Clinical trials: For Intervention
Myocardial Infarction
Relationship Between Primary Percutaneous Coronary Intervention, Door-to-balloon Times, and Mortality for Heart Attack Patients Across England
The degree to which elevated mortality associated with weekend or night-time hospital admissions reflects poorer quality of care ('off-hours effect') is a contentious issue.
- Trial name
- NCT02374190
- Testing
- Standard Hospital Care
- Where
- United Kingdom
- Volunteers
- 42,677 people
- Sponsor
- London School of Economics and Political Science
Adherence, Medication, HIV/AIDS
Short Adherence Intervention for Viral Re-suppression
In the era of test-and-treat, with anticipated high numbers of patients who will have unsuppressed viral load (VL) due to poor adherence, simple, short and standardized adherence interventions with documented efficacy will be…
- Trial name
- SAVIR (NCT03242980)
- Testing
- Structured adherence counseling
- Where
- 12 sites in Lesotho
- Volunteers
- 928 people
- Sponsor
- Swiss Tropical & Public Health Institute
Healthy Aging, Risk Reduction
Validation of the REMINDER Dementia Risk Reduction Program
Until now, neuropsychological interventions aimed to optimize cognitive function and to have functional impact in individuals at risk of AD (MCI patients) were scarce in validity studies.
- Conditions
- Healthy Aging, Risk Reduction, Old Age; Dementia
- Trial name
- REMINDER (NCT05296980)
- Testing
- REMINDER, Brain health Psychoeducation
- Where
- Portugal
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Esophageal Cancer, Gastric Cancer
VITAMin Insufficiency in Esophagogastric Neoplasms
Rationale: Esophageal cancer and gastric cancer are among the top ten most common cancers worldwide. Both diseases have major impact on the nutritional status of patients and their quality of life.
- Conditions
- Esophageal Cancer, Gastric Cancer, Vitamin Disease, Quality of Life
- Trial name
- VITAMIN (NCT05281380)
- Testing
- GIKAVI
- Where
- Netherlands
- Volunteers
- 107 people
- Sponsor
- Zuyderland Medisch Centrum
Deep Brain Stimulation
Ketamine in Deep Brain Stimulation (DBS) Surgery
Deep brain stimulation (DBS) is a well-established and effective treatment for motor symptoms resulting from idiopathic Parkinson's disease (PD).
- Trial name
- NCT04716296
- Testing
- Ketamine, Saline
- Where
- Israel
- Volunteers
- 35 people
- Sponsor
- Rabin Medical Center
Depression
Interventions for Depressed Low Income Mothers and Their Infants
This study will compare three interventions for depressed, low income mothers and determine which is most effective in treating maternal depression and in fostering development in infants.
- Trial name
- NCT00105573
- Testing
- Maternal interpersonal psychotherapy (IP), Infant-parent psychotherapy, Informational meetings plus treatment as usual
- Where
- United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Surgical Procedure, Unspecified
Posterior Wall Osteotomy for Old Acetabular Fracture
Posterior wall osteotomy would be conducted to manage the old acetabular fracture. The outcome was reviewed to assess the feasibility of the surgical procedure.
- Trial name
- osteotomy (NCT03193840)
- Testing
- posterior wall osteotomy
- Where
- 2 sites in China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hebei Medical University Third Hospital
Anxiety
Music for Anxiety in Critically Ill Patients
Rationale: Anxiety is common in critically ill patients, and has likely become more prevalent in the recent decade due to the imperative of the recent PADIS guidelines to use low levels of sedation and strive for wakefulness.
- Trial name
- RELACS (NCT04796389)
- Testing
- Music
- Where
- 3 sites in Netherlands
- Volunteers
- 104 people
- Sponsor
- Erasmus Medical Center
Suicide, Risk Reduction
Building Stronger Allies
BSA is a novel, computerized intervention specifically designed for active military personnel with the intent to reduce two risk factors known to be associated with suicide outcomes.
- Trial name
- BSA (NCT03571750)
- Testing
- Building Stronger Allies, Health Education Training
- Where
- United States
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- Florida State University
Physician Burnout
Evaluating an Intervention for Physician Burnout
The goals of this randomized controlled trial are 1) to test the efficacy of an app-based program in reducing physician burnout vs.
- Trial name
- NCT06969950
- Testing
- App-Delivered Mindfulness Training (MT)., Online Virtual Training
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brown University
Increase Repeat Blood Donation Attempts Among First-time Donors
Community-based Communication for Blood Donation in Ghana
A randomized controlled trial to evaluate the effectiveness of the WhatsApp groups or docudrama compared to a control group (usual engagement with blood services) on repeat blood donation attempts among first-time blood donors in…
- Trial name
- C-CAD (NCT05973890)
- Testing
- WhatsApp, docudrama
- Where
- United States
- Volunteers
- 882 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Empathy, Burnout, Professional
Educational Intervention for the Development of Professionals Skills in Family Medicine and Community Nursing Residents
BACKGROUND The burnout syndrome among health care workers frequently rises to prevalence above 50%. One of the consequences most supported by the literature is the impoverishment of the therapeutic alliance, triggered by a loss…
- Trial name
- PROEMPATHY (NCT04625582)
- Testing
- Face-to-face, Online
- Where
- Spain
- Volunteers
- 340 people
- Sponsor
- Galician South Health Research Institute
Leber's Hereditary Optic Neuropathy (LHON)
Post Authorisation Safety Study With Raxone in LHON Patients
This study is a multicentre, prospective, non-interventional post-authorisation safety study (PASS) of the clinical outcomes for patients with LHON treated with Raxone®. No medication will be provided as part of this study.
- Trial name
- PAROS (NCT02771379)
- Testing
- Idebenone
- Where
- 26 sites in Austria, France and 4 more
- Volunteers
- 229 people
- Sponsor
- Santhera Pharmaceuticals
Obesity, Childhood
Together We STRIDE (Strategizing Together Relevant Interventions for Diet and Exercise)
Obesity among Hispanic children in the Lower Yakima Valley of Washington State is alarmingly high. This study proposes to implement a comprehensive, multi-level intervention among children, families, the schools, and the…
- Trial name
- NCT02982759
- Testing
- Multi-Level Intervention, Genetic Newsletters
- Where
- United States
- Volunteers
- 888 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Coronary Artery Disease
Intra-Individual Comparison of Sirolimus and Paclitaxel Coated Stent (FRE-RACE Study)
The main objective of this study is to assess the safety and effectiveness of the Sirolimus eluting Cypher Select(TM) stent in reducing angiographic in-stent late loss in de novo native coronary lesions as compared to the…
- Trial name
- NCT00130546
- Testing
- Paclitaxel-eluting TAXUS(TM), Sirolimus eluting Cypher Select(TM)
- Where
- Germany
- Volunteers
- 112 people
- Sponsor
- University Hospital Freiburg
Psychological Disease
RinasciMENTE, An Internet-Based Self-Help Intervention for People With Psychological Distress Due to COVID-19
This study aims is the evaluation of the efficacy and feasibility of RinasciMENTE, the Randomized Controlled Clinical Trial compared with a waiting list control group.
- Trial name
- NCT04907903
- Testing
- internet-based intervention
- Volunteers
- 128 people
- Sponsor
- Catholic University of the Sacred Heart
Mood, Stress, Psychological
Stress Management for Cancer Patients: How Well Does it Work? (C2H-D)
Psychological interventions for cancer patients have been tested and found to reduce stress and improve quality of life. These interventions have been tested at academic medical centers but have not been available for use by…
- Trial name
- C2H-D (NCT02070250)
- Testing
- From Cancer to Health (C2H-D)
- Where
- 15 sites in United States
- Volunteers
- 158 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Physical Activity, Cancer Survivor
Move 2 Health: A Couple-Based Physical Activity Intervention for Cancer Survivors
This pilot study will develop and test a couple-based physical activity intervention among cancer survivors and their partners. Aim 1: To determine the feasibility and acceptability of a couple-based physical activity…
- Trial name
- NCT03266718
- Testing
- Physical Activity Intervention
- Volunteers
- 40 people
- Sponsor
- Duke University
Meningitis in Children
The Use of an Audio-visual Method in Counseling for Pediatric Lumbar Puncture Procedure
The goal of this clinical trial is to compare the use of usual verbal counseling supported by a video illustration comparing to the use of usual verbal counseling alone prior to obtaining spinal fluid ( Lumbar puncture - LP )…
- Trial name
- NCT07409220
- Testing
- Audio-visual tool/ Video
- Where
- Oman
- Volunteers
- 154 people
- Sponsor
- Oman Ministry of Health
Gastric Cancer Patient
Safety, Feasibility and Effect of an Individualized Physical Activity Intervention for Gastric Cancer Patient Undergoing Minimally Invasive Gastrectomy: a Pilot Study
Gastric cancer is a major health issue and one of the most common malignance in Korea. With the popularization of cancer screenings and increasing the average lifespan, the number of gastric cancer patients is increased.
- Trial name
- NCT01751880
- Testing
- physical activity intervention
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Yonsei University
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