Clinical trials: Foot Pathology
Painful Diabetic Neuropathies
Safety and Efficacy Study for the Treatment of Painful Diabetic Neuropathy
The purpose of this study is to determine if Engensis (VM202) is safe and effective in treating painful diabetic neuropathy.
- Trial name
- NCT01475786
- Testing
- Low Dose: 16 mg Engensis (VM202), High Dose: 32 mg Engensis (VM202)
- Where
- 17 sites in United States, South Korea
- Volunteers
- 104 people
- Sponsor
- Helixmith Co., Ltd.
Plantar Fasciitis, Chronic
A Novel Approach to Plantar Fasciitis in the Aging Population
The goal of this study is to determine whether improving foot strength through foot exercises and minimal footwear can provide improved outcomes over the short and long term.
- Trial name
- NAPA (NCT05834491)
- Testing
- minimal shoes and foot strengthening and flexibility exercises, Supportive Footwear, foot orthotic device and foot flexibility exercises
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- University of South Florida
Musculoskeletal Pain, Musculoskeletal Injury
The Diagnostic Accuracy of the Clinical Examination
This study examines the diagnostic accuracy of the clinical examination as compared to MRI findings
- Trial name
- NCT03850470
- Testing
- clinical examination, MRI
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- High Point University
Foot and Ankle Procedures
Efficacy of Popliteal Nerve Blocks With and Without Dexamethasone on the Duration of Analgesia for Foot & Ankle Surgery
The purpose of this research study to evaluate the effects of dexamethasone as an addition to peripheral nerve block (Put the nerve to sleep with Bupivacaine a numbing medication) on length of pain relief (analgesia)…
- Trial name
- NCT01975285
- Testing
- Dexamethasone, Saline
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Cedars-Sinai Medical Center
Gait, Drop Foot
Comparison of Conventionally Manufactured AFO and Modular Customized AFO
The Investigator will investigate the difference in the gait pattern between 2 commercially available ankle foot orthoses (AFO): a) conventionally manufactured AFO and b) modular customized AFO using Industry 4.0 technology.
- Trial name
- AFO4-0 (NCT05192915)
- Testing
- Modular customized AFO
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- Beat Göpfert
Diabetes, Visual Impairment
Nonvisual Foot Inspection for People With Visual Impairment
The purpose of this study was to find out whether a method of nonvisual foot inspection, using the senses of touch and smell, helps people with diabetes and visual impairment to find new foot problems when they are in early…
- Trial name
- NCT01822717
- Testing
- Nonvisual foot inspection, Usual Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Case Western Reserve University
Critical Limb Ischemia
Peri-operative Foot CT Perfusion in CLI Patients
To investigate the clinical value of quantitative analysis of peri-operative foot supply through CT perfusion in patients with critical limb ischemia
- Trial name
- POP-CLI (NCT05575778)
- Testing
- computed tomographic perfusion
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Fudan University
Ulcer, Venous Ulcer
ECM and Blood Components for Wound Healing
The Extracellular Matrix (ECM) and Blood Components for Wound Healing feasibility study is a clinical trial approved by Health Canada to study the safety of extracellular matrix (ECM) and autologous blood products in wound…
- Conditions
- Ulcer, Venous Ulcer, Foot Ulcer, Diabetic
- Trial name
- NCT01909908
- Testing
- ECM, Blood Products, ECM in Blood Products
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- Cook Group Incorporated
Menopausal Women
Foot Massage for Women With Menopause
This study will be carried out to determine the effect of foot massage applied to menopausal women on anxiety, fatigue and sleep levels.
- Trial name
- NCT05212376
- Testing
- Foot massage
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Inonu University
Post-surgical Pain, Total Knee Arthroplasty
Effects of Catheter Location on Postoperative Analgesia for Continuous Adductor Canal and Popliteal-Sciatic Nerve Blocks
Currently, continuous adductor canal and popliteal-sciatic nerve blocks are used commonly for lower extremity post-operative pain control, specifically for total knee arthroplasty and foot/ankle surgery, respectively.
- Conditions
- Post-surgical Pain, Total Knee Arthroplasty, Foot/Ankle Surgery, Catheterization for Postop Analgesia
- Trial name
- NCT02523235
- Testing
- ropivacaine 0.2%
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- University of California, San Diego
Tinea Pedis
Evaluate Safety and Efficacy of Naftifine Hydrochloride Gel 2% and Naftin® Gel 2% in Tinea Pedis
To compare the efficacy and safety of the test formulation Naftifine Hydrochloride Gel 2% to Naftin® (Naftifine Hydrochloride) Gel 2%
- Trial name
- NCT02335255
- Testing
- Naftifine Hydrochloride Gel 2%, Naftin® Gel 2%
- Volunteers
- 1,519 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Gait, Drop Foot, Chemotherapy-induced Peripheral Neuropathy
Impact of an Orthotic Intervention in Children With Peripheral Neuropathy
This research study will investigate the effect of two orthotic (brace) devices for the ankle and foot on walking and ankle flexibility in children with cancer not involving the brain or spinal cord.
- Conditions
- Gait, Drop Foot, Chemotherapy-induced Peripheral Neuropathy, Acute Lymphocytic Leukemia, Pediatric, Rhabdomyosarcoma
- Trial name
- IOPN (NCT03655587)
- Testing
- Solid ankle foot orthotic, Resting night splint
- Where
- 2 sites in United States
- Volunteers
- 27 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Diabetes Mellitus, Type 2
Propolis as Adjuvant in the Healing of Human Diabetic Foot Wounds
The general objective of the project is "To evaluate the effect of the administration of propolis extract as a coadjuvant in the treatment of diabetic foot ulcers in patients receiving cures in the Specialties Polyclinic of the…
- Trial name
- NCT03649243
- Testing
- Propolis spray
- Volunteers
- 31 people
- Sponsor
- University of Talca
Ledderhose Disease
Ledderhose Disease - Long Term Effects of Radiotherapy Treatment. LedRad LTE - Study
The aim of the LedRad LTE study is to determine the current complaints, late side effects and satisfaction of patients who were treated with radiotherapy for Ledderhose disease at least two years ago.
- Trial name
- NCT04229147
- Testing
- Radiotherapy
- Where
- Netherlands
- Volunteers
- 68 people
- Sponsor
- University Medical Center Groningen
Lupus Erythematosus, Systemic, Foot Orthoses
Effect of Insoles in Patients With Systemic Lupus Erythematosus
Demonstrate that custom-made insoles improve painful symptomatology, health and foot function in subjects with SLE and podiatric involvement.
- Conditions
- Lupus Erythematosus, Systemic, Foot Orthoses, Musculoskeletal Pain
- Trial name
- EISLE (NCT04098055)
- Testing
- Custom-Made Foot Orthoses
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- University of Seville
Postoperative Pain
Catheter-based Peripheral Regional Anesthesia After Orthopedic Surgery to the Foot or Ankle
BACKGROUND Orthopedic surgery can be severely painful, and peripheral regional anesthesia is highly recommended as part of the perioperative pain treatment.
- Trial name
- API-FOOT (NCT03372304)
- Testing
- Ropivacaine 0.2%
- Where
- Denmark
- Volunteers
- 85 people
- Sponsor
- Nordsjaellands Hospital
Hernia, Inguinal, Flat Foot
The Efficacy and Safety of Chloroprocaine 1% and 2% in Pediatric Population
Randomized, multi-center, double-blind, two-armed, parallel active groups, prospective trial to evaluate the efficacy and safety of local anesthetic Chloroprocaine at two different concentrations ( at 1% and 2%) in a pediatric…
- Trial name
- NCT03918798
- Testing
- Chloroprocaine 1% Injectable Solution, Chloroprocaine 2% Injectable Solution
- Where
- 9 sites in Italy, Spain
- Volunteers
- 164 people
- Sponsor
- Sintetica SA
Foot Drop, Stroke
Ankle Robotics After Stroke
The randomized study (in Phase II of the U44) compares the efficacy and durability of 9 weeks (18 sessions) of robot-assisted physical therapy (PTR) versus physical therapy (PT) alone on foot drop as assessed by gait biomechanics…
- Conditions
- Foot Drop, Stroke, Hemiparesis
- Trial name
- NCT04594837
- Testing
- PTR Physical Therapy while wearing Robot group (Phase II), Physical Therapy Only (Phase II), Cross over group for Physical Therapy n Sub-Acute group. (Phase II)
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- NextStep Robotics Inc.
Foot Injuries and Disorders
Ankle Foot Orthosis Comparative Effect
The proposed effort is designed to support evidence-based practice and optimal care by evaluating how the form, fit and function of two commercially available carbon fiber custom fit braces (Orthoses) influences outcomes…
- Trial name
- AFOCE (NCT03901053)
- Testing
- Reaktiv AFO, PhatBrace AFO
- Where
- 3 sites in United States
- Volunteers
- 54 people
- Sponsor
- Jason Wilken
Athletes Foot
Curcuma Extract Beneficial for Muscle Damage
Muscle damage and inflammation is a clinical problem caused by the unimpeachable body adaptation of strenuous exercise through increasing free radicals.
- Trial name
- NCT04439981
- Testing
- Ice cream
- Where
- Indonesia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitas Muhammadiyah Semarang