Clinical trials: Fracture, Ankle
Ankle Sprains, Ankle Injuries
Diagnostic Ultrasonography in Physiotherapy
Ankle injuries are among the most common traumatological injuries of the lower limb accounting for approximately 50% of all sports injuries and 25% of musculoskeletal injuries in general.
- Conditions
- Ankle Sprains, Ankle Injuries, Ankle Edema, Ankle Impingement
- Trial name
- SonograPHY (NCT05916300)
- Testing
- Diagnostic ultrasonography-guided physiotherapy group
- Where
- Czechia
- Volunteers
- 70 people
- Sponsor
- Petr Routner
Acute Fracture Surgery, Alcohol Cessation Intervention
Alcohol Cessation Intervention in an Acute Surgical Setting
Hazardous alcohol intake is an independent risk factor for postoperative complications after major and minor operations, elective and emergency procedures for men and women.
- Conditions
- Acute Fracture Surgery, Alcohol Cessation Intervention, Postoperative Complications, Infection
- Trial name
- NCT00986791
- Testing
- GSP-A
- Where
- 3 sites in Denmark
- Volunteers
- 70 people
- Sponsor
- Bispebjerg Hospital
Fixation of Lateral Malleolus in Ankle Fracture Type A&B by Plate Versus Intramedullary Screw
Plate Versus Intramedullary Screw for Lateral Malleolus Fracture in Ankle Fracture Type A&B
The aim of this study is to compare the short term : Clinical, radiographic and functional outcome, and healing time and rate of complications between fixation of lateral malleolar fracture in Danis_Weber_A\&B fracture ankle by…
- Trial name
- NCT07447336
- Testing
- Fixation of lateral malleolar fracture in Danis_Weber_A&B fracture ankle by plate versus intramedullary screw fixation
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Sohag University
Distal Fibula Fracture
Fibular Fixation in Ankle Fractures:Plate Verses Nail.
The primary objective of this study will be to evaluate the functional outcome of patients who present with a distal fibula fracture who were treated with either intermedullary nail (IMN) fixation or plate fixation.
- Trial name
- NCT02507193
- Testing
- Open reduction internal fixation, Intermedullary Nail
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Orlando Health, Inc.
Trauma
Syndesmotic Injury and Fixation in Supination-External (SE) Ankle Fractures
The aim of our study was to determine whether transfixation of unstable syndesmosis is necessary in supination-external rotation type ankle fractures.
- Trial name
- NCT01234493
- Testing
- fixation, no fixation
- Where
- Finland
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Neuropathic Pain
The Prevalence of Neuropathic Pain Pathophysiology Associated With Ankle Fracture
This application addresses the Peer Reviewed Medical Research Program Investigator-Initiated Research Award FY21 W81XWH-22-CPMRP-IIRA area of Chronic Pain Management Research Program- The investigators will utilize subjects who…
- Trial name
- AFNP (NCT06420141)
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Indiana University
Ankle Fracture - Lateral Malleolus, Post-Op Complication
Physiotherapy Versus Use of a New Ankle Trainer Device After Ankle Fracture Operation.
The study will compare the functions outcomes between two different rehabilitation protocol after operated weber b ankle fractures
- Trial name
- NCT04168307
- Testing
- Ankle trainer device, Conventional physiotherapy
- Volunteers
- 113 people
- Sponsor
- Oslo University Hospital
Femur Fracture, Tibia Fracture
Outpatient Floor Pedal Bike Utilization
The goals of this clinical trial are: to test the feasibility of identifying patients and getting patients the floor pedal bikes, to test how well floor pedal bikes help patients with lower body injuries heal, and to test methods…
- Conditions
- Femur Fracture, Tibia Fracture, Ankle Injuries
- Trial name
- NCT06586190
- Testing
- Floor Pedal Bike with Guided Instructions for Home
- Volunteers
- 20 people
- Sponsor
- Wake Forest University Health Sciences
Fracture Arm, Fracture Leg
Accuro XV Ultrasound Imaging System for BoneEnhance and Fracture Detection Algorithms
The Accuro XV is a cart-based, bedside ultrasound instrument that incorporates new signal processing-based technologies for enhanced bone and soft-tissue imaging.
- Conditions
- Fracture Arm, Fracture Leg, Wrist Injury, Ankle Injury
- Trial name
- NCT07853768
- Testing
- Accuro XV Ultrasound Imaging System
- Where
- 10 sites in United States
- Volunteers
- 25,000 people
- Sponsor
- Rivanna Medical, Inc.
Deep Vein Thrombosis, Pulmonary Embolism
Prophylaxis of Thromboembolic Complications Trial: Thromboprophylaxis Needed in Below Knee Plaster Cast Immobilization for Ankle and Foot Fractures
Objective: The purpose of this study is to determine the need for thromboprophylaxis in patients with a fracture of the lower extremity being treated conservatively in a below-knee plaster cast and to assess if both of the two…
- Trial name
- PROTECT (NCT00881088)
- Testing
- Nadroparin, Fondaparinux
- Where
- 5 sites in Netherlands
- Volunteers
- 669 people
- Sponsor
- Red Cross Hospital Beverwijk
Lateral Malleolus Fractures
Double Compression Screw Fixation for Symptomatic Non-union of Lateral Malleolar Ankle Fractures
The aim of this prospective clinical trial study is to evaluate the clinical and radiological outcomes of treating non-union of the lateral malleolar ankle fractures by double compression screw fixation technique.
- Trial name
- NCT07539922
- Testing
- Double Compression Screw Fixation for Symptomatic Non-union of Lateral Malleolar Ankle Fractures
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Sohag University
Rehabilitation of Surgically Treated Ankle Fractures
Full-Weightbearing Following Ankle Fractures Surgically Treated - The FAST-Mobility Trial
The aim of this study is to investigate complication rates and clinical outcome following mobilization and pain-dependent full weight-bearing in a large cohort of patients with surgically treated ankle fractures.
- Trial name
- NCT05419154
- Testing
- Early pain dependent weight-bearing without immobilization
- Where
- Germany
- Volunteers
- 360 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Syndesmotic Injury of the Ankle
Tightrope or Screw Fixation of Acute Tibiofibular Syndesmotic Injury
Syndesmotic injuries are common and often associated with unstable ankle fractures. The most common treatment is with a syndesmotic screw through the fibula and tibia which is later removed, usually after 10-12 weeks.
- Trial name
- TIGHTROPE-SS (NCT01275924)
- Testing
- Tightrope Syndesmosis Repair Kit, Syndesmotic screw
- Where
- 2 sites in Norway
- Volunteers
- 97 people
- Sponsor
- Sykehuset Asker og Baerum
Osteoporotic Fractures, Hip Fractures
Prediction and Secondary Prevention of Fractures
The purpose of this study is to investigate patient related factors that contribute to increased risk of recurrent fractures and to investigate patient adherence to prescribed anti-osteoporotic drugs.
- Conditions
- Osteoporotic Fractures, Hip Fractures, Wrist Fractures, Ankle Fractures
- Trial name
- NOFRACTsub (NCT02608801)
- Where
- 6 sites in Norway
- Volunteers
- 840 people
- Sponsor
- Oslo University Hospital
Ankle Fractures
Ziptight or Tricortical Screw Fixation of Acute Tibiofibular Syndesmotic Injury
Treatment of syndesmotic injury with Weber C fracture. A randomized study comparing ZipTight suture endobutton and one tricortical 3,5 mm syndesmotic screw.
- Trial name
- S16 (NCT02930486)
- Testing
- ZipTight suture endobutton, Tricortical 3.5 mm syndesmotic screw
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Vestre Viken Hospital Trust
Ankle Injuries
Early Weightbearing and Mobilization Versus Non-Weightbearing and Mobilization in Unstable Ankle Fractures
The primary objective of the investigators randomized controlled trial is to determine if early protected weightbearing and ankle range of motion after surgical treatment (open reduction internal fixation - ORIF) for ankle…
- Trial name
- NCT01196338
- Testing
- Early weight-bearing and range of motion exercises, non-weight bearing, no range of motion
- Where
- 2 sites in Canada
- Volunteers
- 110 people
- Sponsor
- University of Toronto
Ankle Fracture - Lateral Malleolus, Deltoid Ligament; Sprain (Strain) (Ankle)
Deep Deltoid Ligament Integrity in Weber B Ankle Fractures - Mini-invasive Arthroscopic Evaluation.
Prospective cohort study to evaluate the use of a NanoScopic procedure to assess deltoid ligament injuries with outcomes measured at baseline, 6 weeks, 12 weeks, 1 year and 2 years.
- Conditions
- Ankle Fracture - Lateral Malleolus, Deltoid Ligament; Sprain (Strain) (Ankle), Ankle Fractures
- Trial name
- NCT04674046
- Testing
- Nonoperative treatment, Operative treatment, Standardized education
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Ostfold Hospital Trust
Fracture Dislocation of Ankle Joint
A Prospective Randomized Pilot Study to Compare Open Versus Percutaneous Syndesmosis Repair of Unstable Ankle Fractures
This study evaluates fracture healing, anatomic reduction and return to functioning in patients with unstable Weber C type fractures of the ankle.
- Trial name
- ART (NCT02245893)
- Testing
- open reduction internal fixation (ORIF)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Achilles Tendon Rupture, Ankle Fractures
Swedish Multicenter Trial of Outpatient Prevention of Leg Clots
Lower limb immobilization is associated with high risk of complications, i.e. venous thromboembolism (VTE) and failed healing. Pharmacoprophylaxis of VTE is in leg-immobilized patients, however, low- or non-effective and…
- Conditions
- Achilles Tendon Rupture, Ankle Fractures, Venous Thromboembolism
- Trial name
- StopLegClots (NCT03259204)
- Testing
- Adjuvant IPC
- Where
- Sweden
- Volunteers
- 1,400 people
- Sponsor
- Karolinska University Hospital
Intra-Articular Fractures
Effect of Early Saline Lavage on Synovial Fluid Composition Following Intra Articular Ankle Fractures
The purpose of this study is to examine the effect of early, percutaneous, intra-articular saline lavage on the undiluted synovial fluid microenvironment during the acute phase following intra-articular fracture of the human…
- Trial name
- NCT05465382
- Testing
- Saline Lavage, No intra-articular saline lavage, Lidocaine - intra-articular injection
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Duke University