Clinical trials: Fracture
Geriatric Hip Fracture
Geriatric Hip Fractures Caregiver Programme
Objective: To study whether fracture hip patients can be benefited from the empowerment program Hypothesis to be tested Primary hypothesis: empowerment program can improve the patient's functional recovery.
- Trial name
- NCT05393349
- Testing
- Empowering the patient and caregiver for early and safe discharge of patients with geriatric hip fractures
- Where
- Hong Kong
- Volunteers
- 125 people
- Sponsor
- The University of Hong Kong
Inguinal Hernia, Pelvic Fracture
Corona Mortis in Patients Undergoing TEP for Inguinal Hernia
This study aim to describe the presence, type and size of Corona mortis (CMOR) in patients undergoing total extraperitoneal (TEP) inguinal hernia repair procedures.
- Conditions
- Inguinal Hernia, Pelvic Fracture, Acetabular Fracture, Bleeding
- Trial name
- NCT04303442
- Testing
- TEP
- Where
- Bulgaria
- Volunteers
- 300 people
- Sponsor
- Sofia Med Hospital
Sickle Cell Disease, Sickle Cell Anemia
Sickle Cell Disease (SCD) Bone Pain Study
A prospective study to determine how low bone mineral density and/or vertebral compression fractures associate with pain in adults with sickle cell disease
- Conditions
- Sickle Cell Disease, Sickle Cell Anemia, Low Bone Density, Osteoporosis
- Trial name
- NCT05283148
- Testing
- Dual-energy X-ray absorptiometry, Vertebral fracture analysis, Adult Sickle Cell Quality of Life Measurement System pain impact questionnaire
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of California, Davis
Myocardial Infarction, Stroke
Women's Health Initiative Strong and Healthy Study
The WHISH trial applies state-of-the science behavioral principles and currently available technologies to deliver a physical activity intervention without face-to-face contact to ~25,000 older U.S. women expected to consent.
- Conditions
- Myocardial Infarction, Stroke, Cardiovascular Mortality, Hip Fractures
- Trial name
- WHISH (NCT02425345)
- Testing
- Physical Activity
- Volunteers
- 49,331 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Chronic Kidney Diseases, Bone Loss
Bone in CKD Alkali Response (BICARb Pilot Trial)
The goal of this clinical trial is to test whether potassium citrate improves skeletal health in adults and children with chronic kidney disease.
- Trial name
- BICARb (NCT05918029)
- Testing
- Potassium Citrate Extended Release Oral Tablet, Potassium Citrate and Citric Acid Oral Solution
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Albert Einstein College of Medicine
Chronic Patellar Tendinopathy, Chronic PT
Platelet-Rich Plasma (PRP) Injection for the Treatment of Chronic Patellar Tendinopathy
The goal of this study is to find an effective treatment for chronic patellar tendinopathy (PT). Investigators will conduct a 32-week randomized controlled clinical trial to determine whether platelet rich plasma (PRP) injections…
- Trial name
- PRP (NCT01843504)
- Testing
- platelet rich plasma, saline
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Femoral Neck Fractures
A Prospective Multicenter Cohort Study About Internal Fixation Using FNS Versus MCS for Femoral Neck Fracture
This prospective multicenter cohort study is to compare the post-operative implant failure rate between the patients with femoral neck fracture (AO classification 31-B) using Femoral Neck System (FNS) versus Multiple Cancellous…
- Trial name
- NCT04462172
- Testing
- FNS, MCS
- Where
- China
- Volunteers
- 290 people
- Sponsor
- Peking University Third Hospital
Humerus Pathological Fracture
A Safety and Efficacy Study of the Treatment of Impending and Actual Pathological Fractures in the Humerus From Metastatic Bone Disease
The purpose of this study is to collect safety and performance data of the Photodynamic Bone Stabilization System (PBSS) when used for the treatment of painful impending and actual fractures of the humerus secondary to metastatic…
- Trial name
- NCT02373904
- Testing
- Photodynamic Bone Stabilization System
- Where
- 6 sites in Austria, Germany and 1 more
- Volunteers
- 14 people
- Sponsor
- IlluminOss Medical, Inc.
Acute Humerus Fractures
Safety and Efficacy Study of the Treatment of Humerus Fractures
The purpose of this study is to collect safety and performance data on the use of the Photodynamic Bone Stabilization System (PBSS) when used to provide stabilization and alignment for the treatment of acute humerus fractures.
- Trial name
- NCT02394080
- Testing
- Photodynamic Bone Stabilization System
- Where
- 6 sites in Germany, Netherlands
- Volunteers
- 44 people
- Sponsor
- IlluminOss Medical, Inc.
Metatarsal Stress Fracture, Stress Fracture of Tibia
Photobiomodulation Therapy for the Treatment of Lower Extremity Stress Fractures in a Military Training Setting
The goal of this clinical trial is to compare photobiomodulation therapy (PBMT) in addition to standard of care in the treatment of tibial and metatarsal bone stress injuries in a military training setting.
- Trial name
- PM12 (NCT05843864)
- Testing
- Photobiomodulation Therapy with Standard Physical Therapy
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Brooke Army Medical Center
Rib Fractures
Lidocaine Patches in Elderly Patients With Traumatic Rib Fractures
Many patients are prescribed lidocaine patches for rib fractures despite mixed evidence to their efficacy. The outcome of this trial offers significant benefit to patient care if it finds benefit of their use or if it does not.
- Trial name
- NCT05714631
- Testing
- 4% Lidocaine Patch
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Hallux Valgus and Bunion (Disorder), Morton Neuroma
Feasibility of Specific Anesthesia of the Forefoot Preserving the Sensitivity of the Heel for Foot Surgery
Foot surgery is a painful surgery that is usually scheduled in outpatients. A good management of analgesia is the crucial point.
- Conditions
- Hallux Valgus and Bunion (Disorder), Morton Neuroma, Metatarsal Fracture, Ingrown Nail
- Trial name
- DISTIB (NCT03504462)
- Testing
- Specific block of medial and lateral plantar nerves
- Where
- France
- Volunteers
- 27 people
- Sponsor
- CMC Ambroise Paré
Vertebral Compression Fractures, Osteoporotic Vertebral Compression Fractures
Circumferential Vertebral Reconstruction of Osteoporotic Compression Fractures Using a Novel Bipedicular Peek Implant
The RECONSTRUCT study is a multi-center, prospective, single arm, post-market, pilot study to evaluate clinical and radiologic outcome data regarding the use of the Vertebral Implant PEEK (VIP) implant in the treatment of…
- Trial name
- RECONSTRUCT (NCT05337696)
- Testing
- Vertebral Implant PEEK Procedure, Vertebral Implant PEEK (VIP) implant
- Where
- 4 sites in United States
- Volunteers
- 23 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Fractures, Bone, Serious Fall-related Injuries
Working to Increase Stability Through Exercise
The investigators propose a 36-month multi-center randomized effectiveness trial to compare the impact of an Enhanced Usual Care (Control) intervention, with Exercise Coaching (Exercise), on Serious Fall-Related Injuries (SFI) in…
- Trial name
- WISE (NCT02714257)
- Testing
- Enhanced Usual Care plus Exercise Coaching
- Where
- United States
- Volunteers
- 1,139 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Distal Radius Fracture
Perioperative Glucocorticoid Administration in the Treatment of Adult Distal Radius Fractures
The purpose of this investigation is to compare functional outcome measures and range of motion for patients receiving glucocorticoid (GC) injections versus those not receiving GCs for the treatment of distal radius fractures.
- Trial name
- NCT03898154
- Testing
- Dexamethasone, Methylprednisolone
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- C. Liam Dwyer
Fractured Tooth, Decayed Tooth
TetricCAD Crown Clinical Study
This investigation will be a clinical trial to study the performance of a new resin-based ceramic material for crowns. The material has been approved by the FDA for patient treatment.
- Conditions
- Fractured Tooth, Decayed Tooth, Unsatisfactory Restoration of Tooth
- Trial name
- NCT03716817
- Testing
- Tetric CAD
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan
Skull Base Pathology
Olfactory Function Following Endoscopic Endonasal Skull Base Surgery
The purpose of this study is to compare a subject's sense of smell before and after endoscopic endonasal surgery to remove a skull base abnormality (i.e.
- Trial name
- UPSIT (NCT02165969)
- Testing
- endoscopic endonasal surgery with UPSIT
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Ricardo L. Carrau, MD
Orthopedic Disorder, Trauma
An Imaging Framework for Clinically Testing New Treatments to Prevent Post-traumatic OA
The immediate goal of the proposed research is to test the value of a new low-cost, low-dose standing CT system for efficient early detection of both joint degeneration and elevated contact stress.
- Conditions
- Orthopedic Disorder, Trauma, Ankle Fractures, Post-traumatic Osteoarthritis
- Trial name
- NCT03809520
- Testing
- pedCAT
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- J L Marsh
Rib Fractures
Treatment of Adult Traumatic Rib Fractures With Percutaneous Cryoneurolysis
The purpose of this research study is to examine the effectiveness of using the Iovera Smart Time 190, for ultrasound-guided cryoneurolysis, in trauma patients 18-64 years old with rib fractures that are not candidates for…
- Trial name
- Trauma-PC2 (NCT05330611)
- Testing
- Cryoneurolysis of Intercostal Nerves, Standard of Care
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Stanford University
Subchondral Cysts, Subchondral Bone Edema
SCP Hip Outcomes Study
Post-market clinical outcomes study to collect data on the short- and long-term outcomes for subjects who are undergoing or have undergone the Subchondroplasty® (SCP®) Procedure in the hip in a standard clinical setting.
- Conditions
- Subchondral Cysts, Subchondral Bone Edema, Bone Marrow Edema, Insufficiency Fractures
- Trial name
- NCT03494660
- Testing
- Subchondroplasty Procedure with AccuFill
- Where
- 6 sites in United States
- Volunteers
- 77 people
- Sponsor
- Zimmer Biomet