Clinical trials: For Intervention
Knee Osteoarthritis, Osteoarthritis
"Bimodal vs Unimodal High-Intensity Pulsed Electromagnetic Field Therapy in Older Adults With Knee Osteoarthritis"
This randomized, double-blind clinical trial aims to evaluate the effect of high-intensity pulsed electromagnetic field therapy (HI-PEMF) applied either exclusively on the knee joint or bimodally on the knee and quadriceps, in…
- Conditions
- Knee Osteoarthritis, Osteoarthritis, Osteo Arthritis of the Knee, Gonarthrosis
- Trial name
- HIPEMF-OAK (NCT07198750)
- Testing
- HI-PEMF - Knee (Chronic Pain Protocol), HI-PEMF - Quadriceps (Muscle Strengthening Protocol), Home-Based Exercise Program
- Where
- Mexico
- Volunteers
- 64 people
- Sponsor
- Hospital Civil de Guadalajara
HPV-Related Carcinoma
Integrating Primary & Secondary Interventions for Cervical Cancer Prevention in Primary Care Settings
The purpose of this study is to determine whether a mobile health educational intervention for Human PapillomaVirus (HPV) Vaccination promotion and cervical cancer screening in Primary Care settings is a feasible behavioral…
- Trial name
- NCT03033550
- Testing
- brief negotiated mobile application
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Psychopathology
Can Applying the Science of Habit Formation to Contemplative Practice Improve Outcomes
In the present study, the investigators will conduct a confirmatory efficacy trial to test whether improving practice automaticity (i.e., habit formation) of self-compassionate touch improves outcomes in the predicted direction.
- Trial name
- NCT05866718
- Testing
- Self-Compassionate Touch Intervention, Habit Formation Tools
- Where
- United States
- Volunteers
- 497 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Long-term Effects of Cancer Treatment, Long-term Effects Secondary to Cancer Therapy in Adults
Web-based Intervention for Long-term Breast Cancer Survivors
The number of breast cancer survivors is growing. More cured women are becoming long-term survivors of breast cancer (LS-BC) at least 5 years after diagnosis and after treatment has been completed.
- Trial name
- CUMACA-M (NCT05322460)
- Testing
- CUMACA-M Program
- Where
- Spain
- Volunteers
- 182 people
- Sponsor
- Cristina García-Vivar
Congenital Heart Disease
Outcome of Patients With Congenital Heart Disease
Advanced surgical and medical healthcare systems have resulted in an increased prevalence of children and adults with congenital heart disease in Western countries. These patients often necessitate non-cardiac interventions.
- Trial name
- OUTCARDIOP (NCT03913520)
- Testing
- Outcome research
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Thoracic Surgical Procedures
Sodium Oxybate for Postoperative Sleep Disturbance After Thoracic Surgery
This is a single-center, randomized, double-blind, placebo-controlled trial. Three hundred-sixty adult patients undergoing elective thoracoscopic surgery will be randomly allocated at a 1:1 ratio to receive either intraoperative…
- Trial name
- NCT07794982
- Testing
- sodium oxybate
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Jingsheng Lou
Stress Urinary Incontinence
Concurrent Surgery for Prolapse and Stress Urinary Incontinence to Reduce Further Surgery for Incontinence
Urinary incontinence is a common and distressing medical condition which affects 26% of women in developing countries.Globally upto 54% women suffer from pelvic organ prolapse and stress urinary incontinence concomitantly.Women…
- Trial name
- NCT06521450
- Testing
- anti incontinence surgery
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Shalamar Institute of Health Sciences
Underage Drinking
Efficacy of a Web-Based Alcohol Intervention for High School Students
This study evaluates the efficacy of the eCHECKUP TO GO as an intervention to reduce underage drinking and the associated negative consequences among high school seniors.
- Trial name
- NCT03613818
- Testing
- eCHECKUP TO GO
- Where
- United States
- Volunteers
- 311 people, healthy volunteers welcome
- Sponsor
- Boise State University
Endometrial Cancer
Metabolic Effect of Exercise and Diet in Endometrial Cancer Patients Eligible for Staging Surgery.
Background: Endometrial cancer is one of the diseases linked to obesity in women. In Mexico, about 7.6 women out of every 100,000 are diagnosed with this type of cancer, and nearly three-quarters of these women have obesity.
- Trial name
- NCT07025213
- Testing
- Diet and exercise., Diet.
- Where
- Mexico
- Volunteers
- 80 people
- Sponsor
- National Institute of Cancerología
Myocardial Reperfusion Injury
Role of Endothelin in Microvascular Dysfunction Following PCI for NSTEMI
Percutaneous coronary intervention (PCI) for acute coronary syndromes frequently fails to restore myocardial perfusion despite establishing epicardial vessel patency.
- Trial name
- BQ-123 (NCT00586820)
- Testing
- BQ-123
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Mayo Clinic
Attention Deficit Hyperactivity Disorder (ADHD)
Internet-Based Behavioural Parent Training Intervention for Children With Attention Deficit/Hyperactivity Disorder
This study aims to investigate the effectiveness of an Internet-based behavioural parent training intervention on children's ADHD symptoms and children's and parents' mental health status.
- Trial name
- NCT06170996
- Testing
- Internet-based behavioral parent training (I-BPT)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Wuhan Mental Health Centre
Moderate Depression, Clinical Depression
Task Sharing Counseling Intervention by Community Health Workers for Prenatal Depression in South Africa
The objective of this randomised controlled trial (RCT) is to determine the effectiveness and cost-effectiveness of a task sharing counseling intervention for maternal depression in South Africa(i.e.
- Conditions
- Moderate Depression, Clinical Depression, Postpartum Depression
- Trial name
- AFFIRM-SA (NCT01977326)
- Testing
- basic counselling by lay-health workers, Enhanced usual care
- Where
- 2 sites in South Africa
- Volunteers
- 4,205 people
- Sponsor
- University of Cape Town
Clostridium Difficile Infection Recurrence
ACX-362E [Ibezapolstat] for Oral Treatment of Recurrent Clostridioides Difficile Infection
Single-arm trial to evaluate the safety and efficacy of ACX-362E [ibezapolstat] in patients with recurrent C. difficile infection (CDI).
- Trial name
- NCT07513285
- Testing
- Ibezapolstat
- Where
- 19 sites in United States
- Volunteers
- 20 people
- Sponsor
- Acurx Pharmaceuticals Inc.
Carpal Tunnel Syndrome, Trigger Finger
Tourniquet vs. No Tourniquet for Carpal Tunnel and Trigger Finger Release
Background: Trigger finger and carpal tunnel syndrome are two of the most common conditions treated by the hand surgeon. During these procedures, a tourniquet is often used to minimize bleeding and improve visualization of the…
- Trial name
- NCT04354415
- Testing
- Carpal tunnel or trigger finger release
- Where
- Canada
- Volunteers
- 67 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Domestic Violence
Testing the Effectiveness of a Safety-promoting Intervention in Antenatal Care
Domestic violence during pregnancy can directly or indirectly cause maternal and fetal morbidity and even mortality. The investigators have validated the Abuse Assessment Screen to the Nepali context for use with a color-coded…
- Trial name
- NCT05199935
- Testing
- Video, Control
- Where
- 2 sites in Nepal
- Volunteers
- 2,230 people
- Sponsor
- Norwegian University of Science and Technology
Dementia
The Black Immigrant Project
This stage I trial will examine if the culturally adapted ACES intervention affects cognitive appraisal (self-efficacy and dysfunctional thoughts) and behavioral activation with Black immigrant living with dementia and their care…
- Trial name
- NCT07546708
- Testing
- Active Caregiving: Enhancing Skills
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Minnesota
Preterm Infant, Full-term Infant
A Novel Parent Education Program for Early Intervention
One in ten infants born in the USA is born preterm before 37 weeks of gestation and 50% of those will have motor and cognitive delays requiring intervention at school age.
- Trial name
- NCT04266717
- Testing
- Baby Play Intervention, Milestone Education
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Sedentary Lifestyle
Virtual Advisors for Physical Activity Promotion in Underserved Communities
The primary aim of this research study is to evaluate the effectiveness of a computer-based 'virtual lay advisor' intervention relative to a proven human lay advisor/promotore intervention to promote regular walking among…
- Trial name
- COMPASS2 (NCT02111213)
- Testing
- Virtual Advisor, Promotora for physical activity
- Where
- United States
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- Stanford University
Crohn Disease (CD)
Hybrid Endoscopic Stricturotomy Plus Balloon Dilation Versus Stricturotomy Alone for Short Crohn's Disease Strictures
Crohn's disease is a chronic condition that can lead to inflammation and narrowing (strictures) of the intestine, causing symptoms like pain, bloating, and difficulty with bowel movements.
- Trial name
- HEIST (NCT06958159)
- Testing
- Endoscopic Stricturotomy, Endoscopic Balloon Dilation
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Asian Institute of Gastroenterology, India
Axial Spondyloarthritis
The Effect of Exercise on Disease Activity and Cardiovascular Risk for Patients With Axial SpondyloArthritis
The overall aim of this multicenter randomised controlled trial (RCT) is to investigate if exercise can modify the disease course and prevent comorbidity in patient with spondyloarthritis (SpA).
- Trial name
- ESpA (NCT02356874)
- Testing
- Exercise
- Where
- 4 sites in Norway, Sweden
- Volunteers
- 100 people
- Sponsor
- Diakonhjemmet Hospital
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