Clinical trials: For Intervention
Parenting, Substance Use
A Substance Use Adaptation of Fathering Through Change
This study is a randomized control trial of the Fathering Through Change intervention, delivered via text messaging, to fathers in recovery for substance use disorders.
- Trial name
- FTC-SUD (NCT04532619)
- Testing
- Fathering Through Change
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Suicide
Suicide Prevention Intervention for Vulnerable Emerging Adult Sexual Minorities
Emerging adult sexual minorities (EASM) are vulnerable to stressors that increase risk for suicidal ideation and behaviors. The investigators will examine a mobile application that leverages skills coaching and peer mentoring to…
- Trial name
- NCT05018143
- Testing
- STARS, Control condition
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Pennsylvania
Dementia, Familial
Developing and Testing the Enhancing Active Caregiver Training (EnACT) Intervention for Dementia Family Caregivers
Persons with Alzheimer's disease and related dementias (ADRD) experience behavioral symptoms such as agitation, combativeness, depression, and apathy.
- Trial name
- EnACT (NCT04920006)
- Testing
- Enhancing Active Caregiver Training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Utah
Fetal Alcohol Spectrum Disorders
Study of the Families Moving Forward Website Behavioral Intervention for Teachers of Students With Fetal Alcohol Spectrum Disorder
The purpose of this study is to find out if the FMF Connect Teacher Companion website is acceptable and usable by teachers. The FMF Connect Teacher Companion website is a website for teachers adapted from the Families Moving…
- Trial name
- NCT05986565
- Testing
- Families Moving Forward (FMF) Teacher adapted training
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Bone Marrow Edema, Knee Pain Chronic
Subchondroplasty® Knee RCT
This is a multi-center, prospective, single-blinded, two-arm study, randomized to include approximately 134 subjects treated with Subchondroplasty (SCP) + Arthroscopy and 67 subjects with arthroscopy alone.
- Conditions
- Bone Marrow Edema, Knee Pain Chronic, Knee Osteoarthritis, Osteoarthritis, Knee
- Trial name
- PRESERVE Knee (NCT03112200)
- Testing
- Subchondroplasty with Arthroscopy, Arthroscopy Alone
- Where
- 13 sites in United States, Canada
- Volunteers
- 131 people
- Sponsor
- Zimmer Biomet
Hematologic Malignancy, Hematopoietic/Lymphoid Cancer
Positive Psychology Intervention In HSCT
The main purpose of this research study is to determine if a positive psychology-based program in people who have received a stem cell transplant for blood cancer treatment is feasible and acceptable, and can help improve…
- Conditions
- Hematologic Malignancy, Hematopoietic/Lymphoid Cancer, Blood Cancer
- Trial name
- PATH-3 (NCT05147311)
- Testing
- Positive Psychology Intervention
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Brigham and Women's Hospital
Food Insecurity
CommunityRx-Hunger
CommunityRx-Hunger (CRx-H) is a hospital-based intervention that addresses food insecurity and other health-related social needs such as transportation, housing, utilities, and safety.
- Trial name
- CRx-H (NCT04171999)
- Testing
- Community Rx-Hunger (CRx-H)
- Where
- United States
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Breast Screening
Are Text Message Reminders an Effective Intervention for Improving the Uptake of Breast Screening?
Breast Cancer is the single most common cancer, and the third leading cause of cancer cancer deaths, in the United Kingdom. Breast screening is able to detect breast cancer in the early stages of development, during which time it…
- Trial name
- NCT01977599
- Testing
- Text Message Reminder for Breast Screening Appointment
- Where
- United Kingdom
- Volunteers
- 2,240 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Insomnia
Implementing Sleep Interventions for Older Veterans
Sleep problems are common among older people, and research suggests that insomnia has negative effects on health and quality of life in older adults.
- Trial name
- NCT00781963
- Testing
- Manual-based cognitive behavioral therapy for insomnia, Non-directive sleep education
- Where
- United States
- Volunteers
- 519 people
- Sponsor
- VA Office of Research and Development
PRU(Platelet Reactivity Unit), APT(Antiplatelet Therapy)
Platelet Reactivity (High On-Treatment Platelet Reactivity) as Guidance for APT (Antiplatelet Therapy) Adjustment After PCI (Percutaneous Coronary Intervention)
Since thrombus formation is a very complex procedure in vivo, platelet function testing methods in vitro might only reflect the degree of inhibition of platelet from a certain level, which do't reflect the functional status of…
- Conditions
- PRU(Platelet Reactivity Unit), APT(Antiplatelet Therapy), HOTPR(High on Treat Platelet Reactivity)
- Trial name
- NCT02101411
- Testing
- PRU(Platelet reactivity unit)
- Where
- Taiwan
- Volunteers
- 334 people
- Sponsor
- Taipei City Hospital
PTSD
Evaluation of Web-Based CBT for Women Veterans With PTSD
The purpose of this study is to evaluate an online PTSD intervention that was adapted for women Veterans, called DElivery of Self TRaining and Education for Stressful Situations-Women Veterans version (DESTRESS-WV).
- Trial name
- NCT02917447
- Testing
- DESTRESS-WV, Phone Monitoring
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- VA Office of Research and Development
Cannabis Use
Social Media Intervention for Cannabis Use in Emerging Adults
The purpose of the study is to develop and test social media interventions to help young people increase well-being and reduce risky behaviors.
- Trial name
- NCT04187989
- Testing
- Social Media Intervention
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- University of Michigan
Hepatitis C, People Who Inject Drugs
Accessible HCV Care Intervention for People Who Inject Illicit Drugs (PWID)
The proposed study will examine the feasibility, acceptability, safety, effectiveness, and cost of an Accessible Care intervention for engaging people who inject illicit drugs (PWID) in hepatitis C care.
- Conditions
- Hepatitis C, People Who Inject Drugs, PWID, HCV Coinfection
- Trial name
- NCT03214679
- Testing
- Accessible Care, Usual Care
- Where
- United States
- Volunteers
- 167 people
- Sponsor
- City University of New York, School of Public Health
Tourette Disorder, Chronic Tic Disorder
Augmentation of Brief Habit Reversal Training With D-cycloserine or Placebo
Expert reviews and practice parameter papers recommend behavior therapy as a first-line intervention for youth with chronic tic disorders (CTDs) with mild-to-moderate tic severity.
- Trial name
- DCS+HRT (NCT02582515)
- Testing
- D-cycloserine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Los Angeles
Cancer
A Stress Management and Resiliency Program for Adolescent and Young Adult Survivors
This research study aims to explore the feasibility and acceptability of an adapted resiliency group program, called the Relaxation Response Resiliency Program (3RP-AYA), to reduce stress and promote stress-management among…
- Trial name
- NCT03768336
- Testing
- Waitlist control, 3RP-AYA
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder
Oxytocin and Social Cognitive Skills Groups
The purpose of this study is to evaluate the feasibility, safety, and preliminary efficacy of integrating targeted dosing of intranasal oxytocin with a social cognitive skills group therapy for school-aged children with autism…
- Trial name
- ION-ASD (NCT02918864)
- Testing
- Oxytocin, Social Cognitive Skills Training, Facilitated Play Therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Rush University Medical Center
PTSD, Physical Injury
IT Enhanced Peer Integrated Collaborative Care for US Trauma Care Systems
This study evaluates two readily implementable approaches to the delivery of transitional care for injured patients treated emergently in US trauma care systems.
- Trial name
- TSOS 7 Peer (NCT03569878)
- Testing
- Peer-Integrated Multidisciplinary Collaborative Care, Trauma surgery team notification
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- University of Washington
Hepatitis C, Medication Adherence
Patient-Centered Models of HCV Care for People Who Inject Drugs
People who inject drugs (PWID) have higher rates of hepatitis C virus (HCV) than do other groups. Effective, safe new treatments called direct-acting antiviral agents (DAAs) have been developed recently.
- Trial name
- HERO (NCT02824640)
- Testing
- Patient Navigation, modified Directly Observed Therapy
- Where
- United States
- Volunteers
- 755 people
- Sponsor
- Prisma Health-Upstate
Migraine
A Study With Lu AG09222 in Adults With Migraine Who Have Not Been Helped by Prior Preventive Treatments
Researchers are trying to learn whether a drug called Lu AG09222 can help prevent migraine headaches for people who have not been helped by other treatments that are used to prevent migraines.
- Trial name
- NCT05133323
- Testing
- Lu AG09222
- Where
- 28 sites in United States, Czechia and 4 more
- Volunteers
- 237 people
- Sponsor
- H. Lundbeck A/S
Spinal Cord Injuries
TENS Trial to Prevent Neuropathic Pain in SCI
The purpose of this research study is to: 1) test whether transcutaneous electrical nerve stimulation (TENS) after spinal cord injury can reduce the onset of post-injury neuropathic pain; and 2) to learn more about this kind of…
- Trial name
- TENS (NCT03267810)
- Testing
- TENS
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Miami
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