Clinical trials: Fracture
Acute Pain
Efficacy of Gabapentin vs. Placebo for Adjuvant Pain Control Following Acute Rib Fractures
A Multi-center, Randomized Controlled Trial of the Efficacy of Gabapentin vs. Placebo for Adjutant Pain Control Following Acute Rib Fractures.
- Trial name
- NCT02856750
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Denver Health and Hospital Authority
Delirium - Postoperative, Hip Fracture Surgeries
DEX-HIP Trial: Preoperative IV Dexamethasone 4 mg vs Placebo to Reduce Postoperative Delirium Burden in Adults ≥70 Undergoing Hip Fracture Surgery
This single-center, prospective, randomized, double-blind, placebo-controlled trial was conducted at the Department of Orthopaedic Surgery, JPMC, Karachi.
- Conditions
- Delirium - Postoperative, Hip Fracture Surgeries, Steroid
- Trial name
- NCT07651150
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Jinnah Postgraduate Medical Centre
Musculoskeletal Pain, Fractures, Closed
Graded Motor Imagery for Women at Risk for Developing Type I CRPS Following Closed Treatment of Distal Radius Fractures
Nearly 2 out of 10 women will sustain a distal forearm fracture throughout their lifespan.Recent longitudinal studies illustrate that as many as 1/3 of all persons who undergo closed reduction and casting for distal radius…
- Conditions
- Musculoskeletal Pain, Fractures, Closed, Distal Radius Fracture, Complex Regional Pain Syndromes
- Trial name
- NCT02957240
- Testing
- Standard Care, Motor Representation Techniques
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Minnesota
Osteoarthritis of the Shoulder, Avascular Necrosis
Database Retrieval for the Comprehensive Shoulder
This study is a retrieval of database information regarding survivorship of the Comprehensive Shoulder System family of products.
- Conditions
- Osteoarthritis of the Shoulder, Avascular Necrosis, Rheumatoid Arthritis, Prior Failed Revision
- Trial name
- NCT03409718
- Testing
- Biomet Comprehensive Shoulder System
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Zimmer Biomet
Femoral Neck Fractures, Nerve Block
Lumbar-Sacral Plexus Block vs Fascia Iliaca Block Plus Low-Dose Spinal Anesthesia for Femoral Neck Fracture Surgery
Femoral neck fracture surgery in elderly patients is frequently complicated by intraoperative hypotension and inadequate postoperative analgesia.
- Trial name
- NCT07346885
- Testing
- Lumbar and Sacral Plexus Block, Fascia Iliaca Block Combined with Low-Dose Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Forearm Fracture, Clavicle Fracture
Bone Ultrasound to Access Fracture Healing
The purpose of this study is to evaluate sequential fracture healing with radius/ulna fractures or clavicle fractures and compare ultrasound to radiographs.
- Trial name
- NCT02769117
- Testing
- Ultrasound on fractured bone, Ultrasound on contralateral intact bone
- Volunteers
- 13 people
- Sponsor
- Mayo Clinic
Calcaneus Fracture, Orthopedic Devices Associated With Misadventures
Heel-unloading Orthosis for Treatment of Calcaneus Fractures
Treatment of acute calcaneus fractures includes non- or partial weight bearing, but protocols are different and often not very specific.
- Trial name
- CALCFRO (NCT03572816)
- Testing
- Settner shoe
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Southern Denmark
Neuromuscular Blockade, Arthroplasty, Replacement, Hip
Reversal of Neuromuscular Blockade With Sugammadex or Usual Care in Hip Fracture Surgery or Joint (Hip/Knee) Replacement (P07038)
This study will assess the effect of reversal of neuromuscular blockade with sugammadex compared with reversal according to usual care (neostigmine or spontaneous reversal) on the incidence of post-surgical bleeding events and on…
- Conditions
- Neuromuscular Blockade, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee, Blood Coagulation
- Trial name
- NCT01422304
- Testing
- Sugammadex, neostigmine and glycopyrrolate or atropine
- Volunteers
- 1,198 people
- Sponsor
- Merck Sharp & Dohme LLC
Pelvic Fracture Pubic Rami Multiple - Unstable Closed
Use of Virtual Reality for Pelvic External Fixator Removal
Assessing the role of virtual reality in decreasing pain and improving patient satisfaction in outpatient removal of pelvic external fixator constructs.
- Trial name
- NCT04202315
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Washington
Post Operative Pain, Femur Fracture
Volume Dependent Effect of Pericapsular Nerve Block
In PENG block technique, the local anesthetic agent is injected between the psoas tendon and the pubic ramus to block the sensory branches of the nerves which innervates the hip capsule for providing analgesia without causing…
- Trial name
- NCT05256056
- Testing
- Bupivacain
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Distal Radial Fracture, Rehabilitation
The Effect of Mulligan and GMI on Distal Radius Proprioception
Distal radius fractures are common in the elderly population and clinical findings after treatment include limitation of joint motion, pain, and muscle weakness.
- Conditions
- Distal Radial Fracture, Rehabilitation, Mulligan Mobilization, Motor Imagery Training
- Trial name
- NCT07288060
- Testing
- Conventional Physiotherapy, Mulligan Mobilisation, Graded Motor Imagery (GMI)
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Istanbul Aydın University
Gingival Margin Elevation
Effect of Different Base Materials on Ginigiva During Gingival Margin Elevation
This study will be conducted to investigate 1. The effect of deep margin elevation with different base materials (resin modified glass ionomer, flowable composite, injectable hybrid composite) on fracture resistance and marginal…
- Trial name
- NCT06944080
- Testing
- base material(Tetric® N-Flow,Beautifil-Flow PLUS,GC fuji II LC capsule)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Minia University
Fractures, Bone
Ultrasound Detection of Radiographically Negative Fractures of Elbow in Children
Fractures of an elbow are common in children. Accurate initial diagnosis is crucial for the management of the fractures of an elbow.
- Trial name
- NCT00656162
- Where
- Israel
- Sponsor
- Hadassah Medical Organization
Orbital Fractures
Orbital Fractures Measurement: Intraoperative Versus Computed Tomography (CT) Scan
Purpose to compare the orbital fracture size measured by orbital CT scan and compare it to the actual orbital fracture size intraoperatively in patients who needed surgical intervention to correct the fracture.
- Trial name
- NCT01464541
- Testing
- operative fracture size vs CT fracture size, orbital fracture intraoperative measurement
- Where
- 2 sites in Israel
- Volunteers
- 20 people
- Sponsor
- HaEmek Medical Center, Israel
Femoral Intertrochanteric Fractures
A Prospective Multicenter Cohort Study About Internal Fixation Using PFUN Versus PFNA for Femoral Intertrochanteric Fracture
This prospective multicenter cohort study is to compare the post-operative implant failure rate between the patients with femoral intertrochanteric fracture (AO classification 31-A) using Proximal Femoral Universal Nail (PFUN)…
- Trial name
- NCT06277622
- Testing
- PFUN, PFNA
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Peking University Third Hospital
Rib Fractures
Continuous Intravenous Lidocaine Infusion Versus Placebo for Rib Fracture Analgesia
The current cornerstone of pain control for rib fractures is oral and intravenous opioids, especially in the form of patient-controlled analgesia (IV PCA), which are are associated with multiple adverse effects including…
- Trial name
- NCT04140396
- Testing
- Saline infusion, Lidocaine infusion
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Stanford University
Osteopenia, Osteoporosis
Extension Study to Evaluate the Long Term Safety and Efficacy of Denosumab in the Treatment of Osteoporosis
The primary objective was to describe the safety and tolerability of up to 10 years or 7 years denosumab administration as measured by adverse event monitoring, immunogenicity and safety laboratory parameters in participants who…
- Trial name
- NCT00523341
- Testing
- Denosumab
- Volunteers
- 4,550 people
- Sponsor
- Amgen
Trauma (Including Fractures), Trauma Abdomen
5 Minute 'HOT' Trauma CT Rates Of Detection Study
Many injured patients receive urgent CT imaging to identify major injury. CT imaging of trauma patients is often time critical and the accurate detection of life-threatening findings on this CT is essential.
- Conditions
- Trauma (Including Fractures), Trauma Abdomen, Trauma Blunt, Trauma Centers
- Trial name
- NCT07314437
- Testing
- Education
- Where
- United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital Plymouth NHS Trust
Spine Fracture, Osteoporosis
Controlled Reduction of AO Spine B3 Fractures in Ankylosing Spinal Disorders Using an Inflatable Positioning Device: Technical Note and Retrospective Single-centre Case Series
Retrospective observational
- Conditions
- Spine Fracture, Osteoporosis, Spondylitis, Ankylosing
- Trial name
- NCT07847320
- Volunteers
- 23 people
- Sponsor
- Diakonie-Klinikum Stuttgart
Femur Fracture
Radiographic Influences of Bisphosphonate Treatment on Femur
Although there is strong evidence that bisphosphonates prevent certain types of osteoporotic fractures, there are concerns that these medications may be associated with rare atypical femoral fractures (AFF).
- Trial name
- NCT01969279
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Tomidahama Hospital