Clinical trials: For Intervention
Myopia
Use of the VisuMax™ Femtosecond Laser
The objective of this clinical trial is to evaluate the safety and effectiveness of the Carl Zeiss Meditec VisuMax™ Femtosecond Laser lenticule removal procedure for the reduction or elimination of myopia from ≥ -1.00 D to ≤…
- Trial name
- NCT01638390
- Testing
- Treatment with the VisuMax™ Femtosecond Laser
- Where
- 5 sites in United States
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Cancer Patients, Family Caregivers
A Study Comparing Two Types of Supportive Interventions for Caregivers of Patients With Cancer
The purpose of this study is to compare two types of therapy for caregivers of cancer patients: Emotion Regulation Therapy for Cancer Caregivers (ERT-C) and Cognitive Behavioral Therapy (CBT-C).
- Trial name
- NCT04802720
- Testing
- Cognitive Behavioral Therapy for Cancer Caregivers (CBT-C), Emotion Regulation Therapy for Cancer Caregivers (ERT-C)
- Where
- 5 sites in United States
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Language Delay, Language Development Disorders
Vocabulary Intervention for Late Talkers
Most studies regarding word learning have focused on understanding when and how infants learn words. At 24 months, typically developing infants know between 200 and 300 words and add new words to their vocabularies at a rapid…
- Trial name
- NCT03379818
- Testing
- Shape training intervention, Specific word training
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Birmingham
Smoking
Tobacco Tactics Website for Veteran Smokers
The purpose of this study is to develop an evidence-based Tobacco Tactics website tailored to veterans based on an intervention tested in the VA.
- Trial name
- NCT00665704
- Testing
- Tobacco Tactics website
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- US Department of Veterans Affairs
Social Anxiety Disorder (SAD)
A Randomized, Controlled Study of Two At-Home Self-Guided Virtual Reality Interventions for Adults With Social Anxiety Disorder.
This study is to compare two Virtual Reality (VR)-based interventions, BVR-100 and BES-100, for the treatment of Social Anxiety Disorder (SAD).
- Trial name
- BVR-100-102 (NCT06037668)
- Testing
- BVR-100, BES-100
- Where
- 6 sites in United States
- Volunteers
- 56 people
- Sponsor
- Sumitomo Pharma America, Inc.
PTSD
Evaluation of Web-Based CBT for Women Veterans With PTSD
The purpose of this study is to evaluate an online PTSD intervention that was adapted for women Veterans, called DElivery of Self TRaining and Education for Stressful Situations-Women Veterans version (DESTRESS-WV).
- Trial name
- NCT02917447
- Testing
- DESTRESS-WV, Phone Monitoring
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- VA Office of Research and Development
Congestive Heart Failure
Health Literacy in Patients With Congestive Heart Failure
The primary aim of this project is to test the efficacy of an inpatient congestive heart failure (CHF) educational intervention compared with usual care among inpatients at Griffin Hospital, who are largely drawn from the…
- Trial name
- NCT00508716
- Testing
- Health Literacy-Tailored Education
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Griffin Hospital
Long COVID-19, Long COVID
RECOVER-VITAL: Platform Protocol, Appendix to Measure the Effects of Paxlovid on Long COVID Symptoms
This is an appendix of master protocol (NCT05595369) designed to be flexible so that it is suitable for a wide range of settings within health care systems and in community settings where it can be integrated into COVID-19…
- Trial name
- RECOVER-VITAL (NCT05965726)
- Testing
- Paxlovid, Ritonavir
- Where
- United States
- Volunteers
- 964 people
- Sponsor
- Kanecia Obie Zimmerman
Attention Deficit Hyperactivity Disorder
Intervention for Teens With ADHD and Substance Use
Individuals with ADHD are at markedly high risk for increased substance use and Substance Use Disorder (SUD). Given the strong evidence for the negative trajectory of individuals with co-occurring ADHD and substance use…
- Trial name
- NCT02502799
- Testing
- Brief Early Intervention, Parent Training with Adolescent Cognitive Behavioral Therapy, Methylphenidate
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- Florida International University
Alcohol Use Disorder, Alcohol Dependence
RCT of Web-Based Behavioral Sleep Intervention for Individuals With Alcohol Use Disorder
Background: Many people with alcohol use disorders have a sleep problem called insomnia. One treatment is Cognitive Behavioral Therapy for Insomnia (CBT-I).
- Conditions
- Alcohol Use Disorder, Alcohol Dependence, Insomnia
- Trial name
- NCT03493958
- Testing
- Sleep Healthy Using the Internet (SHUTi)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Mindfulness-based Intervention for Preschoolers
Effects of Mindfulness Training on the Psychological Well-being of Preschoolers
The present study is a randomized controlled trial to evaluate the effectiveness of a mindfulness course on the psychological well-being of preschoolers (i.e., attention and impulsivity, prosocial behavior, empathy, emotion…
- Trial name
- NCT05058365
- Testing
- dots Curriculum
- Where
- Hong Kong
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Infants With or at Risk/Concern for Developmental Delay
Otteroo Case Series
Rationale. The Otteroo is a floatie which supports an infant or young child with their head above and their body in water. Researchers are proposing that the Otteroo may be a good "tool" to facilitate exploring the ability to…
- Trial name
- NCT03502265
- Testing
- Otteroo
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Southern California
Mental Health Issue, Emotional Stress
DISCOVER Workshop Programme for Care Experienced Young People
The NHS DISCOVER team has secured 2-year funding from the Maudsley Charity to tailor the workshop programme the investigators deliver in school Sixth Forms to meet the specific needs of Care Experienced young people.
- Conditions
- Mental Health Issue, Emotional Stress, Emotional Regulation
- Trial name
- NCT05220436
- Testing
- DISCOVER workshop programme
- Where
- 2 sites in United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- South London and Maudsley NHS Foundation Trust
Colorectal Neoplasms
Evaluating a Preference-based Intervention for Increasing Colorectal Cancer Screening
The goal of this study is to evaluate whether an educational tool about colorectal cancer (CRC) completed on a computer that helps patients clarify their CRC screening preferences will lead to increased screening rates for CRC…
- Trial name
- EPIIC (NCT00810771)
- Testing
- Standard Information, Preference-tailored Information
- Where
- 2 sites in United States
- Volunteers
- 466 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Smoking Cessation, Obesity
A Multiple Health Behavior Change Intervention for Overweight and Obese Smokers
The purpose of this study is to determine the efficacy, acceptability, and feasibility of an intervention that provides a behavioral weight gain prevention intervention in advance of smoking cessation treatment in individuals…
- Trial name
- NCT05136430
- Testing
- Self-Regulation strategies + large changes (SR), Healthy Lifestyle Education (LE), Smoking Cessation Treatment
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Brown University
Schizophrenia, Psychotic Disorders
A Brief Community Linkage Intervention for Dually Diagnosed Individuals
Surveys suggest that up to 80% of veterans with a persistent mental illness have a co-occurring substance use disorder. Substance abuse among this population is problematic and often results in poor engagement in treatment and…
- Conditions
- Schizophrenia, Psychotic Disorders, Substance-Related Disorders, Bipolar Disorder
- Trial name
- TLC (NCT00137267)
- Testing
- Time limited case management, Health Education
- Where
- 2 sites in United States
- Volunteers
- 102 people
- Sponsor
- US Department of Veterans Affairs
Burnout, Stress
Inner Engineering Online (IEO) Intervention for a Specific Company Employee Program
In this randomized controlled trial; differences in overall stress, burnout and wellbeing will be assessed for employees of a company participating in Inner Engineering Online, an online mind-body course that incorporates both…
- Conditions
- Burnout, Stress, Depression, Anxiety
- Trial name
- NCT04126564
- Testing
- Inner Engineering Online, Reading a book/ journal
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Cancer, Coping Skills
Mind-body Resiliency Intervention for Fear of Cancer Recurrence
The purpose of this study is to test the feasibility of a virtual, group mind-body resiliency intervention adapted to target fear of recurrence (FOR) among cancer survivors.
- Conditions
- Cancer, Coping Skills, Coping Behavior
- Trial name
- NCT04876599
- Testing
- IN FOCUS, Usual Care
- Where
- 5 sites in United States
- Volunteers
- 64 people
- Sponsor
- Massachusetts General Hospital
Suicide Prevention
Brief Suicide Intervention for Youth in Juvenile Detention Settings
This is an intervention development study and therefore is not designed or powered to test hypotheses. Following initial development and refinement of intervention and protocol, an open trial will be conducted at one juvenile…
- Trial name
- NCT05225103
- Testing
- SAFETY-Acute intervention
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Duke University
Peer Influence
Penetrating the Classroom Social Network for Children With Language Impairment Via Peer Mediated Intervention
This exploratory experiment is designed to determine the extent to which the socialization experiences and social, behavioral, and linguistic skills of preschoolers with language impairment (LI) can be improved.
- Trial name
- PEERS (NCT06182033)
- Testing
- Peer-mediated pivotal response training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Ohio State University
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