Clinical trials: Fracture Pelvis
Hip Fracture
An Inpatient Rehabilitation Model of Care Targeting Patients With Cognitive Impairment
Hip fractures are a danger to an individual's mobility, independence and ability to live in the community. When patients have a cognitive impairment (such as dementia or delirium) they do not recover as well or go back to their…
- Trial name
- NCT01566136
- Testing
- Rehabilitation Model of Care
- Where
- Canada
- Volunteers
- 198 people
- Sponsor
- University Health Network, Toronto
Hip Fractures
Treatment Efficacy of Leg Cycling as Part of Physiotherapy Treatment in Elderly Patients With Hip Fracture
This study aims to evaluate whether a combination of cycling training as part of physiotherapy treatment will contribute more than conventional physiotherapy treatment for elderly patients after hip fracture surgery in their…
- Trial name
- NCT02407444
- Testing
- Physiotherapy treatment & leg cycling, Physiotherapy treatment & music listening
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Rabin Medical Center
Hip Fractures
Latin America Hip Fracture Mortality Study
The purpose of this study is to estimate the survival proportion one year after surgery for intertrochanteric fracture in older adults in Latin America.
- Trial name
- LAMOS (NCT01650064)
- Where
- 16 sites in Argentina, Brazil and 6 more
- Volunteers
- 168 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Fracture of Pelvis (Disorder)
Abaloparatide and Pelvic Fracture Healing
This is a prospective randomized, double-blinded, placebo-controlled, phase 2, three-month study of the efficacy of abaloparatide in postmenopausal women and men ≥ 50 years of age with acute fractures of the pelvis (n=78).
- Trial name
- NCT04249232
- Testing
- Abaloparatide 80 micrograms per Pen dose
- Where
- 3 sites in United States
- Volunteers
- 48 people
- Sponsor
- Hospital for Special Surgery, New York
Sarcopenia in Elderly, Frailty
Safety and Efficacy of Isomyosamine in Reducing Inflammation and Treating Muscle Loss in Older Adults After Hip or Thigh Bone Fractures
This Phase II clinical study investigates the safety and effectiveness of a new drug, Isomyosamine, in patients with sarcopenia or frailty, conditions associated with aging and muscle weakness.
- Conditions
- Sarcopenia in Elderly, Frailty, Frailty/Sarcopenia, Frailty in Older Adults
- Trial name
- NCT06942182
- Testing
- Isomyosamine 250mg
- Volunteers
- 60 people
- Sponsor
- TNF Pharmaceuticals, Inc.
Hip Fractures, Osteoporosis
Secondary Prevention of Osteoporotic Fractures in Residents of Long-Term Care Facilities
Osteoporotic fractures of the hip are a major cause of admission to long-term care facilities. Such fractures put patients at high risk for further fractures, pain and disability.
- Trial name
- NCT00280943
- Testing
- Long-term care facilities in the intervention arm will receive education and feedback audit on performance
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Duke University
Femoral Neck Fractures
Dual Mobility Cups in Hip Fracture Patients
Our aim is to develop a strategy that reduces the risk of dislocations after total hip arthroplasty surgery performed due to femoral neck fracture.
- Trial name
- DUALITY (NCT03909815)
- Testing
- Dual mobility cup, Standard cup
- Where
- 2 sites in Sweden, United Kingdom
- Volunteers
- 1,600 people
- Sponsor
- Uppsala University
Fractures, Bone
Continuous Passive Motion Following Fixation of Pelvic and Knee Fractures
The investigators will directly compare the visual analog scale scores and narcotic pain medication requirements in the patients who have continuous passive motion (CPM) versus those who do not during the course of the hospital…
- Trial name
- NCT04389749
- Testing
- CPM
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Cincinnati
Pelvic Fracture
Single Trans-sacral Screw Versus Two Iliosacral Screws
1. To compare Single Trans-sacral screw fixation vs. two Ilio-Sacral screws fixation as regard time for starting weight bearing. 2. To compare between functional outcome using the Majeed Pelvic Score.
- Trial name
- NCT03944174
- Testing
- Fixation of unstable pelvic fractures
- Volunteers
- 60 people
- Sponsor
- Assiut University
Pelvic Fracture
A Prospective Study of Early Mechanical Stabilization and Bleeding in Disruption of the Pelvic Ring
The objective of this study is to evaluate the effect of earlier placement of Circumferential Pelvic Compression (CPC) on resuscitative measures required for life-threatening pelvic ring injuries and to guide the development of…
- Trial name
- EMS-BIND (NCT03977168)
- Testing
- Application of circumferential pelvic compression (CPC) device
- Where
- 11 sites in United States
- Volunteers
- 600 people
- Sponsor
- Major Extremity Trauma Research Consortium
Hip Fracture, Anemia
IRONCARE: Iron Treatment in Older Patients With Hip Fractures
The aim of this study is to investigate the effects of intravenous (IV) iron therapy compared to alternate-day oral iron treatment and no supplementation in older patients with hip fractures.
- Conditions
- Hip Fracture, Anemia, Iron, Placebo - Control
- Trial name
- NCT07659184
- Testing
- Ferric Derisomaltose, Oral Iron (Ferrous sulphate)
- Where
- 5 sites in Denmark
- Volunteers
- 528 people
- Sponsor
- University of Aarhus
Congestive Heart Failure, Chronic Obstructive Pulmonary Disease
Patient Oriented Discharge Summary Impact Study
Improving the patient experience has become a major focus of quality improvement efforts in Ontario and in health systems worldwide.
- Conditions
- Congestive Heart Failure, Chronic Obstructive Pulmonary Disease, Pneumonia, Hip Fracture
- Trial name
- PODS (NCT02673892)
- Testing
- Patient Oriented Discharge Summary
- Where
- Canada
- Volunteers
- 581 people
- Sponsor
- University Health Network, Toronto
Fracture Femur, Elderly
Feasibility of Integrating Local Vibration Into Rehabilitation of Elderly Patients After Hip Fracture
Fractures of the upper end of the femur in elderly patients are the 2nd most common fracture. A fracture leads to a syndrome of psychomotor maladjustment, encouraged by pain and aggravated by hospitalisation.
- Trial name
- ORTHOBOOSTER-P (NCT07309965)
- Testing
- Initial Assessment, Standard rehabilitation programme combined with local vibration sessions, Final assessment
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Hospices Civils de Lyon
Thromboembolism
Melagatran/Ximelagatran Versus Enoxaparin for the Prevention of Venous Thromboembolic Events
This study is being carried out to study the efficacy and safety of treatment with melagatran injection followed by ximelagatran tablets in preventing blood clots, compared with enoxaparin for a period of 5-6 weeks.
- Trial name
- EXTEND (NCT00206089)
- Testing
- EXANTA
- Where
- 125 sites in Austria, Belgium and 14 more
- Volunteers
- 3,300 people
- Sponsor
- AstraZeneca
Hip Fracture Surgery
A Non-inferiority Study Comparing Two Heparin Sodium Preparations in Hip Fracture Surgery
The primary objective and endpoints of the study is compare the efficacy of two products containing heparin sodium, evaluating if the formulation produced by Eurofarma can be considered non-inferior to the reference product.
- Trial name
- HEP-SC (NCT01352039)
- Testing
- Heparin Sodium - Eurofarma, Heparin Sodium - APP Pharmaceuticals
- Where
- 5 sites in Brazil
- Volunteers
- 544 people
- Sponsor
- Eurofarma Laboratorios S.A.
Hip Fracture
PBM and Hip Fracture
The main objective of this study was to describe the application of PBM strategies in patients undergoing surgery for hip fractures, their outcomes between 2022 and 2024, and the factors associated with the transfusion of red…
- Trial name
- NCT07908836
- Where
- Spain
- Volunteers
- 829 people
- Sponsor
- Hospital del Rio Hortega
Osteoporosis, Hip Fracture
Randomized Trial of Osteoporosis Intervention Strategies in Hip Fracture Patients
Patients with hip fractures have suffered the most devastating consequence of osteoporosis; and yet, they are rarely if ever tested or treated for the condition, even though they remain at high risk of recurrent fracture.
- Trial name
- NCT00175175
- Testing
- Allied health professional-run osteoporosis service ("case-management")
- Where
- Canada
- Volunteers
- 220 people
- Sponsor
- University of Alberta
Geriatric Hip Fracture
A Comparative Evaluation of Nottingham Hip Fracture Score (NHFS) and Acute Physiology and Chronic Health Evaluation (APACHE) II Score to Predict 30-day Mortality in Geriatric Patients Above 60 Years Undergoing Hip Fracture Surgery.
This study aims to compare the Nottingham Hip Fracture Score (NHFS) and the Acute Physiology and Chronic Health Evaluation II (APACHE II) score in predicting 30-day mortality in geriatric patients over 60 years old undergoing hip…
- Trial name
- NCT06598566
- Testing
- Nottingham Hip Fracture Score (NHFS) score, Acute Physiology and Chronic Health Evaluation (APACHE)-II score
- Where
- India
- Volunteers
- 182 people
- Sponsor
- Tata Main Hospital
Fracture of Hip
Rehab After Hip Fracture With Wearable Device
A randomized control trial, including two intervention arms with different methods for rehabilitation after hip fracture, conducted among persons with the need of rehabilitation in their own home.
- Trial name
- NCT04906265
- Testing
- Intervention, Control
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Lund University
Hip Fracture, Hip Fracture Surgeries
External Validation of Ten Prediction Models for 30-day Mortality Following Hip Fracture
This study aims to externally validate ten existing prediction models with a low risk of bias for 30-day mortality following hip fracture.
- Trial name
- PROTECT (NCT06961253)
- Where
- Netherlands
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- JointResearch