Clinical trials: Fractional Flow Reserve
Coronary Artery Disease, Percutaneous Coronary Intervention
Physiology Optimized Versus Angio-guided PCI
Angiography-derived Fractional Flow Reserve (FFR) Virtual Percutaneous Coronary Intervention (PCI) plan is superior to conventional angiography-guided PCI in obtaining a good final physiology result, which is, in turn, associated…
- Trial name
- AQVA-II (NCT05658952)
- Testing
- Microcatheter-derived FFR, Angiography-derived FFR, Angiography-guided PCI
- Where
- 2 sites in Italy
- Volunteers
- 305 people
- Sponsor
- University Hospital of Ferrara
Coronary Artery Disease, Percutaneous Coronary Intervention
Comparison of Fractional FLOW Reserve Outcomes With Drug-Coated Balloon-Based Versus Drug-Eluting Stent-Only Percutaneous Coronary Intervention Strategies
The goal of this clinical trial is to find out whether a treatment strategy based on a drug-coated balloon (DCB) achieves coronary artery function at 6 months that is not worse than a strategy using only drug-eluting stents (DES)…
- Conditions
- Coronary Artery Disease, Percutaneous Coronary Intervention, Drug Coated Balloon, Drug Eluting Stents (DES)
- Trial name
- FLOW-DCB (NCT07852689)
- Testing
- Drug-coated balloon-based intervention, Drug-eluting stent-based intervention
- Where
- 4 sites in South Korea
- Volunteers
- 100 people
- Sponsor
- Korea University Guro Hospital
Coronary Artery Disease
Fractional Flow Reserve or 3D-Quantitative-Coronary-Angiography Based Vessel-FFR Guided Revascularization
The FAST III is a randomized controlled, open-label, multicenter, international, non-inferiority, strategy trial. A total of 2228 participants will be randomized in a 1:1 fashion to either vFFR- or FFR guided revascularization.
- Trial name
- FAST III (NCT04931771)
- Testing
- vFFR guided revascularization, FFR guided revascularization
- Where
- 40 sites in France, Germany and 5 more
- Volunteers
- 2,235 people
- Sponsor
- ECRI bv
Coronary Angiography, Drug-eluting Stents
Proper Fractional Flow Reserve Criteria for Intermediate Lesions in the Era of Drug-eluting Stent
Angiographic evaluation for intermediate lesions is not always accurate. Fractional flow reserve-guided deferral strategy for these lesions showed the same event rate as routine intervention strategy.
- Conditions
- Coronary Angiography, Drug-eluting Stents, Fractional Flow Reserve, Myocardial
- Trial name
- DEFER-DES (NCT00592228)
- Testing
- Cypher, Taxus or Endeavor
- Where
- South Korea
- Volunteers
- 250 people
- Sponsor
- Seoul National University Hospital
Coronary Artery Disease, Cardiovascular Diseases
Functional Diagnostic Accuracy of Quantitative Flow Ratio in Tandem Lesions and Virtual Stenting
Quantitative Flow Ratio (QFR) is a novel method for evaluating the functional significance of coronary stenosis. Virtual stent implantation technique combined with QFR was recently developed to predict the functional significance…
- Conditions
- Coronary Artery Disease, Cardiovascular Diseases, Myocardial Ischemia, Arterial Occlusive Diseases
- Trial name
- FORTRESS (NCT03405506)
- Testing
- Quantitative Flow Ratio (QFR)
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Pulse Medical Imaging Technology (Shanghai) Co., Ltd
Coronary Artery Disease, In-stent Restenosis
CT-FFR-guided Strategy for In-stent Restenosis
This study will be a prospective, randomized clinical trial to compare standard practice guided by usual care testing to CT-FFR-guided management in patients with in-stent restenosis.
- Trial name
- NCT05611190
- Testing
- CT-FFR, Usual Care
- Volunteers
- 294 people
- Sponsor
- Yan'an Affiliated Hospital of Kunming Medical University