Clinical trials: Foot Pathology
Chronic Ulcer, Venous Ulcer
Efficacy of PICO Single-use System in Chronic Ulcers
A clinical trial will be carried out comparing the efficacy of PICO system based on negative pressure therapy (NPT) in adults with chronic ulcers compared to conventional treatments.
- Conditions
- Chronic Ulcer, Venous Ulcer, Diabetic Foot Ulcer, Pressure Injury
- Trial name
- NCT05877378
- Testing
- Single-use negative pressure therapy (PICO)
- Where
- Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Flatfoot
Comparison of Two Different Insole Types in Painful Flexible Flatfoot
The purpose of this study is to compare computer aided design/computer aided manufacturing (CAD/CAM) and semi-custom insole types on pain, quality of life and physical performance and also to decide whether they are necessary in…
- Trial name
- NCT02706327
- Testing
- CAD/CAM Insole, Semi-custom Insole, Control
- Volunteers
- 67 people
- Sponsor
- Eastern Mediterranean University
Tinea Pedis, Athlete's Foot
Safety and Efficacy of Econazole Nitrate Foam 1% and Foam Vehicle in Subjects With Tinea Pedis
This is a study of the safety and efficacy of Econazole Nitrate Foam 1% and the Foam Vehicle in subjects with interdigital tinea pedis (athlete's foot between the toes).
- Trial name
- NCT01358240
- Testing
- Econazole Nitrate Foam 1%, Vehicle Foam, Econazole Nitrate Cream 1%
- Where
- 12 sites in United States
- Volunteers
- 336 people
- Sponsor
- AmDerma
Spasticity, Post-Stroke
JCP Study of Investigation of Patient Background Characteristics
To collect the background characteristics of juvenile cerebral palsy patients aged 2-year or older prescribed BOTOX for the treatment of equines foot due to lower limb spasticity, compare them with those of patients whose deaths…
- Trial name
- NCT01332474
- Testing
- BOTOX
- Volunteers
- 326 people
- Sponsor
- GlaxoSmithKline
Diabetes, Foot Ulcer
Hyperbaric Oxygen Therapy as Adjunctive Treatment of Chronic Diabetic Foot Ulcers
The purpose of this study is to evaluate if hyperbaric oxygen therapy heels more foot ulcers as compared to placebo in patients with diabetes mellitus and chronic foot ulcers.
- Conditions
- Diabetes, Foot Ulcer, Healing
- Trial name
- HODFU (NCT00953186)
- Testing
- hyperbaric air, HBOT
- Where
- Sweden
- Volunteers
- 94 people
- Sponsor
- Mrs. Thelma Zoegas Foundation
Chronic Kidney Disease
Risk Factors for Foot Ulceration in the Chronic Kidney Disease (CKD) Population
Foot ulceration is a risk factor that has been associated with early death in patients with chronic kidney disease. Little is known about the relationship between these risk factors that develop in patients with kidney failure…
- Trial name
- NCT01089829
- Testing
- Foot examination
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Cardiff University
Diabetic Foot Ulcers
Phase IV Study to Evaluate the Efficacy of AMNIOEXCEL in Diabetic Foot Ulcers
The primary goal of the study is to demonstrate the increased rate of complete wound closure by AMNIOEXCEL® compared to routine care in patients with chronic diabetic foot ulcers
- Trial name
- NCT02209051
- Testing
- AMNIOEXCEL, Standard of Care, Diabetic Foot Ulcers
- Where
- 8 sites in United States
- Volunteers
- 29 people
- Sponsor
- Integra LifeSciences Corporation
Diabetic Foot Ulcer
Custom Insole With Transcutaneous Electrical Nerve Stimulation on Clinical Outcomes of Diabetic Foot Ulcers
Diabetic foot ulcers (DFUs) are one of the serious complications of diabetes, typically resulting from neuropathy or peripheral arterial disease, and can often lead to amputation.
- Trial name
- NCT07109895
- Testing
- Standard Care Only, Custom Insole + Standard Care, TENS + Custom Insole + Standard Care
- Where
- Pakistan
- Volunteers
- 159 people
- Sponsor
- University of Lahore
Tarsal Tunnel Syndrome
Tarsal Tunnel Syndrome and Fibromyalgia
Widespread pain is observed in patients diagnosed with fibromyalgia, and lower extremity and foot pain are also common. In our study, we aimed to evaluate the relationship between foot pain and tarsal tunnel syndrome in female…
- Trial name
- NCT05135572
- Testing
- Fibromiyalgia and foot pain
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kutahya Health Sciences University
Morton's Neuroma
Resiniferatoxin for the Management of Refractory Morton s Neuroma Pain
Morton s neuroma is an irritation of the nerves that affect the feet. People with this condition may have burning or shooting pain in the balls of their feet. They may also have numbness in adjacent areas.
- Trial name
- NCT05695339
- Testing
- Resiniferatoxin
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Tinea Pedis
Efficacy and Safety of Product S2G6T-1in Patients With Symptomatic Inflammatory Interdigital Tinea Pedis
To assess the efficacy and safety of a combination product S2G6T-1 compared to its monads and vehicle, applied twice daily for 7 days, in the treatment of symptomatic inflammatory interdigital tinea pedis in subjects 12 years of…
- Trial name
- NCT02842021
- Testing
- S2G6T-1, S2G6T-2, S2G6T-3
- Where
- 19 sites in United States
- Volunteers
- 283 people
- Sponsor
- Sol-Gel Technologies, Ltd.
Diabetes Mellitus, Neuropathic Pain
A Study of Intra-dermal Injection of Botulinum Toxin Type A for the Diabetic Neuropathic Foot Pain
Effective treatment of neuropathic foot pain in diabetic patients is very important to improve their quality of life. There are many medications used to reduce the diabetic neuropathic pain, including anticonvulsants…
- Trial name
- NCT00336349
- Testing
- Botulinum Toxin Type A
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Medical University Hospital
Plantar Plate Tear, Metatarsalgia
Evaluation of Clinical and Functional Results After Operative Correction of Lesser Toe Deformities
The plantar plate is an important static stabilizer of lesser metatarsophalangeal joints, and disruptions of the plantar plate can lead to significant instability and lesser toe deformities.Our study proposes an inexpensive and…
- Conditions
- Plantar Plate Tear, Metatarsalgia, Lesser Metatarsophalangeal Joint Instability, Hammer Toe
- Trial name
- NCT04949685
- Testing
- plantar plate repair
- Where
- Taiwan
- Volunteers
- 18 people
- Sponsor
- National Taiwan University Hospital
Chemotherapy-induced Nausea and Vomiting
Effect of Foot Reflexology On Chemotherapy Induced Nausea and Vomiting in Breast Cancer Patients
This study aims to evaluate the effect of foot reflexology on chemotherapy-induced nausea and vomiting in breast cancer patients.
- Trial name
- NCT07322393
- Testing
- Foot Reflexology
- Volunteers
- 50 people
- Sponsor
- University of Health Sciences Lahore
Diabetes Mellitus, Critical Limb Ischemia
Laboratory, Cellular and Molecular Determinants of Clinical Success in Diabetic Patients With Critical Limb Ischemia
The ECAD-CLI is an investigator-driven, prospective, single-center study. The aim of the study is to prospectively collect clinical, laboratory, angiographic, cellular and molecular variables related to prognosis and outcome in…
- Conditions
- Diabetes Mellitus, Critical Limb Ischemia, Critical Lower Limb Ischemia, Diabetic Foot
- Trial name
- ECAD-CLI (NCT03636867)
- Testing
- data and specimen collection
- Where
- Italy
- Volunteers
- 236 people
- Sponsor
- Maria Cecilia Hospital
Morton Neuroma
Is Ultrasonography Comparable to MRI for the Detection of Morton Neuroma of the Foot?
Patients with Morton neuroma of the foot will undergo either ultrasonography or MRI. The results will be compared. In case of surgery, the pathology report will be compared with the ultrasonographic or MRI findings.
- Trial name
- NCT00284414
- Testing
- Ultrasonography or MRI
- Sponsor
- University Hospital, Ghent
Head and Neck Neoplasms, Xerostomia
Foot Reflexology and Ta-VNS for Symptom Management in Head and Neck Cancer During CCRT
Head and neck cancer (HNC) patients undergoing concurrent chemoradiotherapy (CCRT) frequently experience pain, xerostomia, fatigue, sleep disturbance, and other treatment-related toxicities that impair quality of life and…
- Conditions
- Head and Neck Neoplasms, Xerostomia, Cancer-related Fatigue, Pain
- Trial name
- NCT07711626
- Testing
- True Foot Reflexology, True ta-VNS, True Auricular Acupressure
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- Tzu Chi University
Tinea Pedis
A Trial to Evaluate the Safety and and Tolerability of DBI-001 in Patients With Tinea Pedis
This is an open-label, single-dose, dose escalating evaluation of the safety and tolerability of three dose levels of DBI-001 in patients with Tinea pedis.
- Trial name
- NCT04152226
- Testing
- Janthinobacterium lividum
- Where
- Dominican Republic
- Volunteers
- 12 people
- Sponsor
- DermBiont, Inc.
Intensive Care Patients
The Effect of Passive Music Therapy and Foot Massage
Patients hospitalized in tertiary intensive care units are connected to mechanical ventilators due to multiorgan failure, chronic diseases, respiratory failure, etc.
- Trial name
- NCT06078826
- Testing
- passive music therapy, foot massage
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- TC Erciyes University
Peripheral Arterial Disease, Peripheral Vascular Disease
Safety Study of MultiGeneAngio in Patients With Chronic Critical Limb Ischemia
The purpose of this study is to evaluate the safety and activity of two doses of MultiGeneAngio, a cell therapy product produced from the patient's own cells, as potential treatment for patients with chronic critical limb…
- Conditions
- Peripheral Arterial Disease, Peripheral Vascular Disease, Critical Limb Ischemia
- Trial name
- NCT00956332
- Testing
- MultiGeneAngio
- Where
- 7 sites in Israel
- Volunteers
- 28 people
- Sponsor
- MultiGene Vascular Systems Ltd.