Clinical trials: Fracture Fixation, Internal
Lisfranc Fracture, Arthrodesis
The BFF Study- The Better to Fix or Fuse Study
The aim of the proposed study is to define the optimal treatment for Lisfranc fracture-dislocation, either primary arthrodesis (PA) or open reduction and internal fixation (ORIF), regarding the quality of life, complications…
- Conditions
- Lisfranc Fracture, Arthrodesis, Internal Fixation, Quality of Life
- Trial name
- NCT04519242
- Testing
- Surgery
- Where
- Netherlands
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Fracture Fixation, Internal
A Clinical Study to Evaluate the Safety and Efficacy of Biologic Hollow Bone Screws
Traditional fracture fixation devices can cause corrosion, allergies, and stress shielding effects. They often require removal after healing, risking secondary damage.
- Trial name
- NCT06942247
- Testing
- Active Comparator: Fracture Fixation (Inion Freedom Screws), Experimental: Fracture Fixation (Biological Hollow Bone Screws)
- Where
- China
- Volunteers
- 160 people
- Sponsor
- FengYafei
Clavicle Fracture
Benefit of Surgical Hardware Removal Following Clavicle Fracture
Little is known about the beneficial aspects of elective implant removal following plate osteosynthesis of displaced clavicle fractures.
- Trial name
- NCT04343118
- Testing
- Hardware Removal
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Technical University of Munich
Mandibular Fractures
Computer Guided Screw Holes Locating Guide and Custom-made Plates
Preoperative CT. Virtual reduction of broken segments on software. Gain occlusion. Design surgical screw holes locating guide. Design the custom-made plates. Print the screw holes locating guide and the custom-made plate.
- Trial name
- NCT05647460
- Testing
- computer guided screw holes locating guide and custom-made plates, conventional plates
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Acetabular Fracture
RCT Determining Best Treatment for Geriatric Acetabular Fractures
There is debate over the best management for acetabular (hip) fractures that occur within the geriatric population. Geriatric patients, 60 years or older, are at greater risk for operative complications because they tend to have…
- Trial name
- GeriTab (NCT03419182)
- Testing
- Open Reduction internal Fixation, Open Reduction Internal Fixation with Total Hip Arthroscopy
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of Maryland, Baltimore
Fracture Fixation, Internal, Distal Radius Fracture
RemeOs™ DrillPin for Fixation of Distal Radius Fractures in Children
This is a pre-market, single-arm, open-label, monocenter clinical investigation evaluating the safety and performance of the magnesium (Mg)-based bioresorbable RemeOs™ DrillPin for surgical fixation of distal radius fractures in…
- Trial name
- NCT07028541
- Testing
- Magnesium-based bioresorbable DrillPin for fixation of distal radius fractures in children
- Volunteers
- 20 people
- Sponsor
- Bioretec Ltd.
Femoral Neck Fractures
Hemiarthroplasty or Internal Fixation for Displaced Femoral Neck Fractures
An estimated 1.6 million patients sustain a hip fracture every year, about half of these are intracapsular femoral neck fractures.
- Trial name
- NCT00464230
- Testing
- Bipolar hemiarthroplasty (Charnley/Hastings), Internal fixation with two parallel screws (Olmed)
- Where
- Norway
- Volunteers
- 220 people
- Sponsor
- Ullevaal University Hospital
Radius Fracture Distal, Pain, Postoperative
Auricular Acupuncture As Part Of A Multimodal Regimen After Distal Radius Open Reduction and Internal Fixation
This randomized controlled trial will test the hypothesis that patients receiving an intraoperative auricular acupuncture protocol will require less postoperative opioid analgesic use compared to those who do not receive…
- Trial name
- NCT05974254
- Testing
- Acupuncture
- Where
- United States
- Sponsor
- Baylor College of Medicine
Learning Curves and Outcomes of Simulation-based Training
Is Two-on-one Instruction in Virtual Reality Simulation-based Training of Operating Fractures of the Hip for Medical Students as Effective as One-on-one Instruction
The training of orthopedic surgeons has historically relied heavily on an apprenticeship model as the primary way of teaching the various procedures an aspiring surgeon needs to master.
- Trial name
- NCT06612619
- Testing
- Dyad instruction
- Where
- Denmark
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Calcaneus Fracture
Osteosynthesis of Intraarticular Calcaneal Fractures: Arthroscopically Assisted Percutaneous Technique Versus Sinus Tarsi Approach
In this randomized controlled trial, the outcomes of two surgical techniques for intraarticular calcaneal fractures will be evaluated and compared.
- Trial name
- NCT04372251
- Testing
- Sinus tarsi approach (STA), Percutaneous Arthroscopically Assisted Osteosynthesis (PACO)
- Where
- 5 sites in Norway
- Volunteers
- 70 people
- Sponsor
- Ostfold Hospital Trust
Femoral Fractures
Nails Versus Plates for Femur Fractures in Dar es Salaam, Tanzania
This is a prospective observational study of patients with femur fractures in Dar es Salaam, Tanzania comparing two different surgical techniques: intramedullary nailing (IMN) and open reduction internal fixation (ORIF) with a…
- Trial name
- NCT01548456
- Testing
- Intramedullary Nailing, Open Reduction Internal Fixation
- Where
- Tanzania
- Volunteers
- 332 people
- Sponsor
- University of California, San Francisco
Flail Chest
MatrixRIB Implants for Surgical Stabilization of Flail Chest Injuries: A Registry
The purpose of this observational study is to document the treatment of serial rib fractures with MatrixRIB implants in a registry.
- Trial name
- MatrixRIB (NCT00810251)
- Testing
- MatrixRIB (FDA Approval # K081623)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Legacy Biomechanics Laboratory
Femoral Neck Fractures, Undisplaced Fracture
Hips Screws or (Total) Hip Replacement for Undisplaced Femoral Neck Fractures in Elderly Patients (HipSTHeR)
A registerbased RCT will investigate whether arthroplasty can decrease the reoperation rate compared to internal fixation for patients with an undisplaced femoral neck fracture (Garden I-II).
- Trial name
- HipSTHeR (NCT03966716)
- Testing
- Arthroplasty, Internal Fixation
- Where
- 25 sites in Sweden
- Volunteers
- 1,440 people
- Sponsor
- Uppsala University
BKP, Osteoporotic Vertebral Compression Fracture
Randomized Controlled Trial of Internal Fixation Reconstruction With Stent Screw in the Treatment of Kummell's Disease
This study is a multicenter, prospective, double-blind, randomized controlled trial using a parallel two-arm design to investigate whether the postoperative 6-month quality of life, vertebral stability, complication of patients…
- Conditions
- BKP, Osteoporotic Vertebral Compression Fracture, Kummell's Disease, Stent-screw-assisted Internal Fixation
- Trial name
- NCT06093087
- Testing
- SAIF, BKP
- Volunteers
- 70 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Trochanteric Fracture of Femur, Osteoporotic Fracture of Femur
FARE Augmentation of Proximal Femoral Fractures With CaS/HA and Systemic ZA
The goal of this clinical trial is to investigate the new bone formation around a metal device in the femoral head in patients with osteoporotic hip fractures undergoing surgical treatment with nails.
- Conditions
- Trochanteric Fracture of Femur, Osteoporotic Fracture of Femur, Hip Fractures, Bone Density, Low
- Trial name
- NCT06135298
- Testing
- OSTEOSYNTHESIS, Zoledronic acid, CERAMENT BONE VOID FILLER (BVF)
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Aksaray University
Surgery--Complications, Tibia Fracture
Immediate Mobilization After Plate Osteosynthesis of Proximal Tibial Fractures - A Cohort Study
The purpose of this study is to investigate if immediate mobilization with weight bearing as tolerated following surgery with plates and screws after a fracture of the shinbone near the knee is possible without increased risk.
- Conditions
- Surgery--Complications, Tibia Fracture, Early Ambulation
- Trial name
- IMOP (NCT03314623)
- Testing
- Weight bearing as tolerated
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Slagelse Hospital
Femoral Shaft Fracture
This is a Study to Verify if Tranexamic Acid Can Reduce the Anemia After a Femoral Shaft Fractures Surgery
The investigators are going to evaluate if adding Tranexamic Acid in femoral shaft fractures surgery can lead to any advantages to the participants, namely if it can reduce post-operative anaemia, blood loss, blood transfusion…
- Trial name
- ORL-ORT-023 (NCT04803591)
- Testing
- Tranexamic Acid
- Sponsor
- Christian Candrian
Subcondylar Process of Mandible Open Fracture, Facial Nerve Injuries
Evaluation of Preauricular Retromandibular Anteroparotid Versus Retromandibular Through Parotid Approach
Of all the bones in the maxillofacial area, the condylar process is the most susceptible to fracture. The incidence of condylar fracture accounts for 25% to 50% of all mandibular fractures.
- Trial name
- NCT03803150
- Testing
- PRA approach, RT approach
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Leg Injuries, Fracture
Soft Part Management for Surgical Fractures of the Lower Limb
The assessment consists in comparing corticoids injection versus placebo in surgery of lower limb fractures The aim of study is to assess (state cutaneous, efficacy, safety) corticoids injection on a prospective, randomized…
- Conditions
- Leg Injuries, Fracture, Edema
- Trial name
- ICOMI (NCT03915223)
- Testing
- leg fracture
- Where
- France
- Volunteers
- 104 people
- Sponsor
- University Hospital, Clermont-Ferrand
Infections, Infected Wound
PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation
This is a Phase III clinical randomized control trial to investigate differences between patient with an infected nonunion treated by PO vs. IV antibiotics.
- Conditions
- Infections, Infected Wound, Nonunion of Fracture, Injury Leg
- Trial name
- POvIV2 (NCT05699174)
- Testing
- Standard of Care PO (oral) antibiotics, Standard of Care Intravenous (IV) antibiotics
- Where
- 13 sites in United States
- Volunteers
- 250 people
- Sponsor
- Major Extremity Trauma Research Consortium