Determine the improvement in nonspecific low back pain patients with osteopathic techniques (Body Adjustment Protocol) and know changes in stabilometric measures analyzed with a stabilometric platform (Footscan®).
- Trial name
- Osteop-COP (NCT02518360)
- Testing
- Osteopathic, Auto Stretching
- Volunteers
- 50 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Pes Planus
Low Dye Taping Technique and Temporary Felt Insoles on Pain and Disability in Children With Pes Planus.
This study aims to determine comparative effects of low dye taping technique and temporary felt insoles on pain and disability in children with pes planus.
- Trial name
- NCT05764967
- Testing
- Low Dye Taping, Temporary Felt Insoles
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Surgery, Edema
Foot and Ankle Post-operative Oedema Management Using Geko™
The multicentre randomised geko™ Foot and Ankle Trial will prospectively and systematically collect clinical data on patients randomised, on a 1:1 basis, to either standard care or standard care plus geko™ therapy to assess…
- Trial name
- NCT04927234
- Testing
- geko™ therapy
- Where
- 5 sites in United States, Spain and 1 more
- Volunteers
- 123 people
- Sponsor
- Firstkind Ltd
Frail Elderly
Effect of Hot Water Foot Bath on Daily Living Activities, Insomnia and Fatigue Levels in Frail Geriatric Individuals
Aim: A randomized controlled experimental study was conducted to determine the effect of hot water foot bath on daily living activities, sleep and fatigue levels in frail geriatric individuals.
- Trial name
- NCT07048015
- Testing
- Hot Water Foot Bath
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Postoperative Infection, Postoperative Complications
Dilute Betadine Soak and Scrub for Foot and Ankle Surgery
Infection and wound complications are the most common complications following orthopaedic foot and ankle procedures, and the infection rate following these procedures is higher than in procedures involving other areas of the…
- Trial name
- NCT03926208
- Testing
- Soak and Scrub, Clorhexadine scrub
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- Rush University Medical Center
Back Problems or Pain, Foot Problems or Pain
Rehabilitation Coordinators in Orthopedic Care
REKO-O is a study that addressed women and men on sick leave in Uppsala County. Participants which are enrolled in orthopedic care clinic.
- Conditions
- Back Problems or Pain, Foot Problems or Pain, Shoulder Problems or Pain
- Trial name
- REKOO (NCT03944018)
- Testing
- Intervention with rehabilitation coordinator
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Uppsala University
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg
Onset Time of Nerve Block: A Comparison of Two Injection Locations in Patients Having Lower Leg/ Foot Surgery
The purpose of this study is to compare injecting local anesthetic (numbing medication) in different patterns around a major nerve in the leg.
- Conditions
- Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/or Foot
- Trial name
- NCT01542840
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Cerebral Palsy, Muscle Spasticity
Dysport® Pediatric Lower Limb Spasticity Study
The purpose of this research study is to determine whether Dysport® is effective in the treatment of increased stiffness of the calf muscles and to evaluate the safety of this treatment in children with Cerebral Palsy.
- Conditions
- Cerebral Palsy, Muscle Spasticity, Children
- Trial name
- NCT01249417
- Testing
- Botulinum toxin type A
- Where
- 29 sites in United States, Chile and 4 more
- Volunteers
- 241 people
- Sponsor
- Ipsen
Healthy Subjects
Orthopaedic Simulation of Morton's Extension to Test the Effect on Plantar Pressures of Each Metatarsal Head in Patients Without Deformity: A Pre-post-test Study.
The aim of this study is to simulate the orthopedic treatment called Morton's extension on non-deformed patients to check the effects on each metatarsal head on its static footprint.
- Trial name
- NCT05879094
- Testing
- Morton extension
- Where
- Spain
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mayuben Private Clinic
Pronation Deformity of the Foot
Intrinsic Foot Muscle Training With and Without Hip Abductor Muscle Strengthening in Pronation Distortion Syndrome
Pronation distortion syndrome is one of the most common abnormalities in the lower extremity that causes alterations in the structures of the skeletal parts of the foot.
- Trial name
- NCT06407713
- Testing
- Intrinsic foot muscle training, Hip abductor muscle training
- Where
- Pakistan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Diabete Mellitus, Foot Ulcer
Efficacy and Safety of Stimulan® for the Treatment of Diabetic Foot Osteomyelitis. The BIG D-FOOT Study
This study is designed as a double-blind, placebo-controlled, parallel series randomized trial aimed at verifying the effiicacy and safety of a local calcium-sulphate bio-absorbable antibiotic delivery (tobramicina+vancomicina)…
- Conditions
- Diabete Mellitus, Foot Ulcer, Osteomyelitis - Foot, Surgical Procedure, Unspecified
- Trial name
- BIG D-FOOT (NCT06262854)
- Testing
- Calcium-sulphate granules with tobramicina+vancomicina
- Volunteers
- 50 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Normative Algometric Pressures, Foot Pain
Validation of Algometry for Use in the Human Foot
The primary aim is to examine whether there is a consistent range of pressure threshold values for the asymptomatic foot.Previous studies established the inter/intra-clinician reliability of pressure threshold measuring and have…
- Trial name
- NCT01940289
- Testing
- Algometric meter readings for perception of pain
- Where
- United Kingdom
- Volunteers
- 544 people, healthy volunteers welcome
- Sponsor
- Dundee Podiatry Clinic
Diabetic Foot Ulcer, Infection
Topical PluroGel N for the Treatment of Mildly Infected Diabetic Foot Ulcers
This will be a randomized, double-blind (evaluator-blind), vehicle-controlled study of 50 enrolled subjects. Adult subjects (greater than 18 years old) who present with a mildly infected diabetic foot ulcer (IDSA criteria) having…
- Trial name
- NCT02091596
- Testing
- PluroGel N, PluroGel
- Where
- 15 sites in United States
- Volunteers
- 42 people
- Sponsor
- PluroGen Therapeutics, Inc