Clinical trials: For Intervention
Climate Change, Health Behavior / Well-Being
Promoting Interventions for Climate Change to Upscale Resilience in District Astore
The PICCTURE trial is a cluster randomized controlled study that will be conducted in District Astore, Pakistan, to evaluate the effectiveness of community-based interventions in improving resilience to climate-related hazards.
- Conditions
- Climate Change, Health Behavior / Well-Being, Disaster Planning
- Trial name
- PICCTURE (NCT07557199)
- Testing
- Community Interventions, Primary Healthcare Intervention
- Where
- Pakistan
- Volunteers
- 1,350 people
- Sponsor
- Dr Jai Kumar Das
Schizophrenia, Bipolar Disorder
Illness Management and Recovery (IMR) in Danish Community Mental Health Centres
The aim of this trial is to evaluate the effectiveness of the Illness Management and Recovery program for people diagnosed with schizophrenia or bipolar disorder in according to their level of functioning.
- Trial name
- IMR (NCT01361698)
- Testing
- Illness Management and Recovery (IMR)
- Where
- Denmark
- Volunteers
- 198 people
- Sponsor
- Amager Hospital
Crohn's Disease, Peritoneal Carcinomatosis With Intestinal Occlusion
CAre of Patients With PArenteral Nutrition At Home
This research aims to give an overview of a number of aspects related to the quality of care for adult patients on home parenteral nutrition.
- Conditions
- Crohn's Disease, Peritoneal Carcinomatosis With Intestinal Occlusion, Radiation Enteritis, Chronic Diarrhea
- Trial name
- CAPANAH (NCT01545063)
- Where
- 13 sites in Belgium
- Volunteers
- 39 people
- Sponsor
- KU Leuven
Sexual Behavior, Child Sexual Abuse Material (CSAM) Consumption
Scalable Technology for Online Prevention of Child Sexual Abuse (CSA) and CSA Materials
1. Summary The STOP-CSAM Study is a two-armed randomized controlled trial of a non-pharmacological Therapy Chat Service for prevention of Child Sexual Abuse (CSA) and Child Sexual Abuse Materials (CSAM) in self-referred and self…
- Conditions
- Sexual Behavior, Child Sexual Abuse Material (CSAM) Consumption, Behavioural Disorder, Behavior Problems
- Trial name
- STOP-CSAM (NCT06764901)
- Testing
- Online Therapy Chat Service (TCS)
- Where
- 2 sites in Germany, Spain
- Volunteers
- 180 people
- Sponsor
- Charite University, Berlin, Germany
Malnutrition, Dietary Modification
Basic Care Revisited: Early Nutrition Intervention for Outpatients
Early nursing nutrition intervention for outpatients in need of surgery Objective - To investigate the feasibility and effectiveness of screening and an early nursing intervention on malnutrition in outpatients in need for…
- Trial name
- BCR_N (NCT02440165)
- Testing
- Nursing nutrition intervention
- Where
- 2 sites in Netherlands
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Self Efficacy, Loneliness
New in Town-Internet Intervention for Migrants
New in Town is an internet intervention for migrants that aims at increasing social self-efficacy. The study aim is to evaluate its effectiveness.
- Conditions
- Self Efficacy, Loneliness, Social Skills
- Trial name
- NCT04088487
- Testing
- New in Town-Interner Intervention for Migrants
- Where
- Poland
- Volunteers
- 178 people
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Solid Tumor, Solid Tumor, Adult
Psychotherapy Intervention for Latinos With Adv Cancer
The purpose of this study is to adapt a counseling intervention called Meaning Centered Psychotherapy to make it culturally relevant for Latinos. Cancer affects patients and their loved ones.
- Conditions
- Solid Tumor, Solid Tumor, Adult, Solid Tumor, Unspecified, Adult
- Trial name
- NCT04537936
- Testing
- Meaning Centered Psychotherapy for Latinos, Functional Assessment of Cancer Therapy - Spiritual Well-Being Scale, Meaning Centered Psychotherapy for Latinos for Waitlist Control Patients
- Where
- 4 sites in United States, Puerto Rico
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
HIV
HIV Prevention and Care Interventions for Youth in Uganda
Several studies show that Adolescents and Young Adults (AYA) have poor outcomes along the entire Human Immunodeficiency Virus (HIV) prevention and care cascades compared to adults.
- Trial name
- HIPCY (NCT06474364)
- Testing
- Long-acting Cabotegravir injection, SEARCH-YOUTH
- Where
- Uganda
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- MU-JHU CARE
Spinal Cord Injuries, Cognitive Dysfunction
Early Intervention for Information Processing Speed Deficits in Acute SCI: A Pilot Study
This study seeks to conduct a pilot study to test whether a cognitive training program can improve processing speed abilities in individuals with acute traumatic spinal cord injury.
- Conditions
- Spinal Cord Injuries, Cognitive Dysfunction, Cognitive Impairment, Acute Spinal Cord Injury
- Trial name
- SCI-IQ (NCT06452264)
- Testing
- game-like computerized activities
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kessler Foundation
Pediatric Pain and Anxiety
Painful Procedures in the Emergency Department: A Distraction Intervention
This study is designed to assess the effectiveness of the video-based intervention over and above current standard practice for pain control in the pediatric emergency department (ED).
- Trial name
- ERPain (NCT00338364)
- Testing
- PAT
- Where
- Canada
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Breast Cancer
Decisional Aid Intervention for Women Considering Breast Reconstruction
This is an intervention development and pilot study whose purpose is to determine the feasibility and acceptability of the breast reconstruction decisional aid (BRDA) and provide preliminary data on its impact on decisional…
- Trial name
- BRDA (NCT01951534)
- Testing
- Breast Reconstruction Decisional Aid (BRDA), Usual Care
- Where
- 9 sites in United States
- Volunteers
- 56 people
- Sponsor
- Rutgers, The State University of New Jersey
Autism Spectrum Disorders
Water Competency Intervention in Autism
AquOTic is an evidence-based, occupational therapy-led intervention designed to enhance water competency and swim safety skills in children on the autism spectrum.
- Trial name
- NCT07076264
- Testing
- AquOTic
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Ohio State University
Chest Pain
A Care Management Intervention for Non-cardiac Chest Pain
The investigators developed and implemented an eight-week multicomponent care management intervention for non-cardiac chest pain. Team members including a cardiologist, nurse, and psychiatrist.
- Trial name
- NCCP (NCT04904198)
- Testing
- Care Management Intervention for non-cardiac chest pain
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Depression in Remission
Mechanisms of Change of Positive Interventions in Reducing Vulnerability for Depression
The purpose of this study is to understand the effects of mindfulness and fantasizing in reducing perseverative cognition underlying vulnerability for depression.
- Trial name
- MINDCOG (NCT06145984)
- Testing
- Mindfulness, Positive Fantasizing
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
ST Elevation (STEMI) Myocardial Infarction
High-Dose Rosuvastatin Preloading for Enhanced Outcomes in STEMI Patients Undergoing Primary PCI
To compare the efficacy of high dose rosuvastatin preloading vs placebo before primary PCI in terms of MACE at 30 days
- Trial name
- HEROS-PCI (NCT06924684)
- Testing
- Statin monotherapy (rosuvastatin or atorvastatin)
- Where
- 2 sites in Pakistan
- Volunteers
- 66 people
- Sponsor
- Sheikh Zayed Federal Postgraduate Medical Institute
Obesity
Baby Nutrition and Physical Activity Self-Assessment for Child Care (NAP SACC) Intervention Study
This study will evaluate the efficacy of a six-month-long intervention in improving the nutrition and physical activity environments of child care centers serving racially and ethnically diverse children from birth to two years…
- Trial name
- NCT01890681
- Testing
- Baby NAP SACC, Back to Sleep
- Where
- 3 sites in United States
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
ESR1 Gene Mutation, Advanced Breast Cancer
Current Status of Treatment for Chinese Patients With ESR1-mutated HR+/HER2-advanced Breast Cancer
This is a prospective, non-interventional real-world study to observe the efficacy and safety of different treatment regimens in patients with ESR1-mutated HR+/HER2-advanced breast cancer after failure of endocrine therapy.
- Trial name
- NCT06548919
- Testing
- Endocrine therapy, Chemotherapy Prednisone
- Where
- China
- Volunteers
- 450 people
- Sponsor
- SciClone Pharmaceuticals
Sexually Transmitted Disease, Secondary Prevention
Project Sexual Awareness for Everyone (SAFE)
This trial randomizes young Mexican American and African American women with a sexually transmitted infection to a behavioral intervention (3 three hour weekly sessions) versus control with the goal of preventing recurrent…
- Conditions
- Sexually Transmitted Disease, Secondary Prevention, Behavioral Modification, Public Health
- Trial name
- SAFE (NCT00643019)
- Testing
- SAFE Behavioral Intervention, Control
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
COPD
Inspiration Point-A Digital Pulmonary Rehabilitation Tool Management Interventions
The purpose of this study is to measure the feasibility of use of a digital pulmonary rehabilitation tool compared with standard care home program pulmonary rehabilitation.
- Trial name
- NCT03801330
- Testing
- Usual Care Pulmonary Rehabilitation Program, Pulmonary Rehabilitation Software-Based Home Program
- Where
- 4 sites in United States
- Volunteers
- 48 people
- Sponsor
- Blue Marble Rehab Inc
Hypermetropia
Use of the VisuMax Femtosecond Laser Lenticule Removal Procedure for the Correction of Hyperopia
The correction of farsightedness using ReLEx SMILE for hyperopia is focus of this investigation. The objective is to evaluate the safety and effectiveness.
- Trial name
- V1601CI (NCT03431571)
- Testing
- ReLEx SMILE
- Where
- 8 sites in China, Czechia and 4 more
- Volunteers
- 374 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec AG
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