Clinical trials: For Intervention
Asthma
Asthma Intervention Research (AIR) Trial
The purpose of this study is to demonstrate the effectiveness and safety of the Alair System for the treatment of asthma. This will be a multicenter, randomized controlled study comparing the effects of treatment with the Alair…
- Trial name
- NCT00214526
- Testing
- Bronchial thermoplasty with the Alair System, Conventional therapy with ICS+LABA
- Volunteers
- 112 people
- Sponsor
- Asthmatx, Inc.
Hyperammonemia, Methylmalonic Acidemia
An Observational Study of Carbaglu® for the Treatment of MMA and PA in Adults and Pediatrics
To obtain short-term and long-term clinical safety information, in pediatric and adult patients with PA and MMA treated with Carbaglu®.
- Conditions
- Hyperammonemia, Methylmalonic Acidemia, Propionic Acidemia
- Trial name
- NCT05040178
- Testing
- Carglumic Acid
- Where
- 5 sites in United States
- Volunteers
- 20 people
- Sponsor
- RECORDATI GROUP
Mental Health, Neurodevelomental Disorders
Mental Health and Innovation for French Higher-education Students
To fully grasp mental health, it is essential to understand and assess it by considering all the factors that affect it: family environment, school environment, emotional relationships, living conditions, social networks, etc.
- Trial name
- SMILE (NCT07800585)
- Where
- France
- Volunteers
- 13,710 people, healthy volunteers welcome
- Sponsor
- O-Kidia
Diabetes Mellitus, Type 2
A German Study Evaluating the Efficacy and the Benefit of Integrated Personalized Diabetes Management (PDM) for Type 2 Diabetes Patients.
This study is a German, prospective, multicenter, controlled, cluster-randomized, interventional comparative study evaluating the efficacy and benefits of integrated PDM care by measuring HbA1c levels in patients with Type 2…
- Trial name
- PDM-ProValueGP (NCT02268929)
- Testing
- Accu-Chek Smart Pix Software, Accu-Chek Smart Pix readout Device
- Where
- 50 sites in Germany
- Volunteers
- 414 people
- Sponsor
- Hoffmann-La Roche
Chronic Obstructive Pulmonary Disease (COPD)
Targeted Lung Denervation for Patients With Moderate to Severe COPD
The purpose of this study is to evaluate safety of Targeted Lung Denervation (or TLD) in patients suffering from moderate to severe COPD.
- Trial name
- AIRFLOW (NCT02058459)
- Testing
- Holaira™ Lung Denervation System with energy delivery, Holaira™ Lung Denervation System without energy delivery
- Where
- 18 sites in Austria, Belgium and 4 more
- Volunteers
- 128 people
- Sponsor
- Nuvaira, Inc.
Coronary Artery Disease, Myocardial Ischemia
BIOFLOW-III Canada Satellite Registry
For the majority of Coronary Artery Disease (CAD), treatment with Percutaneous Transluminal Coronary Angioplasty (PTCA) provides high initial procedural success.
- Trial name
- NCT01880242
- Where
- 2 sites in Canada
- Volunteers
- 250 people
- Sponsor
- Biotronik Canada Inc
Pulmonary Fibrosis
Non-Interventional Study (NIS) Collecting Experiences For IPF in Taiwan
This is a non-interventional, multi-center study to collect data from patients with idiopathic pulmonary fibrosis (IPF) in clinical practice in Taiwan.
- Trial name
- NCT03242759
- Testing
- nintedanib, pirfenidone
- Where
- 10 sites in Taiwan
- Volunteers
- 101 people
- Sponsor
- Boehringer Ingelheim
CT-guided Minimally Invasive Procedures e.g., Biopsies
Evaluation of the Safety, Effectiveness & Usability of the XACT Robotic System for Image Guided Percutaneous Procedures
This is a prospective, single-arm study is to evaluate the safety, effectiveness and usability of the XACT device. Subjects undergoing CT-guided, minimally invasive percutaneous procedures in the interventional radiology suite…
- Trial name
- NCT03008603
- Testing
- XACT Robotic System
- Where
- 2 sites in United States, Israel
- Volunteers
- 60 people
- Sponsor
- Xact Robotics Ltd.
Anemia, Blood Transfusion
A Study to Determine Whether Epoetin Alfa Can Reduce the Need for Blood Transfusions in Patients During the Period of Time Around Major Orthopedic Surgery.
The purpose of this study is to evaluate the safety of epoetin alfa and to determine whether epoetin alfa will reduce the need for blood transfusions during the period of time around major orthopedic surgery.
- Conditions
- Anemia, Blood Transfusion, Orthopedic Procedures
- Trial name
- NCT00270088
- Testing
- epoetin alfa
- Volunteers
- 316 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Aesthetics Procedure
Post-market Study on BtHCROSS® for Restoring Facial Volume After a Single Injection
This clinical study investigated the safety and effectiveness of BtHCROSS, a hyaluronic acid-based injectable used to restore facial volume and reduce wrinkles.
- Trial name
- NCT07301619
- Testing
- BtHCROSS®
- Where
- Spain
- Volunteers
- 203 people
- Sponsor
- i+Med S.Coop.
Depression, Anxiety
Understanding the Efficacy of Mobile Apps as Intervention for Depression in Adults When Deployed as Part of Primary Care.
The clinical study is meant to optimize the mobile intervention, to develop a robust implementation plan for the mobile intervention within primary care, and to conduct an effectiveness trial, randomizing 128 participants in…
- Conditions
- Depression, Anxiety, Primary Health Care
- Trial name
- NCT03500536
- Testing
- IntelliCare
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Actualize Therapy
Skin Hydration, Skin Elasticity
Efficacy and Safety of PN+HA (NEWEST) for the Improvement of Skin Hydration
This is a post-market, monocentric, interventional, single-arm, confirmative clinical investigation to evaluate the performance and the safety of PN+HA (NEWEST) for the improvement of skin hydration.
- Trial name
- NCT06821867
- Testing
- PN + HA (Newest)
- Where
- Italy
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mastelli S.r.l
Gastrointestinal Diseases, Stomach Diseases
A Comparison of SmartPill Capsule With Scintigraphy for Determining Gastric Residence Time - Over 65 Years Old
The purpose of this study is to determine the correlation between gastric residence time of the SmartPill Capsule and the time required for partial emptying of a standard radiolabeled meal as measured by gastric emptying…
- Conditions
- Gastrointestinal Diseases, Stomach Diseases, Gastroparesis
- Trial name
- GETOver65 (NCT00682877)
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- The SmartPill Corporation
Atrial Fibrillation (AF), Persistent Atrial Fibrillation
Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)
Conquer-AF is a prospective, multi-center, interventional, non-randomized clinical study that will enroll up to 400 subjects at up to 30 sites across the United States, Europe, and Australia.
- Conditions
- Atrial Fibrillation (AF), Persistent Atrial Fibrillation, Paroxysmal Atrial Fibrillation (PAF)
- Trial name
- Conquer-AF (NCT07298473)
- Testing
- Sphere-9 Catheter Ablation
- Where
- 30 sites in United States, Australia and 4 more
- Volunteers
- 400 people
- Sponsor
- Medtronic Cardiac Ablation Solutions
Venous Ulcer of Leg
Intravascular Ultrasound-Guided Intervention for Venous Leg Ulcers (IGuideU)
This clinical study is a global, prospective, multi-center, randomized controlled trial to determine if the use of intravascular ultrasound (IVUS) as an adjunctive imaging modality and as an interventional treatment guide will…
- Trial name
- IGuideU (NCT04696354)
- Testing
- IVUS, Continued Compression Therapy/Stockings
- Where
- 17 sites in United States, Australia and 3 more
- Volunteers
- 12 people
- Sponsor
- Philips Clinical & Medical Affairs Global
Inflammatory Bowel Diseases, Colitis, Ulcerative
A Study on How Vedolizumab is Given and the Outcomes for Adults With Inflammatory Bowel Disease (VARIETY-Belgium)
IBD consists of either ulcerative colitis or Crohn's disease. The main aim of this study is to describe real-world treatment patterns in adults with moderate to severe ulcerative colitis or Crohn's disease when treated with…
- Conditions
- Inflammatory Bowel Diseases, Colitis, Ulcerative, Crohns Disease
- Trial name
- NCT04959851
- Where
- 10 sites in Belgium
- Volunteers
- 185 people
- Sponsor
- Takeda
Diabetes, Diabetes Mellitus, Type 1
Observational Study to Evaluate the Safety of Levemir® in Diabetes
This study is conducted in Africa, Asia, Europe, Japan and South America. The aim of this observational study is to evaluate the incidence of serious adverse reactions (SARs) while using Levemir® (insulin detemir) under normal…
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- PREDICTIVE™ (NCT00659295)
- Testing
- insulin detemir
- Where
- 13 sites in Belgium, Czechia and 11 more
- Volunteers
- 51,170 people
- Sponsor
- Novo Nordisk A/S
Small Bowel Disease
Ancora-SB Overtube Complete Positioning and Optical Visualization During Endoscopic Procedures
Demonstrate superiority of the Aspero Medical Ancora-SB balloon Overtube compared to the Olympus ST-SB1 Balloon Overtube.
- Trial name
- NCT06111131
- Testing
- Enteroscopy
- Where
- 5 sites in United States
- Volunteers
- 123 people
- Sponsor
- Aspero Medical, Inc.
Chronic Myeloid Leukemia
Nilotinib for Patients With Chronic Myeloid Leukemia in First Line and Any Subsequent Line
This was a non-interventional observational study within the routine chronic myeloid leukemia treatment practice; no further tests were required apart from the assessments routinely performed for Chronic myeloid leukemia patients…
- Trial name
- NOFRETETE (NCT05734053)
- Testing
- Nilotinib
- Where
- 77 sites in Germany
- Volunteers
- 222 people
- Sponsor
- Novartis Pharmaceuticals
Obesity
The ACE Follow-up Study
The Articulating Circular Endoscopic (ACE) Stapler is an investigational system using endoscopic guidance to trans-orally place plications in the stomach in obese subjects to reduce volume and expansion of the fundus and greater…
- Trial name
- NCT01429194
- Testing
- ACE Stapler
- Where
- 6 sites in Argentina, Canada and 2 more
- Volunteers
- 69 people
- Sponsor
- Boston Scientific Corporation
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