Clinical trials: Fortification
Diarrhea, Pneumonia
Efficacy of Bifidus DR10 and Oligo Saccharides / Micronutrient Fortification of Milk
The purpose of the study is to evaluate effect or fortifying milk with pre and probiotics or with micronutrients on prevention of diarrhea, pneumonia and other childhood illnesses and improvement in growth and development.
- Conditions
- Diarrhea, Pneumonia, Febrile Illness, Growth
- Trial name
- NCT00255385
- Testing
- Micronutrient (Zinc and Iron) fortification, Pre and Probiotic fortification
- Where
- India
- Volunteers
- 1,200 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Hemoglobin, Anemia
Nutritional Impact of a Project on Food Security and Nutrition in Children Receiving Micronutrient Powders in Colombia
The effectiveness of micronutrient powders or MNP as a strategy for the prevention of micronutrient deficiencies has been described in the literature.
- Trial name
- NCT03313089
- Testing
- "Papas más nutritivas" (PSAN)
- Where
- Colombia
- Volunteers
- 112 people
- Sponsor
- Universidad Nacional de Colombia
Anaemia
Safe and Efficacious Iron for Children in Kenya
This study will determine whether the haemoglobin response to daily home fortification for 30 days with 3mg iron as NaFeEDTA is non-inferior to 12.5 mg iron as encapsulated ferrous fumarate.
- Trial name
- SEICK (NCT02073149)
- Testing
- Low-dose iron as NaFeEDTA, Conventional dose iron as ferrous salt
- Where
- Kenya
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Human Milk Fortification, Very Low Birth Weight Baby
Enrichment of Human Milk With Human and Bovine Milk-based Fortifiers for Very Preterm Infants: a Meta-analysis
Research has shown that provision of mother's milk is the optimal way to feed very low birthweight (VLBW) infants. Many infants will require a supplement to mother's milk, pasteurized donor human milk (PDHM) compared to preterm…
- Conditions
- Human Milk Fortification, Very Low Birth Weight Baby, Human Milk Nutrition, Human Milk Feeding
- Trial name
- NCT06870318
- Testing
- No intervention; Observational study
- Where
- 2 sites in Canada, Sweden
- Volunteers
- 355 people
- Sponsor
- The Hospital for Sick Children
Iron Deficiency Anemia
Effect of Rice Fortification With Iron on Anemia Among Children
This was a double-blind community-based trial, placebo controlled. During 16 weeks, children in the intervention group (GI, n=180) received iron fortified rice, and children in the control group (GC, n=174) received rice with…
- Trial name
- NCT00727545
- Testing
- iron bisglycine chelate
- Where
- Brazil
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Growth, Necrotizing Enterocolitis
Bovine Colostrum as a Fortifier Added to Human Milk for Preterm Infants
Very preterm infants (<32 weeks gestation) with very low birth weight (VLBW, <1500 g) show immaturity of organs and have high nutrient requirements forgrowth and development.
- Conditions
- Growth, Necrotizing Enterocolitis, Late-Onset Sepsis, Feeding Intolerance
- Trial name
- FortiColos (NCT03537365)
- Testing
- Bovine Colostrum (BC) / intervention group, FM85 / control group
- Where
- 7 sites in Denmark
- Volunteers
- 252 people
- Sponsor
- Per Torp Sangild
Fractional Absorption of Zinc (Focus of the Study)
Zinc Absorption From Fortified Water
A water purifying system, called LifeStrawFamily (LSF), able to fortify water with zinc to a concentration of 4 mg/l has been developed.
- Trial name
- NCT01636583
- Testing
- LSF water without meal, LSF water and inhibitory meal, Fortified inhibitory meal with water
- Where
- Switzerland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Postprandial Hyperglycemia, Energy Expenditure
The Effect of Bread Fortification With Phosphorus and Lysine on Postprandial Glycaemia and Thermogenesis
Wheat and wheat derived products are highly consumed around the world. They constitute the major dietary source of protein and energy for many individuals.
- Trial name
- NCT03836495
- Testing
- lysine and phosphorus
- Where
- Lebanon
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Very Low Birth Weight Baby, Early Nutrition and the Preterm Infant
Optimizing Nutrition and Milk (Opti-NuM) Project
Early nutrition critically influences growth, neurodevelopment and morbidity among infants born of very low birth weight (VLBW), but current one-size-fits-all feeding regimes do not optimally support these vulnerable infants.
- Conditions
- Very Low Birth Weight Baby, Early Nutrition and the Preterm Infant, Nutritional Requirements, Human Milk Fortification
- Trial name
- Opti-NuM (NCT06870981)
- Testing
- Opti-NuM is an observational secondary use of data/samples study, the investigators will analyze information and specimens from the MaxiMoM platform RCTs. No interventions form part of this study.
- Where
- 6 sites in United States, Canada
- Volunteers
- 1,100 people
- Sponsor
- The Hospital for Sick Children
Zinc Deficiency
Impact of Targeted Zinc Fortification Programs on Plasma Zinc Concentration
The purpose of the study is to evaluate the use of plasma zinc concentration for assessing the impact of targeted zinc fortification programs.
- Trial name
- NCT00944398
- Testing
- Zinc fortified food, Zinc supplement, Non-fortified food
- Where
- Senegal
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Micronutrient Deficiency, Malnutrition, Child
Dietary Intake, Health and Micronutrient Status in Haiti
The general objective of this project is to collect information on dietary intake and nutritional status of women and young children in Haiti, to inform the design and management of national and subnational micronutrient…
- Conditions
- Micronutrient Deficiency, Malnutrition, Child, Malnutrition, Chronic Disease
- Trial name
- NCT04034381
- Testing
- No intervention (descriptive survey only)
- Where
- Haiti
- Volunteers
- 143 people
- Sponsor
- University of California, Davis
Iron Deficiency, Lead Poisoning
Iron Fortification Trail Using NaFeEDTA in Iron Deficient Lead-exposed Children
In a cross-sectional study allotted by the ethical committee of the ETH Zurich, we are investigating the extent of anemia, iron deficiency and lead intoxication in young children.
- Trial name
- NCT01573013
- Testing
- iron fortified biscuits
- Where
- Switzerland
- Volunteers
- 457 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency
Relative Bioavailability of Ferric Pyrophosphate From an Apple Juice Drink
The aim of this study is to find out how well iron is absorbed when a newly developed form of ferric pyrophosphate is added to a commercial apple juice drink.
- Trial name
- NCT00474682
- Testing
- Micronized dispersible ferric pyrophosphate
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Iron Deficiency (Without Anemia)
Absorption of Iron From Stabilized Lactoferrin: A Study in Women With Iron Deficiency
Lactoferrin (LF) is a natural iron-binding protein found in milk. It exists either in an iron-free state (apo-LF) or bound to iron (holo-LF).
- Trial name
- LOBSTER (NCT07394972)
- Testing
- FeSO4 + meal-matrix, FeSO4 + native LF + meal-matrix, FeSO4 + NaCas-LF + meal-matrix
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Nicole Stoffel
Premature Birth
Iron-fortified Parenteral Nutrition in the Prevention and Treatment of Anemia in Premature Infants
The purpose of this study is to determine whether iron-fortified PN is effective in the preventative and treatment of preterm infants. Preterm infants are at risk for anemia especially in preterm infants.
- Trial name
- NCT02743572
- Testing
- iron sucrose-1, iron sucrose-2, iron sucrose-3
- Where
- China
- Volunteers
- 129 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Healthy Individuals
Study of Vitamin D Fortification of Milk and Oil
It is a two-year longitudinal effectiveness study. A comparative study with a case-control design. Study will be conducted in Pune city. A total of up to 100 families (50 families per group) will be recruited.
- Trial name
- Tata (NCT05541094)
- Where
- India
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- Dr. Anuradha Khadilkar
Nutritional Status
A Methodology Study to Evaluate a Sitting Knee Measuring Device in Assessing Growth in Indian Children.
This methodology study will evaluate the sensitivity in using sitting knee digital caliper to measure changes in sitting knee length from over a 12-week study period amidst children in the age of 6 to 12 years in a…
- Trial name
- NCT02201225
- Testing
- Nutritional supplement with micronutrient, Nutritional supplement without micronutrient
- Where
- India
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Complementary Feeding, Linear Programming
Optimized Complementary Feeding With or Without Home Fortification Prevents Decrease of Micronutrient and Growth
Malnourished among under-five children characterized by growth faltering is a public health concern in Indonesia. It requires serious action from the governments because of the prevalence of underweight, stunting, and wasting are…
- Conditions
- Complementary Feeding, Linear Programming, Nutritional Status, Micronutrient Deficiency
- Trial name
- NCT03891589
- Testing
- Nutritional education program, Home fortification (Taburia)
- Where
- Indonesia
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Udayana University
Iron-deficiency Anemia
Iron Fortified Beverages and Application in Women Predisposed to Anemia
The objective of the study is to know if consumption of an iron fortified fruit juice containing micronized iron pyrophosphate, is useful to increase iron status in women predisposed to iron deficiency anemia.
- Trial name
- FeDrink (NCT01135576)
- Testing
- non-fortified fruit juices consumed as part of the usual diet, Iron fortified fruit juice
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- National Research Council, Spain
Pregnancy, Childhood
Formulation and Evaluation of the Efficacy of Macro- and Micronutrient Sachets on Pregnant Mothers and Children Aged 6-60 Months
The aim of the present study is formulation and production of sachets containing macronutrients and micronutrients to enrich food at home and evaluate its effectiveness on pregnant mothers and children aged 6 to 60 months living…
- Trial name
- NCT05412238
- Testing
- micro-and macro-nutrients fortified sachets
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Nutrition and Food Technology Institute