Clinical trials: Former Smokers
Smoking Cessation
Smoking Cessation and Sexual Health in Men
This is a 12-week clinical trial investigating the effects of smoking cessation on sexual functioning in men. This study consists of 3 sessions and provides 8 weeks of free nicotine transdermal patches.
- Trial name
- NCT00833404
- Testing
- Nicotine transdermal patch
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Texas at Austin
Cigarette Smoker, Current Smoker
18F-FSPG PET/CT in Diagnosing Early Lung Cancer in Patients With Lung Nodules
This phase II trial studies how well 18F-FSPG positron emission tomography (PET)/computed tomography (CT) work in diagnosing early lung cancer in patients with indeterminate lung nodules.
- Conditions
- Cigarette Smoker, Current Smoker, Former Smoker, Multiple Pulmonary Nodules
- Trial name
- NCT03824535
- Testing
- Computed Tomography, Fludeoxyglucose F-18, Fluorine F 18 L-glutamate Derivative BAY94-9392
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Andrei Iagaru
Nicotine Dependence, Cigarettes, Cessation, Tobacco
Reducing Nicotine Addiction in Adolescent Smokers
Adolescents are at risk for tobacco use due to factors such as impulsivity, poor perception, desire to prove themselves, and insufficient neurological development.
- Conditions
- Nicotine Dependence, Cigarettes, Cessation, Tobacco, Cessation, Smoking, Adolescent Problem Behavior
- Trial name
- NCT05477342
- Testing
- Board Game, Tobacco Cesseation Education, Combined İntervention
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Ministry of National Education, Turkey
Cessation, Smoking
Efficacy of a Smoke-Free Homes Intervention
The purpose of this study is to test whether the integration of a smoke-free homes intervention into the clinical guidelines for tobacco cessation can encourage sustained smoking cessation in low-income primary care patients.
- Trial name
- SFH 5A RCT (NCT04547686)
- Testing
- Smoke-Free Homes Intervention, Quitline
- Where
- United States
- Volunteers
- 916 people
- Sponsor
- Emory University
Stroke, Smoking Cessation
NICE: NeuroImaging in Cessation Education
The investigators aim to examine the effect on smoking cessation rate by showing stroke patients who are active smokers images of their strokes.
- Trial name
- NCT02769871
- Testing
- Neuroimages of stroke, standardized smoking cessation counseling
- Volunteers
- 20 people
- Sponsor
- Yale University
Cigarette Smoking
The Effectiveness of Smoking Cessation Guidelines in the Emergency Department
Although 78% of smokers report that a health professional has previously advised them to quit smoking, most smokers are not advised to stop smoking or offered assistance with smoking cessation during a given ED visit.
- Trial name
- NCT00756704
- Testing
- Smoking cessation guideline implementation
- Where
- 2 sites in United States
- Volunteers
- 789 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Coronary Heart Disease, Smoking Cessation
Health Education and Counseling in Smoking Cessation Behavior, Smoking Decisional Balance, and Self-efficacy
Most male smokers with coronary heart disease resume smoking after hospital discharge. The main reason for failure to quit smoking is lack of motivation.
- Conditions
- Coronary Heart Disease, Smoking Cessation, Smoking Behaviors
- Trial name
- NCT05905666
- Testing
- health education and counseling
- Where
- Taiwan
- Volunteers
- 108 people
- Sponsor
- Taipei Medical University WanFang Hospital
Cigarette Smoking, Psychological Interventions
Efficacy and Neuroimaging Mechanisms of Smoking Cessation in China
This proposed project is to assess the efficacy of CBT-based digital smoking cessation interventions in China, as well as explore its neuroimaging mechanisms.
- Conditions
- Cigarette Smoking, Psychological Interventions, Smoking Cessation
- Trial name
- NCT05788068
- Testing
- Cognitive behavior therapy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Sir Run Run Shaw Hospital
Lung Carcinoma
Iloprost in Preventing Lung Cancer in Former Smokers
This phase I trial studies the side effects and best dose of iloprost compared with a placebo in preventing lung cancer in former smokers. Chemoprevention is the use of drugs to keep cancer from forming or coming back.
- Trial name
- NCT02237183
- Testing
- Iloprost, Quality-of-Life Assessment, Questionnaire Administration
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- National Cancer Institute (NCI)
Cigarette Smoking
A Smoking Cessation Study to Understand the Biological and Functional Changes After One Year of Smoking Cessation
The purpose of this study was to understand the biological and functional changes after one year of smoking cessation and to collect data on a broad range of biomarkers of exposure (BoExp) and biomarkers of effect (BoE).
- Trial name
- RIBESC (NCT02432729)
- Where
- 5 sites in United States, Germany and 3 more
- Volunteers
- 1,184 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Lung Cancer, Tobacco Use Disorder
Screening Methods in Finding Lung Cancer Early in Current or Former Smokers
RATIONALE: Screening may help doctors find lung cancer sooner, when it may be easier to treat. PURPOSE: This clinical trial is studying screening methods to see how well they find lung cancer early in current or former smokers.
- Trial name
- Pan Can (NCT00751660)
- Testing
- laboratory biomarker analysis, screening questionnaire administration, bronchoscopic and lung imaging studies
- Where
- 6 sites in Canada
- Volunteers
- 2,504 people
- Sponsor
- British Columbia Cancer Agency
Lung Cancer
A Trial of Placebo Versus Enzastaurin for Lung Cancer Prevention in Former Smokers
To compare the difference of a marker of cellular proliferation in all bronchial biopsy specimens of former smokers stratified by lung cancer risk, collected before and after treatment per patient between the enzastaurin and…
- Trial name
- NCT00414960
- Testing
- Enzastaurin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Eli Lilly and Company
Tobacco Use Cessation
Offering Proactive Tobacco Treatment
This study uses a proactive outreach strategy, coupled with free nicotine replacement therapy (NRT) to increase the population impact of tobacco cessation treatment for diverse, low income smokers.
- Trial name
- NCT01123967
- Testing
- proactive outreach (PRO), telephone counseling (TC), Nicotine replacement therapy (NRT)
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
High Risk of Developing Lung Cancer
Lung Cancer Screening Study With Low-dose CT Scan and Blood Biomarker
Lung cancer is the number one cancer killer in the USA. Early stage lung cancer is asymptomatic. Most patients with lung cancer are usually symptomatic at diagnosis and already have advanced stage disease.
- Trial name
- NCT01700257
- Testing
- CT scan & Early CDT Lung test
- Where
- United States
- Volunteers
- 1,361 people
- Sponsor
- National Jewish Health
Cigarette Smoking-Related Carcinoma
Website Smoking Cessation Intervention for the Promotion of Smoking Cessation in Low-Income Veterans
This phase I trial studies how well a new electronic (e)-health smoking cessation program (called Vet Flexiquit) works in promoting smoking cessation in low-income veterans who may or may not be ready to quit smoking.
- Trial name
- NCT04502524
- Testing
- Smoking Cessation Intervention (New website), Smoking Cessation Intervention (Standard of care website), Health Education
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Lung Cancer
Budesonide in Treating Former and Current Smokers With Bronchial Dysplasia
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of budesonide may be an effective way to prevent bronchial dysplasia.
- Trial name
- NCT00005880
- Testing
- budesonide
- Where
- Canada
- Sponsor
- British Columbia Cancer Agency
Lung Cancer
CT Scans in Screening for Lung Cancer in Current and Former Smokers
RATIONALE: Screening tests, such as CT scanning, may help doctors find cancer cells early and plan better treatment for lung cancer.
- Trial name
- NCT00625690
- Testing
- questionnaire administration, computed tomography, evaluation of cancer risk factors
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Nebraska
Cancer and Tobacco Abuse
A Feasibility Study of Smoking Cessation Program in Radiation Oncology
To test the feasibility of an intensive behavioral and pharmacologic tobacco cessation program for radiation oncology patients and their families/companions.
- Trial name
- NCT00236288
- Testing
- Bupropion and intensive behavioral therapy
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Indiana University
HIV Infections, Smokers
Evaluation of Cardiovascular Effects of Smoking Cessation in HIV Patients
We will conduct a sub-study of "An Innovative Telephone Intervention for HIV+ Smokers," (NCT00502827) conducted by Drs. Gritz, Vidrine, and others.
- Trial name
- NCT00918073
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The University of Texas Health Science Center, Houston
Smoking Cessation, Electronic Cigarette Use
Cessation of Smoking Trial in the Emergency Department
The Cessation of Smoking Trial in the Emergency Department (CoSTED) is an National Institute for Health Research (NIHR) Health Technology Assessment (HTA) funded randomised controlled trial (RCT).
- Conditions
- Smoking Cessation, Electronic Cigarette Use, E-Cig Use, Vaping
- Trial name
- COSTED (NCT04854616)
- Testing
- CoSTED Intervention
- Where
- United Kingdom
- Volunteers
- 972 people, healthy volunteers welcome
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust