Clinical trials: Former Smokers
Chronic Obstructive Pulmonary Disease, Cardiovascular Disease
Biomarkers of Early Chronic Obstructive Pulmonary Disease (COPD) in Smokers - Longitudinal Study
This is a longitudinal observational study to identify and validate protein biomarkers for COPD (chronic obstructive pulmonary diseases) and cardiovascular disease in smokers and ex-smokers attending primary care.
- Conditions
- Chronic Obstructive Pulmonary Disease, Cardiovascular Disease, Lung Cancer
- Trial name
- NCT02076061
- Where
- Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Lund University
Smoking Cessation
Varenicline Observational Investigation In The Cessation of Smoking
The purpose of this study is to determine the safety and efficacy of varenicline in the real-world environment of smokers attending primary care in routine clinical practice with the addition of being offered behavioral support…
- Trial name
- CHOICES (NCT00669240)
- Testing
- Varenicline
- Where
- 52 sites in Belgium, Greece and 2 more
- Volunteers
- 567 people
- Sponsor
- Pfizer
Smoking, Smoking Cessation
Couples Dynamics and Smoking Cessation
This study is about investigating smoking and attempts to quit smoking in couples. Participation will help determine better treatment efforts for couples who want to quit smoking.
- Conditions
- Smoking, Smoking Cessation, Cessation, Smoking, Smoking Behaviors
- Trial name
- SCOR (NCT03885336)
- Testing
- No Interventions
- Where
- United States
- Volunteers
- 212 people
- Sponsor
- University of Southern California
Smoking Cessation
Tobacco Exposure and Influencing Factors of Smoking Cessation Among Chronic Kidney Disease Patients
The purpose of this study is to describe the tobacco exposure and characteristics of patients with Chronic Kidney Disease (CKD) who quit smoking, to identify patients' tobacco-related knowledge, attitude, and practice (KAP) and…
- Trial name
- NCT06303089
- Testing
- Questionnaires set
- Where
- China
- Volunteers
- 567 people
- Sponsor
- Sun Yat-sen University
Current Smoker, Former Smoker
Acetylsalicylic Acid Compared to Placebo in Treating High-Risk Patients With Subsolid Lung Nodules
This randomized phase II trial studies acetylsalicylic acid compared to placebo in treating high-risk patients with subsolid lung nodules. A nodule is a growth or lump that may be malignant (cancer) or benign (not cancer).
- Conditions
- Current Smoker, Former Smoker, Multiple Pulmonary Nodules, Tobacco Use Disorder
- Trial name
- NCT02169271
- Testing
- Aspirin, Laboratory Biomarker Analysis
- Where
- 2 sites in United States, Italy
- Volunteers
- 109 people
- Sponsor
- National Cancer Institute (NCI)
Respiratory Disorders
Study to Assess the Immunogenicity and Safety of GSK's Investigational Vaccine (GSK3277511A) When Given to Healthy Smokers and Ex-smokers After Administration of Shingrix Vaccine
This study will provide information regarding the sequential administration of two vaccines adjuvanted with AS01. The aim of this study is to understand immunogenicity and safety of NTHi-Mcat vaccine when administered…
- Trial name
- NCT03894969
- Testing
- GSK's investigational non-typeable Haemophilus influenzae (NTHi) and Moraxella catarrhalis (Mcat) multi-antigen vaccine (GSK3277511A) adjuvanted with AS01E, Shingrix GSK's lyophilized formulation of the herpes zoster (HZ) vaccine (GSK1437173A)
- Where
- 14 sites in Estonia, Finland and 3 more
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Precancerous Condition, Stage I Non-small Cell Lung Cancer
Sulindac in Preventing Lung Cancer in Current or Former Smokers With Bronchial Dysplasia
This randomized phase II trial is studying sulindac to see how well it works compared to a placebo in preventing lung cancer in current or former smokers with bronchial dysplasia.
- Conditions
- Precancerous Condition, Stage I Non-small Cell Lung Cancer, Tobacco Use Disorder
- Trial name
- NCT00368927
- Testing
- sulindac
- Where
- 6 sites in United States, Canada
- Volunteers
- 61 people
- Sponsor
- National Cancer Institute (NCI)
Smoking Cessation, Nicotine Dependence
Neuropsychological Prognosis Factors of Smoking Cessation
The low overall effectiveness of available smoking cessation treatment so far, indicate the need for new and more efficacious ways to help smokers maintain abstinence. Smokers are a highly heterogeneous population.
- Trial name
- NCT01554436
- Testing
- neuropsychological assessment
- Where
- France
- Volunteers
- 135 people
- Sponsor
- University Hospital, Montpellier
Tobacco Use Cessation, Sleep Disorders
Impact of Smoking Cessation on Sleep - 5
Smoking is a major health problem with a direct link to elevated heart- and lung-related problems. Nicotine is highly addictive, which makes quitting difficult and relapse after quitting highly probable.
- Trial name
- NCT00132821
- Testing
- Bupropion, Transdermal Nicotine Patch
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Smoking
Evaluation of Lung Cancer CT Screening Performance Among Former and Current Smokers
Diagnostic performance of low-dose chest CT scan combined with lung-RADS classification (version 1.1) for lung cancer screening among former and current smokers.
- Trial name
- NCT05486455
- Testing
- Low-dose chest CT scan
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Hospital St. Joseph, Marseille, France
Smoking Cessation
Interventions of Smoking Cessation During Pregnancy
The aim of this clinical trial is to test whether offering pregnant smokers a high intensity intervention for smoking cessation increases the rate of smoking cessation at the third trimester of pregnancy, compared to low…
- Trial name
- NCT01210118
- Testing
- Low intensity intervention, Higher intensity intervention
- Where
- 2 sites in Greece
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Hellenic Anticancer Society
Lung Cancer Prevention
Green Tea or Polyphenon E in Preventing Lung Cancer in Former Smokers With Chronic Obstructive Pulmonary Disease
RATIONALE: Chemoprevention is the use of certain substances to keep cancer from forming, growing, or coming back. The use of green tea or polyphenon E may prevent cancer from forming in former smokers with chronic obstructive…
- Trial name
- NCT00363805
- Testing
- green tea, Polyphenon E
- Where
- 3 sites in United States
- Volunteers
- 178 people
- Sponsor
- Sherry Chow
Tobacco Use Cessation
Study of the Effectiveness of a Virtual Reality Treatment in the Management of Smoking Cessation
Tobacco is an addiction with serious consequences: somatic, psychiatric... The number of requests for treatment for tobacco addiction is gradually increasing from year to year, but conventional treatments have limited…
- Trial name
- 3DSmoke (NCT04610931)
- Testing
- Virtual Reality-Enhanced Cognitive Behavioral Therapy (VR-CBT), cognitive behavior therapy
- Where
- France
- Volunteers
- 74 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pulmonary Disease, Chronic Obstructive
Genomic/ Proteomic/ Metabonomic Profiling in Chronic Obstructive Pulmonary Disease (COPD)
Chronic obstructive pulmonary disease (COPD) is a chronic disease characterized by progressive airflow obstruction, chronic cough and dyspnoea in advanced stages. We hope to develop a better understanding of lung disease.
- Trial name
- NCT00655694
- Testing
- sputum, blood, urine, exhaled breath, lung function
- Where
- United Kingdom
- Sponsor
- Imperial College London
Cardiovascular Disease, Oxidative Stress
Study of Chokeberry to Reduce Cardiovascular Disease Risk in Former Smokers
The purpose of this project is to determine whether chokeberry polyphenols mitigate cardiovascular disease risk in former smokers.
- Trial name
- NCT01541826
- Testing
- Chokeberry Extract, Chokeberry extract capsule, acute
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Lung Cancer, Precancerous Condition
ACAPHA in Preventing Lung Cancer in Former Smokers With Bronchial Intraepithelial Neoplasia
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming. The use of ACAPHA, a combination of six herbs, may prevent lung cancer from forming in former smokers with bronchial intraepithelial neoplasia.
- Trial name
- NCT00522197
- Testing
- multi-herbal agent ACAPHA, Sugar Pill
- Volunteers
- 90 people
- Sponsor
- British Columbia Cancer Agency
Smoking Cessation, Smoking Cessation Counselling
New Smoking Cessation Intervention in Primary Care - a Randomized Controlled Trial
Cigarette smoking remains the leading modifiable risk factor for lung cancer4 and 16 other types of cancer, as well as chronic cardiovascular and pulmonary diseases.
- Trial name
- NCT07900724
- Testing
- WillQuit App, Smoking cessation standard treatment,
- Where
- Norway
- Volunteers
- 620 people
- Sponsor
- Helse Nord-Trøndelag HF
Tobacco Use
Smartphone Application Smoking Cessation Study
The purpose of the study is to determine if using the smartphone application quitSTART can help people quit smoking and to understand how use of specific smartphone application features when trying to quit smoking is associated…
- Trial name
- NCT04623736
- Testing
- quitSTART
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Behavior, Health Risk, Implementation Science
Incentive-based and Media Literacy Informed Approaches to Improve Vaping Cessation
This study aims to evaluate the feasibility and compare the preliminary effect of vaping cessation program consisting of media literacy education and real-time text messaging support and leverage insights from behavioral…
- Conditions
- Behavior, Health Risk, Implementation Science, E Cigarette Use, Cessation, Smoking
- Trial name
- NCT05586308
- Testing
- Text-massaging suport, Financial incentive, Media literacy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Nebraska
Cigarette Smoking
Predictors of Teen Smoking-cessation
The primary objective of this research is to explore relations between impulsive behavior and smoking-cessation success among treatment-seeking teens enrolled in a quit-smoking program.
- Trial name
- NOT (NCT01141517)
- Testing
- Not-On-Tobacco smoking cessation program
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital