Clinical trials: Foot Ulcer, Diabetic
Diabetic Foot Ulcer, Venous Leg Ulcer
PLASOMA Ultimate Safety & Efficacy Study
The purpose of the PULSE study are the followingL A.To perform post market clinical follow up (PMCF) on safety and efficacy: 1. Safety: To confirm transient short-terms side effects and verify long-term/outstanding risks. 2.
- Conditions
- Diabetic Foot Ulcer, Venous Leg Ulcer, Pressure Ulcer, Burn Wound
- Trial name
- PULSE (NCT04828304)
- Testing
- PLASOMA
- Where
- 6 sites in Netherlands
- Volunteers
- 101 people
- Sponsor
- Plasmacure
Foot Ulcer, Diabetic
GrafixPRIME® for the Treatment of Chronic Diabetic Foot Ulcers
The objective of the study is to compare the efficacy of weekly GrafixPRIME® administration to an Active Comparator in patients with chronic DFUs in a randomized, single-blind study.
- Trial name
- NCT02675855
- Testing
- GrafixPRIME®, Dressing Application, Off-loading (walking boot)
- Where
- 3 sites in United States
- Volunteers
- 75 people
- Sponsor
- Osiris Therapeutics
Diabetic Foot Ulcer
The Effect of Breathing Exercise and Pressurized Cold Application on Pain and Anxiety During Sharp Debridement
In our planned study, it is envisaged that patients who receive breathing exercises and pressurized cold application will experience a decrease in the level of pain they feel during the debridement process, a decrease in their…
- Trial name
- NCT06886633
- Testing
- Breathing exercise, Experimental: Pressurized Cold Application Group
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Harran University
Diabetic Foot Ulcer
The Effect of Implementing a Limb Loss Prevention Program on Amputation Rates
The investigators plan to do a retrospective chart review on patients admitted to Parkland Hospital with diabetic foot infections, ulcers, and bone injuries from 2005 (5 years prior to the start of the diabetic limb preservation…
- Trial name
- NCT03978715
- Testing
- No intervention-retrospective study
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- University of Texas Southwestern Medical Center
Diabetic Foot Ulcer, Diabetic Foot Infection
Randomized Double-Blind Trial on Safety and Efficacy of Nanordica Advanced Antibacterial Wound Dressing for Diabetic Foot Ulcer
This clinical trial evaluates the safety and efficacy of the Nanordica Advanced Antibacterial Wound Dressing (AAWD) in patients suffering from diabetic foot ulcers.
- Trial name
- NM2023 (NCT06667752)
- Testing
- Advanced Antibacterial Wound Dressing, Aquacel Ag+ Extra
- Where
- 11 sites in Estonia, Spain
- Volunteers
- 136 people
- Sponsor
- Nanordica Medical OU
Diabetic Foot Ulcer
Effectiveness of a Digital Health Education on Self-Foot Care and Quality of Life Among Patients With Diabetes
Diabetes is a significant global health concern, affecting over half a billion people and leading to severe complications like diabetic foot ulcers (DFUs).
- Trial name
- NCT06538168
- Testing
- Diabetes Self-Management Education (DSME)
- Volunteers
- 2,430 people
- Sponsor
- Universiti Putra Malaysia
Diabetic Foot Ulcer
Clinical Trial Evaluating the Safety and Efficacy of the Use of Chitosan Gel in Patients With Chronic Wounds
Type 1 and Type 2 diabetic patients with diabetic foot ulcer will be recruited and screened for participation in the study. Eligible patients will be randomized 1:1 to either experimental or control group and undergo 10-weeks of…
- Trial name
- CHITOWOUND (NCT04178525)
- Testing
- ChitoCare gel
- Where
- 5 sites in Croatia, Slovenia
- Volunteers
- 46 people
- Sponsor
- Primex ehf
Wound Heal
Impact of Cilostazol Versus Cilostazol and Selenium Combination on the Healing of Diabetic Foot Ulcer Patients
The growing incidence of DM can lead to the increased prevalence of diabetic foot complications, which have become a serious medical, social, and economic concern of global importance.
- Trial name
- NCT06117436
- Testing
- Cilostazol, Selenium
- Where
- Egypt
- Volunteers
- 206 people
- Sponsor
- Ain Shams University
Diabetic Foot Ulcer
Phase 2a Multi-Center Prospective, Randomized Trial to Evaluate the Safety & Efficacy of Topical PEP-TISSEEL for Diabetic Foot Ulcers (DFU)
This is a Phase 2a Multi-Center, Prospective, Randomized, Controlled Study aimed to evaluate the Safety and Efficacy of Topically Applied PEP-TISSEEL in Subjects with Diabetic Foot Ulcers (DFU)
- Trial name
- NCT06319287
- Testing
- PEP (Purified Exosome Product) / TISSEEL
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Rion Inc.
Diabetes, Neuropathic Foot
A Comparison of Insoles Used to Prevent Neuropathic Diabetic Foot Ulceration
Importance of the topic: Lower extremity amputation is a costly complication of diabetes for both the NHS and the patient. Amputation may be avoided if the preceding foot ulceration can be prevented.
- Trial name
- NCT00999635
- Testing
- Insole
- Where
- 2 sites in United Kingdom
- Volunteers
- 119 people
- Sponsor
- University of Plymouth
Diabetic Foot Ulcer
Clinical Study to Evaluate Efficacy and Safety of ALLO-ASC-DFU in Patients With Diabetic Wagner Grade 2 Foot Ulcers.
This is a phase III double-blind study to evaluate the efficacy and safety of ALLO-ASC-DFU in patients with Diabetic Wagner grade 2 Foot Ulcer, compared to placebo therapy.
- Trial name
- NCT04569409
- Testing
- ALLO-ASC-DFU, Vehicle Sheet
- Where
- 5 sites in South Korea
- Volunteers
- 104 people
- Sponsor
- Anterogen Co., Ltd.
Diabetes Mellitus, Diabetic Foot Ulcer
Online Diabetic Foot Support Program- Care Kit
The aim of this project is to examine the effects of the online diabetic foot support program (DiaFootSuP) and care kit applied to type 2 diabetic individuals who have previously had a diabetic foot ulcer on diabetic foot…
- Conditions
- Diabetes Mellitus, Diabetic Foot Ulcer, Diabetic Foot
- Trial name
- DiaFootSuP (NCT06760416)
- Testing
- Nursing Education
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Merve GÃnbaAY
Diabetic Foot
Wound Bed Preparation for Diabetic Foot Ulcers
The study objective was to compare the efficacy of NPWT versus alginates dressings on the wound bed preparation prior to STSG surgery, as well as investigating the underlying mechanisms.
- Trial name
- NCT05577104
- Testing
- Negative pressure wound therapy (NPWT), conventional moist dressings
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Diabetic Foot Ulcer
Use of Extracellular Vesicles (EV) for Diabetic Foot Ulcers
Diabetes Mellitus is a common chronic medical condition that requires complex care strategies. Treatment includes methods to reduce glycemic burden and maintain glycemic control in the patient to prevent symptoms of hyperglycemia…
- Trial name
- EVDFUUJCTC (NCT06825884)
- Testing
- Extracellular micro vesicles (EV)
- Where
- Jordan
- Volunteers
- 10 people
- Sponsor
- University of Jordan
Diabetic Foot Ulcer
Trial to Evaluate the Safety and Effectiveness of Treatment With COMS One Device in Subjects With Diabetic Foot Ulcers
The purpose of this clinical trial is to evaluate the safety and effectiveness of the treatment with the COMS One device in subjects with refractory diabetic foot ulcers (DFUs).
- Trial name
- Mavericks (NCT05758545)
- Testing
- COMS One device
- Where
- 30 sites in United States
- Volunteers
- 450 people
- Sponsor
- Piomic Medical
Diabetes Mellitus Foot Ulcer, Diabetes Mellitus, Type 2
Diabetes Footcare Companion App for Patients and Carers
Diabetes education and self-management support can be delivered via mobile phones. This protocol aims to assess the feasibility and acceptability of Well Feet, a conversational agent, as a diabetic foot care companion.
- Conditions
- Diabetes Mellitus Foot Ulcer, Diabetes Mellitus, Type 2, Diabetic Foot, Diabetic Foot Infection
- Trial name
- NCT05564728
- Testing
- Conversational Agent/Chatbot App
- Where
- 2 sites in Singapore
- Volunteers
- 40 people
- Sponsor
- Nanyang Technological University
Diabetic Foot Ulcer
Clinical Outcomes After Treatment With RestrataTM Wound Matrix in Diabetic Foot Ulcers (DFU)
The primary objective of this study is to determine the outcomes of patients who receive a certain type of skin substitute called RestrataTM Wound Matrix (Restrata™).
- Trial name
- NCT03312595
- Testing
- Restrata TM Wound Matrix
- Where
- 5 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Acera Surgical, Inc.
Neuropathic Diabetic Ulcer - Foot
Safety Trial of the RedDress Wound Care System (RD1) in Management of Texas 1a or 2a Neuropathic Diabetic Foot Ulcers.
The purpose of this study is to assess the safety of the RedDress Wound Care System (RD1) in patients Texas 1a or 2a Neuropathic Diabetic Foot Ulcers.
- Trial name
- NCT01396837
- Testing
- RedDress Wound Care System (RD1)
- Where
- 4 sites in United States
- Volunteers
- 20 people
- Sponsor
- RedDress Ltd.
Diabetic Foot Ulcer
RCT Comparing Upper Body vs. Combined Exercise Protocols During Active Diabetic Foot Ulcer Treatment
This randomized controlled trial (RCT) aims to evaluate the effectiveness of two different structured exercise interventions compared to standard care during active diabetic foot ulcer (DFU) treatment.
- Trial name
- NCT06916663
- Testing
- Upper Body Exercise Protocol (UBE), Combined Non-Weight Bearing Exercise Protocol (CE), Standard Diabetic Foot Ulcer Wound Care (SC)
- Where
- Egypt
- Volunteers
- 153 people
- Sponsor
- Al Hayah University In Cairo
Infection; Diabetic Foot
Ertapenem Sodium (MK-0826) Versus Piperacillin/Tazobactam Sodium for the Treatment of Diabetic Foot Infections in Chinese Adults (MK-0826-061)
This study compared ertapenem sodium to piperacillin/tazobactam sodium for the treatment of moderate to severe diabetic foot infections.
- Trial name
- NCT01370616
- Testing
- Ertapenem sodium, Piperacillin/tazobactam sodium, Amoxicillin/clavulunate potassium
- Volunteers
- 565 people
- Sponsor
- Merck Sharp & Dohme LLC