Clinical trials: For Intervention
Video Assisted Thoracoscopic Surgery, Pain, Postoperative
Comparison of Three Different Pain Blocks for Subjects Undergoing VATS (Video Assisted Thoracoscopic Surgery) Procedure.
The purpose of this study is to compare three different pain control methods on subjects who are scheduled to undergo VATS (video-assisted thoracoscopic surgery) procedures.
- Conditions
- Video Assisted Thoracoscopic Surgery, Pain, Postoperative, Pain, Acute
- Trial name
- VATS (NCT03151434)
- Testing
- US Guided Single Shot Paravertebral Block (0.2% ropivicaine infusion), US Guided Paravertebral Catheter (0.2% ropivicaine bolus), Thoracic Epidural (0.125% bupivicaine/hydromorphone)
- Where
- United States
- Volunteers
- 147 people
- Sponsor
- Indiana University
Cancer Survivor
Southwest Harvest for Health Vegetable Gardening Intervention
"Harvest for Health" is a home-based vegetable gardening intervention that pairs cancer survivors with certified master gardeners (MGs) from the Cooperative Extension System, the education and outreach arm of land-grant…
- Trial name
- NCT04251299
- Testing
- home-based, mentored vegetable gardening program
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of New Mexico
Medication Administered in Error, Antipsychotics and Neuroleptics Toxicity
Novel Application of Simulation for Providers to Overcome Decisional Gaps in High-risk Prescribing
This pilot project aims to reduce the prescribing of high-risk medications, such as antipsychotics and benzodiazepines, to hospitalized older adults. To accomplish this, this project consists of two phases.
- Trial name
- NCT04668248
- Testing
- Simulation, Online educational training
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Brigham and Women's Hospital
Opioid-use Disorder, Mental Disorder
Start Treatment and Recovery for Opioid Use Disorder
The purpose of this study is 1) to evaluate whether emergency department-initiated medically assisted treatment with Buprenorphine/Naloxone in patients presenting with opioid use disorder will produce positive outcomes at 1 week…
- Conditions
- Opioid-use Disorder, Mental Disorder, Opioid Medication Assisted Treatment
- Trial name
- STAR (NCT04505540)
- Testing
- Bridge Clinic
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Vermont
Advance Care Planning
Culturally Tailoring an Advance Care Planning Intervention for American Indians
This project has three specific aims: (1) culturally tailor the content of the Make Your Wishes about You (MY WAY) ACP curriculum and guide for one American Indian tribe; (2) assess the feasibility of the culturally-tailored MY…
- Trial name
- NCT05304117
- Testing
- Advance Care Planning
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Western Carolina University
HIV, Trauma Exposure
A Randomized Trial of ImpACT+, a Coping Intervention for HIV Infected Women With Sexual Trauma in South Africa
ImpACT+ (Improving AIDS Care after Trauma+), is an individual-level coping intervention to address traumatic stress and HIV care engagement among South African women with sexual trauma histories.
- Trial name
- ImpACT+ (NCT04793217)
- Testing
- Improving AIDS Care After Trauma +, Adapted Problem-Solving Therapy
- Where
- South Africa
- Volunteers
- 350 people
- Sponsor
- Columbia University
Perinatal Depression
Telehealth Group Intervention for Perinatal Depressive Symptoms
The goal of the project is to evaluate for the first time, the effectiveness of using a telehealth approach to reducing perinatal depressive symptoms in diverse groups of childbearing women; urban and rural-dwelling, and from…
- Trial name
- TePOP (NCT03932760)
- Testing
- UPLIFT Program, Attention Control Group
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Utah
Acute ST Elevation Myocardial Infarction
How Effective Are Antithrombotic Therapies in Primary Percutaneous Coronary Intervention
The purpose of this study is to compare unfractionated heparin (UFH) and bivalirudin in the performance and subsequent outcomes of Primary percutaneous coronary intervention. This will be a pragmatic trial.
- Trial name
- HEAT-PPCI (NCT01519518)
- Testing
- unfractionated heparin, Bivalirudin
- Where
- United Kingdom
- Volunteers
- 1,829 people
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Arthroscopy, Bunionectomy
A Study of AQUAVAN® Injection in the Presence of Pre-Medication in Patients Undergoing Minor Surgical Procedures
The purpose of this study is to determine the safety, tolerability, and efficacy of AQUAVAN® Injection when used for mild-to-moderate sedation in patients undergoing minor surgical procedures.
- Conditions
- Arthroscopy, Bunionectomy, Osteotomy, Carpal Tunnel
- Trial name
- NCT00209560
- Testing
- fospropofol disodium
- Volunteers
- 168 people
- Sponsor
- Eisai Inc.
Phantom Limb
Cognitive Behavior Therapy (CBT) and Mirror Training for Phantom Limb Pain
The goal of this study is to test whether a combination of cognitive-behavior therapy and mirror training reduces phantom limb pain for veterans with amputations.
- Trial name
- NCT00731614
- Testing
- Cognitive Behavioral Therapy and Mirror Retraining, Supportive therapy, Mirror retraining
- Where
- 3 sites in United States
- Volunteers
- 59 people
- Sponsor
- VA Office of Research and Development
Breastfeeding, Weight Loss
Breastfeeding Support and Weight Management for Black Women
This study, in African American mothers in Detroit, will test an intervention that combines home visiting by experienced peer counselors with a smart phone-based weight control program.
- Trial name
- MamaBear (NCT03480048)
- Testing
- Breastfeeding and weight loss support
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Gestational Diabetes
Meals 4 Moms: A Multilevel Community-based Lifestyle Intervention for GDM
The goal of the project is to conduct a pilot feasibility randomized trial comparing a community-based lifestyle intervention called Meals for Moms (M4M) versus the usual care for pregnant persons diagnosed with gestational…
- Trial name
- NCT06227247
- Testing
- Meals4Moms Intervention
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- UConn Health
Chronic Myelogenous Leukemia
Cognitive Behavioral Intervention for Targeted Therapy Fatigue (CBT-TTF) Intervention
The purpose of this study is to evaluate Cognitive Behavioral Intervention for Targeted Therapy Fatigue (CBT-TTF) with fatigued chronic myelogenous leukemia (CML) patients on tyrosine kinase inhibitors (TKIs) for feasibility…
- Trial name
- NCT02592447
- Testing
- Therapy for Targeted Therapy-related Fatigue (TTF), Wait-List Control Condition (WLC)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Depression, Depression in Old Age
Trial to Test Effectiveness of Depression Intervention for Mistreated Older Adults
The investigators developed EM/PROTECT, a behavioral intervention for depressed EM (elderly mistreatment) victims, to work in synergy with EM mistreatment resolution services that provide safety planning, support services, and…
- Conditions
- Depression, Depression in Old Age, Elder Abuse, Anxiety
- Trial name
- NCT04258579
- Testing
- PROTECT with Technology Augmentation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Weill Medical College of Cornell University
Laryngologic Surgical Procedures
Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) and Short Laryngologic Surgery
The purpose of this study is to investigate whether selected, short laryngologic surgical procedures can be safely and potentially more effectively performed without the use of endotracheal tube or jet ventilation, under…
- Trial name
- NCT03091179
- Testing
- THRIVE, Endotracheal tube
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stanford University
Homelessness, Youth
Transitioning Youth Out of Homelessness 2.0 (TYOH 2.0)
Introduction: This 12-month pilot randomized controlled trial (RCT) built on previous community-engaged work and explored whether portable rent subsidies and an intervention targeting identity capital (purpose, control…
- Trial name
- NCT05781503
- Testing
- Identity Capital Intervention (Coach + Co-designed Leadership Guide), Monthly Rent Subsidies
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Parkinson's Disease
Mindfulness Based Stress Reduction for Parkinson's Disease: A Longitudinal Study
To investigate the efficacy of Mindfulness-based Stress Reduction (MBSR) to improve quality of life, cognition, and mood, as well as to determine the longevity of the treatment response in individuals with Parkinson's disease…
- Trial name
- MBSR (NCT03998462)
- Testing
- Mindfulness Based Stress Reduction, Psychoeducational Supportive Care
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- VA Office of Research and Development
Nicotine Dependence, Alcohol Use
Pilot Study on Mindfulness for Tobacco and Alcohol in University Students
A. The study follows a randomized controlled design with approximately 60 smokers with a history of alcohol abuse age 18-29. The study will compare a 7-week mindfulness intervention to a matched 7-week education intervention to…
- Trial name
- NCT01679236
- Testing
- Mindfulness Training for Smokers, Interactive Learning for Smokers
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Wisconsin, Madison
Eating Disorders, Body Image
FlexED: A Digital, Gamified Early Intervention for Eating Disorders
The goal of this clinical trial is to test a new intervention for body-image distress to reduce eating disorder symptoms in young women and girls between the ages of 15-25 years old.
- Trial name
- NCT05609409
- Testing
- FlexED
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Duke University
Diabetes, Diabetes Mellitus, Type 2
Mindfulness IN-home for Diabetes and Sleep Health
The study investigates the effects of a mindfulness intervention on sleep and subsequent cardio-metabolic risk in an adult Atlanta population aged 18 and older.
- Trial name
- MINDS (NCT04160078)
- Testing
- Mindfulness-based stress reduction (MBSR) Intervention
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Emory University
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