Clinical trials: For Intervention
CHF, COPD
A Technology Assisted Care Transition Intervention for Veterans With CHF or COPD
Transition from hospital to home places patients in jeopardy of adverse events and increases their risk for rehospitalization. CHF is the most prevalent chronic condition among U.S.
- Trial name
- TACT (NCT02632552)
- Testing
- Technology-assisted care transition intervention, Active attention control
- Where
- 5 sites in United States
- Volunteers
- 140 people
- Sponsor
- VA Office of Research and Development
Anxiety
Brief Anxiety Skills Training Intervention for Veterans in Primary Care
Anxiety symptoms are common among primary care patients, but anxiety is undertreated. Brief behavioral (non-medication) anxiety treatments are needed.
- Trial name
- NCT04829240
- Testing
- Veterans Anxiety Skills Training Intervention, PCMHI Usual Care
- Where
- 2 sites in United States
- Volunteers
- 213 people
- Sponsor
- VA Office of Research and Development
COVID-19
COVID-19 Vaccine Hesitancy Counseling Intervention for Pharmacists
The goal of this clinical trial is to test if virtual facilitation (e.g., video coaching) increases rural pharmacists' ability to implement COVID-19 vaccine hesitancy counseling when compared to a "standard" implementation…
- Trial name
- NCT05926544
- Testing
- Standard implementation webinar and online training, Virtual facilitation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of North Carolina, Chapel Hill
Migraine
Trial of Comprehensive Migraine Intervention
Despite the fact that more than 10% of Americans suffer from migraine, this headache disorder is often not diagnosed and not appropriately treated.
- Trial name
- NCT01071317
- Testing
- Naproxen, Sumatriptan, Migraine education
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Montefiore Medical Center
Nicotine Dependence
Trial on the Effectiveness of Mindfulness Training for Smokers
The Mindfulness Training for Smokers study follows a randomized controlled design with 240 total participants. Both the study group and the control group will be enrolled in the Wisconsin Tobacco Quit Line and will receive four…
- Trial name
- MTS (NCT01093599)
- Testing
- Quit Line plus MTS, Quit Line Only
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- University of Wisconsin, Madison
Vertebral Metastasis
Phase II Trial of Stereotactic Radiation Therapy (SRT) Versus SRT Plus Vertebral Augmentation Procedure (VAP) for Vertebral Metastasis
The purpose of this study is to determine pain control rate (Percentage of patients in each arm that achieve pain control) at the treated site(s) at 1 month, 2-4 months and 5-6 months post-treatment.
- Trial name
- NCT01527292
- Testing
- Stereotactic Radiation Therapy, SRT with Vertebral Augmentation Procedure
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Louisville
Head And Neck Cancer, Oropharynx Cancer
OraTest in Combination With Visual Examination and Visual Examination Alone
Primary Objectives: 1. To assess the ratio in sensitivities of OraTest® in combination with visual examination versus visual examination alone in the detection of serious pathology defined as severe dysplasia, CIS, or cancer of…
- Trial name
- NCT00537199
- Testing
- Visual Examination, OraTest
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Major Depressive Disorder
Goal Achievement After a Change to Vortioxetine in Adults With Major Depressive Disorder
The purpose of this study is to determine the effectiveness of treatment with vortioxetine on participant goal achievement after a change in antidepressant medication for the treatment of major depressive disorder (MDD).
- Trial name
- NCT02972632
- Testing
- Vortioxetine
- Where
- 25 sites in United States
- Volunteers
- 123 people
- Sponsor
- Takeda
Mental Health Issue, Emotional Stress
DISCOVER Workshop Programme for Care Experienced Young People
The NHS DISCOVER team has secured 2-year funding from the Maudsley Charity to tailor the workshop programme the investigators deliver in school Sixth Forms to meet the specific needs of Care Experienced young people.
- Conditions
- Mental Health Issue, Emotional Stress, Emotional Regulation
- Trial name
- NCT05220436
- Testing
- DISCOVER workshop programme
- Where
- 2 sites in United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- South London and Maudsley NHS Foundation Trust
Mental Health
Immigrant Well-being Project: Transdisciplinary Ecological Mental Health Intervention for Mexican Immigrants
The goal of this study is to test a transdisciplinary ecological approach to reducing mental health disparities among Mexican immigrants by adapting and integrating a multilevel community-based advocacy, learning, and social…
- Trial name
- IWP (NCT03926247)
- Testing
- Immigrant Well-Being Project
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Kidney Transplant
Mycophenolate Mofetil and Rapamycin as Secondary Intervention vs. Continuation of Calcineurin Inhibitors in Patients at Risk for Chronic Renal Allograft Failure
A study to determine the effect on renal function in renal transplant patients with biopsy proven Chronic allograft nephropathy (CAN) nephropathy who are switched from a Calcinerin inhibitor (CI) triple drug regimen to a…
- Trial name
- NCT00223678
- Testing
- Rapamycin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Vanderbilt University Medical Center
Tobacco Use Disorder, Smoking Cessation
Development of a mHealth Intervention for Ambivalent Smokers
The current pilot study will assess the feasibility and acceptability of a novel mHealth app designed for people who are ambivalent about quitting smoking.
- Conditions
- Tobacco Use Disorder, Smoking Cessation, Motivation, Behavior, Smoking
- Trial name
- NCT04560868
- Testing
- Control mHealth program, Experimental mHealth program, Nicotine patch
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Bed-ridden Patient, Solid Organ Transplant
Use of an Off-the-Shelf Exergame as an In-Bed Gamified Rehabilitation Intervention for Severely Deconditioned Inpatients: A Feasibility Study
1. Study Title: Use of an Off-the-Shelf Exergame as an In-Bed Gamified Rehabilitation Intervention for Severely Deconditioned Inpatients: A Feasibility Study 2.
- Conditions
- Bed-ridden Patient, Solid Organ Transplant, Post Critical Care
- Trial name
- NCT06937463
- Testing
- Rehabilitation
- Where
- South Korea
- Volunteers
- 26 people
- Sponsor
- Asan Medical Center
Major Depressive Disorder
Brexpiprazole as Adjunctive Therapy in Adults With Major Depressive Disorder
The clinical trial will investigate the effect of brexpiprazole on the concept of life engagement in participants with Major Depressive Disorder (MDD) with a current depressive episode.
- Trial name
- NCT04830215
- Testing
- Brexpiprazole
- Where
- Canada
- Volunteers
- 122 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Overweight and Obesity, Type2 Diabetes
The Mobile Lifestyle Intervention for Food and Exercise Study
The goal of the study is to examine long term sustained weight loss digital intervention in a diverse cohort of adults with overweight/obesity.
- Trial name
- mLIFE (NCT05176847)
- Testing
- Podcasts and tips of the day (within app), mLIFE app (self-regulation features), mLIFE app (social support features)
- Where
- United States
- Volunteers
- 243 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Alcohol Use Disorder, Eligible to go Into the MRI Scanner
Clinical Intervention in Alcohol Use Disorder
Long-term abstinence from alcohol is supported by a compensatory mechanism in functional brain connectivity, a potential brain biomarker that could be an intervention target.
- Conditions
- Alcohol Use Disorder, Eligible to go Into the MRI Scanner, Short-term Abstinence From Alcohol Use (2 Week Abstinent)
- Trial name
- NCT02168400
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of Minnesota
COVID-19, Cardiorespiratory Failure
Lift Mobile Mindfulness for COVID-19 Distress Symptoms
This is a randomized clinical trial (RCT) nested within the NIH PETAL Network's COVID cohort study (BLUE CORAL [Biology and Longitudinal Epidemiology: COVID Observational Study]) of patients hospitalized for COVID-19-related…
- Trial name
- LIFTCOVID (NCT04581200)
- Testing
- Lift
- Where
- 4 sites in United States
- Volunteers
- 56 people
- Sponsor
- Duke University
Cerebral Palsy, Hypoxic-Ischemic Encephalopathy
Therapeutic Intervention Supporting Development From NICU to 6 Months for Infants Post Hypoxic-Ischemic Encephalopathy
The purpose of this study is to evaluate the feasibility and begin to evaluate the effect of a sensorimotor intervention (SMI) provided in the first 6 months of life for infants with hypoxic-ischemic encephalopathy.
- Trial name
- NCT05130528
- Testing
- Sensorimotor Intervention
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- University of Southern California
Intimate Partner Violence, Self-efficacy
Recovering From Intimate Partner Violence Through Strengths and Empowerment (RISE)
Intimate partner violence (IPV) is a major health concern for women Veterans. IPV is associated with numerous physical and mental health conditions.
- Trial name
- RISE (NCT03261700)
- Testing
- RISE, Information and referral condition
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- VA Office of Research and Development
Nicotine Dependence, Cigarettes
Penn State TXT2STAYQUIT Study- a Texting Study to Help Hospitalized Smokers Stay Quit
This study aims to pilot a method of collecting the post-discharge follow-up data required by the Joint Commission Tobacco Measure Set, using text messages sent to and received from patients' cellular-telephones.
- Trial name
- NCT02986711
- Testing
- Motivational Text Messages, Control
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
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