Clinical trials: Fracture Risk Assessment
Fracture
Risk Taking and Fracture Study
Boys suffer a disproportionately large number of fractures compared to girls (55-60%). This study aims to determine why this is the case by identifying risk factors for wrist fractures.
- Trial name
- NCT01768598
- Testing
- Fracture - Boys, Fracture - Girls, Non Fracture - Boys
- Where
- 2 sites in Canada
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- Canadian Institutes of Health Research (CIHR)
Post Operative Surgical Site Infection
Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT 2
The PRCT evaluates infection outcomes as well as fracture and antibiotic-related complications to include the emergence of resistant bacteria associated with two different antibiotic strategies in the treatment of Gustilo type…
- Trial name
- SEXTANT 2 (NCT04678154)
- Testing
- Standard of care, Vancomycin and Tobramycin
- Where
- 31 sites in United States
- Volunteers
- 600 people
- Sponsor
- Major Extremity Trauma Research Consortium
Postmenopausal
A Study to Evaluate the Efficacy and Safety of HLX14 vs. Denosumab Prolia® in Postmenopausal Women With Osteoporosis at High Risk of Fracture
This is a randomized, double-blind, international multicentre, parallel-controlled phase III clinical study. The study plans to enroll 478 postmenopausal women with osteoporosis at high risk of fracture, whom will be randomized…
- Trial name
- NCT05352516
- Testing
- HLX14, Prolia®
- Where
- 38 sites in China
- Volunteers
- 514 people
- Sponsor
- Shanghai Henlius Biotech
Osteoporosis
FORCE (Falls, Fracture, and Osteoporosis Risk Control Evaluation) Study
Falls and osteoporosis-related fractures cause substantial morbidity and mortality in the elderly, and are an increasingly important public health concern.
- Trial name
- NCT00465387
- Testing
- Falls, Fractures & Osteoporosis Risk Assessment & Management
- Volunteers
- 400 people
- Sponsor
- Group Health Centre
Osteoporosis
Bone UltraSonic Scanner (BUSS) Clinical Optimization Study
The aim of this clinical study using Bone UltraSonic Scanner (BUSS) is to obtain clinical data which will help to optimize the BUSS examination procedure and its diagnostic algorithms for assessment of bone conditions.
- Trial name
- BUSS (NCT01056432)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Artann Laboratories
Echocardiography, Hip Fractures
Preoperative Focused Cardiac Ultrasound in Hip Fracture Surgery (PrEcho)
The primary objective of this study is to investigate the impact of preoperative focused transthoracic ultrasound (FOCUS) on intraoperative hypotension and postoperative complications in hip fracture surgery.
- Conditions
- Echocardiography, Hip Fractures, Risk Assessment, Anesthesia
- Trial name
- PrEcho (NCT05862493)
- Testing
- FOCUS echocardiography
- Volunteers
- 100 people
- Sponsor
- Umeå University
Postmenopausal Osteopenia
Effects of Kinect-based Virtual Reality Training in Postmenopausal Women With Osteopenia
Osteopenia is a clinical term to define the declined Bone Mineral Density (BMD) as per the normal reference values but not low enough to meet osteoporotic diagnostic criteria.
- Trial name
- NCT04862910
- Testing
- Kinect Based Virtual Reality Training, Control Group
- Where
- 2 sites in Pakistan
- Volunteers
- 52 people
- Sponsor
- Riphah International University
AI (Artificial Intelligence), Osteoporosis
Evaluation of Dora Care for Supporting Fracture Liaison Services (FLS)
What is the study about? This study is testing "Dora", an AI-powered assistant that can make phone calls to patients, for use in the Fracture Liaison Service (FLS).
- Conditions
- AI (Artificial Intelligence), Osteoporosis, Outpatient, Telemedicine
- Trial name
- NCT07464171
- Testing
- Dora call
- Volunteers
- 217 people
- Sponsor
- Ufonia
Osteoporosis, Osteoporotic Fractures
An Assessment of Treatment Adherence of Osteoporosis Patients From a Biopsychosocial Perspective
This observational study aims to learn about the psychosocial risk factors of osteoporosis (OP) patients. The main question it aims to answer is: Which biopsychosocial factors affect OP patients' fragility fracture risk regarding…
- Conditions
- Osteoporosis, Osteoporotic Fractures, Psychosocial Functioning, Medication Adherence
- Trial name
- NCT05943600
- Where
- Turkey (Türkiye)
- Volunteers
- 585 people
- Sponsor
- Istanbul University
Intercostal Nerve Injury
Evaluation of Intercostal Neuralgia in Patients With Chest Tube Insertion After Traumatic Rib Fracture
Traumatic rib fractures are common injuries following blunt chest trauma, often requiring chest tube insertion to manage complications such as pneumothorax or haemothorax.
- Trial name
- NCT07308587
- Testing
- Chest tube insertion
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Sunnybrook Health Sciences Centre
Osteoporosis, Osteopenia
The Impact of Hormonal Contraceptive Use and Lifestyle Factors on Fracture Risk and Bone Quality in Young Female Adults
The study on hand is based on a cross-sectional design and aims to acquire 1) descriptive data on the physical state and health condition of female soldiers in the German armed forces.
- Conditions
- Osteoporosis, Osteopenia, Fracture Reduction, Body Composition
- Trial name
- FH (NCT06608862)
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Bundeswehr University Munich
Osteoporosis in Post-menopausal Women, Osteoporosis
Intravenous Infusion of Human Mesenchymal Stem Cells (HMM910 ) in Postmenopausal Women With Osteoporosis at High Risk of Fracture
The primary objective of this study is to evaluate the safety and tolerability of human umbilical cord-derived mesenchymal stem cells for injection (HMM910 ) in postmenopausal women with osteoporosis who are at high risk of…
- Trial name
- NCT06949137
- Testing
- Human Umbilical Cord-derived Mesenchymal stem cell
- Where
- China
- Volunteers
- 9 people
- Sponsor
- HELP Therapeutics Co., Ltd.
Osteoporotic Fracture
Preventing the Risk of Osteoporotic Fracture in Premenopausal Women by a Spa Residential Physical Activity Program
Osteoporosis is an increasing public health problem. Involution of bone mass in women is due to a reduction in sensitivity of the bone to the mechanical stress due to the slow-down of the bone turnover after 35 years old.
- Trial name
- ThermOs (NCT03570008)
- Testing
- 9 days spa residential program, 3 sessions of 10 minutes per day of physical exercise
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Rheumatoid Arthritis
Impact of Bone Mineral Density on Fracture Risk Assessment in RA
This study investigates whether incorporating bone mineral density (BMD) into FRAX calculations changes fracture risk assessment and influences treatment decisions in rheumatoid arthritis (RA) patients.
- Trial name
- NCT06718985
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Neck of Femur Fracture
Assessment of the Risk of Contralateral Non Simultaneous Neck of Femur Fracture in the Elderly.
Neck of femur fractures are common in the elderly and are the source of significant morbidity and mortality. This study is based on a new technique developed in Ben Gurion University, with which investigators are able to asses…
- Trial name
- NCT02577081
- Testing
- CAT scan (CT scan)
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Meir Medical Center
Postmenopausal Osteoporosis
Efficacy and Safety of QL1206 in the Treatment of Postmenopausal Osteoporosis With High Fracture Risk
A randomized, double-blind, two-group parallel, placebo-controlled clinical Phase III trial to compare the efficacy and safety of QL1206 and placebo in postmenopausal women with osteoporosis at high risk of fracture
- Trial name
- NCT04128163
- Testing
- QL1206
- Where
- China
- Volunteers
- 440 people
- Sponsor
- Qilu Pharmaceutical Co., Ltd.
Osteoporosis, Fracture
Develop and Validate Ultrasonic Device for Osteoporotic Fracture Risk Assessment
Study to demonstrate that the Bone UltraSonic Scanner (BUSS) can aid in detection of osteoporosis and predict prevalent osteoporotic fractures.
- Conditions
- Osteoporosis, Fracture, Aging
- Trial name
- BUSS03 (NCT01123421)
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Artann Laboratories
Fibrous Dysplasia/McCune-Albright Syndrome
Assessment of Femoral Failure Load and Fracture Risk in Rare Bone Disorders Using MEKANOS Tool. Case Study of Fibrous Dysplasia of Bone/McCune Albright Syndrome
The issue of rare diseases has become a public health priority. In France, a national plan for rare diseases was published in 2004.
- Trial name
- MEKADYS (NCT07507942)
- Testing
- Application of MEKANOS tool to CT scans
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
Osteoporosis, Fracture
Mobile Device to Help FRAX® Screening
Background: The Taiwanese FRAX® (Fracture Risk Assessment Tool) calculator is available online for clinical use. Our Taiwanese Osteoporosis Clinical Treatment Guidelines suggests using the American high risk cut-points for…
- Trial name
- NCT01930656
- Where
- Taiwan
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Osteoporosis, Osteoporotic Fracture of Vertebra
Development and Evaluation of an Exercise Intervention for Prevention of Vertebral Osteoporosis and Deformity in Postmenopausal Women
Osteoporotic fractures of the vertebrae (bones in the back) cause substantial pain and disability. Exercise could help to prevent these fractures by increasing bone strength and improving posture.
- Conditions
- Osteoporosis, Osteoporotic Fracture of Vertebra, Postural, Thoracic Kyphosis
- Trial name
- NCT04660825
- Testing
- A resistance band exercise programme, Control
- Where
- United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Loughborough University