Clinical trials: Fracture, Ankle
Open Tibia Fracture, Open Dislocation of Ankle
Accelerated Flap Coverage in Severe Lower Extremity Trauma
The goal of this randomized controlled trial is to determine if accelerated flap coverage compared to standard flap coverage timing leads to improved infection-related complications in patients with open fractures and/or…
- Conditions
- Open Tibia Fracture, Open Dislocation of Ankle, Extremity Fracture Lower, Extremity Injuries Lower
- Trial name
- FLAP ATTACK (NCT06293469)
- Testing
- Accelerated Flap Coverage Surgery, Standard of Care Flap Timing
- Where
- 11 sites in United States, Australia and 2 more
- Volunteers
- 356 people
- Sponsor
- Johns Hopkins University
Ankle Fractures, Ankle Injuries
Turkish Version of the Ankle Fracture Outcome of Rehabilitation Measure (A-FORM-TR): A Multi-Centre Validation Study
Ankle fractures are common injuries that can affect a patient's mobility, mood, sleep, and everyday life for months. The Ankle Fracture Outcome of Rehabilitation Measure (A-FORM) is an English-language patient-reported outcome…
- Trial name
- A-FORM-TR (NCT07620015)
- Where
- 3 sites in Cyprus, Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Utku Gürhan
Ankle Fractures, Ankle Fracture - Lateral Malleolus
Correlation Between Intraoperative Tourniquet Use and Limb pH, Functional Measures and Patient-reported Outcomes After Ankle Fracture Surgery
This study aims to 1) characterize skeletal muscle pH during/after tourniquet use and 2) investigate any relationship between intraoperative tourniquet use and postoperative functional measures and patient-reported outcomes.
- Conditions
- Ankle Fractures, Ankle Fracture - Lateral Malleolus, Ankle Fracture, Bimalleolar, Ankle Fracture, Trimalleolar
- Trial name
- NCT05445960
- Testing
- Tourniquet
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- Oregon Health and Science University
Ankle Fractures, Deltoid Ligament; Sprain (Strain) (Ankle)
The Benefit of Repairing the Deltoid Ligament in Unstable Ankle Fractures
Ankle fractures occur in 1 out of 800 persons a year and is a common injury. The deltoid ligament is necessary for the stability of the joint and guides choice of treatment.
- Trial name
- NCT06568276
- Testing
- Additional deep deltoid ligament suture
- Where
- 9 sites in Norway
- Volunteers
- 120 people
- Sponsor
- Ostfold Hospital Trust
Ankle Sprain
Semiconductor Embedded Socks for Ankle Sprains
The goal of this clinical trial is to determine if semiconductor fabric embedded in socks can improve healing after non operative ankle sprains. The main questions it aims to answer are: 1.
- Trial name
- NCT07025733
- Testing
- Semiconductor Embedded Sock, Control Compression Sock
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Colorado, Denver
Ankle Fractures, Bimalleolar Fractures
Fibulink Syndesmosis Repair System With Early Full-Weight Bearing
The purpose of the study is to evaluate the ability of the Fibulink Syndesmosis Repair System to maintain reduction of the ankle syndesmosis.
- Conditions
- Ankle Fractures, Bimalleolar Fractures, Syndesmotic Injuries, Bimalleolar Equivalent Fracture
- Trial name
- NCT06085586
- Testing
- Early Weight Bearing, Normal Weight Bearing
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Maimonides Medical Center
Ankle Injuries
A Multicenter Randomized Trial Comparing Antiglide and Lateral Plate Fixation in Ankle Fractures
The role of operative fixation of unstable, displaced lateral malleolus fractures is well-established (Mayer, Mak, and Yablon). However, the optimal type of fixation remains the subject of debate.
- Trial name
- NCT00718302
- Testing
- Antiglide Plate, Lateral Plate
- Where
- 10 sites in United States, Canada
- Volunteers
- 249 people
- Sponsor
- Boston Medical Center
Ankle Fractures
Neuromuscular Electrical Stimulation in Foot and Ankle Surgery
This is a pilot randomized controlled trial, wherein the intervention group will undergo NMES five days a week beginning three weeks postoperative and lasting for ten weeks.
- Trial name
- NCT06370325
- Testing
- VPOD Wireless Tens Unit, Physical Therapy, Biodex
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health
Ankle Injuries
Early Weightbearing and Mobilization Versus Non-Weightbearing and Mobilization in Unstable Ankle Fractures
The primary objective of the investigators randomized controlled trial is to determine if early protected weightbearing and ankle range of motion after surgical treatment (open reduction internal fixation - ORIF) for ankle…
- Trial name
- NCT01196338
- Testing
- Early weight-bearing and range of motion exercises, non-weight bearing, no range of motion
- Where
- 2 sites in Canada
- Volunteers
- 110 people
- Sponsor
- University of Toronto
Stress Fracture Foot, Stress Fracture Ankle
Intravenous Bisphosphonate in Stress Fracture Treatment -A Randomised Controlled Double Blinded Multicenter Trial
The effect of an intravenous bisphosphonate (zoledronic acid) on healing and symptoms of stress fractures that do not respond to conservative/conventional treatment within 6 months, will be investigated.
- Trial name
- NCT03576599
- Testing
- Zoledronic Acid Injectable Product
- Where
- Norway
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Ankle Fractures, Orthopedic Procedures
Outpatient Versus Inpatient Surgery for Ankle Fractures
This study is a single center randomized controlled trail in which we compare outpatient and inpatient patients with an ankle fracture requiring surgical treatment.
- Conditions
- Ankle Fractures, Orthopedic Procedures, Surgical Procedures, Inpatient
- Trial name
- OVISAF (NCT05389436)
- Testing
- Ambulatory care, Inpatient care
- Where
- Denmark
- Volunteers
- 86 people
- Sponsor
- Christian Grundtvig Refstrup Rasmussen
Pes Planus
The Development of Flat Foot After Ankle Fractures
In this study we are trying to determine the incidence of flat foot (also called pes planus) among patients who have had an ankle fracture.
- Trial name
- NCT00507910
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Ottawa Hospital Research Institute
Ankle Fractures
Efficacy of Nasal Oxygen Therapy to Reduce Postoperative Complications in Ankle Trauma Surgery in At-risk Patients: a Randomized Pilot Study.
Ankle fractures are one of the most common surgeries in the world. After this kind of surgery, complications can occur, related to the scar or an infection. These complications are more frequent in "high-risk" patients.
- Trial name
- TOP-ANK (NCT05185115)
- Testing
- Oxygen, no oxygen therapy
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Nantes University Hospital
Bone Metastases, Fracture Nonunion
Ankle Arthrodesis Nail for 2-level Pathologic Tibial Fracture
Tibial pseudarthrosis in 83 year old patient suffering from pathologic fractures
- Conditions
- Bone Metastases, Fracture Nonunion, Bone Lesion
- Trial name
- NCT04940754
- Testing
- osteosynthesis
- Where
- Switzerland
- Volunteers
- 1 people
- Sponsor
- Orthopaedie Zentrum Zuerich
Blister, Abrasion
Assessing Foot Injuries in Infantry Recruits Wearing Different Boots
One hundred infantry recruits will be randomly assigned to two groups. Injuries will be monitored.
- Conditions
- Blister, Abrasion, Stress Fracture, Ankle Sprain
- Trial name
- NCT02810002
- Testing
- Experimental infantry boot - DEFINITE-REGULATOR, Control infantry boot
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Fracture Dislocation of Ankle Joint, Fracture Leg
Single Shot Exparel vs Catheters in Lower Extremity Trauma
This study will compare the use of single-shot Exparel, a long-acting local anesthestic, with the use of catheters that deliver a continuous flow of the short-acting local anesthetic ropivacaine.
- Conditions
- Fracture Dislocation of Ankle Joint, Fracture Leg, Fracture Femur, Fracture Lower Leg
- Trial name
- NCT07221019
- Testing
- Bupivacaine, Exparel + Bupivacaine
- Where
- United States
- Sponsor
- George Washington University
Lateral Malleolus Fracture, Minimally Invasive Surgical Procedure
Comparison of Patients Who Underwent Open and Minimally Invasive Fixation in Lateral Malleolar Fractures
The aim of this study was to compare the postoperative clinical, functional and radiological results of two different surgical methods, minimally invasive percutaneous plate osteosynthesis method and open reduction-internal…
- Conditions
- Lateral Malleolus Fracture, Minimally Invasive Surgical Procedure, Postoperative Pain, Patient Discharge
- Trial name
- NCT06753656
- Testing
- Open Surgery, Minimally Invasive Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Giresun University
Hip Disease, Heart Failure
How Does Patients' Overall Assessment of Their Health Vary Across and Within Different Disease Groups?
EQ-5D is one of the most commonly employed patient-reported outcome (PRO) measures. It is included in many of the Swedish National Quality Registers (NQRs).
- Conditions
- Hip Disease, Heart Failure, Psoriasis, Fractures, Bone
- Trial name
- SWEQR (NCT04359628)
- Where
- Sweden
- Volunteers
- 700,000 people
- Sponsor
- Vastra Gotaland Region
Ankle Fracture
The Effect of Vitamin c on Preventing Complex Regional Pain Syndrome (CRPS Type I) Following Ankle Fracture
The use of prophylactic treatment with vitamin c may prevent complex regional pain syndrome (CRPS)
- Trial name
- CRPS (NCT01338129)
- Testing
- vitamin c
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Medial Malleolus Fracture, Lisfranc Injury
Performance and Safety Evaluation of Inion CompressOn Screw in Foot and Ankle Surgeries. PMCF Investigation
The study in question is a post market clinical follow up (PMCF) study to evaluate the safety and performance of bioabsorbable headless compression screw Inion CompressOn in selected fracture, osteotomy and arthrodeses operations…
- Conditions
- Medial Malleolus Fracture, Lisfranc Injury, Lisfranc Fracture, Talus Fracture
- Trial name
- NCT05555459
- Testing
- Operation
- Where
- Finland
- Volunteers
- 125 people
- Sponsor
- Inion Oy