Clinical trials: For Intervention
Bipolar Disorder, Major Depression
Effectiveness of mHealth Post-discharge Intervention for Patients With Severe Mental Illness
The overall aim of this program of research is to improve the continuity of care for patients with serious mental illness (SMI) by supporting a safer and more efficient bridge from hospital to outpatient care using a mobile…
- Conditions
- Bipolar Disorder, Major Depression, Schizophrenia
- Trial name
- tFOCUS (NCT05703412)
- Testing
- Transition-FOCUS mHealth Intervention, Check-In
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Butler Hospital
Femoral Vascular Anastomosis
Post-Marketing Surveillance of TISSUCOL for Hemostasis in Subjects Undergoing Vascular Reconstruction With Polytetrafluoroethylene (PTFE) Prosthesis
This study investigates if the time to hemostasis can be reduced by application of Tissucol® onto femoral vascular anastomoses with PTFE prostheses compared to standard methods, such as compression with swabs.
- Trial name
- NCT00163592
- Testing
- Tissucol®, Control: Conventional treatment, i.e. compression with swabs
- Where
- 5 sites in Austria, Germany
- Volunteers
- 60 people
- Sponsor
- Baxter Healthcare Corporation
Epidermolysis Bullosa
Allogeneic ABCB5-positive Dermal Mesenchymal Stromal Cells for Treatment of Epidermolysis Bullosa (Phase III)
The aim of this clinical trial is to investigate the safety and efficacy of allo-APZ2-OTS administered intravenously to subjects with recessive dystrophic epidermolysis bullosa (RDEB) compared to placebo.
- Trial name
- NCT05838092
- Testing
- allo-APZ2-OTS
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- RHEACELL GmbH & Co. KG
Mental Health
Cocreation and Evaluation of an Escape Game on Students' Mental Health
The Covid-19 pandemic and the protracted lockdowns have heavily impacted university students' mental health. Digital Escape Games represent a good means to reach students and propose them solutions for their psychological…
- Trial name
- EscapeCovid (NCT06720792)
- Testing
- EscapeCovid
- Where
- France
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- University of Bordeaux
Neuroaxial Analgesia Procedures
EPIDURAL- Evaluation of Preexisting Information Regarding Neuroaxial Procedures for Labour Analgesia
The aim of this research project is to anonymously survey pregnant patients before the anaesthesiological consultation about their prior knowledge of planned neuroaxial procedures in the context of childbirth by conducting an…
- Trial name
- EPIDURAL (NCT06201936)
- Testing
- Preliminary information on neuroaxial procedures
- Where
- Germany
- Volunteers
- 1,346 people
- Sponsor
- Goethe University
Sleep, Occupational Stress
A Proactive Intervention Promoting Strategies for Sleep and Recovery in Nurses
Considering the known challenges facing newly graduated nurses, there are possibilities to implement preventive actions. The aim of the current study was to evaluate the effects of a preventive intervention among newly graduated…
- Conditions
- Sleep, Occupational Stress, Fatigue, Behavior, Health
- Trial name
- NCT04246736
- Testing
- Bädda för Kvalitet
- Where
- 7 sites in Sweden
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Chronic Pain, Depression
A Behavioral Intervention for Depression and Chronic Pain in Primary Care (Relief-Hybrid)
Chronic pain and depression frequently co-exist in late and mid-life and contribute to increased disability, high health care costs, psychiatric comorbidity, and suicide.
- Trial name
- NCT04290845
- Testing
- Relief-Hybrid
- Where
- 4 sites in United States
- Sponsor
- Weill Medical College of Cornell University
Type 2 Diabetes Mellitus (T2DM), Insulin Resistance
Validation of the Snouda Metabolic Score for Phenotyping and Guiding Reversal in Type 2 Diabetes
This study tests a new tool called the Snouda Metabolic Score (SMS) that helps doctors identify the specific metabolic problems driving Type 2 Diabetes in each individual patient.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Insulin Resistance, Metabolic Syndrome
- Trial name
- SMS-VAL (NCT07606872)
- Testing
- Phenotype-Matched Dietary Protocol, Structured Progressive Exercise Protocol, Targeted Nutritional Supplementation
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- Salah Snouda
Stress, Psychological, Mental Health Wellness
Pilot Testing of a Structural Racism Intervention for Immigrant Latinx Families
The purpose of this study is to evaluate a new, community-based, group intervention called FIESTA (Familias Inmigrantes Empoderándose contra eStrés Tomando Acción) to understand how well it helps Latinx immigrant families deal…
- Trial name
- NCT05991739
- Testing
- Familias Inmigrantes Empoderándose contra eStrés Tomando Acción (FIESTA)
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Suicide, Attempted
Teachable Moment Brief Intervention for Veterans Following a Suicide Attempt
The overall objective is to determine the acceptability and feasibility of the Teachable Moment Brief Intervention (TMBI) + follow-up consultation for Veterans treated on an inpatient psychiatry unit following a suicide attempt.
- Trial name
- NCT03533075
- Testing
- Teachable Moment Brief Intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Louisville VA Medical Center
Facilatated STAIR Coach
Use of Facilitated STAIR Coach in Kenya
The specific aim of this project is to examine the feasibility of using a low cost, low intensity, mobile app-based intervention teaching emotion regulation and interpersonal skills to improve general well-being for those with…
- Trial name
- NCT06476457
- Testing
- STAIR Coach
- Volunteers
- 10 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
Autism Spectrum Disorder, Autism
Investigation of Mechanisms of Action in Superpower Glass
The following study aims to understand the mechanism of action at work in a novel artificial intelligence (AI) tool that runs on Google Glass through an Android app to deliver social emotion cues to children with autism during…
- Trial name
- NCT04049981
- Testing
- Superpower Glass
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Stanford University
Psychological Stress
Mobile Stress Management Program for African American Women
The unjust social, economic, and environmental conditions that African Americans face throughout their lives lead to pervasive health disparities. These disparities are driven by healthcare differences.
- Trial name
- NCT04863781
- Testing
- Mobile cognitive-behavioral stress management intervention, Control
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- ISA Associates, Inc.
Coronary Artery Disease
PREventive Invasive Strategy for Obstructive Coronary Artery Disease With Vulnerable Plaque Evaluated by CoroNary Computed Tomography Angiography-2
The PREVENT-2 trial is to determine whether an initial invasive strategy-consisting of early coronary angiography (CAG) with intent for preventive percutaneous coronary intervention (PCI) in addition to optimal medical therapy…
- Trial name
- PREVENT-2 (NCT07569692)
- Testing
- Initial Invasive Strategy, Initial Conservative Strategy
- Where
- South Korea
- Volunteers
- 2,500 people
- Sponsor
- Duk-Woo Park, MD
Myocardial Infarction
Exenatide for Myocardial Protection During Reperfusion Study
This study aims to assess the effect of exenatide on myocardial injury in patients undergoing emergent percutaneous coronary intervention (PCI) for ST segment elevation myocardial infarction or heart attack (STEMI).
- Trial name
- EMPRES (NCT01938235)
- Testing
- Exenatide
- Where
- 10 sites in Canada
- Volunteers
- 198 people
- Sponsor
- University Health Network, Toronto
Stress Disorders, Post-Traumatic
Mind-Body Intervention for Veterans With PTSD
This pilot project evaluates the efficacy of a mind-body awareness training intervention, Mind-Body Bridging (MBB), in veteran patients with PTSD and comorbid symptoms.
- Trial name
- NCT02224989
- Testing
- Mind-Body Bridging
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Utah
Healthy Adults, Stress
Breathing Interventions for Relaxation: Dosing Through Extended Exhale
Breathing exercises are categorized as a mind-body practice. One in ten adults in the U.S. use breathing exercises for health purposes.
- Trial name
- NCT02870868
- Testing
- Slow breathing
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Postoperative Ileus
Anti-inflammatory Effect of Pre-operative Stimulation of the Cholinergic Anti-Inflammatory Pathway
Hypothesis: Prucalopride can mimic electrical stimulation of the abdominal vagus nerve and has an anti-inflammatory effect. Aims: In the present pilot study, the investigators want to evaluate the anti-inflammatory effect of…
- Trial name
- NCT02425774
- Testing
- Vagus stimulation, Prucalopride
- Where
- Belgium
- Volunteers
- 31 people
- Sponsor
- KU Leuven
Self-harm
Suicide Prevention by Empowering Adolescents in Pakistan (SEPAK)
Self-harm is now seen as an epidemic affecting young people across the world and particularly in low and middle-income countries (LMIC) such as Pakistan.
- Trial name
- SEPAK (NCT04969718)
- Testing
- LEADS Plus educational posters, Question, Persuade, and Refer (Teachers) Plus educational posters, Screening by Professionals programme plus educational posters
- Where
- 8 sites in Pakistan
- Volunteers
- 1,350 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Living and Learning
Bipolar Disorder
Development of a Personalized Real-time Intervention for Bipolar Disorder
This three-year intervention development proposal is submitted to the NIMH DATR Mood Disorders/Sleep Disorders Program A2-AID and is led by a New Investigator.
- Trial name
- PRISM (NCT01670123)
- Testing
- Personalized Real-Time Intervention for Stabilizing Mood
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of California, San Diego
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