Clinical trials: For Intervention
Type 1 Diabetes, Latent Autoimmune Diabetes in Adults
Digital Exercise for Middle-Aged Adults With Type 1 Diabetes and Other Absolute Insulin Deficiency Diabetes
The challenges of living with type 1 diabetes often stand in the way of getting enough exercise. Continuous blood sugar monitoring has revolutionized type 1 diabetes care but remains underutilized to sustainably support exercise…
- Conditions
- Type 1 Diabetes, Latent Autoimmune Diabetes in Adults, Pancreatitis
- Trial name
- NCT06098729
- Testing
- Digital Exercise
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Yale University
HIV
Mobile Health Intervention to Increase HIV Testing and Linkage to Care
This 5-year project will test an mobile health approach to improve HIV self-testing (HST) and linkage to HIV-related care among high-risk men in China.
- Trial name
- NCT05484895
- Testing
- WeTest-WeLink, Control condition
- Where
- 3 sites in China
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Emory University
Benign Prostatic Hypertrophy Requiring Surgical Intervention
Randomized Controlled Trial Comparing Two Different Morcellators for HoLEP Procedures
To compare efficiency, in terms of tissue morcellation and removal time, of two commercially available FDA-approved morcellators: the VersaCut and the Piranha in subjects undergoing HoLEP procedure for benign prostatic…
- Trial name
- NCT02195622
- Testing
- Lumenis VersaCut Morcellator, Wolf Piranha Morcellator
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Indiana Kidney Stone Institute
Type 1 Diabetes
Technology-delivered Physical Activity Program for Adolescents With Type 1 Diabetes
This project is comprised of a two-arm randomized control trial (RCT) testing the feasibility, acceptability, and preliminary efficacy of a nationally scalable program, Activate, a 12-week, technology-delivered diabetes…
- Trial name
- Activate (NCT05319600)
- Testing
- Diabetes behavior change skills training, Physical activity promotion program
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Vermont
CHF, COPD
A Technology Assisted Care Transition Intervention for Veterans With CHF or COPD
Transition from hospital to home places patients in jeopardy of adverse events and increases their risk for rehospitalization. CHF is the most prevalent chronic condition among U.S.
- Trial name
- TACT (NCT02632552)
- Testing
- Technology-assisted care transition intervention, Active attention control
- Where
- 5 sites in United States
- Volunteers
- 140 people
- Sponsor
- VA Office of Research and Development
Dental Anxiety
Efficacy of an Internet-based Intervention for Dental Anxiety
The overall objective of the activities described in this protocol is to examine the efficacy of the Internet-based intervention in the reduction of dental anxiety in patients seeking dental treatment.
- Trial name
- NCT03680755
- Testing
- Internet-based intervention for dental anxiety
- Where
- United States
- Volunteers
- 503 people
- Sponsor
- Temple University
Alcohol Drinking, Pain
Personalized Feedback Intervention for Alcohol and Opioid Use Among Adults With Chronic Pain
Over one-quarter of American adults engage in hazardous drinking (i.e., a pattern of alcohol consumption that increases risk for harmful consequences), which is the third leading cause of preventable death in the U.S.
- Conditions
- Alcohol Drinking, Pain, Opioid Use, Feedback, Psychological
- Trial name
- NCT04592978
- Testing
- Pain-Alcohol Personalized Feeback Intervention, Control Personalized Feedback Intervention
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- Syracuse University
Kidney Transplant
Mycophenolate Mofetil and Rapamycin as Secondary Intervention vs. Continuation of Calcineurin Inhibitors in Patients at Risk for Chronic Renal Allograft Failure
A study to determine the effect on renal function in renal transplant patients with biopsy proven Chronic allograft nephropathy (CAN) nephropathy who are switched from a Calcinerin inhibitor (CI) triple drug regimen to a…
- Trial name
- NCT00223678
- Testing
- Rapamycin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Vanderbilt University Medical Center
Elder Abuse
Feasibility of VOICES Elder Abuse Intervention in Primary Care Setting (VOICES-PC Feasibility)
To test an interactive intervention to screen for Elder Abuse and Mistreatment (EM) in the Primary Care (PC) setting to promote self-identification and self-disclosure of EM.
- Trial name
- VOICES-PC (NCT05224843)
- Testing
- Virtual cOaching in making Informed Choices on Elder Mistreatment Self-Disclosure (VOICES)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yale University
Surgical Wound
VASCADE ANTEGRADE-PVD Post-Market Registry
The objective of the registry is to collect procedural outcomes data when the Cardiva VASCADE Vascular Closure System (VCS) is used to seal femoral arterial access sites at the completion of ipsilateral peripheral interventional…
- Trial name
- NCT02948257
- Testing
- Cardiva Medical VASCADE VCS
- Where
- 5 sites in United States
- Volunteers
- 52 people
- Sponsor
- Cardiva Medical, Inc.
Non ST Segment Elevation Acute Coronary Syndrome
Different LD of Ticagrelor for Antiplatelet Effect in Patients With Non-ST-segment Elevation ACS Undergoing PCI
It is designed to test the hypothesis that high loading dose(360mg) ticagrelor versus conventional loading dose(180mg) will result in a higher inhibition of platelet aggregation(IPA) without increasing the bleeding events.
- Trial name
- NCT01962428
- Testing
- ticagrelor
- Where
- 2 sites in China
- Volunteers
- 250 people
- Sponsor
- General Hospital of Chinese Armed Police Forces
HIV, Violence, Gender-Based
Supporting Trans Affirmation, Relationships, and Sex, Phase 3
The purpose of this clinical trial is to evaluate and test a newly developed gender-affirming intervention that addresses the dual and interconnected risks of HIV and intimate partner victimization (IPV) among transgender women…
- Conditions
- HIV, Violence, Gender-Based, Violence, Domestic, Risk Reduction Behavior
- Trial name
- STARS (NCT06001307)
- Testing
- Program STARS (Supporting Trans Affirmation, relationships, and Sex), Relaxation and Stress Reduction
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Brown University
Pneumothorax
Bio-Seal Biopsy Track Plug for Reducing Pneumothorax Rates Post Lung Biopsy Procedure
BS-1053 A Prospective Randomized Multi-Centered Safety and Efficacy Evaluation of the Bio-Seal Biopsy Track Plug for Reducing Pneumothorax Rates Post Lung Biopsy Procedures
- Trial name
- NCT00562302
- Testing
- Bio-Seal Plug
- Where
- 18 sites in United States
- Volunteers
- 339 people
- Sponsor
- Angiotech Pharmaceuticals
Cognitive Aging
Intervention Comparative Effectiveness for Adult Cognitive Training
The study will compare the effect of broad and directed (narrow) technology-based training on basic perceptual and cognitive abilities in older adults and on the performance of simulated tasks of daily living including driving…
- Trial name
- ICE-ACT (NCT03141281)
- Testing
- BrainHQ, Rise of Nations, IADL Training
- Where
- United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Florida State University
Cardiac Surgery, Older Adults
Behavioral Activation and Medication Optimization In Older Adults Undergoing Cardiac Procedures
This Hybrid 1 Study will test the effectiveness of a bundled intervention comprised of behavioral activation and medication optimization in reducing symptoms of depression and anxiety in older adults undergoing cardiac surgery…
- Conditions
- Cardiac Surgery, Older Adults, Depression, Anxiety
- Trial name
- NCT05575128
- Testing
- Behavioral activation, Medication optimzation, Care as usual
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Washington University School of Medicine
Motor Activity
Motor Imagery Intervention for Improving Gait and Cognition in the Elderly
The investigators propose a single-blind randomized clinical trial to determine if seniors show improved mobility (walking speed) and cognition following motor imagery (imagined walking) training.
- Trial name
- NCT02762604
- Testing
- Imagined Gait Intervention, Visual Imagery Intervention
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Anxiety Disorders
Developing a Low-Intensity Primary Care Intervention for Anxiety Disorders (AIM-PC)
The purpose of the study is to develop a personalized, user-friendly computerized treatment for anxiety disorders linked to primary care.
- Trial name
- NCT02579915
- Testing
- FaceAnxiety, Symptom Tracking
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Brown University
Significant Bleeding Risk
Study of Octaplex, a Four-factor Prothrombin Complex Concentrate (4F-PCC) and Beriplex® P/N (Kcentra) for the Reversal of Vitamin K Antagonist (VKA) Induced Anticoagulation in Patients Needing Urgent Surgery With Significant Bleeding Risk.
To demonstrate that the efficacy of OCTAPLEX as a reversal agent in patients under Vitamin K Antagonist (VKA) therapy with the need for urgent surgery with significant bleeding risk is clinically non-inferior to that Beriplex®…
- Trial name
- NCT02740335
- Testing
- Octaplex, Beriplex P/N (Kcentra)
- Where
- 86 sites in United States, Belarus and 9 more
- Volunteers
- 208 people
- Sponsor
- Octapharma
Multiple Sclerosis
A Positive Psychology Intervention for Patients With Multiple Sclerosis
Positive psychology (PP) uses targeted activities to increase the frequency and intensity of positive emotional experiences such as positive affect.
- Trial name
- NCT03637699
- Testing
- Positive Psychology
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Brigham and Women's Hospital
Subjective Cognitive Decline
DEMA-Pro Intervention for Seniors With Subjective Cognitive Decline and Living at Home
More than 4.4 million patients receive home health services following discharge from the hospital or rehabilitation facility. A substantial number (70%) are older adults with subjective cognitive decline (SCD), an early clinical…
- Trial name
- NCT04796415
- Testing
- the DEMA-Pro intervention
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Indiana University
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