Clinical trials: Fracture, Ankle
Ankle Fractures, Tibia Fracture
CBD for Pain Reduction and Opioid Use After Ankle and Tibia Fracture ORIF
The purpose of this study is to evaluate the effects of administering CBD to control post-operative pain in patients undergoing ankle fracture open reduction and internal fixation, tibial plafond (pilon) open reduction and…
- Trial name
- NCT04768478
- Testing
- CBD
- Where
- United States
- Sponsor
- NYU Langone Health
Ankle Fracture
Ankle Fracture Treatment in the Elderly
The purpose of this study is to track surgical outcomes and post-operative course in patients 55 years of age or older treated for ankle fractures.
- Trial name
- NCT01444144
- Testing
- Fracture union
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Florida
Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar), Ankle Fracture - Lateral Malleolus
Rebound Pain Following Regional Anaesthesia for Ankle Fracture Surgery
Regional anaesthesia is a commonly used and effective analgesic modality in orthopaedic surgery. The benefits of peripheral nerve blocks (PNB) include better pain relief, limited opioid consumption and high patient…
- Conditions
- Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar), Ankle Fracture - Lateral Malleolus, Ankle Fracture - Medial Malleolus, Rebound Pain
- Trial name
- NCT06864312
- Testing
- continuous infusion of levobupivacaine, oxycodone
- Where
- Ireland
- Volunteers
- 120 people
- Sponsor
- University College Cork
Ankle Fractures
Hardware Removal After ORIF of Ankle Fractures
Ankle fractures account for 10 % of fractures in the adult population. A part of patients (40%) is treated surgically. After healing of the fractures, about one year after the operation, a surgery is often performed to remove the…
- Trial name
- NCT05798741
- Testing
- Hardware removal
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Hôpital Fribourgeois
Pediatric Ankle Fracture
Point-of-Care Ultrasonography for Pediatric Ankle Fracture Detection
This prospective observational study evaluated the diagnostic accuracy of point-of-care ultrasonography (POCUS) for detecting ankle fractures in children presenting to the emergency department with acute isolated ankle trauma.
- Trial name
- NCT07872124
- Testing
- Point-of-Care Ultrasonography (POCUS)
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Fracture of Fifth Metatarsal Bone
Comparison of Conservative and Operative Treatment of Jones Fracture
The study deals with the topic of treatment of Jones fracture, comparing surgical and conservative approach. The fracture occurs especially in highly active individuals.
- Trial name
- NCT04037540
- Testing
- Operational approach, Conservative approach
- Where
- Czechia
- Volunteers
- 27 people
- Sponsor
- University Hospital Ostrava
Ankle Fractures, Intermittent Pneumatic Compression
Preoperative Treatment of Malleolar Fractures
This study investigates, in a randomized setting, the use of intermittent in-cast pneumatic foot-compression (IPC) in the preoperative treatment of malleolar fractures.
- Conditions
- Ankle Fractures, Intermittent Pneumatic Compression, Comparative Study, Preoperative Care
- Trial name
- NCT02444468
- Testing
- Flowtron ACS800, Bandage
- Where
- Denmark
- Volunteers
- 96 people
- Sponsor
- Hospital of Southern Jutland
Ankle Fractures
Robot-assisted Rehabilitation of Ankle Fractures: Efficacy and Comparison With Traditional Methods
The purpose of this trial is to determine the effectiveness, safety and tolerability of robot-assisted rehabilitation using ARBOT in patients with ankle dysfunction resulting from work related ankle fractures, compared with…
- Trial name
- NCT02923479
- Testing
- Specific ankle rehabilitation by ARBOT device, General Rehabilitation, Specific ankle rehabilitation performed by physiotherapist
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- Istituto Nazionale Assicurazione contro gli Infortuni sul Lavoro
Ankle Injuries, Fracture
Lymphomyosot for Ankle Edema Following Fracture
Ankle fractures are invariably complicated by severe soft-tissue swelling which can significantly prevent surgical repair (open reduction and internal fixation - ORIF) of the fractured bone for up to two weeks.
- Trial name
- NCT00884988
- Testing
- Lymphomyosot
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Shaare Zedek Medical Center
Lateral Malleolus Fracture
A Noninferiority RCT Comparing Operative vs Nonoperative Treatment for ER-stress Positive Weber-B Unimalleolar Fractures
Current gold standard treatment for unstable (those found unstable in external rotation (ER) stress testing Weber B-type, Lauge-Hansen supination-external rotation type IV) ankle fractures is open reduction and internal fixation…
- Trial name
- NCT01758796
- Testing
- Non-operative treatment, Surgery
- Where
- Finland
- Volunteers
- 126 people
- Sponsor
- University of Oulu
Musculoskeletal Pain, Musculoskeletal Injury
The Diagnostic Accuracy of the Clinical Examination
This study examines the diagnostic accuracy of the clinical examination as compared to MRI findings
- Trial name
- NCT03850470
- Testing
- clinical examination, MRI
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- High Point University
Ankle Fractures, Osteoarthritis, Ankle
Stability of Distal Tibiofibular Syndesmosis With or Without Fixation of Posterior Fragments in Bimalleolar Fractures
Background and Rationale: Injury to the tibiofibular syndesmosis in ankle fractures is a major prognostic factor for the development of post-traumatic osteoarthritis.
- Trial name
- SYNDESMOSE (NCT07755462)
- Testing
- Surgical management of bimalleolar ankle fractures with osteosynthesis of the posterior fragments., Surgical management of bimalleolar ankle fractures without osteosynthesis of the posterior fragments
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Groupe Hospitalier Diaconesses Croix Saint-Simon
Femoral Neck Fractures, Intertrochanteric Fractures
Opioid-Free Pain Treatment in Trauma Patients
Analgesic drug study that will compare pain outcomes of opioid analgesia and opioid-free analgesia in post-operative orthopedic patients.
- Conditions
- Femoral Neck Fractures, Intertrochanteric Fractures, Femoral Shaft Fracture, Distal Femur Fracture
- Trial name
- NCT06078371
- Testing
- Opioid-free pain treatment
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Kansas Medical Center
Local Anesthesia
Result Of Use Of Wide Awake Local Anaesthesia In Fixation Of Ankle Fractures
to assess the success of wide-awake local anaesthesia In fixation of ankle fractures
- Trial name
- NCT06395987
- Testing
- Wide Awake Local Anaesthesia In Fixation Of Ankle Fractures.
- Volunteers
- 60 people
- Sponsor
- Assiut University
Ankle Fractures
AORIF Complex Ankle Fractures
The aim of this study is to evaluate the intraarticular lesions, to identify fractures specifically at risk for these, and to assess the results following arthroscopically assisted open reduction and internal fixation of complex…
- Trial name
- NCT04033848
- Testing
- Arthroscopic assisted ankle fracture treatment
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Ankle Injuries, Fracture, Ankle
Patient Education Using 3D Printed Model
Complex high energy fractures of the lower extremity are life changing injuries and are known to be associated with poor functional outcome post operatively.
- Trial name
- NCT04009252
- Testing
- 3D Model Education
- Volunteers
- 28 people
- Sponsor
- Ottawa Hospital Research Institute
Ankle Fractures
Local Multimodal Injection Versus Regional Anesthesia in Controlling Pain for Treating Rotational Ankle Fractures
The investigators plan to evaluate the efficacy in reducing post-operative pain between local multimodal analgesia as compared to regional anesthesia in rotational ankle fractures.
- Trial name
- NCT05019638
- Testing
- Regional anesthesia group, Local multimodal analgesia group
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Utah
Ankle Fractures, Leg Fracture
Sciatic Nerve Block for Ankle and Leg Fracture Manipulation in the Emergency Department
The goal of this feasibility clinical trial is to assess the acceptability of ultrasound-guided sciatic nerve block when performed at Emergency Departments for manipulation and temporary stabilization of distal leg and ankle…
- Trial name
- AnkleMan (NCT06329752)
- Testing
- Ultrasound-guided Sciatic Nerve block (20 mL of 2% Lidocaine)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Ankle Fractures, Foot Fracture
Waterproof Casting Versus Standard Casting for Short Leg Walking Casts
The purpose of the study is to determine whether the use of waterproof padding in short leg walking casts will lead to an increase in cast-related complications, as compared to the standard non-waterproof casting in children.
- Conditions
- Ankle Fractures, Foot Fracture, Ankle Sprains, Foot Sprain
- Trial name
- NCT04961957
- Testing
- Waterproof padding, Non-waterproof padding
- Where
- United States
- Sponsor
- West Virginia University
Hip Fractures, Tibial Fractures
Go Fit Fast, Recovery Trajectory Using PROMIS®, Linking PROMIS®
Prospective data will be collected in approximately 3500 patients (700 per 5 injury groups). Patients will be followed up according to the standard (routine) for up to 1 year after the treatment.
- Conditions
- Hip Fractures, Tibial Fractures, Ankle Fractures, Humeral Fracture, Proximal
- Trial name
- NCT04113044
- Testing
- All treatments will remain the standard (routine) care procedures based on individual clinician's judgment and the patient characteristics.
- Where
- 15 sites in United States, Austria and 4 more
- Volunteers
- 1,500 people
- Sponsor
- AO Innovation Translation Center