Clinical trials: Foot Pathology
Foot and Ankle Edema
Foot and Ankle Edema Post-Cesarean Delivery
Some women develop swollen feet and ankles after a cesarean delivery. These women will often complain that their shoes are too tight and their feet may become numb or they may have some tingling in their feet.
- Trial name
- NCT00488956
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- University of British Columbia
Foot Injuries and Disorders
SCANLOAD: The Effect of Limb Loading on Lower Limb Geometry
Orthotists currently use a range of weight bearing conditions when casting or scanning a patient's limb during the Ankle foot orthosis (AFO) fitting process.
- Trial name
- NCT04600102
- Testing
- Structure Sensor
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Iowa
Metatarsalgia
Randomized Controlled Trial of Custom Foot Orthoses for Chronic Forefoot Pain
Background Chronic metatarsalgia (CM) causes significant pain and disability, affecting quality of life. Foot orthoses (FOs) including medially wedged designs with a metatarsal pad decrease excessive plantar pressure under the…
- Trial name
- NCT06962475
- Testing
- Podiatric advice, Customized foot orthoses
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- Université du Québec à Trois-Rivières
Hand, Foot and Mouth Disease
Chinese Medicinal Treatment on Mild Hand, Foot, and Mouth Disease: Multicenter, Prospective, Randomized Double-blind, Placebo-controlled Study
The study is aimed to evaluate the effectiveness and safety of Jinlianqingre Effervescent Tablets, a traditional Chinese medicine (TCM), in the treatment of Uncomplicated hand, foot, and mouth disease (HFMD).
- Trial name
- NCT01769794
- Testing
- Western therapy, JET
- Where
- 4 sites in China
- Volunteers
- 288 people
- Sponsor
- China Academy of Chinese Medical Sciences
Post-Stroke Spasticity, Spastic Equinovarus Foot
Efficacy of Focused Shock Wave Therapy Before and After Botulinum Toxin Injection in Patients With Post-Stroke Spastic Equinus/Equinovarus Foot: A Randomized Clinical Trial
Spastic equinovarus foot is the most common lower limb motor impairment after stroke and has a significant impact on gait, mobility, and quality of life.
- Trial name
- NCT07758322
- Testing
- Botulinum toxin type A, Focal Extracorporeal Shock Wave Therapy (ESWT)
- Where
- Spain
- Volunteers
- 69 people
- Sponsor
- María Belén Martínez Luna
Diabetic Foot Ulcer Associated With Type II Diabetes Mellitus
Effect of Stress Ball Applied During Surgical Debridement/Dressing on Pain, Distress, and Physiological Parameters in Patients With Diabetic Foot Ulcers
Diabetes mellitus (DM) is a common metabolic disease characterized by hyperglycemia, resulting from a deficiency or insufficiency of insulin.
- Trial name
- NCT07119983
- Testing
- Stress ball
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Cukurova University
Cerebrovascular Accident
Botulinum Toxin Injections by Ultrasounds Guidance and Stretching Exercise in Spastic Toe Clawing
Claw toes deformity result in spasticity often seem in patients with central nerve disease. It also cause pressure sore in foot and pain during walking that didn't well improve under traditional treatment.
- Trial name
- NCT02586142
- Testing
- Botulinum Toxin Type A, Stretching exercise
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Chang Gung Memorial Hospital
Narcotic Consumption, Pain
Motorized Continuous Cold Therapy Versus Standard Post-op Icing Protocol for Two Foot and Ankle Procedures
This study will compares differences in pain level, narcotic consumption, wound healing, patient satisfaction in patients randomized to the Iceman® cold pack therapy system (djOrtho, Inc) versus those who use ice.
- Conditions
- Narcotic Consumption, Pain, Wound Healing, Patient Satisfaction
- Trial name
- NCT00950183
- Testing
- Iceman® Cold Therapy unit (djOrtho), Ice
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Foot Ulcer, Diabetic
Clinical Trial to Evaluate the Efficacy and Safety of Sodium Bemiparin for Treatment of Diabetic Foot Ulcers
Chronic foot ulcers are a common, severe and expensive complication in patients with diabetes and often causes lower-extremity amputation.
- Trial name
- NCT00448903
- Testing
- Bemiparin
- Where
- 6 sites in Croatia, Poland and 4 more
- Volunteers
- 329 people
- Sponsor
- Rovi Pharmaceuticals Laboratories
Ulcers Related to Diabetic Foot Syndrome
Safety and Efficacy Study of Neovasculgen (Pl-VEGF165) Gene Therapy in Patients With Diabetic Foot
The purpose of this study is to determine whether pl-vegf165 (Neovasculgen) is effective in the treatment of ulcers related to diabetic foot syndrome
- Trial name
- NCT02538705
- Testing
- Neovasculgen
- Where
- Russia
- Volunteers
- 35 people
- Sponsor
- Artgen Biotech
Episiotomy
Effect of Foot Reflexology on Perineal Pain, Fatigue and Healing Quality in Primiparous Patients Undergoing Episiotomy
The act of giving birth can expose women to many risks during pregnancy and the birth process. It causes long-term emotional problems in pregnant women who experience labor pain and negatively affects their mental health.
- Trial name
- NCT06955507
- Testing
- reflexology
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Diabetic Foot Ulcer
Nitric Oxide Generating Gel Dressing in Patients With Diabetic Foot Ulcers
This is a 2 part study to assess the safety and efficacy of a nitric oxide (NOx) generating dressing on chronic diabetic foot ulcers (DFU). Nitric oxide has a range of effects on the body including vasodilation and angiogenesis.
- Trial name
- ProNOx1 (NCT01982565)
- Testing
- NOx dressing, Standard of Care
- Where
- 10 sites in United Kingdom
- Volunteers
- 130 people
- Sponsor
- Edixomed Ltd
Diabetic Foot Disease, Recurrence
Better Care Closer to Home: Enhancing Primary and Community Care
60 million people in Europe have diabetes (DM) and up to 34% (20.4 million) of them are at risk of developing diabetic foot ulcers (DFUs) in their lifetime (1).
- Trial name
- NCT07905664
- Testing
- Path Active™, a smart insole system designed to reduce the risk of plantar ulceration in patients with diabetic foot disease
- Where
- 3 sites in Canada, Denmark and 1 more
- Volunteers
- 84 people
- Sponsor
- Universidad Complutense de Madrid
Leg Ulcer, Diabetic Foot
Autologous Transplantation of BM-ECs With Platelet-Rich Plasma Extract for the Treatment of Critical Limb Ischemia
The intent of this clinical study is to evaluate the safety of the injection composed of autologous bone marrow derived endothelial cells (BM-ECs) and platelet-rich plasma extract (PRPE) for the treatment of critical limb…
- Conditions
- Leg Ulcer, Diabetic Foot, Gangrene, Peripheral Vascular Disease
- Trial name
- NCT02993809
- Testing
- BM-ECs and PRPE, BM-ECs
- Volunteers
- 40 people
- Sponsor
- South China Research Center for Stem Cell and Regenerative Medicine
Flat Foot; Spastic
To Evaluate the Efficiency and Results of Adding BFR to the Physical Therapy Program fo Managing Adolescents Presented With Spasmotic Flatfoot Deformities Compared to the Standard Physical Therapy Program Without BFR
The goal of this randomized clinical trial is to evaluate the efficiency and results of adding blood flow restriction (BFR) training to the physical therapy program for managing adolescents presented with spasmotic flatfoot…
- Trial name
- BFR SFFD (NCT07343752)
- Testing
- blood flow restriction
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Accidental Falls, Fall Due to Loss of Equilibrium
OHI--Randomized Control Trial to Evaluate Efficacy, Acceptability, and Perception of Benefit of an Innovative Custom AFO
The investigators propose a randomized control trial to evaluate long term effects and effectiveness of Moore Balance Brace (MBB) ankle foot orthoses (AFO) in reducing risk of falling in older adults.
- Conditions
- Accidental Falls, Fall Due to Loss of Equilibrium, High Risk of Falls Due to Mobility Limitation, Diabetes
- Trial name
- NCT02819011
- Testing
- MBB AFO, Control
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Bijan Najafi, PhD
Tinea Pedis
Efficacy and Safety of Terbinafine Film Forming Solution in Patients With Tinea Pedis
This study will compare the efficacy and safety of a single dose of terbinafine film forming solution 1% with a single dose of placebo film forming solution in the treatment of tinea pedis.
- Trial name
- NCT01433107
- Testing
- Terbinafine
- Where
- 6 sites in China
- Volunteers
- 290 people
- Sponsor
- Novartis
Foot Injuries and Disorders, Balance; Distorted
Comparing the Effects of Foot Core Exercises
The purpose of the study was to compare the effects of towel curl exercises and short foot exercises on pedobarographic parameters and balance.
- Trial name
- NCT04264611
- Testing
- Experimental: Short Foot Exercise Group, Experimental: Towel Curl Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Lokman Hekim University
Onychomycosis, Tinea Pedis
Spread of Dermatophytes Among Families
The objective is to demonstrate person-to-person spread of dermatophytes of the skin and nails among family members, as measured by fungal culture and DNA typing of the dermatophytes isolated.
- Trial name
- NCT00233493
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Postpartum Disorder, Massage
Effect of Foot Massage on Postpartum Comfort and Pain Level of the Mothers Who Had Vaginal Birth
Background and Purpose: This study aims to investigate the effect of foot massage in the postpartum period on the need of receiving analgesic medication after assessing the postpartum comfort and pain status of the mothers who…
- Trial name
- NCT04037202
- Testing
- Foot massage
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ege University