Clinical trials: For Intervention
Percutaneous Intervention Via Femoral Artery
Star-Close Versus Angio-Seal for Femoral Artery Hemostasis
This study was designed to evaluate the efficacy and safety of Starclose (Abbott Vascular Devices) for femoral access site closure in patients undergoing PCI compared to Angio-Seal STS Plus (St. Jude Medical).
- Trial name
- CLOSE (NCT00590356)
- Testing
- StarClose®, AngioSeal®
- Where
- South Korea
- Sponsor
- Seung-Jung Park
Mood
The Safety and Efficacy of MoodElite T-4003-1 on Improving Mood in a Healthy Adult Population With Mild to Moderate Depressive Symptoms Not Eligible for Therapeutic Intervention
The objective of this study is to investigate the efficacy and safety of MoodElite T-4003-1 on improving mood in a healthy adult population with mild to moderate depressive symptoms not eligible for therapeutic intervention.
- Trial name
- NCT05318456
- Testing
- MoodElite T-4003-1, Comparator
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- Chenland Nutritionals Inc.
PCOS
An Integrated Self-Management Intervention for Adolescents With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is the most common female endocrine disorder, affecting 7%-18% of reproductive-age women. Women with PCOS are at increased risk for a number of adverse physical and mental health outcomes.
- Trial name
- NCT03600337
- Testing
- Working to Optimize Wellness in Tees with PCOS (WOW)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Texas at Austin
Acquired Brain Injury, Mental Health Issue
Community-based Occupational Therapy Intervention on Mental Health for People With Acquired Brain Injury
The main purpose of this research project is to analyze the effectiveness of a Community-based Occupational Therapy Intervention on mental health for people with acquired brain injury.
- Trial name
- COT-MHABI (NCT04586842)
- Testing
- Community-based Occupational Therapy, Standard community-based intervention
- Where
- Spain
- Volunteers
- 134 people
- Sponsor
- Institut Guttmann
Caregiver Burden in Methamphetamine Use Disorder, Expressed Emotions in Caregivers
Effectiveness of Stress Management Training Program For Expressed Emotions in Caregivers of Drug Induced Psychosis Patients Specially Methamphetamine
The main purpose of this study is to evaluate the effectiveness of a Stress Management Training (SMT) program in reducing stress levels among caregivers of individuals suffering from methamphetamine ("ice") addiction and…
- Conditions
- Caregiver Burden in Methamphetamine Use Disorder, Expressed Emotions in Caregivers, Stress Cause Expressed Emotion and Burden
- Trial name
- NCT07714642
- Testing
- O'Connor's (2003) Stress Management Training
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Government College University Faisalabad
Lung Cancer
CT-Controlled Advanced Navigation Techniques for Transbronchial Pulmonary Lesion Access; Evaluation of Electromagnetic Navigation Based Diagnostic Yield
In this clinical trial we will investigate the diagnostic yield of a combination of commercially available imaging and navigation techniques for reaching peripheral lung lesions.
- Trial name
- CONTROL-E (NCT03355586)
- Testing
- Electromagnetic navigation
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Radboud University Medical Center
Pediatric Cancer Survivor, Survivorship
Digital Self-Management and Peer Mentoring Intervention
This study tests how helpful a digital self-management and peer mentoring program is to young adult survivors of childhood cancer to improve their ability to manage their survivorship care as they transition from pediatric to…
- Conditions
- Pediatric Cancer Survivor, Survivorship, Cancer
- Trial name
- NCT06763770
- Testing
- Managing Your Health (MYH), The Usual Care + Educational Control
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Rutgers, The State University of New Jersey
Anesthesia
Breath Monitoring of Propofol (Observational Study)
This trial investigates the relationship between concentrations of the anesthetic drug propofol in exhaled breath and blood in patients undergoing general anesthesia for elective surgery.
- Trial name
- NCT01892683
- Testing
- General anesthesia with propofol
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Attitudes Towards Tobacco Industry
A Brief Intervention Programme for TID
The brief RCT will be conducted in the form of a questionnaire survey, with two kinds of leaflets embedded in the same questionnaire.
- Trial name
- NCT03800966
- Testing
- Leaflet
- Where
- Hong Kong
- Volunteers
- 1,069 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Alzheimer Disease
Playful Multimodal Intervention, Monitoring and Decision Support for Activation of People With Alzheimer's Dementia
The worldwide prevalence of dementia is increasing. Pharmaceutical therapies, at the best, slow the degenerative process, observable in Alzheimer's disease (AD).
- Trial name
- M-AAL (NCT04628702)
- Testing
- tablet training
- Where
- Austria
- Volunteers
- 24 people
- Sponsor
- Medical University of Graz
Stroke, Brain Ischemia
Use of Dexmedetomidine in Acute Stroke and Cerebral Vasospasm Interventions
Dexmedetomidine is a unique sedative medication able to provide sedation without causing respiratory depression and maintaining neurological functions.
- Conditions
- Stroke, Brain Ischemia, Vasospasm, Intracranial, Hemorrhage, Intracranial
- Trial name
- NCT01845441
- Testing
- Dexmedetomidine, Fentanyl, Midazolam
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University Hospitals Cleveland Medical Center
ALS (Amyotrophic Lateral Sclerosis)
Non-invasive Brain Stimulation and Exercise Intervention for Patients With Motor Neuron Disease
Motor neuron disease (MND) is a progressive neurological disorder involving degeneration of motor neurons, leading to muscle weakness, speech and swallowing difficulties, and respiratory failure.
- Trial name
- NCT07067229
- Testing
- Personalized rTMS, Standard rTMS
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Chulalongkorn University
Cesarean Delivery Affecting Fetus, Labor Dystocia
Early Diagnosis and Intervention for Fetal Malposition in Active Labor and Its Impact on Mode of Delivery
The goal of this randomized trial is to test if changing a person's position in labor can increase the chances of delivering their baby vaginally.
- Conditions
- Cesarean Delivery Affecting Fetus, Labor Dystocia, Labor Complication
- Trial name
- NCT05881629
- Testing
- Maternal position change to side-lying lateral with peanut ball, Free maternal position
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Sex Behavior
Evaluation of Asdzáán Be'eená Teen Pregnancy and Substance Use Prevention Program for Native American Youth and Their Caregiver
The objective of this research study is to evaluate a culturally grounded program among American Indian (AI) female adolescents and their female caregivers.
- Trial name
- NCT04863729
- Testing
- Asdzaan Be'eena Program
- Where
- 2 sites in United States
- Volunteers
- 408 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
NEC, Necrotizing Enterocolitis
Study of Normal Intestinal Development and Disease in Premature and Term Neonates
Current research on early intestinal development is primarily performed in mouse models. While useful in many other ways, mouse models are not ideal for studying human intestine development as the timing of this process differs…
- Conditions
- NEC, Necrotizing Enterocolitis, Intestinal Disease, Human Development
- Trial name
- NiiCE (NCT06681129)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston Children's Hospital
HIV Infection
Evaluating a Microfinance Intervention for High Risk Women in Mongolia
The proposed study aims to test the feasibility and preliminary efficacy of a combined 4-session HIV sexual risk reduction (HIVSRR) and microfinance intervention (including 34 training session and matched savings) to reduce…
- Trial name
- NCT01861431
- Testing
- HIV Sexual Risk reduction, HIV Sexual Risk reduction plus Microfinance
- Where
- Mongolia
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Columbia University
Unplanned Use of Health Care Services
Telehealth Nursing Intervention for Children With Complex Health Care Needs (CCHCN)
The overall objective of this study is to evaluate the effectiveness of a telehealth care coordination and case management nursing intervention for children with complex special health care needs.
- Trial name
- NCT01328353
- Testing
- telehealth plus aprn triage
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- University of Minnesota
Knee Osteoarthritis
Post Market Clinical Follow-Up Study- EVOLUTION® Revision CCK
Sponsor is conducting this post market clinical follow-up (PMCF) study to evaluate the safety and efficacy of its EVOLUTION® Revision CCK Tibia and EVOLUTION® Revision CCK Femur with EVOLUTION® CCK Tibial inserts.
- Trial name
- NCT04145401
- Testing
- Revision Knee implants
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- MicroPort Orthopedics Inc.
Asthma
Feasibility Trial of a Mobile Adherence Tool for Adolescents With Asthma
The purpose of this study is to assess the feasibility of using a mobile health intervention to improve adherence to asthma medication among adolescents in an urban clinic setting.
- Trial name
- NCT02426801
- Testing
- Inhaler sensor, Mobile application for asthma adherence
- Volunteers
- 16 people
- Sponsor
- CoheroHealth
Pain
Remifentanil Versus Propofol for TCI Sedation of Patients Undergoing Gastrointestinal Endoscopic Procedures
The purpose of this study was to compare remifentanil and propofol for sedation of patients during endoscopic gastrointestinal procedures.
- Trial name
- NCT01746641
- Testing
- Remifentanil, Propofol
- Where
- Colombia
- Volunteers
- 69 people
- Sponsor
- Fundación Universitaria de Ciencias de la Salud
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