Clinical trials: For Intervention, open to volunteers
Respiratory Failure, Anxiety
Improving Psychological Outcomes for Acute Respiratory Failure Survivors Using a Self-Management Intervention
A growing number of patients are surviving a stay in the intensive care unit (ICU) but may experience long-lasting psychological problems, but research evaluating such treatment for ICU patients is scant.
- Conditions
- Respiratory Failure, Anxiety, Critical Illness
- Trial name
- SMARA (NCT06341972)
- Testing
- Cognitive behavioral therapy based self-management for anxiety
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Lung Cancer, Smoking Behaviors
Health Opportunities and Promoters of Equitable Screening for Lung Cancer
The goal of this clinical trial is to promote lung cancer screening (LCS) uptake among Hispanic current and former smokers. The main questions it aims to answer are: What barriers do current and former Hispanic smokers face in…
- Conditions
- Lung Cancer, Smoking Behaviors, Diagnosis
- Trial name
- HOPES (NCT05784922)
- Testing
- Educational Lung Cancer Screening (LCS) Video
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Massachusetts General Hospital
Functional Abdominal Pain Syndrome
Digital Psychological Intervention for Pediatric Functional Abdominal Pain Disorders in Primary Care
The project involves researching two psychological treatments for functional abdominal pain in children. The treatments will be offered to children as an early intervention, at primary care level.
- Trial name
- FAPD (NCT06481072)
- Testing
- Digital patient education, Digital patient education and iCBT
- Where
- Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Safety
Evaluating a Shared Decision-making Intervention for Families About Firearm Storage
Investigators will conduct a randomized controlled trial assessing effectiveness of the Family Safety Check-In website on firearm storage practices.
- Trial name
- NCT07522112
- Testing
- Family Safety Check-In, AAP Resource
- Where
- United States
- Volunteers
- 548 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Eating Disorders
Eating Disorder Chatbot Optimization
The purpose of this study is to optimize an automated digital chatbot intervention for adults with clinical or subclinical eating disorders.
- Trial name
- NCT07218302
- Testing
- Digital Chatbot Program
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- Washington University School of Medicine
No Reflow Phenomenon, Reperfusion Injuries, Myocardial
Evaluating SGLT2 Inhibitors for the Reduction of No-Reflow Phenomenon in Patients Undergoing PCI
Study Background \& Purpose: The no-reflow phenomenon is a significant complication occurring in patients with acute myocardial infarction who undergo percutaneous coronary intervention (PCI).
- Conditions
- No Reflow Phenomenon, Reperfusion Injuries, Myocardial, Myocardial Infarction, STEMI - ST Elevation Myocardial Infarction
- Trial name
- NCT07898709
- Testing
- Empagliflozin (SGLT2i), dapagliflozin, Standard medical treatment
- Where
- 4 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University
Bipolar Disorder, Bipolar and Related Disorders
Targeted Alternating Current and Cognitive Training Intervention for Cognitive Control in Bipolar Disorders
This study is testing whether a type of gentle brain stimulation, combined with computer-based brain training exercises, can help improve thinking skills in Veterans with bipolar disorder.
- Conditions
- Bipolar Disorder, Bipolar and Related Disorders, Veterans, Suicide
- Trial name
- TACTIC-BD (NCT07845409)
- Testing
- Soterix 1x1 tES mini-CT
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Chronic Kidney Disease 5D, Secondary Hyperparathyroidism
A Observational Study to Evaluate the Efficacy and Safety of Pacitol Inj.
The purpose of this study is to evaluate the efficacy and safety of pacitol Inj.(paricalcitol) for secondary hyperparathyroidism with stage 5D chronic kidney disease (CKD 5D) receiving hemodialysis
- Trial name
- NCT06126016
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Diabetic Foot Disease
Development and Pilot Application of a Solution-Focused Intervention for Social Isolation in Elderly Diabetic Foot Patients
The goal of this interventional study is to develop and preliminarily evaluate a solution-focused model-based intervention program for reducing social isolation in elderly patients with diabetic foot ulcers.
- Trial name
- NCT07787884
- Testing
- Intervention Group
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Anhui Medical University
Borderline Personality Disorder
Testing Interventions for Borderline Personality Disorder.
Borderline personality disorder (BPD) is a life-threatening, costly public health crisis affecting ~1-3% of North Americans, with 10% dying by suicide and annual healthcare costs of ~$63k (Canadian Dollars)/patient.
- Trial name
- NCT06458933
- Testing
- Sage, Supportive Individual Psychotherapy
- Where
- Canada
- Volunteers
- 304 people
- Sponsor
- York University
Food Insecurity, Carotenoid Status
Produce Prescriptions and Veggie Meter Scores for College Food Security
The goal of this pilot intervention study is to learn if providing weekly produce boxes helps college students who struggle to afford healthy food. It will also test if this program is practical to run on a college campus.
- Conditions
- Food Insecurity, Carotenoid Status, Produce Prescription
- Trial name
- NCT07511699
- Testing
- Produce boxes
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Atrial Fibrillation (AF), Cardiomyopathy, Secondary
Patient Selection and Long-Term Outcomes of Pace & Ablate Strategy in Atrial Fibrillation
Atrioventricular node ablation with permanent pacing (the "pace-and-ablate" strategy) controls ventricular rate in atrial fibrillation that has not responded to drug therapy or catheter ablation.
- Conditions
- Atrial Fibrillation (AF), Cardiomyopathy, Secondary, Pacing-Induced Cardiomyopathy, Heart Failure
- Trial name
- REPACE (NCT07852221)
- Where
- 5 sites in Poland, Switzerland and 1 more
- Volunteers
- 2,600 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Nasopharyngeal Cancinoma (NPC)
Multimodal Evaluation-Guided Surveillance-Intervention With Endoscopic Selective Neck Dissection for Post-Radiotherapy N3 Nasopharyngeal Carcinoma
This randomized trial evaluates a multimodal surveillance strategy in nasopharyngeal carcinoma patients with high-risk N3 cervical lymph node involvement after radiotherapy.
- Trial name
- NCT07692906
- Testing
- Multimodal Evaluation-Guided Surveillance Strategy
- Volunteers
- 80 people
- Sponsor
- Xuelei Ma MD
Pregnancy, Dietary Inflammatory Index (DII)
Pregnancy Anti-inflammatory Diet Intervention Study
Dietary patterns may influence maternal inflammatory status and pregnancy outcomes. However, structured anti-inflammatory dietary interventions specifically designed for pregnant women remain limited.
- Trial name
- PAID2026 (NCT07890441)
- Testing
- Anti-inflammatory Dietary Intervention
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Smoking Cessation, Early-Stage Cancer
Multi-Theory Model-Based AI Agent Intervention for Smoking Cessation in Early-Stage Cancer Patients
The goal of this clinical trial is to evaluate the effectiveness of a Multi-Theory Model (MTM)-based AI agent intervention for smoking cessation in early-stage cancer patients (clinical stage cTNM 0~II) who currently smoke.
- Conditions
- Smoking Cessation, Early-Stage Cancer, AI Agent
- Trial name
- NCT07827066
- Testing
- MTM-Based AI Agent for smoking cessation, Counseling
- Volunteers
- 156 people
- Sponsor
- Sun Yat-sen University
Interparental Conflict, Child Mental Health
Pilot Study of an Interparental Conflict Intervention for Separating or Divorcing Parents
This pilot study will evaluate a new intervention for parents who are separated or divorced and have been court ordered to participate in a program addressing interparental conflict.
- Trial name
- NCT07816445
- Testing
- Family COMPASS, Families in Transition (FIT)
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Arizona State University
Compulsive Sexual Behavior
Yoga Intervention for Compulsive Sexual Behavior Disorder
Yoga intervention as a complementary and integrative treatment for compulsive sexual behavior disorder (CSBD). The hypothesis is that participants with CSBD, after being submitted to the protocol of the yoga intervention group in…
- Trial name
- CSBD (NCT04634175)
- Testing
- Yoga intervention
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
Work-Related Musculoskeletal Disorders
The Impact of Back-supporting Exoskeletons for Manual Order Picking in Danish Warehouses - The RELAX Project
This study investigates the long-term effects of implementing a passive back-support exoskeleton during manual order-picking work in a real-world warehouse environment.
- Trial name
- RELAX (NCT07561112)
- Testing
- Use of an occupational passive back-exoskeleton
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Breast Carcinoma, Cervical Carcinoma
The Ohio State University (OSU) SCREEN Community Program
This clinical trial develops and tests how well a multi-level intervention (MLI), The Ohio State University (OSU) SCREEN Community Program, works to increase screening and follow-up for breast, cervical and colorectal (CRC)…
- Conditions
- Breast Carcinoma, Cervical Carcinoma, Colorectal Carcinoma
- Trial name
- NCT06666192
- Testing
- Cancer Screening, Discussion, Educational Activity
- Where
- United States
- Volunteers
- 2,067 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Encopresis, ASD
Comprehensive Toileting Program
The current study aims to monitor fecal continence after autistic youth complete enuresis treatment and for individuals who continue to experience encopresis after acquiring urine continence, evaluate a caregiver-mediated version…
- Trial name
- NCT07226739
- Testing
- Glycerin Suppository, Behavioral strategies
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Emory University
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