Clinical trials: Foot Pathology
Tinea Pedis
Efficacy and Safety of NAFT-600 in Subjects With Tinea Pedis
The purpose of this study is to evaluate the efficacy and safety of NAFT-600, applied once daily for 2 weeks, when compared to placebo for 2 weeks in the treatment of subjects with tinea pedis.
- Trial name
- NAFT-600 (NCT01289015)
- Testing
- NAFT-600 ( naftin 2 % gel )
- Where
- 23 sites in United States, Puerto Rico
- Volunteers
- 855 people
- Sponsor
- Merz North America, Inc.
Hemiplegia, Stroke, Acute
Effects Of Sensory Training and Electrical Stimulation on Sole of The Foot Sensations in Patients With Acute Hemiplegia
The aim of this study is to investigate the effects of the sole of foot sensory education and electrical stimulation on proprioceptive and cortical senses in patients with acute hemiplegia.
- Conditions
- Hemiplegia, Stroke, Acute, Sensory Disorders
- Trial name
- NCT04252092
- Testing
- Sensory training, Electrical stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Yeditepe University
Haemophilic Arthropathy, Orthosis
Postural Assessment, Therapeutic Exercise and Orthotic Devices in the Prevention of Haemophilic Arthropathy
Haemophilic arthropathy (HA) is the most frequent complication of haemophilia and is often associated with a severe deterioration in quality of life.
- Conditions
- Haemophilic Arthropathy, Orthosis, Foot Malalignment
- Trial name
- NCT06438406
- Testing
- Orthotic devices and therapeutic exercise (Group A), Orthotic devices (Group B)
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University of Palermo
Breast Cancer, Colorectal Cancer
Celecoxib in Preventing Hand/Foot Syndrome Caused By Capecitabine With Metastatic Breast or Colorectal Cancer
RATIONALE: Radiation therapy uses high energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them…
- Conditions
- Breast Cancer, Colorectal Cancer, Pain
- Trial name
- NCT00305643
- Testing
- Capecitabine, Celecoxib, Radiation Therapy
- Where
- 14 sites in United States, Puerto Rico
- Volunteers
- 11 people
- Sponsor
- M.D. Anderson Cancer Center
Parkinson Disease
Foot Reflexology on Chronic Pain in Parkinsonian Patients
Pain is one of the non-motor symptoms of Parkinson's disease still poorly known and misdiagnosed and its management is complex. This encourage to explore new non-drug therapeutic paths, such as foot reflexology (FR).
- Trial name
- DOREPAR (NCT04705207)
- Testing
- reflexology massage
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Painful Intermetatarsal Neuroma (Morton's Neuroma)
A Study to Evaluate the Efficacy and Safety of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma)
Study 4975-MN-202 is a double-blind, placebo-controlled, parallel group, single-injection study in which subjects will be randomized to receive three doses of CNTX-4975 or placebo injected into the intermetatarsal space around a…
- Trial name
- NCT02283957
- Testing
- CNTX-4975
- Where
- 16 sites in United States
- Volunteers
- 119 people
- Sponsor
- Centrexion Therapeutics
Diabetic Foot Ulcers, Equinus Deformity
Determination of the Pathophysicologic Collagen Changes in the Diabetic Achilles Tendon
This is a pilot study examining tendon collagen, collagen cross-linking, and markers of tendon extracellular matrix metabolism in the Achilles tendon of diabetic patients with ulcerations and amputations of the lower extremity.
- Trial name
- NCT01382628
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Georgetown University
Premenstrual Syndrome
The Effect of Foot Bath on PMS, Sleep and Quality of Life Among University Students With PMS
Premenstrual syndrome is a cyclical disorder characterized by physical and emotional symptoms that appear in the late luteal phase of the menstrual cycle and subside within a few days with the onset of menstruation.
- Trial name
- NCT05264519
- Testing
- foot bath intervention
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Hüsne YÜCESOY
Postoperative Pain, Anxiety
Effects of Foot Reflexology on Postoperative Pain, Anxiety, Nausea, and Vomiting Among Patients After Laparoscopic Cholecystectomy
This study aims to evaluate the effect of foot reflexology on pain, anxiety, nausea, and vomiting among patients after laparoscopic cholecystectomy.
- Conditions
- Postoperative Pain, Anxiety, Nausea, Vomiting
- Trial name
- NCT07770295
- Testing
- Foot reflexology
- Where
- Egypt
- Volunteers
- 108 people
- Sponsor
- Ain Shams University
Diabetic Foot
Phase 2b Study of GAM501 in the Treatment of Diabetic Ulcers of the Lower Extremities
This is a Phase 2b, double-blind, randomized, placebo-controlled study to evaluate the safety and efficacy of one or two applications of topically applied GAM501 (Ad5PDGF-B/Bovine Type I Collagen Gel) in subjects ≥ 18 years old…
- Trial name
- MATRIX (NCT00493051)
- Testing
- GAM501, Standard of care
- Where
- 29 sites in United States
- Volunteers
- 124 people
- Sponsor
- Tissue Repair Company
Plantar Fasciitis, Plantar Heel Pain
Factors Affecting Response to Extracorporeal Shock Wave Therapy in Plantar Fasciitis: A Cross-sectional Clinical Study
Heel pain is a problem that affects daily life activities and quality of life. Extracorporeal shock wave therapy (ESWT) is a treatment used for heel pain. However, some people do not benefit from ESWT treatment.
- Trial name
- NCT07006389
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Low Back Pain
Lumbopelvic Stabilization Versus Pilates Exercises On Gait Phases And Peak Pressure On Foot In Low Back Pain
the purpose of this trial is to investigate and compare between lumbopelvic stabilization and pilates exercises on gait cycle phases and maximum peak pressure on the foot in chronic nonspecific low back pain?
- Trial name
- LBP (NCT04942782)
- Testing
- lumbopelvic stabilization exercises, pilates exercise, conventional therapy
- Volunteers
- 100 people
- Sponsor
- Cairo University
Diabetic Foot, Diabetic Foot Ulcer
SkinTE™ in the Treatment of Diabetic Foot Wounds
This study is a prospective, multi-center, randomized controlled trial designed to collect patient outcome data on a commercially available human autologous homologous skin construct with SOC dressing compared to SOC dressings…
- Conditions
- Diabetic Foot, Diabetic Foot Ulcer, Ulcer Foot
- Trial name
- NCT03881254
- Testing
- Human Autologous Homologous Skin Construct, Additional Outer Dressing Applicaiton, Offloading
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- PolarityTE
Hemiplegia, Cerebral Palsy
Motus Nova Foot Device for Patients With Hemiplegia
Individuals with hemiplegia commonly demonstrate gait deviations such as difficulties with heel strike at initial contact, foot drop in swing, asymmetrical limb loading, muscle activation, and balance impairments.
- Conditions
- Hemiplegia, Cerebral Palsy, Hemiplegic Cerebral Palsy
- Trial name
- NCT07754773
- Testing
- Motus Nova Foot
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- MultiCare Health System Research Institute
Blepharospasm, Hemifacial Spasm
Post Marketing Surveillance Study of Dysport
The purpose of this study is to provide further information regarding the risks and benefits of Dysport in marketed indications.
- Conditions
- Blepharospasm, Hemifacial Spasm, Cervical Dystonia, Spasmodic Torticollis
- Trial name
- NCT00210431
- Where
- 36 sites in France, Germany and 1 more
- Volunteers
- 783 people
- Sponsor
- Ipsen
Diabetic Foot Ulcer
The ASCEND Study: A Study to Investigate the Safety and Clinical Effect of Nexagon to Treat Slow Healing Diabetic Foot Ulcers
Diabetic foot ulcers are sores on the feet that occur in 15% of diabetic patients some time during their lifetime. Once an ulcer develops, the risk of lower-extremity amputation is increased 8-fold in people with diabetes.
- Trial name
- NCT00820703
- Testing
- Nexagon®, Nexagon® vehicle
- Where
- New Zealand
- Volunteers
- 24 people
- Sponsor
- OcuNexus Therapeutics, Inc.
Premenstrual Syndrome
Effects of Foot Bath Therapy on Premenstrual Syndrome Symptoms, Quality of Life, and Pain
The study was conducted as a randomized controlled trial to evaluate the effects of foot bath application on symptom severity, quality of life, and pain levels in women with premenstrual syndrome.
- Trial name
- NCT07461051
- Testing
- Foot bath therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Agri Ibrahim Cecen University
Postoperative Pain, Bunions
Evaluation of the Efficacy and Safety of Locally Administered HTX-011 for Postoperative Analgesia Following Bunionectomy
A Phase 2, Randomized, Controlled, Multicenter, Evaluation of the Efficacy and Safety of Locally Administered HTX-011 for Postoperative Analgesia Following Bunionectomy
- Trial name
- NCT02762929
- Testing
- HTX-011A, HTX-011B, HTX-002
- Where
- 5 sites in United States
- Volunteers
- 430 people
- Sponsor
- Heron Therapeutics
Knee Osteoarthritis, Foot Deformities
Muscle Architecture in Knee Osteoarthritis
Background: The aim of this study was to compare the knee and ankle muscle architecture and plantar pressure distribution differences in knee osteoarthritis (OA) women with healthy women.
- Conditions
- Knee Osteoarthritis, Foot Deformities, Muscle Weakness, Kinesiophobia
- Trial name
- NCT06319937
- Testing
- Ultrasound
- Volunteers
- 50 people
- Sponsor
- Hacettepe University
Craniosynostosis, Muenke Syndrome
Clinical Study of Muenke Syndrome (FGFR3-Related Craniosynostosis)
This study will explore the range and type of medical and developmental problems in patients with Muenke syndrome, a condition that results when one or more of the suture between the bones of the skull close before birth.
- Trial name
- NCT00106977
- Where
- 2 sites in United States
- Volunteers
- 137 people
- Sponsor
- National Human Genome Research Institute (NHGRI)