Clinical trials: Foot Pathology
Diabetic Foot, Pressure Ulcer
A Real-World Registry of Chronic Wounds and Ulcers
WOUNDJOURNEY is a longitudinal, real-world, observational registry designed to capture the full clinical course and patient journey associated with chronic wounds and ulcers.
- Conditions
- Diabetic Foot, Pressure Ulcer, Surgical Wound Dehiscence, Vasculitis
- Trial name
- WOUNDJOURNEY (NCT02280733)
- Testing
- Usual care
- Where
- United States
- Volunteers
- 300,000 people
- Sponsor
- U.S. Wound Registry
Acute Pain
Effects of Acupressure and Foot Massage on Pain During Heel Lancing in Neonates
Aim: The study was aimed to identifying the effects of foot massage and acupressure on pain during heel lancing in neonates. Methods: A single-blinded randomized controlled trial was performed in a university hospital in Turkey…
- Trial name
- NCT03906552
- Testing
- nonpharmalogocial methods
- Where
- Turkey (Türkiye)
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Adiyaman University Research Hospital
Blister
Hydrogel Blister Patch Prototype Treatment for Foot Blisters on the Heel
Study to evaluate the safety and performance of a new blister patch intended to treat blisters on the heel of the foot.
- Trial name
- NCT01088685
- Testing
- Experimental Blister Patch, Marketed Pflaster
- Where
- Germany
- Volunteers
- 93 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Morton's Neuroma, Pain Management
Cryoanalgesia for the Treatment of Pain in Subjects With Morton's Neuroma
This is a Proof-of-Concept Trial to define the safety, efficacy and feasibility of a cryoanalgesic device (iovera°®) for the treatment of pain in subjects diagnosed with Morton's Neuroma, who have failed conservative therapies.
- Trial name
- NCT05604144
- Testing
- Cryoanalgesia (iovera°®)
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Northern California Research Trials, Inc.
Metatarsalgia, Hyperkeratotic Callus
Pressure Offloading Injectible System With the Use of Juvederm Voluma in the Foot
The current use of Juvederm Voluma XC is indicated for deep (subcutaneous and/or supraperiosteal) injection for cheek augmentation to correct age-related volume deficit in the mid-face in adults over the age of 21.
- Conditions
- Metatarsalgia, Hyperkeratotic Callus, Corns, Fat Pad Syndrome
- Trial name
- POIS (NCT04103866)
- Testing
- Juvederm Voluma
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Schoenhaus, Jodi, DPM
Plantar Fasciitis
Electrolysis in Patients With Chronic Plantar Fasciitis
Aim of the Study The aim of this study is to investigate the differential effects of high-intensity and low-intensity percutaneous electrolysis (PCE) on pain perception and muscle tissue properties in individuals with chronic…
- Trial name
- Electrolysis (NCT06674902)
- Testing
- Electrolysis Percutaneous Therapeutic (EPTE)
- Where
- Spain
- Volunteers
- 16 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
Rheumatoid Arthritis, Rheumatoid Arthritis of Foot (Disorder)
Foot Orthotic for Early Stage Rheumatoid Arthritis
The overall purpose of this project is to investigate the neuro adaptations of pain and biomechanical differences between placebo and a custom-made foot orthoses for patients with RA.
- Trial name
- NCT03561688
- Testing
- Foot orthotics, Standard insole
- Where
- 3 sites in Denmark
- Volunteers
- 27 people
- Sponsor
- Regionshospital Nordjylland
Obesity, Morbid, Foot Deformities
Investigation of the Relationship Between Plantar Foot Pressure and Balance in Morbidly Obese Individuals
The fact that changes in plantar pressure during walking and in a fixed position in morbidly obese individuals and the relationship between postural oscillations and balance have not been fully elucidated creates a need in this…
- Trial name
- NCT05519436
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Diabetic Foot, Gangrene; Limb
MetaMet: Bone Cutter Versus Bone Saw for Ray Amputation
Toe amputation is a commonly performed operation for infection and/or ischaemia (tissue death due to lack of blood flow). However, a large number of patients having this surgery ultimately require further amputation due to poor…
- Conditions
- Diabetic Foot, Gangrene; Limb, Wound Infection, Wound Healing Delayed
- Trial name
- MetaMet (NCT05804565)
- Testing
- Bone Saw, Bone Cutter
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- University College Hospital Galway
Foot Injuries and Disorders, Ankle Injuries and Disorders
Dexamethasone vs. Dexmedetomidine for Popliteal Nerve Block in Pain Management After Pediatric Ankle and Foot Surgery
Effect of perineurial dexamethasone and dexmedetomidine on popliteal nerve block duration for pediatric, ankle or foot surgery
- Trial name
- NCT06233565
- Testing
- 0.9%sodium chloride, Dexamethasone, Dexmedetomidine
- Where
- 2 sites in Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Bunionectomy, Hallux Valgus
Phase 3, Sciatic Nerve Block With EXPAREL for Subjects Undergoing Bunionectomy
The study is conducted sequentially in two parts. Part A: The purpose is to obtain information on pharmacokinetic (PK) profile, pharmacodynamics (PD), efficacy, safety, and to assess the performance of 266 mg EXPAREL vs 133 mg…
- Trial name
- NCT05157841
- Testing
- Bupivacaine liposome injectable suspension 266 mg, Bupivacaine HCl, Bupivacaine liposome injectable suspension 133 mg
- Where
- 7 sites in United States
- Volunteers
- 185 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Metatarsalgia
Operative Treatment Of Metatarsalgia: Triple Weil Osteotomy Or Distal Metatarsal Minimal Invasive Osteotomy (DMMO)?
INTRODUCTION Metatarsalgia is a vague term defining a symptom instead of a specific condition. The aim of surgical treatment of metatarsalgia is to decrease the pressure under metatarsal head, shortening and / or raising the…
- Trial name
- WeilvsDMMO (NCT02843672)
- Testing
- Triple Weil´s Osteotomy, Distal metatarsal minimally invasive osteotomy
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Manuel Cuervas-Mons
Constipation
Foot Reflexology and Abdominal Massage
to determine and compare the effects of foot reflexology and abdominal massage applied to elderly individuals on constipation
- Trial name
- experimental (NCT06875349)
- Testing
- foot reflexology, abdominal massage
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Karadeniz Technical University
Chronic Limb Threatening Ischemia
Clinical Outcomes Following Surgical Debridement of Diabetic Foot Infection with Borderline Vascularity
Observe Timing to complete healing of wounds \& Limb salvage in both cohorts those who are undergoing Debridement only and those who are undergoing Debridement plus PTA
- Trial name
- NCT05553509
- Testing
- PER CUTANEOUS TRANSLUMINAL ANGIOPLASTY
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Stroke, Ischemic
Aromatherapy and Foot Massage on Happiness, Sleep Quality, and Fatigue Levels of Patients With Stroke
Background: Stroke puts important economic and social loads on the society and was reported to be the most important reason for disability throughout the world.
- Trial name
- NCT05403515
- Testing
- foot massage, Foot massage +Aromatherapy group
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people
- Sponsor
- Osmaniye Korkut Ata University
Bunion, Post-operative Pain
CPL-01 in the Management of Postoperative Pain After Bunionectomy
Subjects receive study drug during bunionectomy and are followed for pain and opioid use, with the hypothesis that those who receive CPL-01 will have less pain and less opioid use than either control arm.
- Trial name
- NCT05831449
- Testing
- Local anesthetic injection of CPL-01, Naropin, 0.5% Injectable Solution, Morphine rescue medication
- Where
- United States
- Volunteers
- 616 people
- Sponsor
- Cali Pharmaceuticals LLC
CHRONIC POST-TRAUMATIC NEUROPATHIC PAIN IN ANKLE AND FOOT
Pilot RCT of Efficacy of Perineural Local Anesthetics and Steroids for Chronic Post-traumatic Ankle and Foot Pain
Injections of local anesthetics (freezing) and steroids are often performed around injured nerves in individuals with nerve injury-related pain.
- Trial name
- PREPLANS (NCT02680548)
- Testing
- 0.9% saline, 0.25% bupivacaine hydrochloride injectable suspension USP, 4mg/cc methylprednisolone acetate injectable suspension USP
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- University Health Network, Toronto
Musculoskeletal Pain
Effectiveness of Four Orthotic Insoles on Pain in the Lower Body Associated With Musculoskeletal Stress
This was an open-label, single-centre, parallel-group clinical investigation, to evaluate the effectiveness and in-use tolerability of a range of four orthotic insoles on target areas of pain in the lower body, associated with…
- Trial name
- NCT04746755
- Testing
- Orthotic Insole: Lower Back, Orthotic Insole: Heel, Orthotic Insole: Knee to Heel
- Where
- United Kingdom
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Heart Failure, Edema Leg
Foot Oedema Observed Over Time Study
Heart Failure is the final common pathway of most forms of cardiovascular disease. In the United Kingdom (UK), it affects around 900 000 people, causes or complicates around 5% of adult emergency hospital admissions and consumes…
- Trial name
- FOOT (NCT04072744)
- Testing
- Heartfelt measurements, Connected weighing scales
- Where
- 5 sites in United Kingdom
- Volunteers
- 31 people
- Sponsor
- Heartfelt Technologies
Hallux Valgus
Continuous Wound Infiltration After Hallux Valgus Surgery
The aim of this study is to investigate the effect of continuous wound infiltration with ropivacaine in comparison to standard pain management after elective distal metatarsal osteotomy for postoperative pain control.
- Trial name
- CWI-HVS (NCT02182999)
- Testing
- Wound infiltration catheter, NaCl 0.9%, Ropivacaine 0.2%
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University Innsbruck