Clinical trials: For Intervention
Hypoxia, Endoscopy
Nasal Continuous Positive Airway Pressure Versus Standard Care During Procedural Sedation for Gastrointestinal Endoscopy
This study is a randomized controlled trial comparing oxygen delivery by nasal mask with continuous positive airway pressure versus standard care (nasal cannula or standard facemask) during propofol-based sedation for…
- Conditions
- Hypoxia, Endoscopy, Anesthesia Morbidity
- Trial name
- NCT03369197
- Testing
- Nasal Mask, Control: Nasal Cannula
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Behavior, Health
Supportive and Dignified Maternity Care in Public Health Facilities
Brief Summary Poor psychosocial support and demeaning care during childbirth in health facilities are common worldwide, particularly in low- and middle-income countries.
- Trial name
- SDMC (NCT06808360)
- Testing
- Supportive and Dignified Maternity Care
- Where
- Pakistan
- Volunteers
- 314 people
- Sponsor
- Aga Khan University
Psychiatric Disorder
Cognitive Model for Behavioral Interventions as a Personalized Intervention for Patients With Serious Mental Illness
The aim of this clinical study is to investigate whether CoMBI-SMI helps to reduce behavioral problems and psychiatric complaints in Serious Mental Illness (SMI) populations complaints and to reduce the burden on informal…
- Trial name
- NCT05820360
- Testing
- CoMBI-SMI
- Where
- Netherlands
- Volunteers
- 94 people
- Sponsor
- Vrije Universiteit Brussel
Knee Osteoarthritis
Internet Intervention to Improve Physical Activity in Early Knee Osteoarthritis
OPEN (Osteoarthritis Physical Activity and Exercise Net) is a website created based on a well developed behavioural theory. This intervention is developed for people with early knee osteoarthritis (OA) who have been sedentary.
- Trial name
- OPEN (NCT01608282)
- Testing
- OPEN website
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- University of British Columbia
Gestational Diabetes Mellitus (GDM)
Implementation and Evaluation of Bump2Baby and Me+ Programme for Gestational Diabetes Mellitus in Routine Maternity Care Setting.
Gestational diabetes mellitus (GDM) affects approximately 1 in 7 pregnancies globally and is associated with significant short and long-term health consequences for both mothers and infants.
- Trial name
- B2B&ME+ (NCT07189221)
- Testing
- Life Style Intervention
- Volunteers
- 3,600 people
- Sponsor
- University College Dublin
Low Female Sexual Arousal, Low Female Sexual Desire
Group Psychoeducational Treatment for Women With Sexual Arousal Difficulties, Phase II
The purpose of this study is to pilot test and determine the efficacy of a psychoeducational intervention (PED) we recently piloted in a group format for women with acquired sexual arousal disorder (FSAD). HYPOTHESES: 1.
- Trial name
- Group PED (NCT01706406)
- Testing
- Brief psychoeducational intervention for female sexual arousal disorder
- Where
- 2 sites in Canada
- Volunteers
- 98 people
- Sponsor
- University of British Columbia
Alcohol Drinking, Wounds and Injuries
Brief Intervention for Alcohol Use Among Injured Patients
The underlying hypothesis that providing brief interventions to individuals who engage in potentially harmful patterns of alcohol use will alter their drinking behavior and therefore avoid negative consequences.
- Trial name
- NCT00278785
- Testing
- Brief Motivational Interview
- Where
- United States
- Volunteers
- 830 people
- Sponsor
- University of California, Davis
Stress Urinary Incontinence (SUI)
The Effect of Different Delivery Positions on Pelvic Floor Function.
This study is a prospective, multicenter, randomized controlled trial. Baseline data will be collected from eligible subjects recruited during the third trimester of pregnancy.
- Trial name
- NCT07081321
- Testing
- Lithotomy position, Lateral Position, Upright Position
- Where
- China
- Volunteers
- 1,992 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Neonatal Abstinence Syndrome
Utility of Psychosocial Intervention in Improving Outcome for Methadone-exposed Infants and Their Mothers
Opiate drug abuse/addiction is a significant co-morbidity in pregnancy. Opiate maintenance program enhances the outcome of pregnancies for the mother and the infant.
- Trial name
- HOPE (NCT01889121)
- Testing
- Structured psychosocial intervention
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Dr. Henry Akinbi
Carpal Tunnel Syndrome
Combined Manual Therapy and Percutaneous Neuromodulation for Moderate Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy and can cause pain, numbness, tingling, and functional impairment of the hand.
- Trial name
- MANUCTS (NCT07654621)
- Testing
- Combined Manual Therapy and Ultrasound-Guided Percutaneous Neuromodulation, Postsurgical Rehabilitation
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Universidad Europea de Valencia
Palliative Care, Advanced Cancer
A Feasibility Study of Death Education Intervention for Family Caregivers of Advanced Cancer Patients
Advanced cancer is the leading cause of death in the world and China. Family caregivers, as the closest individuals to advanced cancer patients, suffer from a range of psychological and spiritual issues due to patients' impending…
- Conditions
- Palliative Care, Advanced Cancer, Family Caregivers
- Trial name
- NCT07367984
- Testing
- Death education intervention for family caregivers of advanced cancer patients
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The Hong Kong Polytechnic University
Suicide
Suicide Prevention for Sexual and Gender Minority Youth (Case Series)
The overarching goal of this study is to develop a suicide prevention program for sexual-and-gender-minority youth and emerging adults.
- Trial name
- NCT04757649
- Testing
- Safety Planning Intervention with Navigation Services
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Coronary Angiography and Intervention
The Primary Endpoint is to Compare the Incidence of Forearm RAO Between Distal and Traditional Radial Access Assessed by Vascular Ultrasound At Discharge
The primary endpoint is to compare the incidence of forearm RAO between distal and traditional radial access for coronary angiography and intervention
- Trial name
- RAO (NCT06688747)
- Volunteers
- 230 people
- Sponsor
- Assiut University
Psychosocial Deprivation, Work-Related Stress
Family Supportive Supervisor Training and Workplace Assessment Tool
This study will evaluate the effectiveness of FSST 2.0 (family supportive supervisor training plus support for use of family and sick leaves) using a randomized control trial design.
- Conditions
- Psychosocial Deprivation, Work-Related Stress, Life-work Imbalance
- Trial name
- FSST (NCT05080426)
- Testing
- Family Supportive Supervisor Training 2.0
- Where
- United States
- Volunteers
- 1,175 people, healthy volunteers welcome
- Sponsor
- Work Life Help
Bariatric Surgery Candidate
OAGB-MGB Conversions for Post-operative Complications
Laparoscopic mini/one anastomosis gastric bypass (MGB/OAGB) is a relatively new bariatric procedure and is gaining ground over the surgical approach for morbid obesity as a safe and effective operation.
- Trial name
- NCT04641715
- Testing
- OAGB-MGB
- Where
- Italy
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Federico II University
Body Image
The Impact of a Podcast-based Body Image Intervention Among Millennial Women
The goal of this three-arm randomized controlled trial is to evaluate the acceptability and efficacy of two podcast-based interventions -- a podcast with an accompanying journal and the same podcast without a journal -- which aim…
- Trial name
- NCT07113678
- Testing
- Body confidence podcast episode and supplementary exercises in a journal, Body confidence podcast episode, Non-body image-related podcast episode
- Where
- United States
- Volunteers
- 1,351 people, healthy volunteers welcome
- Sponsor
- University of the West of England
Hereditary Periodic Fever Syndromes, Cryopyrin-associated Periodic Syndromes (CAPS)
Ilaris NIS in Korea
This is a study to evaluate safety and effectiveness of Ilaris in adult and pediatric patients receiving the drug in a clinical setting for any of the following indications, Hereditary Periodic Fever Syndromes…
- Conditions
- Hereditary Periodic Fever Syndromes, Cryopyrin-associated Periodic Syndromes (CAPS), Colchicine Resistance Familial Mediterranean Fever (crFMF), TNF Receptor Associated Periodic Syndrome (TRAPS)
- Trial name
- REASSURE (NCT06838143)
- Testing
- Ilaris
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Novartis Pharmaceuticals
Health Behavior
Healthy Parent Carers Feasibility Study
This study is a feasibility study of a peer-led group-based health promotion intervention for parent carers. It will used a parallel group randomised controlled trial design to compare a group based intervention called Healthy…
- Trial name
- NCT03705221
- Testing
- Healthy Parent Carers group programme, Healthy Parent Carers online resources
- Where
- 6 sites in United Kingdom
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Quality of Care
Evaluation of a Nurse Mentorship and Digital Health Package Intervention in Kenya
The investigators will conduct a cluster randomized controlled trial in maternity facilities in Kenya to evaluate the impact of a maternal and neonatal health package intervention on patient and provider outcomes.
- Trial name
- NCT05110521
- Testing
- PROMPTS, MENTORS
- Where
- Kenya
- Volunteers
- 10,992 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Acute Myocardial Infarction (AMI)
Dexrazoxane to Protect Against Hemorrhagic STEMI
This Phase Ila trial evaluates whether the intravenous administration of Dexrazoxane can reduce permanent heart muscle damage in patients undergoing standard stent procedures (PCI) for a severe heart attack (STEMI).
- Trial name
- SHIELD-MI (NCT07502521)
- Testing
- Dexrazoxane, Normal Saline
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Rohan Dharmakumar
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