Clinical trials: Foot Pathology
Pes Planus, Flatfoot
Central Sensitization and Nociplastic Pain in Pes Planus
Background: Pes planus, commonly known as flatfoot, is a condition characterized by the collapse of the medial longitudinal arch of the foot.
- Conditions
- Pes Planus, Flatfoot, Central Sensitization, Nociplastic Pain
- Trial name
- NCT07125781
- Where
- Turkey (Türkiye)
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Bozok University
Ankle Injuries, Foot Injuries and Disorders
Weight Change With Controlled Ankle Movement (CAM) Boot Use
The purpose of the study is to determine if patients wearing a CAM boot have a change in weight compared to patients who wear a CAM boot and are provided nutritional guidelines and perform upper body exercises.
- Conditions
- Ankle Injuries, Foot Injuries and Disorders, Body Weight Changes
- Trial name
- CAM (NCT05692401)
- Testing
- Nutrition and Exercise Instruction
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Nell Blake, DPM
Massage, Labor Pain
The Effect of Foot Reflexology Massage on the Perception of Labor Pain in Nulliparous Pregnant Women
To evaluate the effect of reflexology massage, which is a non-pharmacological tool based on the effect of reflexology massage applied to the foot, on the perception of labor pain, on the perception of labor pain.
- Conditions
- Massage, Labor Pain, Foot Massage, Refleksoloji
- Trial name
- NCT07045675
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Atlas University
Cerebral Palsy
Shock Wave and Spastic Cerebral Palsy Equines Foot
A double-blind randomized controlled study was carried out on 34 children (19 boys and 15 girls) in the age ranged from 7 to 9 years old with spastic hemiplegia were randomly allocated to one of two groups: control or study…
- Trial name
- CP (NCT04835753)
- Testing
- shock wave, traditional physical therapy program
- Where
- Saudi Arabia
- Volunteers
- 34 people
- Sponsor
- Taibah University
Tinea Pedis, Athlete's Foot
Multicenter Study of the Safety and Efficacy of NAFT-500 in Tinea Pedis
A research study to compare the safety and effectiveness of an investigational medication called NAFT-500 to placebo, when used in subjects with tinea pedis (athlete's foot).
- Trial name
- NCT00750139
- Testing
- NAFT-500, Naftin 1%
- Where
- 17 sites in United States
- Volunteers
- 707 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Peripheral Arterial Disease(PAD), Arterial Occlusive Disease
Follow-up Study Using Gene Therapy for Critical Limb Ischemia (NL003-CLI-III-L)
The goal of this observational study is to learn about the long-term effects of Donaperminogene Seltoplasmid Injection (NL003) in participants who have been received drug NL003 or placebo at least one dose from the parent phase…
- Conditions
- Peripheral Arterial Disease(PAD), Arterial Occlusive Disease, Arteriosclerosis Obliterans, Thromboangiitis Obliterans
- Trial name
- NCT07023965
- Testing
- NL003
- Where
- 5 sites in China
- Volunteers
- 542 people
- Sponsor
- Beijing Northland Biotech. Co., Ltd.
Diabetes, Diabetic Foot Ulcer
The Mount Sinai Diabetic Foot Ulcer Prospective Trial
The purpose of this study is to evaluate whether placing stent(s) for a blockage in a leg vein will help improve the healing of diabetic foot ulcers (DFU).
- Conditions
- Diabetes, Diabetic Foot Ulcer, Edema
- Trial name
- NCT03404895
- Testing
- Conventional Therapy, Venous Stent(s)
- Where
- United States
- Sponsor
- Windsor Ting
Chronic Musculoskeletal Pain
Efficacy of the Transition of the Foot Strike Pattern on Pain and Disability in Cadets With Musculoskeletal Pain
To investigate the efficacy of the footstrike pattern transition from rearfoot to midfoot / forefoot pattern compared to lower limb muscle strengthening exercises and lumbar spine region on decreasing the intensity of chronic…
- Trial name
- NCT04166136
- Testing
- Transition from the Rearfoot to the Forefoot and Midfoot, Usual Treatment Group, Muscle Strengthening Group
- Where
- 2 sites in Brazil
- Volunteers
- 25 people
- Sponsor
- Centro Universitário Augusto Motta
Multiple Sclerosis
Effects of Targeted Lower Extremity Joint Training on Multiple Sclerosis (MS) Gait Abnormalities
This study is being done to test the possible benefits of task-specific focused ankle training using the Ankle-Bot on subjects with Multiple Sclerosis who have "foot-drop." The study also compares the effectiveness of…
- Trial name
- NCT00906737
- Testing
- Ankle-bot, Conventional focused ankle therapy
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Mount Sinai Rehabilitation Hospital
Diabetic Foot Ulcer, Coronary Artery Disease
Comparison of Imaging Quality Between Spectral Photon Counting Computed Tomography (SPCCT) and Dual Energy Computed Tomography (DECT)
This pilot study wants to determine to which extent SPCCT allows obtaining images with improved quality and diagnostic confidence when compared to standard Dual Energy CT (DECT), both with and without contrast agent injection.
- Conditions
- Diabetic Foot Ulcer, Coronary Artery Disease, Parenchymatous; Pneumonia, Kidney Stone
- Trial name
- SPEQUA (NCT04328181)
- Testing
- Spectral Photon Counting Computed Tomography (SPCCT), DECT (Dual Energy CT)
- Where
- France
- Volunteers
- 339 people
- Sponsor
- Hospices Civils de Lyon
Diabetic Polyneuropathy
Combined Effects of Foot-Ankle Therapeutic Exercises and Mindful Walking in Patients With Diabetic Polyneuropathy
The aim of this study is to investigate the combined effects of foot ankle therapeutic exercises and mindful walking on pain, foot and ankle disability, and quality of life in patients with diabetic polyneuropathy.
- Trial name
- NCT07248631
- Testing
- Foot-Ankle therapeutic exercises and Mindful Walking., Standard care with Mindful walking.
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Tinea Pedis
A Study to Evaluate Efficacy and Safety of Three W0027 Regimens in the Treatment of Moccasin Type Tinea Pedis (MTTP)
In this phase Ib, multi-centre, randomized, double-blind, placebo-controlled parallel group study, 120 subjects with moccasin type tinea pedis (MTTP) will be enrolled at approximately 11 centres in the USA, Canada and Australia.
- Trial name
- NCT00509275
- Testing
- W0027
- Where
- 9 sites in United States, Australia
- Volunteers
- 120 people
- Sponsor
- Stiefel, a GSK Company
Liposomal Bupivacaine, Postoperative Pain
Liposomal Bupivacaine Versus Bupivacaine Plain for Operative Pain Management of Forefoot Surgery
Prospective, randomized, controlled single-blinded trial comparing liposomal bupivacaine with bupivacaine HCl for postoperative management.
- Conditions
- Liposomal Bupivacaine, Postoperative Pain, Forefoot Surgery, Opioid Use
- Trial name
- NCT04751344
- Testing
- Liposomal bupivacaine, Bupivacaine HCl
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Alexandra Black
Surgical Pathology of the Leg or the Foot.
Pharmacokinetic of levobupivacaïne After Sciatic Nerve Block in Children
Levobupivacaïne (Chirocaine®) is a new local anaesthetic recently marketed in France. The goal of this prospective work is to study the pharmacokinetic aspect of this drug after injection around the sciatic nerve (subgluteal way).
- Trial name
- NCT00682344
- Testing
- Levobupivacaïne
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Tinea Pedis
Multicenter Study of the Efficacy and Safety of Luliconazole Cream in Tinea Pedis (Athlete's Foot)
To examine the safety and optimal duration of Luliconazole Cream 1% treatments for 14 days or 28 days to achieve "complete clearance" at 2 weeks post treatment.
- Trial name
- NCT00869336
- Testing
- Luliconazole Cream 1% - 2 wks, Luliconazole Cream 1% - 4 wks
- Where
- 4 sites in United States
- Volunteers
- 147 people
- Sponsor
- Tinea Pharmaceuticals
Pain, Post-operative
Evaluation of N1539 Following Bunionectomy Surgery
The primary objective of this study is to evaluate the analgesic efficacy of N1539 in subjects with acute moderate to severe pain following unilateral bunionectomy.
- Trial name
- NCT02675907
- Testing
- N1539
- Where
- 4 sites in United States
- Volunteers
- 201 people
- Sponsor
- Baudax Bio
Athlete Foot
Advanced Footwear Technology in Federated Athletes
Background. Athletics is one of the sports modalities with the greatest growth in the number of federative licenses in our country.
- Trial name
- NCT06919107
- Testing
- Survey of athletes
- Where
- Spain
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University of Oviedo
Pain, Post-operative
Placebo-Controlled Evaluation of N1539 Following Bunionectomy Surgery
The primary objective of this study is to evaluate the safety of N1539 in subjects with acute moderate to severe pain following unilateral bunionectomy.
- Trial name
- NCT02540265
- Testing
- N1539
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Baudax Bio
Plantar Fasciitis, Chronic, Pain
The Therapeutic Effect of Targeted Intrinsic Foot Muscles Exercises in Plantar Fasciitis
A reduction of intrinsic foot muscle sizes has been identified in patients with chronic plantar fasciitis. Weaker intrinsic foot muscles has been suggested to decrease the medial longitudinal arch height and subsequently increase…
- Trial name
- NCT05455645
- Testing
- targeted intrinsic foot muscle exercises
- Where
- Hong Kong
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Stroke, Gait, Hemiplegic
Effects of an Ankle-Foot Orthosis on Gait While Performing an Attention Demanding Task
We hypothesize that: (1) gait stability will be increased when wearing an ankle-foot orthosis (plastic brace supporting the foot and ankle); (2) an attention demanding task will decrease gait stability and (3) the improvement in…
- Trial name
- NCT01320839
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- Nova Scotia Health Authority