Clinical trials: For Intervention
ST-segment Elevation Myocardial Infarction
Distal Protection Device in ST-elevation Myocardial Infarction (STEMI)
The investigators examined the mechanism underlying the lack of benefit from distal protection and thrombus aspiration (DP-TA) in 126 patients with ST-elevation Myocardial Infarction (STEMI) in a prospective, randomized trial.
- Trial name
- NCT01384019
- Testing
- distal protection and thrombus aspiration (The GuardWire Plus (Medtronic Inc.)), c-PCI
- Where
- South Korea
- Volunteers
- 126 people
- Sponsor
- Seoul National University Bundang Hospital
HIV Infections, Alcohol Abuse
Brief Electronic Intervention for Heavy Drinking and Sex Risk Among MSM Seeking HIV Testing
The overall objective of this research is to use both qualitative and quantitative data to inform the development of a technology-based intervention for heavy drinking and sexual risk behavior among men who have sex with men…
- Trial name
- NCT03435783
- Testing
- Brief Electronic Intervention, Attention-Matched Control
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Brown University
Muscle Spasticity
Observational Study of Botox® Treatment for Patients With Upper Limb Adult Spasticity
This is a prospective, non-interventional, observational study to collect data on the use of botulinum toxin Type A in a routine setting in patients with upper limb adult spasticity.
- Trial name
- NCT01387074
- Testing
- botulinum toxin Type A
- Where
- Germany
- Volunteers
- 108 people
- Sponsor
- Allergan
Burnout, Professional, Anxiety
Feasibility of a Yoga- and Mindfulness-Based Intervention for Resident Physicians
The investigators aim to initiate and complete the first investigation of the effect of a yoga-based program on resident physicians' psychological health using a randomized controlled trial to assess feasibility of the program in…
- Conditions
- Burnout, Professional, Anxiety, Depression, Stress
- Trial name
- NCT03687450
- Testing
- RISE yoga-based program
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Psychotic Disorder
Mobile After-Care Support App: Pilot RCT
The overall aim of this program of research is to refine and test the feasibility and acceptability of a newly developed mobile device-delivered app, called Mobile After-Care Support (MACS), to improve patients' coping and…
- Trial name
- MACS-RCT (NCT03955250)
- Testing
- Mobile After-Care Support (MACS) app, Mobile app attention control
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Butler Hospital
Smoking
Tobacco Tactics Website for Veteran Smokers
The purpose of this study is to develop an evidence-based Tobacco Tactics website tailored to veterans based on an intervention tested in the VA.
- Trial name
- NCT00665704
- Testing
- Tobacco Tactics website
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- US Department of Veterans Affairs
Smoking Cessation
Extended Treatment for Smoking Cessation
Adult smokers (21-65) and adolescent smokers (18 - 21) years of age residing in Alameda and Santa Clara counties will serve as the target population for this study.
- Trial name
- NCT01330043
- Testing
- Bupropion, Nicotine patch, Varenicline
- Where
- United States
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- Stanford University
Interventional Vascular Conditions
Clinical Evaluation of the OEC Elite MD for Vascular Procedures at Hamilton General Hospital
The purpose of this study is to collect feedback on imaging guidance adequacy from physicians who use the OEC™ Elite CFD Mobile Fluoroscopy System-Motorized Configuration to perform surgical procedures for which the use of mobile…
- Trial name
- NCT03417713
- Testing
- Fluoroscopic imaging with the OEC Elite Device
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- GE Healthcare
Suicide, Psychosis
Cognitive Behavioral Suicide Prevention for Psychosis: Aim 2
Investigators will evaluate the feasibility and preliminary effectiveness of modified Cognitive Behavioral Suicide Prevention for psychosis (CBSPp) in comparison to services-as-usual (SAU) in a randomized controlled trial.
- Trial name
- NCT05345184
- Testing
- Cognitive Behavioral Suicide Prevention for psychosis (CBSPp), Services as Usual (SAU)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Michigan
Advanced Cancer
Patient-caregiver Communication Intervention for Prognostic Understanding
The purpose of this study is to: (1) develop a communication-based intervention to improve advanced cancer patients' and caregivers' prognostic understanding using communication strategies (e.g., acknowledgment, validation of…
- Trial name
- NCT03833817
- Testing
- Talking about Cancer (TAC)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Weill Medical College of Cornell University
Hazardous Alcohol Consumption
Evaluation of an Internet-based Intervention for Hazardous Drinkers
The purpose of this study is to determine whether the investigators internet-based intervention is effective to help hazardous drinkers reducing their alcohol consumption.
- Trial name
- NCT01075685
- Testing
- interactive online programme to reduce alcohol consumption, Minimum information
- Volunteers
- 1,157 people
- Sponsor
- Institut national de prevention et d'education pour la sante
Stroke, Acute
Solitaire FR Thrombectomy for Acute Revascularisation
The objective of this study was to obtain prospective clinical data on the safety and efficacy of the Solitaire™ FR device for patients diagnosed with acute ischemic stroke.
- Trial name
- STAR (NCT01327989)
- Testing
- Solitaire™ FR device
- Where
- 2 sites in Switzerland
- Volunteers
- 202 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Resilience, Psychological, Advance Care Planning
Facilitating Advance Care Planning Discussions for People With Advanced Cancer
The aims of this study are to (1) identify the advance care planning deliberation process among 20 dyads of patients with advanced cancer and family caregivers and (2) conduct usability testing among 9 dyads to refine the content…
- Trial name
- NCT06061965
- Testing
- Web-based resilience-building intervention
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Illinois Chicago
Cerebral Palsy
Therapeutic Dance Intervention for Children With Cerebral Palsy
Children with cerebral palsy (CP) have motor impairments that may limit participation in standard physical activity (PA) programs. Adapted PA interventions may help address this gap.
- Trial name
- NCT03681171
- Testing
- Therapeutic Dance
- Volunteers
- 9 people
- Sponsor
- Shlomit Aizik
Obesity, Insulin Resistance
Increasing Cure Rate of Hepatitis C Therapy in Obese Hepatitis C Patients
The purpose of this study is to determine whether obese people do not respond to hepatitis C treatment as well as lean people. This research studies whether obese people will show higher sustained virologic response rate if they…
- Conditions
- Obesity, Insulin Resistance, Metabolic Syndrome, Hepatitis C
- Trial name
- NCT00871845
- Testing
- Dietary and Lifestyle modification educational sessions
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Hossam Kandil
HIV, Malnutrition
Shamba Maisha: Pilot Agricultural Intervention for Food Security and HIV Health Outcomes in Kenya
This pilot study aims to determine whether an agricultural intervention will improve food security, prevent treatment failure, reduce co-morbidities, and decrease secondary HIV transmission risk among people living with HIV/AIDS.
- Trial name
- Shamba (NCT01548599)
- Testing
- Multi-sectoral agricultural intervention
- Where
- 2 sites in Kenya
- Volunteers
- 140 people
- Sponsor
- University of California, San Francisco
Pediatric Cancer
An eHealth Psychosocial Intervention for Caregivers of Children With Cancer
The psychosocial needs of children with cancer and their families are well-documented in the literature, including the increased risk of parental posttraumatic stress, parental anxiety, and decreased family functioning.
- Trial name
- NCT05333601
- Testing
- eSCCIP
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Migraine Disorders
An Observational Study of BOTOX® as Headache Prophylaxis for Chronic Migraine
This is an observational study to describe the long term use of Onabotulinumtoxin A (BOTOX®) as prescribed by the physician for headache prophylaxis in adults with chronic migraine. All treatment decisions lie with the physician.
- Trial name
- NCT01686581
- Testing
- botulinum toxin Type A
- Where
- 77 sites in Germany, Italy and 5 more
- Volunteers
- 641 people
- Sponsor
- Allergan
Polyps
Evaluation of an Endoscopic Suturing System for Tissue Apposition in Colonic Polypectomy
The purpose of this study is to show that the surgical site in the bowel wall can be sewn closed in the colon or intestine, with a new sewing device after removal of a benign polyp according to standard of care.
- Trial name
- NCT00553436
- Testing
- Tissue Apposition System (TAS) Device
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Ethicon Endo-Surgery
Stroke, Traumatic Brain Injury
Informal Caregivers ANSWERS-VA
The purpose of this study is to determine the effectiveness of the ANSWERS- VA intervention (Acquiring New Skills While Enhancing Remaining Strengths for Veterans) while also determining it's cost effectiveness in the stroke and…
- Trial name
- NCT02398409
- Testing
- ANSWERS - Acquiring New Skills While Enhancing Remaining Strengths, Control
- Where
- 2 sites in United States
- Volunteers
- 143 people
- Sponsor
- VA Office of Research and Development
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